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PDB: 97 results

8EQ1
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BU of 8eq1 by Molmil
Escherichia coli pyruvate kinase D127N
Descriptor: Pyruvate kinase, SULFATE ION
Authors:Donovan, K.A, Coombes, D, Dobson, R.C.J, Cooper, T.F.
Deposit date:2022-10-07
Release date:2023-01-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Beneficial mutations occurring in E. coli pyruvate kinase afford new allosteric mechanisms leading to faster resumption of growth
To Be Published
8EQ3
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BU of 8eq3 by Molmil
Escherichia coli pyruvate kinase A301T
Descriptor: IMIDAZOLE, MALONATE ION, Pyruvate kinase, ...
Authors:Donovan, K.A, Coombes, D, Dobson, R.C.J, Cooper, T.F.
Deposit date:2022-10-07
Release date:2023-01-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Beneficial mutations occurring in E. coli pyruvate kinase afford new allosteric mechanisms leading to faster resumption of growth
To Be Published
8EU4
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BU of 8eu4 by Molmil
Escherichia coli pyruvate kinase A301S
Descriptor: Pyruvate kinase, SULFATE ION
Authors:Donovan, K.A, Coombes, D, Dobson, R.C.J, Cooper, T.F.
Deposit date:2022-10-18
Release date:2023-01-18
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Beneficial mutations occurring in E. coli pyruvate kinase afford new allosteric mechanisms leading to faster resumption of growth
To Be Published
6N2A
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BU of 6n2a by Molmil
Meso-Diaminopimelate Decarboxylase from Arabidopsis thaliana (Isoform 1)
Descriptor: Diaminopimelate decarboxylase 1, chloroplastic, LYSINE, ...
Authors:Crowther, J.M, Dobson, R.C.J.
Deposit date:2018-11-12
Release date:2019-04-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Active site gating provides stereochemical control for meso-diaminopimelate decarboxylase
To Be Published
6N2F
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BU of 6n2f by Molmil
Meso-Diaminopimelate Decarboxylase from Arabidopsis thaliana (Isoform 2)
Descriptor: Diaminopimelate decarboxylase 2, chloroplastic, LYSINE, ...
Authors:Crowther, J.M, Dobson, R.C.J.
Deposit date:2018-11-12
Release date:2019-04-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Active site gating provides stereochemical control for meso-diaminopimelate decarboxylase
To Be Published
3A5F
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BU of 3a5f by Molmil
High-resolution structure of DHDPS from Clostridium botulinum in complex with pyruvate
Descriptor: Dihydrodipicolinate synthase, GLYCEROL
Authors:Atkinson, S.C, Dobson, R.C.J, Perugini, M.A.
Deposit date:2009-08-06
Release date:2010-06-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:The high resolution structure of DHDPS from Clostridium botulinum
To be Published
3PB0
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BU of 3pb0 by Molmil
Characterisation of the first monomeric dihydrodipicolinate synthase variant reveals evolutionary insights
Descriptor: Dihydrodipicolinate synthase, SULFATE ION
Authors:Pearce, F.G, Dobson, R.C.J, Jameson, G.B.
Deposit date:2010-10-19
Release date:2011-11-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization.
Biochim.Biophys.Acta, 1814, 2011
3PB2
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BU of 3pb2 by Molmil
Characterisation of the first monomeric dihydrodipicolinate synthase variant reveals evolutionary insights
Descriptor: Dihydrodipicolinate synthase, GLYCEROL
Authors:Pearce, F.G, Dobson, R.C.J, Jameson, G.B.
Deposit date:2010-10-20
Release date:2011-11-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization.
Biochim.Biophys.Acta, 1814, 2011
3WAO
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BU of 3wao by Molmil
Crystal structure of Atg13 LIR-fused human LC3B_2-119
Descriptor: Autophagy-related protein 13, Microtubule-associated proteins 1A/1B light chain 3B
Authors:Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S.
Deposit date:2013-05-06
Release date:2013-12-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.
Structure, 22, 2014
3WAL
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BU of 3wal by Molmil
Crystal structure of human LC3A_2-121
Descriptor: D-MALATE, Microtubule-associated proteins 1A/1B light chain 3A
Authors:Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S.
Deposit date:2013-05-06
Release date:2013-12-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.
Structure, 22, 2014
3WAN
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BU of 3wan by Molmil
Crystal structure of Atg13 LIR-fused human LC3A_2-121
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Autophagy-related protein 13, Microtubule-associated proteins 1A/1B light chain 3A
Authors:Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S.
Deposit date:2013-05-06
Release date:2013-12-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.
Structure, 22, 2014
3WAM
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BU of 3wam by Molmil
Crystal structure of human LC3C_8-125
Descriptor: CITRIC ACID, Microtubule-associated proteins 1A/1B light chain 3C
Authors:Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S.
Deposit date:2013-05-06
Release date:2013-12-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.
Structure, 22, 2014
3WAP
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BU of 3wap by Molmil
Crystal structure of Atg13 LIR-fused human LC3C_8-125
Descriptor: Autophagy-related protein 13, Microtubule-associated proteins 1A/1B light chain 3C
Authors:Suzuki, H, Tabata, K, Morita, E, Kawasaki, M, Kato, R, Dobson, R.C.J, Yoshimori, T, Wakatsuki, S.
Deposit date:2013-05-06
Release date:2013-12-25
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.
Structure, 22, 2014
4WAA
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BU of 4waa by Molmil
Crystal structure of Nix LIR-fused human LC3B_2-119
Descriptor: Microtubule-associated proteins 1A/1B light chain 3B
Authors:Suzuki, H, Ravichandran, A.C, Dobson, R.C.J, Novak, I, Wakatsuki, S.
Deposit date:2014-08-29
Release date:2015-09-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Phosphorylation of the mitochondrial autophagy receptor Nix enhances its interaction with LC3 proteins.
Sci Rep, 7, 2017
7LOY
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BU of 7loy by Molmil
Dihydrodipicolinate synthase with pyruvate from Candidatus Liberibacter solanacearum
Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase
Authors:Gilkes, J.M, Frampton, R.A, Board, A, Sheen, C.R, Smith, G.R, Dobson, R.C.J.
Deposit date:2021-02-11
Release date:2021-03-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Dihydrodipicolinate synthase with pyruvate from the plant pathogen, Candidatus Liberibacter solanacearum
To Be Published
3PG8
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BU of 3pg8 by Molmil
Truncated form of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Thermotoga maritima
Descriptor: AZIDE ION, GLYCEROL, Phospho-2-dehydro-3-deoxyheptonate aldolase
Authors:Cross, P.J, Dobson, R.C.J, Patchett, M.L, Parker, E.J.
Deposit date:2010-10-31
Release date:2011-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis
J.Biol.Chem., 286, 2011
3PG9
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BU of 3pg9 by Molmil
Thermotoga maritima DAH7P synthase in complex with inhibitor
Descriptor: AZIDE ION, CHLORIDE ION, NITRATE ION, ...
Authors:Cross, P.J, Dobson, R.C.J, Patchett, M.L, Parker, E.J.
Deposit date:2010-10-31
Release date:2011-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Tyrosine latching of a regulatory gate affords allosteric control of aromatic amino acid biosynthesis
J.Biol.Chem., 286, 2011
4EOU
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BU of 4eou by Molmil
Crystal structure of E. coli dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
Descriptor: Dihydrodipicolinate synthase, GLYCEROL, POTASSIUM ION
Authors:Boughton, B.A, Dobson, R.C.J, Hutton, C.A.
Deposit date:2012-04-15
Release date:2012-04-25
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of dihydrodipicolinate synthase from Escherichia coli with bound pyruvate and succinic acid semialdehyde: Unambiguous resolution of the stereochemistry of the condensation product.
Proteins, 80, 2012
4HNN
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BU of 4hnn by Molmil
Dihydrodipicolinate Synthase from the common grapevine with pyruvate and lysine
Descriptor: Dihydrodipicolinate synthase, LYSINE
Authors:Atkinson, S.C, Dobson, R.C.J, Perugini, M.A.
Deposit date:2012-10-19
Release date:2013-09-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural, kinetic and computational investigation of Vitis vinifera DHDPS reveals new insight into the mechanism of lysine-mediated allosteric inhibition.
Plant Mol.Biol., 81, 2013
7LVL
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BU of 7lvl by Molmil
Dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine from Candidatus Liberibacter solanacearum
Descriptor: 4-hydroxy-tetrahydrodipicolinate synthase, LYSINE
Authors:Gilkes, J.M, Frampton, R.A, Board, A.J, Sheen, C.R, Smith, G.R, Dobson, R.C.J.D.
Deposit date:2021-02-25
Release date:2021-03-10
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine from Candidatus Liberibacter solanacearum
To Be Published
7MJF
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BU of 7mjf by Molmil
Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
Descriptor: (4R)-4-oxidanyl-2-oxidanylidene-heptanedioic acid, (4S)-4-hydroxy-2-oxoheptanedioic acid, 4-hydroxy-tetrahydrodipicolinate synthase
Authors:Gilkes, J, Frampton, R.A, Board, A.J, Sheen, C.R, Smith, G.R, Dobson, R.C.J.
Deposit date:2021-04-20
Release date:2021-07-14
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
To Be Published
7M5I
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BU of 7m5i by Molmil
Endolysin from Escherichia coli O157:H7 phage FAHEc1
Descriptor: Endolysin, PHOSPHATE ION
Authors:Love, M.J, Coombes, D, Billington, C, Dobson, R.C.J.
Deposit date:2021-03-24
Release date:2021-08-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:The Molecular Basis for Escherichia coli O157:H7 Phage FAHEc1 Endolysin Function and Protein Engineering to Increase Thermal Stability.
Viruses, 13, 2021
7MFS
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BU of 7mfs by Molmil
N-Acetylmannosamine-6-phosphate 2-epimerase from Staphylococcus aureus (strain MRSA USA300) with substrate and product bound
Descriptor: CHLORIDE ION, N-acetyl-D-glucosamine-6-phosphate, N-acetylmannosamine-6-phosphate, ...
Authors:Currie, M.J, Dobson, R.C.J.
Deposit date:2021-04-11
Release date:2022-04-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization.
J.Biol.Chem., 297, 2021
7MFN
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BU of 7mfn by Molmil
N-Acetylmannosamine-6-phosphate 2-epimerase E180A from Staphylococcus aureus (strain MRSA USA300)
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CITRIC ACID, ...
Authors:Currie, M.J, Dobson, R.C.J.
Deposit date:2021-04-10
Release date:2022-04-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization.
J.Biol.Chem., 297, 2021
7MQT
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BU of 7mqt by Molmil
N-Acetylmannosamine-6-phosphate 2-epimerase from Staphylococcus aureus (strain MRSA USA300) with 5-deoxy substrate bound
Descriptor: 2-acetamido-2,5-dideoxy-6-O-phosphono-D-lyxo-hexose, CHLORIDE ION, CITRIC ACID, ...
Authors:Currie, M.J, Dobson, R.C.J.
Deposit date:2021-05-06
Release date:2022-04-20
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization.
J.Biol.Chem., 297, 2021

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