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PDB: 33 件
4OO7
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THE 1.55A CRYSTAL STRUCTURE of NAF1 (MINER1): THE REDOX-ACTIVE 2FE-2S PROTEIN
分子名称: CDGSH iron-sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER
著者Tamir, S, Eisenberg-Domovich, Y, Colman, A.R, Stofleth, J.T, Lipper, C.H, Paddock, M.L, Jenning, P.A, Livnah, O, Nechushtai, R.
登録日2014-01-31
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties.
Acta Crystallogr.,Sect.D, 70, 2014
1RXK
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crystal structure of streptavidin mutant (M3) a combination of M1+M2
分子名称: 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Streptavidin
著者Eisenberg-Domovich, Y, Pazy, Y, Nir, O, Raboy, B, Bayer, E.A, Wilchek, M, Livnah, O.
登録日2003-12-18
公開日2004-05-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural elements responsible for conversion of streptavidin to a pseudoenzyme.
Proc.Natl.Acad.Sci.USA, 101, 2004
1RXH
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Crystal structure of streptavidin mutant L124R (M1) complexed with biotinyl p-nitroanilide (BNI)
分子名称: 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Streptavidin
著者Eisenberg-Domovich, Y, Pazy, Y, Nir, O, Raboy, B, Bayer, E.A, Wilchek, M, Livnah, O.
登録日2003-12-18
公開日2004-05-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural elements responsible for conversion of streptavidin to a pseudoenzyme
Proc.Natl.Acad.Sci.USA, 101, 2004
1RXJ
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Crystal structure of streptavidin mutant (M2) where the L3,4 loop was replace by that of avidin
分子名称: 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Streptavidin
著者Eisenberg-Domovich, Y, Pazy, Y, Nir, O, Raboy, B, Bayer, E.A, Wilchek, M, Livnah, O.
登録日2003-12-18
公開日2004-05-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Structural elements responsible for conversion of streptavidin to a pseudoenzyme
Proc.Natl.Acad.Sci.USA, 101, 2004
1I9H
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CORE STREPTAVIDIN-BNA COMPLEX
分子名称: 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, STREPTAVIDIN
著者Livnah, O, Huberman, T, Wilchek, M, Bayer, E.A, Eisenberg-Domovich, Y.
登録日2001-03-20
公開日2001-09-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Chicken avidin exhibits pseudo-catalytic properties. Biochemical, structural, and electrostatic consequences.
J.Biol.Chem., 276, 2001
7P0O
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mitoNEET bound to M1 molecule
分子名称: 2-benzamido-4-[(2~{R})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, 2-benzamido-4-[(2~{S})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, CDGSH iron-sulfur domain-containing protein 1, ...
著者Livnah, O, Eisenberg-Domovich, Y, Marjault, H.B, Nechushtai, R.
登録日2021-06-30
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters.
Commun Biol, 5, 2022
7P0P
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NAF-1 bound to M1 molecule
分子名称: 2-benzamido-4-[(2~{R})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, CDGSH iron-sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER
著者Livnah, O, Eisenberg-Domovich, Y, Marjault, H.B, Nechushtai, R.
登録日2021-06-30
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters.
Commun Biol, 5, 2022
1NQN
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Structure of Avm-W110K (W110K mutant of avidin)
分子名称: Avidin
著者Pazy, Y, Eisenberg-Domovich, Y, Laitinen, O.H, Kulomaa, M.S, Bayer, E.A, Wilchek, M, Livnah, O.
登録日2003-01-22
公開日2003-07-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dimer-Tetramer Transition between Solution and Crystalline States of Streptavidin and Avidin Mutants.
J.Bacteriol., 185, 2003
1NQM
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Structure of Savm-W120K, streptavidin mutant
分子名称: BIOTIN, Streptavidin
著者Pazy, Y, Eisenberg-Domovich, Y, Laitinen, O.H, Kulomaa, M.S, Bayer, E.A, Wilchek, M, Livnah, O.
登録日2003-01-22
公開日2003-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Dimer-Tetramer Transition between Solution and Crystalline States of Streptavidin and Avidin Mutants.
J.Bacteriol., 185, 2003
4OOA
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CRYSTAL STRUCTURE of NAF1 (MINER1): H114C THE REDOX-ACTIVE 2FE-2S PROTEIN
分子名称: CDGSH iron-sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER
著者Tamir, S, Eisenberg-Domovich, Y, Conlan, A.R, Stofleth, J.T, Lipper, C.H, Paddock, M.L, Mittler, R, Jennings, P.A, Livnah, O, Nechushtai, R.
登録日2014-01-31
公開日2014-07-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties.
Acta Crystallogr.,Sect.D, 70, 2014
3S2R
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ATChloroNEET (H87C mutant)
分子名称: AT5g51720/MIO24_14, FE2/S2 (INORGANIC) CLUSTER
著者livnah, O, Eisenberg-Domovich, Y, nechushtai, R.
登録日2011-05-17
公開日2012-05-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Arabidopsis thaliana ChloroNEET, a Member of the New NEET Family of Human Proteins, is Involved in Development, Senescence and Iron Metabolism.
To be Published
3S2Q
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The crystal structure of AT5g51720 (AT-NEET)
分子名称: AT5g51720/MIO24_14, FE2/S2 (INORGANIC) CLUSTER, ZINC ION
著者Livnah, O, Eisenberg-Domovich, Y, Nechushtai, R.
登録日2011-05-17
公開日2012-05-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Arabidopsis thaliana ChloroNEET, a Member of the New NEET Family of Human Proteins, is Involved in Development, Senescence and Iron Metabolism.
To be Published
3MM0
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BU of 3mm0 by Molmil
Crystal structure of chimeric avidin
分子名称: Avidin, Avidin-related protein 4/5
著者Livnah, O, Eisenberg-Domovich, Y, Maatta, J.A.E, Kulomaa, M.S, Hytonen, V.P, Nordlund, H.R.
登録日2010-04-19
公開日2010-10-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Chimeric avidin shows stability against harsh chemical conditions-biochemical analysis and 3D structure.
Biotechnol.Bioeng., 108, 2011
3P63
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Structure of M. laminosus Ferredoxin with a shorter L1,2 loop
分子名称: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin
著者Livnah, O, Nechushtai, R, Eisenberg-Domovich, Y, Michaeli, D.
登録日2010-10-11
公開日2011-02-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Allostery in the ferredoxin protein motif does not involve a conformational switch.
Proc.Natl.Acad.Sci.USA, 108, 2011
7O9Y
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Crystal structure of di-phosphorylated human CLK1 in complex with 4-(1H-indol-3-yl)pyrimidin-2-amine
分子名称: 4-(1~{H}-indol-3-yl)pyrimidin-2-amine, Dual specificity protein kinase CLK1
著者Livnah, O, Domovich, Y, Bracher, F, Aiger, C.
登録日2021-04-18
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Development of novel CLK1 inhibitors as potential drugs for treatment of Chikungunya virus infections
To Be Published
7OA0
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Crystal structure of di-phosphorylated human CLK1 in complex with 5-(6,7-dichloro-1H-indol-3-yl)pyrimidin-4-amine
分子名称: 5-[6,7-bis(chloranyl)-1-methyl-indol-3-yl]pyrimidin-4-amine, Dual specificity protein kinase CLK1
著者Livnah, O, Domovich, Y, Bracher, F, Aiger, C.
登録日2021-04-18
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Development of novel CLK1 inhibitors as potential drugs for treatment of Chikungunya virus infections
To Be Published
1Y55
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Crystal structure of the C122S mutant of E. Coli expressed avidin related protein 4 (AVR4)-biotin complex
分子名称: Avidin-related protein 4/5, BIOTIN, FORMIC ACID
著者Eisenberg-Domovich, Y, Hytonen, V.P, Wilchek, M, Bayer, E.A, Kulomaa, M.S, Livnah, O.
登録日2004-12-02
公開日2005-05-24
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability.
Acta Crystallogr.,Sect.D, 61, 2005
1Y52
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structure of insect cell (Baculovirus) expressed AVR4 (C122S)-biotin complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin-related protein 4/5, BIOTIN
著者Eisenberg-Domovich, Y, Hytonen, V.P, Wilchek, M, Bayer, E.A, Kulomaa, M.S, Livnah, O.
登録日2004-12-02
公開日2005-05-24
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability.
Acta Crystallogr.,Sect.D, 61, 2005
1Y53
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Crystal structure of bacterial expressed avidin related protein 4 (AVR4) C122S
分子名称: Avidin-related protein 4/5, FORMIC ACID
著者Eisenberg-Domovich, Y, Hytonen, V.P, Wilchek, M, Bayer, E.A, Kulomaa, M.S, Livnah, O.
登録日2004-12-02
公開日2005-05-24
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability.
Acta Crystallogr.,Sect.D, 61, 2005
2OFA
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Crystal structure of apo AVR4 (R112L,C122S)
分子名称: Avidin-related protein 4/5, FORMIC ACID
著者Livnah, O, Hayouka, R, Eisenberg-Domovich, Y.
登録日2007-01-03
公開日2007-12-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester.
Acta Crystallogr.,Sect.D, 64, 2008
2OF9
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Crystal structure of apo AVR4 (D39A/C122S)
分子名称: Avidin-related protein 4/5, FORMIC ACID
著者Livnah, O, Hayouka, R, Eisenberg-Domovich, Y.
登録日2007-01-03
公開日2007-12-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester.
Acta Crystallogr.,Sect.D, 64, 2008
2OF8
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Crystal structure of AVR4 (D39A/C122S)-BNA complex
分子名称: 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Avidin-related protein 4/5, FORMIC ACID
著者Livnah, O, Hayouka, R, Eisenberg-Domovich, Y.
登録日2007-01-03
公開日2007-12-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester.
Acta Crystallogr.,Sect.D, 64, 2008
2OFB
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Crystal structure of AVR4 (R112L/C122S)-BNA complex
分子名称: 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Avidin-related protein 4/5, FORMIC ACID
著者Livnah, O, Hayouka, R, Eisenberg-Domovich, Y.
登録日2007-01-03
公開日2007-12-25
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Critical importance of loop conformation to avidin-enhanced hydrolysis of an active biotin ester.
Acta Crystallogr.,Sect.D, 64, 2008
4E6A
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p38a-PIA23 complex
分子名称: (2S)-2-methoxy-3-(octadecyloxy)propyl (1R,2R,3R,4S,6S)-2,3,4-trihydroxy-6-(2-methylpropoxy)cyclohexyl hydrogen (S)-phosphate, Mitogen-activated protein kinase 14
著者Livnah, O, Tzarum, N, Eisenberg-Domovich, Y.
登録日2012-03-15
公開日2012-10-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Lipid Molecules Induce p38 alpha Activation via a Novel Molecular Switch.
J.Mol.Biol., 424, 2012
4E5B
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Structure of p38a MAP kinase without BOG
分子名称: Mitogen-activated protein kinase 14
著者Livnah, O, Eisenberg-Domovich, Y, Tzarum, N.
登録日2012-03-14
公開日2012-10-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Lipid Molecules Induce p38 alpha Activation via a Novel Molecular Switch.
J.Mol.Biol., 424, 2012

 

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