8Q4H
 
 | a membrane-bound menaquinol:organohalide oxidoreductase complex RDH complex | Descriptor: | (~{Z})-1,2-bis(chloranyl)ethene, CO-METHYLCOBALAMIN, IRON/SULFUR CLUSTER, ... | Authors: | Dongchun, N, Ekundayo, B, Henning, S, Julien, M, Holliger, C, Cimmino, L. | Deposit date: | 2023-08-07 | Release date: | 2023-10-18 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Structure of a membrane-bound menaquinol:organohalide oxidoreductase. Nat Commun, 14, 2023
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8RCR
 
 | human TRPM4 in SMA apo | Descriptor: | CHOLESTEROL, Transient receptor potential cation channel subfamily M member 4 | Authors: | Ekundayo, B, Prakash, A, Christian, G, Anne, F.H, Sabrina, G, Mey, B, Daniela, R, Martin, L, Jean, S.R, Henning, S, Hugues, A, Dongchun, N. | Deposit date: | 2023-12-07 | Release date: | 2024-12-18 | Last modified: | 2025-02-05 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Identification of a binding site for small molecule inhibitors targeting human TRPM4. Nat Commun, 16, 2025
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8RCU
 
 | human TRPM4 in SMA IBA | Descriptor: | 4-chloranyl-2-[2-(3-iodanylphenoxy)ethanoylamino]benzoic acid, CHOLESTEROL, Transient receptor potential cation channel subfamily M member 4 | Authors: | Ekundayo, B, Prakash, A, Christian, G, Anne, F.H, Sabrina, G, Mey, B, Daniela, R, Martin, L, Jean, S.R, Henning, S, Hugues, A, Dongchun, N. | Deposit date: | 2023-12-07 | Release date: | 2024-12-18 | Last modified: | 2025-02-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Identification of a binding site for small molecule inhibitors targeting human TRPM4. Nat Commun, 16, 2025
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8RD9
 
 | human TRPM4 in SMA NBA | Descriptor: | 4-chloranyl-2-(2-naphthalen-1-yloxyethanoylamino)benzoic acid, CHOLESTEROL, Transient receptor potential cation channel subfamily M member 4 | Authors: | Ekundayo, B, Prakash, A, Christian, G, Anne, F.H, Sabrina, G, Mey, B, Daniela, R, Martin, L, Jean, S.R, Henning, S, Hugues, A, Dongchun, N. | Deposit date: | 2023-12-07 | Release date: | 2024-12-18 | Last modified: | 2025-02-05 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Identification of a binding site for small molecule inhibitors targeting human TRPM4. Nat Commun, 16, 2025
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7ZSD
 
 | cryo-EM structure of omicron spike in complex with de novo designed binder, local | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, de novo designed binder | Authors: | Pablo, G, Sarah, W, Alexandra, V.H, Anthony, M, Andreas, S, Zander, H, Dongchun, N, Shuguang, T, Freyr, S, Casper, G, Priscilla, T, Alexandra, T, Stephane, R, Sandrine, G, Jane, M, Aaron, P, Zepeng, X, Yan, C, Pu, H, George, G, Elisa, O, Beat, F, Didier, T, Henning, S, Michael, B, Bruno, E.C. | Deposit date: | 2022-05-06 | Release date: | 2023-03-01 | Last modified: | 2023-05-24 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | De novo design of protein interactions with learned surface fingerprints. Nature, 617, 2023
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7ZSS
 
 | cryo-EM structure of D614 spike in complex with de novo designed binder | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Pablo, G, Sarah, W, Alexandra, V.H, Anthony, M, Andreas, S, Zander, H, Dongchun, N, Shuguang, T, Freyr, S, Casper, G, Priscilla, T, Alexandra, T, Stephane, R, Sandrine, G, Jane, M, Aaron, P, Zepeng, X, Yan, C, Pu, H, George, G, Elisa, O, Beat, F, Didier, T, Henning, S, Michael, B, Bruno, E.C. | Deposit date: | 2022-05-08 | Release date: | 2023-03-01 | Last modified: | 2024-11-13 | Method: | ELECTRON MICROSCOPY (2.63 Å) | Cite: | De novo design of protein interactions with learned surface fingerprints. Nature, 617, 2023
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7ZRV
 
 | cryo-EM structure of omicron spike in complex with de novo designed binder, full map | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Envelope glycoprotein, ... | Authors: | Pablo, G, Sarah, W, Alexandra, V.H, Anthony, M, Andreas, S, Zander, H, Dongchun, N, Shuguang, T, Freyr, S, Casper, G, Priscilla, T, Alexandra, T, Stephane, R, Sandrine, G, Jane, M, Aaron, P, Zepeng, X, Yan, C, Pu, H, George, G, Elisa, O, Beat, F, Didier, T, Henning, S, Michael, B, Bruno, E.C. | Deposit date: | 2022-05-05 | Release date: | 2023-03-08 | Last modified: | 2024-11-13 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | De novo design of protein interactions with learned surface fingerprints. Nature, 617, 2023
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