8THJ
 
 | | Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (antiparallel dimer) | | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ... | | Authors: | Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A. | | Deposit date: | 2023-07-16 | | Release date: | 2023-11-22 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (2.99 Å) | | Cite: | Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
Elife, 12, 2024
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8UUB
 | | Structure of hypothiocyanous acid reductase (Har) from Streptococcus pneumoniae | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, Oxidoreductase, ... | | Authors: | Shearer, H.L, Currie, M.J, Dickerhof, N, Dobson, R.C.J. | | Deposit date: | 2023-10-31 | | Release date: | 2024-04-17 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Hypothiocyanous acid reductase is critical for host colonization and infection by Streptococcus pneumoniae.
J.Biol.Chem., 300, 2024
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7RUM
 | | Endolysin from Escherichia coli O157:H7 phage FTEbC1, LysT84 | | Descriptor: | Endolysin, GLYCEROL | | Authors: | Love, M.J, Billington, C, Dobson, R.C.J. | | Deposit date: | 2021-08-17 | | Release date: | 2022-02-09 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.99 Å) | | Cite: | The structure and function of modular Escherichia coli O157:H7 bacteriophage FTBEc1 endolysin, LysT84: defining a new endolysin catalytic subfamily.
Biochem.J., 479, 2022
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5KZD
 | | N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus with bound sialic acid alditol | | Descriptor: | (2~{S},4~{S},5~{R},6~{R},7~{S},8~{R})-5-acetamido-2,4,6,7,8,9-hexakis(oxidanyl)nonanoic acid, N-acetylneuraminate lyase | | Authors: | North, R.A, Watson, A.J.A, Pearce, F.G, Muscroft-Taylor, A.C, Friemann, R, Fairbanks, A.J, Dobson, R.C.J. | | Deposit date: | 2016-07-25 | | Release date: | 2017-01-11 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.334 Å) | | Cite: | Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus.
FEBS Lett., 590, 2016
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5KZE
 | | N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus | | Descriptor: | GLYCEROL, N-acetylneuraminate lyase, SULFATE ION | | Authors: | North, R.A, Watson, A.J.A, Pearce, F.G, Muscroft-Taylor, A.C, Friemann, R, Fairbanks, A.J, Dobson, R.C.J. | | Deposit date: | 2016-07-25 | | Release date: | 2017-01-11 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus.
FEBS Lett., 590, 2016
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4C1L
 | | Crystal structure of pyrococcus furiosus 3-deoxy-D-arabino- heptulosonate 7-phosphate synthase I181D interface mutant | | Descriptor: | 2-dehydro-3-deoxyphosphoheptonate aldolase, CHLORIDE ION, MANGANESE (II) ION, ... | | Authors: | Nazmi, A.R, Schofield, L.R, Dobson, R.C.J, Jameson, G.B, Parker, E.J. | | Deposit date: | 2013-08-13 | | Release date: | 2013-11-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Destabilization of the homotetrameric assembly of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from the hyperthermophile Pyrococcus furiosus enhances enzymatic activity.
J. Mol. Biol., 426, 2014
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4OY5
 | | 0.89 Angstrom resolution crystal structure of (Gly-Pro-Hyp)10 | | Descriptor: | Collagen | | Authors: | Suzuki, H, Mahapatra, D, Steel, P.J, Dyer, J, Dobson, R.C.J, Gerrard, J.A, Valery, C. | | Deposit date: | 2014-02-10 | | Release date: | 2015-03-04 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (0.89 Å) | | Cite: | Sub-angstrom structure of the collagen model peptide (GPO)10 shows a hydrated triple helix with pitch variation and two proline ring conformations
To Be Published
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4C1K
 | | Crystal structure of pyrococcus furiosus 3-deoxy-D-arabino- heptulosonate 7-phosphate synthase | | Descriptor: | 2-DEHYDRO-3-DEOXYPHOSPHOHEPTONATE ALDOLASE, CADMIUM ION, CARBONATE ION, ... | | Authors: | Nazmi, A.R, Schofield, L.R, Dobson, R.C.J, Jameson, G.B, Parker, E.J. | | Deposit date: | 2013-08-13 | | Release date: | 2013-11-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Destabilization of the Homotetrameric Assembly of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase from the Hyperthermophile Pyrococcus Furiosus Enhances Enzymatic Activity
J.Mol.Biol., 426, 2014
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8EDQ
 | | E. coli pyruvate kinase (PykF) I264F | | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Pyruvate kinase, SULFATE ION | | Authors: | Donovan, K.A, Coombes, D, Dobson, R.C.J, Cooper, T.F. | | Deposit date: | 2022-09-05 | | Release date: | 2022-11-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.88 Å) | | Cite: | Beneficial mutations occurring in E. coli pyruvate kinase afford new allosteric mechanisms leading to faster resumption of growth
To Be Published
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8EDT
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8EDS
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8EDR
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8EQ0
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8EQ1
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8EQ3
 | | Escherichia coli pyruvate kinase A301T | | Descriptor: | IMIDAZOLE, MALONATE ION, Pyruvate kinase, ... | | Authors: | Donovan, K.A, Coombes, D, Dobson, R.C.J, Cooper, T.F. | | Deposit date: | 2022-10-07 | | Release date: | 2023-01-18 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Beneficial mutations occurring in E. coli pyruvate kinase afford new allosteric mechanisms leading to faster resumption of growth
To Be Published
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8EU4
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6Q26
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6Q27
 | | N-acetylmannosamine kinase with N-acetylmannosamine from Staphylococcus aureus | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-mannopyranose, Glucokinase | | Authors: | Coombes, D, Horne, C.R, Davies, J.S, Dobson, R.C.J. | | Deposit date: | 2019-08-07 | | Release date: | 2020-01-22 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The basis for non-canonical ROK family function in theN-acetylmannosamine kinase from the pathogenStaphylococcus aureus.
J.Biol.Chem., 295, 2020
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6Q28
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6N2A
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3A5F
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4WAA
 | | Crystal structure of Nix LIR-fused human LC3B_2-119 | | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B | | Authors: | Suzuki, H, Ravichandran, A.C, Dobson, R.C.J, Novak, I, Wakatsuki, S. | | Deposit date: | 2014-08-29 | | Release date: | 2015-09-09 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins.
Sci Rep, 7, 2017
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3PB0
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3PB2
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3WAO
 | | Crystal structure of Atg13 LIR-fused human LC3B_2-119 | | Descriptor: | Autophagy-related protein 13, Microtubule-associated proteins 1A/1B light chain 3B | | Authors: | Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S. | | Deposit date: | 2013-05-06 | | Release date: | 2013-12-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.
Structure, 22, 2014
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