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PDB: 10 件

4ZIN
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BU of 4zin by Molmil
Genetically encoded Phenyl Azide Photochemistry Drive Positive and Negative Functional Modulation of a Red Fluorescent Protein
分子名称: 1,2-ETHANEDIOL, MCherry fluorescent protein, SULFATE ION
著者Reddington, S.C, Driezis, S, Hartley, A.M, Watson, P.D, Rizkallah, P.J, Jones, D.D.
登録日2015-04-28
公開日2015-09-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Genetically encoded phenyl azide photochemistry drives positive and negative functional modulation of a red fluorescent protein
Rsc Adv, 5, 2015
4ZIO
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BU of 4zio by Molmil
Irradiated state of mCherry143azF
分子名称: SULFATE ION, mCherry
著者Reddington, S.C, Driezis, S, Hartley, A.M, Watson, P.D, Rizkallah, P.J, Jones, D.D.
登録日2015-04-28
公開日2015-09-16
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Genetically encoded phenyl azide photochemistry drives positive and negative functional modulation of a red fluorescent protein
Rsc Adv, 5, 2015
4J88
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BU of 4j88 by Molmil
Dark-state structure of sfGFP containing the unnatural amino acid p-azido-phenylalanine at residue 66
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Green fluorescent protein, ...
著者Reddington, S.C, Jones, D.D, Rizkallah, P.J, Tippmann, E.M.
登録日2013-02-14
公開日2013-06-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Different Photochemical Events of a Genetically Encoded Phenyl Azide Define and Modulate GFP Fluorescence.
Angew.Chem.Int.Ed.Engl., 52, 2013
4J8A
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BU of 4j8a by Molmil
Irradiated-state structure of sfGFP containing the unnatural amino acid p-azido-phenylalanine at residue 145
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Green fluorescent protein, ...
著者Reddington, S.C, Jones, D.D, Rizkallah, P.J, Tippmann, E.M.
登録日2013-02-14
公開日2013-05-15
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Different Photochemical Events of a Genetically Encoded Phenyl Azide Define and Modulate GFP Fluorescence.
Angew.Chem.Int.Ed.Engl., 52, 2013
4J89
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BU of 4j89 by Molmil
Different photochemical events of a genetically encoded aryl azide define and modulate GFP fluorescence
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Green fluorescent protein, ...
著者Reddington, S.C, Jones, D.D, Rizkallah, P.J, Tippmann, E.M.
登録日2013-02-14
公開日2013-06-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Different Photochemical Events of a Genetically Encoded Phenyl Azide Define and Modulate GFP Fluorescence.
Angew.Chem.Int.Ed.Engl., 52, 2013
6N3L
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BU of 6n3l by Molmil
Identification of novel, potent and selective GCN2 inhibitors as first-in-class anti-tumor agents
分子名称: N-{6-[(1-methyl-2-{[4-(trifluoromethyl)phenyl]amino}-1H-benzimidazol-5-yl)oxy]pyrimidin-4-yl}cyclopropanecarboxamide, eIF-2-alpha kinase GCN2,eIF-2-alpha kinase GCN2
著者Hoffman, I.D, Fujimoto, J, Kurasawa, O, Takagi, T, Klein, M.G, Kefala, G, Ding, S.C, Cary, D.R, Mizojiri, R.
登録日2018-11-15
公開日2019-10-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode.
Acs Med.Chem.Lett., 10, 2019
6N3N
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BU of 6n3n by Molmil
Identification of novel, potent and selective GCN2 inhibitors as first-in-class anti-tumor agents
分子名称: N-{3-[(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl}-2,5-dichloro-3-(hydroxymethyl)benzene-1-sulfonamide, eIF-2-alpha kinase GCN2,eIF-2-alpha kinase GCN2
著者Hoffman, I.D, Fujimoto, J, Kurasawa, O, Takagi, T, Klein, M.G, Kefala, G, Ding, S.C, Cary, D.R, Mizojiri, R.
登録日2018-11-15
公開日2019-10-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode.
Acs Med.Chem.Lett., 10, 2019
6N3O
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BU of 6n3o by Molmil
Identification of novel, potent and selective GCN2 inhibitors as first-in-class anti-tumor agents
分子名称: N-{3-[(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl}-5-chloro-2-methoxypyridine-3-sulfonamide, eIF-2-alpha kinase GCN2
著者Hoffman, I.D, Fujimoto, J, Kurasawa, O, Takagi, T, Klein, M.G, Kefala, G, Ding, S.C, Cary, D.R, Mizojiri, R.
登録日2018-11-15
公開日2019-10-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode.
Acs Med.Chem.Lett., 10, 2019
5BT0
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BU of 5bt0 by Molmil
Switching GFP fluorescence using genetically encoded phenyl azide chemistry through two different non-native post-translational modifications routes at the same position.
分子名称: Green fluorescent protein, SULFATE ION
著者Hartley, A.M, Worthy, H.L, Reddington, S.C, Rizkallah, P.J, Jones, D.D.
登録日2015-06-02
公開日2016-07-13
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Molecular basis for functional switching of GFP by two disparate non-native post-translational modifications of a phenyl azide reaction handle.
Chem Sci, 7, 2016
5BTT
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BU of 5btt by Molmil
Switching GFP fluorescence using genetically encoded phenyl azide chemistry through two different non-native post-translational modifications routes at the same position.
分子名称: GLYCEROL, Green fluorescent protein, SULFATE ION
著者Hartley, A.M, Worthy, H.L, Reddington, S.C, Rizkallah, P.J, Jones, D.D.
登録日2015-06-03
公開日2016-07-13
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Molecular basis for functional switching of GFP by two disparate non-native post-translational modifications of a phenyl azide reaction handle.
Chem Sci, 7, 2016

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件を2024-10-09に公開中

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