3DU0
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![BU of 3du0 by Molmil](/molmil-images/mine/3du0) | E. coli dihydrodipicolinate synthase with first substrate, pyruvate, bound in active site | Descriptor: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ... | Authors: | Dobson, R.C.J, Devenish, S.R.A, Gerrard, J.A, Jameson, G.B. | Deposit date: | 2008-07-16 | Release date: | 2008-11-18 | Last modified: | 2019-12-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The high-resolution structure of dihydrodipicolinate synthase from Escherichia coli bound to its first substrate, pyruvate. Acta Crystallogr.,Sect.F, 64, 2008
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3IRD
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3I7R
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![BU of 3i7r by Molmil](/molmil-images/mine/3i7r) | Dihydrodipicolinate synthase - K161R | Descriptor: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | Deposit date: | 2009-07-08 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie, 92, 2010
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3I7S
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![BU of 3i7s by Molmil](/molmil-images/mine/3i7s) | Dihydrodipicolinate synthase mutant - K161A - with the substrate pyruvate bound in the active site. | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | Deposit date: | 2009-07-08 | Release date: | 2010-04-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie, 92, 2010
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3C0J
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![BU of 3c0j by Molmil](/molmil-images/mine/3c0j) | |
3DAQ
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![BU of 3daq by Molmil](/molmil-images/mine/3daq) | Crystal structure of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus | Descriptor: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL | Authors: | Dobson, R.C.J, Burgess, B.R, Jameson, G.B, Gerrard, J.A, Parker, M.W, Perugini, M.A. | Deposit date: | 2008-05-29 | Release date: | 2008-08-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure and evolution of a novel dimeric enzyme from a clinically-important bacterial pathogen. J.Biol.Chem., 2008
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1S5T
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![BU of 1s5t by Molmil](/molmil-images/mine/1s5t) | |
1S5V
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![BU of 1s5v by Molmil](/molmil-images/mine/1s5v) | |
1S5W
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![BU of 1s5w by Molmil](/molmil-images/mine/1s5w) | |
2PUR
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![BU of 2pur by Molmil](/molmil-images/mine/2pur) | Structure of dihydrodipicolinate synthase mutant Thr44Ser at 1.7 A. | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A. | Deposit date: | 2007-05-09 | Release date: | 2008-05-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis. Biochimie, 91, 2009
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3QGU
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![BU of 3qgu by Molmil](/molmil-images/mine/3qgu) | L,L-Diaminopimelate aminotransferase from Chlamydomonas reinhardtii | Descriptor: | AZIDE ION, GLYCEROL, LL-diaminopimelate aminotransferase, ... | Authors: | Dobson, R.C.J, Giron, I, Hudson, A.O. | Deposit date: | 2011-01-25 | Release date: | 2011-06-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | L,L-Diaminopimelate Aminotransferase from Chlamydomonas reinhardtii: A Target for Algaecide Development Plos One, 6, 2011
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3I7Q
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![BU of 3i7q by Molmil](/molmil-images/mine/3i7q) | Dihydrodipicolinate synthase mutant - K161A | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | Deposit date: | 2009-07-08 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie, 92, 2010
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1YXC
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![BU of 1yxc by Molmil](/molmil-images/mine/1yxc) | Structure of E. coli dihydrodipicolinate synthase to 1.9 A | Descriptor: | CHLORIDE ION, POTASSIUM ION, dihydrodipicolinate synthase | Authors: | Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. | Deposit date: | 2005-02-20 | Release date: | 2005-08-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance. Acta Crystallogr.,Sect.D, 61, 2005
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1YXD
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![BU of 1yxd by Molmil](/molmil-images/mine/1yxd) | Structure of E. coli dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine to 2.0 A | Descriptor: | CHLORIDE ION, LYSINE, POTASSIUM ION, ... | Authors: | Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. | Deposit date: | 2005-02-20 | Release date: | 2005-08-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance. Acta Crystallogr.,Sect.D, 61, 2005
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7T3E
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![BU of 7t3e by Molmil](/molmil-images/mine/7t3e) | Structure of the sialic acid bound Tripartite ATP-independent Periplasmic (TRAP) periplasmic component SiaP from Photobacterium profundum | Descriptor: | N-acetyl-beta-neuraminic acid, SULFATE ION, TRAP-type C4-dicarboxylate transport system, ... | Authors: | Davies, J.S, Currie, M.J, North, R.A, Dobson, R.C.J. | Deposit date: | 2021-12-07 | Release date: | 2022-12-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.04 Å) | Cite: | Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter. Nat Commun, 14, 2023
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8B01
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![BU of 8b01 by Molmil](/molmil-images/mine/8b01) | Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Photobacterium profundum in a nanodisc | Descriptor: | DECANE, DOCOSANE, HEXANE, ... | Authors: | Davies, J.S, North, R.A, Dobson, R.C.J. | Deposit date: | 2022-09-06 | Release date: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter. Nat Commun, 14, 2023
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8UUB
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![BU of 8uub by Molmil](/molmil-images/mine/8uub) | Structure of hypothiocyanous acid reductase (Har) from Streptococcus pneumoniae | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, Oxidoreductase, ... | Authors: | Shearer, H.L, Currie, M.J, Dickerhof, N, Dobson, R.C.J. | Deposit date: | 2023-10-31 | Release date: | 2024-04-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Hypothiocyanous acid reductase is critical for host colonization and infection by Streptococcus pneumoniae. J.Biol.Chem., 300, 2024
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8GEK
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![BU of 8gek by Molmil](/molmil-images/mine/8gek) | Dihydrodipicolinate synthase with pyruvate from Candidatus Liberibacter solanacearum | Descriptor: | 4-hydroxy-tetrahydrodipicolinate synthase | Authors: | Gilkes, J.M, Frampton, R.A, Board, A, Sheen, C.R, Smith, G.R, Dobson, R.C.J. | Deposit date: | 2023-03-06 | Release date: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Dihydrodipicolinate synthase with pyruvate from the plant pathogen, Candidatus Liberibacter solanacearum To Be Published
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6H4E
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![BU of 6h4e by Molmil](/molmil-images/mine/6h4e) | Proteus mirabilis N-acetylneuraminate lyase | Descriptor: | Putative N-acetylneuraminate lyase, SULFATE ION | Authors: | North, R.A, Garcia-Bonete, M.J, Goyal, P, Katona, G, Dobson, R.C.J, Friemann, R. | Deposit date: | 2018-07-21 | Release date: | 2019-06-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.561 Å) | Cite: | The structure of Proteus mirabilis N-acetylneuraminate lyase reveals an intermolecular disulphide bond To Be Published
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8THJ
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![BU of 8thj by Molmil](/molmil-images/mine/8thj) | Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (antiparallel dimer) | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ... | Authors: | Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A. | Deposit date: | 2023-07-16 | Release date: | 2023-11-22 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (2.99 Å) | Cite: | Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter. Elife, 12, 2024
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8THI
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![BU of 8thi by Molmil](/molmil-images/mine/8thi) | Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (parallel dimer) | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, SODIUM ION, Sialic acid TRAP transporter permease protein SiaT | Authors: | Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A. | Deposit date: | 2023-07-16 | Release date: | 2023-11-22 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.36 Å) | Cite: | Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter. Elife, 12, 2024
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6Q26
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4OY5
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![BU of 4oy5 by Molmil](/molmil-images/mine/4oy5) | 0.89 Angstrom resolution crystal structure of (Gly-Pro-Hyp)10 | Descriptor: | Collagen | Authors: | Suzuki, H, Mahapatra, D, Steel, P.J, Dyer, J, Dobson, R.C.J, Gerrard, J.A, Valery, C. | Deposit date: | 2014-02-10 | Release date: | 2015-03-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (0.89 Å) | Cite: | Sub-angstrom structure of the collagen model peptide (GPO)10 shows a hydrated triple helix with pitch variation and two proline ring conformations To Be Published
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7QHA
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![BU of 7qha by Molmil](/molmil-images/mine/7qha) | Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Photobacterium profundum in amphipol | Descriptor: | Megabody c7HopQ, Putative TRAP-type C4-dicarboxylate transport system, large permease component, ... | Authors: | North, R.A, Davies, J.S, Morado, D, Dobson, R.C.J. | Deposit date: | 2021-12-11 | Release date: | 2022-12-21 | Last modified: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter. Nat Commun, 14, 2023
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4HNN
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