Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 87 件
4JG1
DownloadVisualize
BU of 4jg1 by Molmil
Structure of phosphoserine/threonine (pSTAb) scaffold bound to pThr peptide
分子名称: Fab heavy chain, Fab light chain, PROPANOIC ACID, ...
著者Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A.
登録日2013-02-28
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Nature-inspired design of motif-specific antibody scaffolds.
Nat.Biotechnol., 31, 2013
2LY0
DownloadVisualize
BU of 2ly0 by Molmil
Solution NMR structure of the influenza A virus S31N mutant (19-49) in presence of drug M2WJ332
分子名称: (3S,5S,7S)-N-{[5-(thiophen-2-yl)-1,2-oxazol-3-yl]methyl}tricyclo[3.3.1.1~3,7~]decan-1-aminium, Membrane ion channel M2
著者Wu, Y, Wang, J, DeGrado, W.
登録日2012-09-10
公開日2013-01-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus.
Proc.Natl.Acad.Sci.USA, 110, 2013
2MUV
DownloadVisualize
BU of 2muv by Molmil
NOE-based model of the influenza A virus M2 (19-49) bound to drug 11
分子名称: (3s,5s,7s)-N-[(5-bromothiophen-2-yl)methyl]tricyclo[3.3.1.1~3,7~]decan-1-aminium, Matrix protein 2
著者Wu, Y, Wang, J, DeGrado, W.
登録日2014-09-18
公開日2014-12-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Flipping in the Pore: Discovery of Dual Inhibitors That Bind in Different Orientations to the Wild-Type versus the Amantadine-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel.
J.Am.Chem.Soc., 136, 2014
4JFY
DownloadVisualize
BU of 4jfy by Molmil
Apo structure of phosphotyrosine (pYAb) scaffold
分子名称: Fab heavy chain, Fab light chain, TETRAETHYLENE GLYCOL
著者Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A.
登録日2013-02-28
公開日2013-08-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Nature-inspired design of motif-specific antibody scaffolds.
Nat.Biotechnol., 31, 2013
2MUW
DownloadVisualize
BU of 2muw by Molmil
NOE-based model of the influenza A virus N31S mutant (19-49) bound to drug 11
分子名称: (3s,5s,7s)-N-[(5-bromothiophen-2-yl)methyl]tricyclo[3.3.1.1~3,7~]decan-1-aminium, Matrix protein 2
著者Wu, Y, Wang, J, DeGrado, W.
登録日2014-09-18
公開日2014-12-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Flipping in the Pore: Discovery of Dual Inhibitors That Bind in Different Orientations to the Wild-Type versus the Amantadine-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel.
J.Am.Chem.Soc., 136, 2014
4JFZ
DownloadVisualize
BU of 4jfz by Molmil
Structure of phosphoserine (pSAb) scaffold bound to pSer peptide
分子名称: Fab heavy chain, Fab light chain, PROPANOIC ACID, ...
著者Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A.
登録日2013-02-28
公開日2013-08-28
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Nature-inspired design of motif-specific antibody scaffolds.
Nat.Biotechnol., 31, 2013
2LFF
DownloadVisualize
BU of 2lff by Molmil
Solution structure of Diiron protein in presence of 8 eq Zn2+, Northeast Structural Genomics consortium target OR21
分子名称: Diiron protein, ZINC ION
著者Pires, M, Wu, Y, Mills, J.L, Reig, A, Englander, W, Degrado, W, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2011-06-29
公開日2011-08-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of Diiron protein in presence of 8 eq Zn2+
To be Published
3S0R
DownloadVisualize
BU of 3s0r by Molmil
Crystal Structure of De novo Designed helical assembly protein
分子名称: De novo designed Helical Assembly
著者Acharya, R, Grigoryan, G, Kim, Y.H, DeGrado, W.F.
登録日2011-05-13
公開日2011-06-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.453 Å)
主引用文献Computational design of virus-like protein assemblies on carbon nanotube surfaces.
Science, 332, 2011
5TTC
DownloadVisualize
BU of 5ttc by Molmil
XFEL structure of influenza A M2 wild type TM domain at high pH in the lipidic cubic phase at room temperature
分子名称: CALCIUM ION, CHLORIDE ION, Matrix protein 2
著者Thomaston, J.L, Woldeyes, R.A, Fraser, J.S, DeGrado, W.F.
登録日2016-11-02
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6MCT
DownloadVisualize
BU of 6mct by Molmil
A designed pentameric membrane protein stabilized by van der Waals interaction
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SULFATE ION, mini-eVgL membrane protein
著者Mravic, M, Liu, L, Degrado, W.F.
登録日2018-09-02
公開日2019-04-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Packing of apolar side chains enables accurate design of highly stable membrane proteins.
Science, 363, 2019
6MPW
DownloadVisualize
BU of 6mpw by Molmil
De Novo Design of membrane protein--mini-eVgL membrane protein, C2221 form-1
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, mini-eVgL membrane protein
著者Mravic, M, Liu, L, DeGrado, W.F.
登録日2018-10-08
公開日2019-04-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Packing of apolar side chains enables accurate design of highly stable membrane proteins.
Science, 363, 2019
5V2Q
DownloadVisualize
BU of 5v2q by Molmil
CaV beta2a subunit: CaV1.2 AID-CEN complex
分子名称: 1,3-bis(bromomethyl)benzene, CHLORIDE ION, Voltage-dependent L-type calcium channel subunit alpha-1C, ...
著者Findeisen, F, Campiglio, M, Jo, H, Rumpf, C.H, Pope, L, Flucher, B, Degrado, W.F, Minor, D.L.
登録日2017-03-06
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Stapled Voltage-Gated Calcium Channel (CaV) alpha-Interaction Domain (AID) Peptides Act As Selective Protein-Protein Interaction Inhibitors of CaV Function.
ACS Chem Neurosci, 8, 2017
5WLL
DownloadVisualize
BU of 5wll by Molmil
De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4DH1
分子名称: GLYCEROL, Helical Bundle 4DH1, ZINC ION
著者Zhang, S.-Q, Liu, L, DeGrado, W.F.
登録日2017-07-27
公開日2018-01-03
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles.
J. Am. Chem. Soc., 140, 2018
5WOD
DownloadVisualize
BU of 5wod by Molmil
De Novo Design of Covalently Constrained Meso-size Protein Scaffolds with Unique Tertiary Structures
分子名称: 38-mer peptide
著者Wu, H, Wu, Y, DeGrado, W.F.
登録日2017-08-01
公開日2017-10-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WLK
DownloadVisualize
BU of 5wlk by Molmil
De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4EH2
分子名称: Helical Bundle 4EH2, ZINC ION
著者Zhang, S.-Q, Liu, L, DeGrado, W.F.
登録日2017-07-27
公開日2018-01-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles.
J. Am. Chem. Soc., 140, 2018
5WOC
DownloadVisualize
BU of 5woc by Molmil
De Novo Design of Covalently Constrained Meso-size Protein Scaffolds with Unique Tertiary Structures
分子名称: (3-methylphenyl)methanol, SER-PRO-GLU-GLU-ARG-ALA-GLN-LEU-CYS-THR-ALA-ALA-GLU-LYS-ALA-ASP-GLU-LEU-GLY
著者Wu, H, Wu, Y, DeGrado, W.F.
登録日2017-08-01
公開日2017-10-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1COI
DownloadVisualize
BU of 1coi by Molmil
DESIGNED TRIMERIC COILED COIL-VALD
分子名称: COIL-VALD, SULFATE ION
著者Ogihara, N.L, Weiss, M.S, Degrado, W.F, Eisenberg, D.
登録日1996-08-10
公開日1997-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of the designed trimeric coiled coil coil-VaLd: implications for engineering crystals and supramolecular assemblies.
Protein Sci., 6, 1997
5WLJ
DownloadVisualize
BU of 5wlj by Molmil
De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4EH1
分子名称: De Novo Metal Binding Helical Bundle, ZINC ION
著者Zhang, S.-Q, Liu, L, DeGrado, W.F.
登録日2017-07-27
公開日2018-01-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles.
J. Am. Chem. Soc., 140, 2018
5WLM
DownloadVisualize
BU of 5wlm by Molmil
De Novo Design of Polynuclear Transition Metal Clusters in Helix Bundles-4DH2
分子名称: Helical Bundle 4DH2, ZINC ION
著者Zhang, S.-Q, Liu, L, DeGrado, W.F.
登録日2017-07-27
公開日2018-01-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献De Novo Design of Tetranuclear Transition Metal Clusters Stabilized by Hydrogen-Bonded Networks in Helical Bundles.
J. Am. Chem. Soc., 140, 2018
4P6J
DownloadVisualize
BU of 4p6j by Molmil
Crystal Structure of the Computationally Designed Transmembrane Metallotransporter with 4-bromophenylalanine in Octyl Glucoside
分子名称: Computationally Designed Transporter of Zn(II) and Proton, SULFATE ION
著者Joh, N.H, Acharya, R, DeGrado, W.F.
登録日2014-03-25
公開日2014-12-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献De novo design of a transmembrane Zn2+-transporting four-helix bundle.
Science, 346, 2014
4P6L
DownloadVisualize
BU of 4p6l by Molmil
Crystal Structure of the Computationally Designed Transmembrane Metallotransporter in Octyl Glucoside
分子名称: Computationally Designed Transporter of Zn(II) and proton
著者Joh, N.H, Acharya, R, DeGrado, W.F.
登録日2014-03-25
公開日2014-12-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献De novo design of a transmembrane Zn2+-transporting four-helix bundle.
Science, 346, 2014
4P6K
DownloadVisualize
BU of 4p6k by Molmil
Crystal Structure of the Computationally Designed Transmembrane Metallotransporter with 4-bromophenylalanine in Lipidic Cubic Phase
分子名称: Computationally Designed Transporter of Zn(II) and Proton
著者Joh, N.H, Acharya, R, DeGrado, W.F.
登録日2014-03-25
公開日2014-12-24
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献De novo design of a transmembrane Zn2+-transporting four-helix bundle.
Science, 346, 2014
6MJH
DownloadVisualize
BU of 6mjh by Molmil
The S31N mutant of the influenza A M2 proton channel in two distinct conformational states
分子名称: CALCIUM ION, CHLORIDE ION, Matrix protein 2
著者Thomaston, J.L, DeGrado, W.F.
登録日2018-09-20
公開日2019-06-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献X-ray Crystal Structure of the Influenza A M2 Proton Channel S31N Mutant in Two Conformational States: An Open and Shut Case.
J.Am.Chem.Soc., 141, 2019
6MQU
DownloadVisualize
BU of 6mqu by Molmil
PL5, synthetic transmembrane domain variant of human phospholamban
分子名称: PL5, designed TM pentamer
著者Mravic, M, Thomaston, J.L, DeGrado, W.F.
登録日2018-10-10
公開日2019-04-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Packing of apolar side chains enables accurate design of highly stable membrane proteins.
Science, 363, 2019
6MQ2
DownloadVisualize
BU of 6mq2 by Molmil
De Novo Design of membrane protein--mini-eVgL membrane protein, C2221 form-2
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, mini-eVgL membrane protein
著者Mravic, M, Liu, L, Degrado, W.F.
登録日2018-10-09
公開日2019-04-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Packing of apolar side chains enables accurate design of highly stable membrane proteins.
Science, 363, 2019

222926

件を2024-07-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon