5IRC
 
 | | p190A GAP domain complex with RhoA | | Descriptor: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Derewenda, U, Derewenda, Z. | | Deposit date: | 2016-03-12 | | Release date: | 2016-08-17 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.
J.Biol.Chem., 291, 2016
|
|
6TAA
 | | STRUCTURE AND MOLECULAR MODEL REFINEMENT OF ASPERGILLUS ORYZAE (TAKA) ALPHA-AMYLASE: AN APPLICATION OF THE SIMULATED-ANNEALING METHOD | | Descriptor: | ALPHA-AMYLASE, CALCIUM ION | | Authors: | Swift, H.J, Brady, L, Derewenda, Z.S, Dodson, E.J, Turkenburg, J.P, Wilkinson, A.J. | | Deposit date: | 1992-08-21 | | Release date: | 1993-10-31 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure and molecular model refinement of Aspergillus oryzae (TAKA) alpha-amylase: an application of the simulated-annealing method.
Acta Crystallogr.,Sect.B, 47, 1991
|
|
1QVY
 | | Crystal structure of RhoGDI K(199,200)R double mutant | | Descriptor: | Rho GDP-dissociation inhibitor 1, SULFATE ION | | Authors: | Czepas, J, Devedjiev, Y, Krowarsh, D, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2003-08-29 | | Release date: | 2004-02-10 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The impact of Lys-->Arg surface mutations on the crystallization of the globular domain of RhoGDI.
Acta Crystallogr.,Sect.D, 60, 2004
|
|
1R6F
 | | The structure of Yersinia pestis V-antigen, an essential virulence factor and mediator of immunity against plague | | Descriptor: | Virulence-associated V antigen | | Authors: | Derewenda, U, Mateja, A, Devedjiev, Y, Routzahn, K.M, Evdokimov, A.G, Derewenda, Z.S, Waugh, D.S. | | Deposit date: | 2003-10-15 | | Release date: | 2004-03-09 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | The structure of Yersinia pestis V-antigen, an essential virulence factor and mediator of immunity against plague
Structure, 12, 2004
|
|
1R6J
 | | Ultrahigh resolution Crystal Structure of syntenin PDZ2 | | Descriptor: | CHLORIDE ION, Syntenin 1 | | Authors: | Kang, B.S, Devedjiev, Y, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2003-10-15 | | Release date: | 2004-05-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (0.73 Å) | | Cite: | The PDZ2 domain of syntenin at ultra-high resolution: bridging the gap between small molecule and macromolecular crystal chemistry
J.Mol.Biol., 338, 2004
|
|
3HD0
 | | Crystal structure of Tm1865, an Endonuclease V from Thermotoga Maritima | | Descriptor: | Endonuclease V | | Authors: | Utepbergenov, D, Cooper, D.R, Derewenda, U, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | | Deposit date: | 2009-05-06 | | Release date: | 2009-07-14 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of Tm1865, an Endonuclease V from Thermotoga Maritima
To be Published
|
|
1MLA
 | | THE ESCHERICHIA COLI MALONYL-COA:ACYL CARRIER PROTEIN TRANSACYLASE AT 1.5-ANGSTROMS RESOLUTION. CRYSTAL STRUCTURE OF A FATTY ACID SYNTHASE COMPONENT | | Descriptor: | MALONYL-COENZYME A ACYL CARRIER PROTEIN TRANSACYLASE | | Authors: | Serre, L, Verbree, E.C, Dauter, Z, Stuitje, A.R, Derewenda, Z.S. | | Deposit date: | 1995-01-25 | | Release date: | 1996-03-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-A resolution. Crystal structure of a fatty acid synthase component.
J.Biol.Chem., 270, 1995
|
|
3MSX
 | | Crystal structure of RhoA.GDP.MgF3 in complex with GAP domain of ArhGAP20 | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 20, ... | | Authors: | Utepbergenov, D, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2010-04-29 | | Release date: | 2011-03-16 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Mechanism of molecular specificity of RhoGAP domains towards small GTPases of RhoA family.
To be Published
|
|
3N77
 | | Crystal structure of Idp01880, putative NTP pyrophosphohydrolase of Salmonella typhimurium LT2 | | Descriptor: | Nucleoside triphosphatase nudI | | Authors: | Frydrysiak, J, Cooper, D.R, Derewenda, U, Anderson, W.F, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI), Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2010-05-26 | | Release date: | 2010-08-18 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Crystal structure of Idp01880, putative NTP pyrophosphohydrolase of Salmonella typhimurium LT2
To be Published
|
|
1MG4
 | | STRUCTURE OF N-TERMINAL DOUBLECORTIN DOMAIN FROM DCLK: WILD TYPE PROTEIN | | Descriptor: | DOUBLECORTIN-LIKE KINASE (N-TERMINAL DOMAIN), SULFATE ION | | Authors: | Kim, M.H, Cierpickil, T, Derewenda, U, Krowarsch, D, Feng, Y, Devedjiev, Y, Dauter, Z, Walsh, C.A, Otlewski, J, Bushweller, J.H, Derewenda, Z. | | Deposit date: | 2002-08-14 | | Release date: | 2003-04-29 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.504 Å) | | Cite: | The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase
Nat.Struct.Biol., 10, 2003
|
|
1BWQ
 | | PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | Descriptor: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | Authors: | Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z. | | Deposit date: | 1998-09-27 | | Release date: | 1999-05-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
|
|
1BWR
 | | PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | Descriptor: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | Authors: | Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z. | | Deposit date: | 1998-09-27 | | Release date: | 1999-05-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
|
|
1BWP
 | | PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | Descriptor: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | | Authors: | Ho, Y.S, Sheffield, P.J, Masuyama, J, Arai, H, Li, J, Aoki, J, Inoue, K, Derewenda, U, Derewenda, Z. | | Deposit date: | 1998-09-27 | | Release date: | 1999-05-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
|
|
1MFW
 | | STRUCTURE OF N-TERMINAL DOUBLECORTIN DOMAIN FROM DCLK: SELENOMETHIONINE LABELED PROTEIN | | Descriptor: | DOUBLECORTIN-LIKE KINASE (N-TERMINAL DOMAIN), SULFATE ION | | Authors: | Kim, M.H, Cierpickil, T, Derewenda, U, Krowarsch, D, Feng, Y, Devedjiev, Y, Dauter, Z, Walsh, C.A, Otlewski, J, Bushweller, J.H, Derewenda, Z. | | Deposit date: | 2002-08-13 | | Release date: | 2003-04-29 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase
Nat.Struct.Biol., 10, 2003
|
|
3QOR
 | |
3FMS
 | | Crystal structure of TM0439, a GntR transcriptional regulator | | Descriptor: | ACETATE ION, NICKEL (II) ION, Transcriptional regulator, ... | | Authors: | Zheng, M, Cooper, D.R, Yu, M, Hung, L.-W, Derewenda, U, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | | Deposit date: | 2008-12-22 | | Release date: | 2009-02-10 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains.
Acta Crystallogr.,Sect.D, 65, 2009
|
|
1KTJ
 | | X-ray Structure Of Der P 2, The Major House Dust Mite Allergen | | Descriptor: | ALLERGEN DER P 2 | | Authors: | Derewenda, U, Li, J, Derewenda, Z, Dauter, Z, Mueller, G.A, Rule, G.S, Benjamin, D.C. | | Deposit date: | 2002-01-16 | | Release date: | 2002-05-15 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The crystal structure of a major dust mite allergen Der p 2, and its biological implications.
J.Mol.Biol., 318, 2002
|
|
3FHK
 | | Crystal structure of APC1446, B.subtilis YphP disulfide isomerase | | Descriptor: | SULFATE ION, UPF0403 protein yphP | | Authors: | Derewenda, U, Boczek, T, Cooper, D.R, Yu, M, Hung, L, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | | Deposit date: | 2008-12-09 | | Release date: | 2009-09-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure and function of Bacillus subtilis YphP, a prokaryotic disulfide isomerase with a CXC catalytic motif .
Biochemistry, 48, 2009
|
|
3H3E
 | | Crystal structure of Tm1679, A METAL-DEPENDENT HYDROLASE OF THE BETA-LACTAMASE SUPERFAMILY | | Descriptor: | ZINC ION, uncharacterized protein Tm1679 | | Authors: | Cooper, D.R, Olekhnovitch, N, Derewenda, U, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | | Deposit date: | 2009-04-16 | | Release date: | 2009-07-14 | | Last modified: | 2021-10-13 | | Method: | X-RAY DIFFRACTION (2.749 Å) | | Cite: | Crystal structure of Tm1679, A METAL-DEPENDENT HYDROLASE OF THE BETA-LACTAMASE SUPERFAMILY
To be Published
|
|
2AAA
 | | CALCIUM BINDING IN ALPHA-AMYLASES: AN X-RAY DIFFRACTION STUDY AT 2.1 ANGSTROMS RESOLUTION OF TWO ENZYMES FROM ASPERGILLUS | | Descriptor: | ALPHA-AMYLASE, CALCIUM ION | | Authors: | Brady, L, Brzozowski, A.M, Derewenda, Z, Dodson, E.J, Dodson, G.G. | | Deposit date: | 1991-02-27 | | Release date: | 1993-07-15 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Calcium binding in alpha-amylases: an X-ray diffraction study at 2.1-A resolution of two enzymes from Aspergillus.
Biochemistry, 29, 1990
|
|
5TGL
 | | A MODEL FOR INTERFACIAL ACTIVATION IN LIPASES FROM THE STRUCTURE OF A FUNGAL LIPASE-INHIBITOR COMPLEX | | Descriptor: | LIPASE, N-HEXYLPHOSPHONATE ETHYL ESTER | | Authors: | Brzozowski, A.M, Derewenda, U, Derewenda, Z.S, Dodson, G.G, Lawson, D, Turkenburg, J.P, Bjorkling, F, Huge-Jensen, B, Patkar, S.R, Thim, L. | | Deposit date: | 1991-10-30 | | Release date: | 1994-01-31 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex.
Nature, 351, 1991
|
|
2BQQ
 | | X-ray Structure of the N-terminal Domain of Human Doublecortin | | Descriptor: | NEURONAL MIGRATION PROTEIN DOUBLECORTIN | | Authors: | Kim, M.H, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2005-04-27 | | Release date: | 2006-07-19 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Dc-Module of Doublecortin: Dynamics, Domain Boundaries, and Functional Implications.
Proteins, 64, 2006
|
|
5VIM
 | |
5VKD
 | | Crystal structure of C-terminal domain of Ebola (Bundibugyo) nucleoprotein in complex with Fab fragment | | Descriptor: | Fab Heavy Chain, Fab light chain, Nucleoprotein | | Authors: | Radwanska, M.J, Derewenda, U, Kossiakoff, A, Derewenda, Z.S. | | Deposit date: | 2017-04-21 | | Release date: | 2018-04-25 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.749 Å) | | Cite: | The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab.
Acta Crystallogr D Struct Biol, 74, 2018
|
|
5VZ1
 | | Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) | | Descriptor: | Apo Antibody Fab Heavy Chain, Apo Antibody Fab Light Chain, ZINC ION | | Authors: | Radwanska, M.J, Derewenda, U, Kossiakoff, A, Derewenda, Z.S. | | Deposit date: | 2017-05-26 | | Release date: | 2018-06-27 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.112 Å) | | Cite: | Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains)
To Be Published
|
|
