6P7N
 
 | | Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (2:2 complex) | | Descriptor: | Cas12a, MAGNESIUM ION, anti-CRISPR VA4, ... | | Authors: | Knott, G.J, Liu, J.J, Doudna, J.A. | | Deposit date: | 2019-06-06 | | Release date: | 2019-08-21 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a.
Elife, 8, 2019
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4WYQ
 | | Crystal structure of the Dicer-TRBP interface | | Descriptor: | Endoribonuclease Dicer, Poly(UNK), RISC-loading complex subunit TARBP2 | | Authors: | Wilson, R.C, Doudna, J.A. | | Deposit date: | 2014-11-18 | | Release date: | 2014-12-17 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Dicer-TRBP Complex Formation Ensures Accurate Mammalian MicroRNA Biogenesis.
Mol.Cell, 57, 2015
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7KFU
 | | Cas6-RT-Cas1--Cas2 complex | | Descriptor: | Cas2, Cas6-RT-Cas1 | | Authors: | Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G. | | Deposit date: | 2020-10-14 | | Release date: | 2021-03-31 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex.
Nat Commun, 12, 2021
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7KFT
 | | Partial Cas6-RT-Cas1--Cas2 complex | | Descriptor: | Cas2, Cas6-RT-Cas1 | | Authors: | Hoel, C.M, Wang, J.Y, Doudna, J.A, Brohawn, S.G. | | Deposit date: | 2020-10-14 | | Release date: | 2021-03-31 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural coordination between active sites of a CRISPR reverse transcriptase-integrase complex.
Nat Commun, 12, 2021
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2X04
 | | Crystal structure of the PABC-TNRC6C complex | | Descriptor: | POLYADENYLATE-BINDING PROTEIN 1, SULFATE ION, TRINUCLEOTIDE REPEAT-CONTAINING GENE 6C PROTEIN | | Authors: | Jinek, M, Fabian, M.R, Coyle, S.M, Sonenberg, N, Doudna, J.A. | | Deposit date: | 2009-12-04 | | Release date: | 2010-01-19 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Structural Insights Into the Human Gw182-Pabc Interaction in Microrna-Mediated Deadenylation
Nat.Struct.Mol.Biol., 17, 2010
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2XXA
 | | The Crystal Structure of the Signal Recognition Particle (SRP) in Complex with its Receptor(SR) | | Descriptor: | 4.5S RNA, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | Authors: | Ataide, S.F, Schmitz, N, Shen, K, Ke, A, Shan, S, Doudna, J.A, Ban, N. | | Deposit date: | 2010-11-09 | | Release date: | 2011-03-02 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.94 Å) | | Cite: | The Crystal Structure of the Signal Recognition Particle in Complex with its Receptor.
Science, 331, 2011
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4ZT0
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4ZT9
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5K4C
 | | Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 2 | | Descriptor: | Eukaryotic translation initiation factor 3 subunit D, GLYCEROL | | Authors: | Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D. | | Deposit date: | 2016-05-20 | | Release date: | 2016-07-27 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.698 Å) | | Cite: | eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
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5K4B
 | | Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 1 | | Descriptor: | CHLORIDE ION, Eukaryotic translation initiation factor 3 subunit D | | Authors: | Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D. | | Deposit date: | 2016-05-20 | | Release date: | 2016-07-27 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.399 Å) | | Cite: | eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
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5K4D
 | | Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 3 | | Descriptor: | Eukaryotic translation initiation factor 3 subunit D | | Authors: | Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D. | | Deposit date: | 2016-05-20 | | Release date: | 2016-07-27 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
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1HQ1
 | | STRUCTURAL AND ENERGETIC ANALYSIS OF RNA RECOGNITION BY A UNIVERSALLY CONSERVED PROTEIN FROM THE SIGNAL RECOGNITION PARTICLE | | Descriptor: | 4.5S RNA DOMAIN IV, MAGNESIUM ION, POTASSIUM ION, ... | | Authors: | Batey, R.T, Sagar, M.B, Doudna, J.A. | | Deposit date: | 2000-12-13 | | Release date: | 2001-01-03 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle.
J.Mol.Biol., 307, 2001
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2OIH
 | | Hepatitis Delta Virus gemonic ribozyme precursor with C75U mutation and bound to monovalent cation Tl+ | | Descriptor: | HDV ribozyme, THALLIUM (I) ION, U1 small nuclear ribonucleoprotein A | | Authors: | Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. | | Deposit date: | 2007-01-11 | | Release date: | 2007-03-27 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
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2OJ3
 | | Hepatitis Delta Virus ribozyme precursor structure, with C75U mutation, bound to Tl+ and cobalt hexammine (Co(NH3)63+) | | Descriptor: | COBALT HEXAMMINE(III), HDV RIBOZYME, THALLIUM (I) ION, ... | | Authors: | Ke, A, Ding, F, Batchelor, J.D, Doudna, J.A. | | Deposit date: | 2007-01-12 | | Release date: | 2007-03-27 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural roles of monovalent cations in the HDV ribozyme.
Structure, 15, 2007
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1DUL
 | | STRUCTURE OF THE RIBONUCLEOPROTEIN CORE OF THE E. COLI SIGNAL RECOGNITION PARTICLE | | Descriptor: | 4.5 S RNA DOMAIN IV, MAGNESIUM ION, POTASSIUM ION, ... | | Authors: | Batey, R.T, Rambo, R.P, Lucast, L, Rha, B, Doudna, J.A. | | Deposit date: | 2000-01-17 | | Release date: | 2000-02-28 | | Last modified: | 2020-10-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the ribonucleoprotein core of the signal recognition particle.
Science, 287, 2000
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1DRZ
 | | U1A SPLICEOSOMAL PROTEIN/HEPATITIS DELTA VIRUS GENOMIC RIBOZYME COMPLEX | | Descriptor: | MAGNESIUM ION, PROTEIN (U1 SMALL RIBONUCLEOPROTEIN A), RNA (HEPATITIS DELTA VIRUS GENOMIC RIBOZYME), ... | | Authors: | Ferre-D'Amare, A.R, Zhou, K, Doudna, J.A. | | Deposit date: | 1998-09-01 | | Release date: | 1999-02-16 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of a hepatitis delta virus ribozyme.
Nature, 395, 1998
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4AL5
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4AN8
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4AL7
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4AL6
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6MCB
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6NY3
 | | CasX ternary complex with 30bp target DNA | | Descriptor: | CasX, DNA Non-target strand, DNA target strand, ... | | Authors: | Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A. | | Deposit date: | 2019-02-10 | | Release date: | 2019-02-27 | | Last modified: | 2019-12-25 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature, 566, 2019
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6NY2
 | | CasX-gRNA-DNA(45bp) state I | | Descriptor: | CasX, DNA Non-target strand, DNA target strand, ... | | Authors: | Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A. | | Deposit date: | 2019-02-10 | | Release date: | 2019-02-27 | | Last modified: | 2019-12-25 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature, 566, 2019
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6NY1
 | | CasX-gRNA-DNA(30bp) State II | | Descriptor: | CasX, DNA Non-target strand, DNA target strand, ... | | Authors: | Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A. | | Deposit date: | 2019-02-10 | | Release date: | 2019-02-27 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | CasX enzymes comprise a distinct family of RNA-guided genome editors.
Nature, 566, 2019
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1KH6
 | | Crystal Structure of an RNA Tertiary Domain Essential to HCV IRES-mediated Translation Initiation. | | Descriptor: | JIIIabc | | Authors: | Kieft, J.S, Zhou, K, Grech, A, Jubin, R, Doudna, J.A. | | Deposit date: | 2001-11-29 | | Release date: | 2002-04-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation.
Nat.Struct.Biol., 9, 2002
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