3TV0
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1FXW
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5W2B
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![BU of 5w2b by Molmil](/molmil-images/mine/5w2b) | Crystal structure of C-terminal domain of Ebola (Reston) nucleoprotein in complex with Fab fragment | Descriptor: | Fab Heavy Chain, Fab Light Chain, Nucleoprotein | Authors: | Radwanska, M.J, Derewenda, U, Kossiakoff, A.A, Derewenda, Z.S. | Deposit date: | 2017-06-06 | Release date: | 2018-06-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. Acta Crystallogr D Struct Biol, 74, 2018
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1ESD
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![BU of 1esd by Molmil](/molmil-images/mine/1esd) | THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES | Descriptor: | ESTERASE, METHYLPHOSPHONIC ACID ESTER GROUP | Authors: | Wei, Y, Schottel, J.L, Derewenda, U, Swenson, L, Patkar, S, Derewenda, Z.S. | Deposit date: | 1994-10-07 | Release date: | 1995-10-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A novel variant of the catalytic triad in the Streptomyces scabies esterase. Nat.Struct.Biol., 2, 1995
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1WAB
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![BU of 1wab by Molmil](/molmil-images/mine/1wab) | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | Descriptor: | ACETATE ION, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE | Authors: | Ho, Y.S, Swenson, L, Derewenda, U, Serre, L, Wei, Y, Dauter, Z, Hattori, M, Aoki, J, Arai, H, Adachi, T, Inoue, K, Derewenda, Z.S. | Deposit date: | 1996-10-30 | Release date: | 1997-11-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer. Nature, 385, 1997
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5DSD
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![BU of 5dsd by Molmil](/molmil-images/mine/5dsd) | The crystal structure of the C-terminal domain of Ebola (Bundibugyo) nucleoprotein | Descriptor: | CHLORIDE ION, GLYCEROL, Nucleoprotein | Authors: | Baker, L, Handing, K.B, Utepbergenov, D, Derewenda, U, Derewenda, Z.S. | Deposit date: | 2015-09-17 | Release date: | 2015-09-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses. Acta Crystallogr D Struct Biol, 72, 2016
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1W9E
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![BU of 1w9e by Molmil](/molmil-images/mine/1w9e) | Crystal structure of the PDZ tandem of human syntenin in complex with TNEFYF peptide | Descriptor: | BENZOIC ACID, SYNTENIN 1, TNEFYF PEPTIDE | Authors: | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | Deposit date: | 2004-10-09 | Release date: | 2006-03-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | The Binding of the Pdz Tandem of Syntenin to Target Proteins. Biochemistry, 45, 2006
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1W9O
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![BU of 1w9o by Molmil](/molmil-images/mine/1w9o) | Crystal structure of the PDZ tandem of human syntenin in complex with TNEYYV peptide | Descriptor: | BENZOIC ACID, SYNTENIN 1, TNEYYV PEPTIDE | Authors: | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | Deposit date: | 2004-10-15 | Release date: | 2006-03-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The Binding of the Pdz Tandem of Syntenin to Target Proteins. Biochemistry, 45, 2006
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6INS
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![BU of 6ins by Molmil](/molmil-images/mine/6ins) | X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE | Descriptor: | INSULIN, ZINC ION | Authors: | Derewenda, U, Derewenda, Z, Dodson, E.J, Dodson, G.G, Bing, X, Markussen, J. | Deposit date: | 1992-11-25 | Release date: | 1994-01-31 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue. J.Mol.Biol., 220, 1991
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6B6Z
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![BU of 6b6z by Molmil](/molmil-images/mine/6b6z) | Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) | Descriptor: | Apo Fab Heavy Chain, Apo Fab Light Chain, ZINC ION | Authors: | Radwanska, M.J, Derewenda, U, Kossiakoff, A.A, Derewenda, Z.S. | Deposit date: | 2017-10-03 | Release date: | 2018-12-19 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.112 Å) | Cite: | Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) To Be Published
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5E2X
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![BU of 5e2x by Molmil](/molmil-images/mine/5e2x) | The crystal structure of the C-terminal domain of Ebola (Tai Forest) nucleoprotein | Descriptor: | NONAETHYLENE GLYCOL, NP | Authors: | Baker, L.E, Handing, K.B, Derewenda, U, Utepbergenov, D, Derewenda, Z.S. | Deposit date: | 2015-10-01 | Release date: | 2015-10-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses. Acta Crystallogr D Struct Biol, 72, 2016
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4GUE
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![BU of 4gue by Molmil](/molmil-images/mine/4gue) | Structure of N-terminal kinase domain of RSK2 with flavonoid glycoside quercitrin | Descriptor: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside, MAGNESIUM ION, Ribosomal protein S6 kinase alpha-3, ... | Authors: | Derewenda, U, Utepbergenov, D, Szukalska, G, Derewenda, Z.S. | Deposit date: | 2012-08-29 | Release date: | 2013-01-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Identification of quercitrin as an inhibitor of the p90 S6 ribosomal kinase (RSK): structure of its complex with the N-terminal domain of RSK2 at 1.8 A resolution. Acta Crystallogr.,Sect.D, 69, 2013
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4EL9
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![BU of 4el9 by Molmil](/molmil-images/mine/4el9) | Structure of N-terminal kinase domain of RSK2 with afzelin | Descriptor: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside, Ribosomal protein S6 kinase alpha-3 | Authors: | Utepbergenov, D, Derewenda, U, Derewenda, Z.S. | Deposit date: | 2012-04-10 | Release date: | 2012-09-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Insights into the Inhibition of the p90 Ribosomal S6 Kinase (RSK) by the Flavonol Glycoside SL0101 from the 1.5 A Crystal Structure of the N-Terminal Domain of RSK2 with Bound Inhibitor. Biochemistry, 51, 2012
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4TGL
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![BU of 4tgl by Molmil](/molmil-images/mine/4tgl) | CATALYSIS AT THE INTERFACE: THE ANATOMY OF A CONFORMATIONAL CHANGE IN A TRIGLYCERIDE LIPASE | Descriptor: | DIETHYL PHOSPHONATE, TRIACYL-GLYCEROL ACYLHYDROLASE | Authors: | Derewenda, U, Brzozowski, A.M, Lawson, D, Derewenda, Z.S. | Deposit date: | 1991-07-29 | Release date: | 1993-07-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Catalysis at the interface: the anatomy of a conformational change in a triglyceride lipase. Biochemistry, 31, 1992
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5IRC
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![BU of 5irc by Molmil](/molmil-images/mine/5irc) | p190A GAP domain complex with RhoA | Descriptor: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Derewenda, U, Derewenda, Z. | Deposit date: | 2016-03-12 | Release date: | 2016-08-17 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS. J.Biol.Chem., 291, 2016
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1MLA
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![BU of 1mla by Molmil](/molmil-images/mine/1mla) | THE ESCHERICHIA COLI MALONYL-COA:ACYL CARRIER PROTEIN TRANSACYLASE AT 1.5-ANGSTROMS RESOLUTION. CRYSTAL STRUCTURE OF A FATTY ACID SYNTHASE COMPONENT | Descriptor: | MALONYL-COENZYME A ACYL CARRIER PROTEIN TRANSACYLASE | Authors: | Serre, L, Verbree, E.C, Dauter, Z, Stuitje, A.R, Derewenda, Z.S. | Deposit date: | 1995-01-25 | Release date: | 1996-03-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-A resolution. Crystal structure of a fatty acid synthase component. J.Biol.Chem., 270, 1995
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2V71
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![BU of 2v71 by Molmil](/molmil-images/mine/2v71) | Coiled-coil region of NudEL | Descriptor: | NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1 | Authors: | Derewenda, U, Cooper, D.R, Kim, M.H, Derewenda, Z.S. | Deposit date: | 2007-07-25 | Release date: | 2007-11-27 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | The Structure of the Coiled-Coil Domain of Ndel1 and the Basis of its Interaction with Lis1, the Causal Protein of Miller-Dieker Lissencephaly. Structure, 15, 2007
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4QAZ
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4QB0
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5TGL
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![BU of 5tgl by Molmil](/molmil-images/mine/5tgl) | A MODEL FOR INTERFACIAL ACTIVATION IN LIPASES FROM THE STRUCTURE OF A FUNGAL LIPASE-INHIBITOR COMPLEX | Descriptor: | LIPASE, N-HEXYLPHOSPHONATE ETHYL ESTER | Authors: | Brzozowski, A.M, Derewenda, U, Derewenda, Z.S, Dodson, G.G, Lawson, D, Turkenburg, J.P, Bjorkling, F, Huge-Jensen, B, Patkar, S.R, Thim, L. | Deposit date: | 1991-10-30 | Release date: | 1994-01-31 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex. Nature, 351, 1991
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6TAA
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![BU of 6taa by Molmil](/molmil-images/mine/6taa) | STRUCTURE AND MOLECULAR MODEL REFINEMENT OF ASPERGILLUS ORYZAE (TAKA) ALPHA-AMYLASE: AN APPLICATION OF THE SIMULATED-ANNEALING METHOD | Descriptor: | ALPHA-AMYLASE, CALCIUM ION | Authors: | Swift, H.J, Brady, L, Derewenda, Z.S, Dodson, E.J, Turkenburg, J.P, Wilkinson, A.J. | Deposit date: | 1992-08-21 | Release date: | 1993-10-31 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure and molecular model refinement of Aspergillus oryzae (TAKA) alpha-amylase: an application of the simulated-annealing method. Acta Crystallogr.,Sect.B, 47, 1991
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1VYH
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![BU of 1vyh by Molmil](/molmil-images/mine/1vyh) | PAF-AH Holoenzyme: Lis1/Alfa2 | Descriptor: | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB ALPHA SUBUNIT, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB BETA SUBUNIT | Authors: | Tarricone, C, Perrina, F, Monzani, S, Massimiliano, L, Knapp, S, Tsai, L.-H, Derewenda, Z.S, Musacchio, A. | Deposit date: | 2004-04-30 | Release date: | 2005-05-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Coupling Paf Signaling to Dynein Regulation: Structure of Lis1 in Complex with Paf-Acetylhydrolase. Neuron, 44, 2004
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1ZNJ
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![BU of 1znj by Molmil](/molmil-images/mine/1znj) | INSULIN, MONOCLINIC CRYSTAL FORM | Descriptor: | CHLORIDE ION, INSULIN, PHENOL, ... | Authors: | Turkenburg, M.G.W, Whittingham, J.L, Turkenburg, J.P, Dodson, G.G, Derewenda, U, Smith, G.D, Dodson, E.J, Derewenda, Z.S, Xiao, B. | Deposit date: | 1997-09-23 | Release date: | 1998-01-28 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure Determination and Refinement of Two Crystal Forms of Native Insulins To be Published
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5VIM
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5VKD
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![BU of 5vkd by Molmil](/molmil-images/mine/5vkd) | Crystal structure of C-terminal domain of Ebola (Bundibugyo) nucleoprotein in complex with Fab fragment | Descriptor: | Fab Heavy Chain, Fab light chain, Nucleoprotein | Authors: | Radwanska, M.J, Derewenda, U, Kossiakoff, A, Derewenda, Z.S. | Deposit date: | 2017-04-21 | Release date: | 2018-04-25 | Last modified: | 2022-11-16 | Method: | X-RAY DIFFRACTION (1.749 Å) | Cite: | The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. Acta Crystallogr D Struct Biol, 74, 2018
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