7ZSD

cryo-EM structure of omicron spike in complex with de novo designed binder, local

Summary for 7ZSD

Entry DOI	10.2210/pdb7zsd/pdb
EMDB information	14922 14930
Descriptor	Spike glycoprotein, de novo designed binder, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	sars-cov2, de novo, design binder, spike, rbd, receptor binding domain, antiviral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	2
Total formula weight	31534.50
Authors	Pablo, G.,Sarah, W.,Alexandra, V.H.,Anthony, M.,Andreas, S.,Zander, H.,Dongchun, N.,Shuguang, T.,Freyr, S.,Casper, G.,Priscilla, T.,Alexandra, T.,Stephane, R.,Sandrine, G.,Jane, M.,Aaron, P.,Zepeng, X.,Yan, C.,Pu, H.,George, G.,Elisa, O.,Beat, F.,Didier, T.,Henning, S.,Michael, B.,Bruno, E.C. (deposition date: 2022-05-06, release date: 2023-03-01, Last modification date: 2023-05-24)
Primary citation	Gainza, P.,Wehrle, S.,Van Hall-Beauvais, A.,Marchand, A.,Scheck, A.,Harteveld, Z.,Buckley, S.,Ni, D.,Tan, S.,Sverrisson, F.,Goverde, C.,Turelli, P.,Raclot, C.,Teslenko, A.,Pacesa, M.,Rosset, S.,Georgeon, S.,Marsden, J.,Petruzzella, A.,Liu, K.,Xu, Z.,Chai, Y.,Han, P.,Gao, G.F.,Oricchio, E.,Fierz, B.,Trono, D.,Stahlberg, H.,Bronstein, M.,Correia, B.E. De novo design of protein interactions with learned surface fingerprints. Nature, 617:176-184, 2023 Cited by PubMed: 37100904 DOI: 10.1038/s41586-023-05993-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.29 Å)

Structure validation