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PDB: 5 results
8GCC
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BU of 8gcc by Molmil
T. cruzi topoisomerase II alpha bound to dsDNA and the covalent inhibitor CT1
Descriptor: 2-{3-[(Z)-iminomethyl]-1H-1,2,4-triazol-1-yl}-1-{(3M)-3-[2-(trifluoromethyl)phenyl]-6H-pyrrolo[3,4-b]pyridin-6-yl}ethan-1-one, DNA (28-MER), DNA topoisomerase 2
Authors:Schenk, A, Deniston, C, Noeske, J.
Deposit date:2023-03-01
Release date:2023-07-12
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections.
Science, 380, 2023
6VNO
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BU of 6vno by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
Authors:Leschziner, A, Deniston, C, Lahiri, I.
Deposit date:2020-01-29
Release date:2020-08-26
Last modified:2020-12-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP6
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BU of 6vp6 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
Authors:Leschziner, A, Deniston, C, Lahiri, I.
Deposit date:2020-02-01
Release date:2020-08-26
Last modified:2020-12-23
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP8
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BU of 6vp8 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor: Leucine-rich repeat serine/threonine-protein kinase 2
Authors:Leschziner, A, Deniston, C, Lahiri, I.
Deposit date:2020-02-01
Release date:2020-08-26
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP7
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BU of 6vp7 by Molmil
Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
Descriptor: Leucine-rich repeat serine/threonine-protein kinase 2
Authors:Leschziner, A, Deniston, C, Lahiri, I.
Deposit date:2020-02-01
Release date:2020-08-26
Last modified:2020-12-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020

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