4ZIN
| Genetically encoded Phenyl Azide Photochemistry Drive Positive and Negative Functional Modulation of a Red Fluorescent Protein | 分子名称: | 1,2-ETHANEDIOL, MCherry fluorescent protein, SULFATE ION | 著者 | Reddington, S.C, Driezis, S, Hartley, A.M, Watson, P.D, Rizkallah, P.J, Jones, D.D. | 登録日 | 2015-04-28 | 公開日 | 2015-09-16 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Genetically encoded phenyl azide photochemistry drives positive and negative functional modulation of a red fluorescent protein Rsc Adv, 5, 2015
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4ZIO
| Irradiated state of mCherry143azF | 分子名称: | SULFATE ION, mCherry | 著者 | Reddington, S.C, Driezis, S, Hartley, A.M, Watson, P.D, Rizkallah, P.J, Jones, D.D. | 登録日 | 2015-04-28 | 公開日 | 2015-09-16 | 最終更新日 | 2018-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Genetically encoded phenyl azide photochemistry drives positive and negative functional modulation of a red fluorescent protein Rsc Adv, 5, 2015
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4J88
| Dark-state structure of sfGFP containing the unnatural amino acid p-azido-phenylalanine at residue 66 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Green fluorescent protein, ... | 著者 | Reddington, S.C, Jones, D.D, Rizkallah, P.J, Tippmann, E.M. | 登録日 | 2013-02-14 | 公開日 | 2013-06-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Different Photochemical Events of a Genetically Encoded Phenyl Azide Define and Modulate GFP Fluorescence. Angew.Chem.Int.Ed.Engl., 52, 2013
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4J8A
| Irradiated-state structure of sfGFP containing the unnatural amino acid p-azido-phenylalanine at residue 145 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Green fluorescent protein, ... | 著者 | Reddington, S.C, Jones, D.D, Rizkallah, P.J, Tippmann, E.M. | 登録日 | 2013-02-14 | 公開日 | 2013-05-15 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Different Photochemical Events of a Genetically Encoded Phenyl Azide Define and Modulate GFP Fluorescence. Angew.Chem.Int.Ed.Engl., 52, 2013
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4J89
| Different photochemical events of a genetically encoded aryl azide define and modulate GFP fluorescence | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Green fluorescent protein, ... | 著者 | Reddington, S.C, Jones, D.D, Rizkallah, P.J, Tippmann, E.M. | 登録日 | 2013-02-14 | 公開日 | 2013-06-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Different Photochemical Events of a Genetically Encoded Phenyl Azide Define and Modulate GFP Fluorescence. Angew.Chem.Int.Ed.Engl., 52, 2013
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6N3L
| Identification of novel, potent and selective GCN2 inhibitors as first-in-class anti-tumor agents | 分子名称: | N-{6-[(1-methyl-2-{[4-(trifluoromethyl)phenyl]amino}-1H-benzimidazol-5-yl)oxy]pyrimidin-4-yl}cyclopropanecarboxamide, eIF-2-alpha kinase GCN2,eIF-2-alpha kinase GCN2 | 著者 | Hoffman, I.D, Fujimoto, J, Kurasawa, O, Takagi, T, Klein, M.G, Kefala, G, Ding, S.C, Cary, D.R, Mizojiri, R. | 登録日 | 2018-11-15 | 公開日 | 2019-10-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode. Acs Med.Chem.Lett., 10, 2019
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6N3N
| Identification of novel, potent and selective GCN2 inhibitors as first-in-class anti-tumor agents | 分子名称: | N-{3-[(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl}-2,5-dichloro-3-(hydroxymethyl)benzene-1-sulfonamide, eIF-2-alpha kinase GCN2,eIF-2-alpha kinase GCN2 | 著者 | Hoffman, I.D, Fujimoto, J, Kurasawa, O, Takagi, T, Klein, M.G, Kefala, G, Ding, S.C, Cary, D.R, Mizojiri, R. | 登録日 | 2018-11-15 | 公開日 | 2019-10-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode. Acs Med.Chem.Lett., 10, 2019
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6N3O
| Identification of novel, potent and selective GCN2 inhibitors as first-in-class anti-tumor agents | 分子名称: | N-{3-[(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl}-5-chloro-2-methoxypyridine-3-sulfonamide, eIF-2-alpha kinase GCN2 | 著者 | Hoffman, I.D, Fujimoto, J, Kurasawa, O, Takagi, T, Klein, M.G, Kefala, G, Ding, S.C, Cary, D.R, Mizojiri, R. | 登録日 | 2018-11-15 | 公開日 | 2019-10-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode. Acs Med.Chem.Lett., 10, 2019
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5BT0
| Switching GFP fluorescence using genetically encoded phenyl azide chemistry through two different non-native post-translational modifications routes at the same position. | 分子名称: | Green fluorescent protein, SULFATE ION | 著者 | Hartley, A.M, Worthy, H.L, Reddington, S.C, Rizkallah, P.J, Jones, D.D. | 登録日 | 2015-06-02 | 公開日 | 2016-07-13 | 最終更新日 | 2017-05-10 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Molecular basis for functional switching of GFP by two disparate non-native post-translational modifications of a phenyl azide reaction handle. Chem Sci, 7, 2016
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5BTT
| Switching GFP fluorescence using genetically encoded phenyl azide chemistry through two different non-native post-translational modifications routes at the same position. | 分子名称: | GLYCEROL, Green fluorescent protein, SULFATE ION | 著者 | Hartley, A.M, Worthy, H.L, Reddington, S.C, Rizkallah, P.J, Jones, D.D. | 登録日 | 2015-06-03 | 公開日 | 2016-07-13 | 最終更新日 | 2017-05-10 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Molecular basis for functional switching of GFP by two disparate non-native post-translational modifications of a phenyl azide reaction handle. Chem Sci, 7, 2016
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