2JK1
| Crystal structure of the wild-type HupR receiver domain | 分子名称: | HYDROGENASE TRANSCRIPTIONAL REGULATORY PROTEIN HUPR1, MAGNESIUM ION | 著者 | Davies, K.M, Lowe, E.D, Venien-Bryan, C, Johnson, L.N. | 登録日 | 2008-05-26 | 公開日 | 2008-11-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Hupr Receiver Domain Crystal Structure in its Nonphospho and Inhibitory Phospho States. J.Mol.Biol., 385, 2009
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2VUH
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2VUI
| Crystal structure of the HupR receiver domain in inhibitory phospho- state | 分子名称: | BERYLLIUM TRIFLUORIDE ION, HYDROGENASE TRANSCRIPTIONAL REGULATORY PROTEIN HUPR1, MAGNESIUM ION | 著者 | Davies, K.M, Lowe, E.D, Venien-Bryan, C, Johnson, L.N. | 登録日 | 2008-05-26 | 公開日 | 2008-11-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The Hupr Receiver Domain Crystal Structure in its Nonphospho and Inhibitory Phospho States. J.Mol.Biol., 385, 2009
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4B2Q
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5V1T
| Crystal structure of Streptococcus suis SuiB bound to precursor peptide SuiA | 分子名称: | IRON/SULFUR CLUSTER, METHIONINE, Radical SAM, ... | 著者 | Davis, K.M, Bacik, J.P, Ando, N. | 登録日 | 2017-03-02 | 公開日 | 2017-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5V1S
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6VP4
| Ethylene forming enzyme (EFE) in complex with Fe(II), L-arginine, and 2OG | 分子名称: | 2-OXOGLUTARIC ACID, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ... | 著者 | Davis, K.M, Copeland, R.A, Boal, A.K. | 登録日 | 2020-02-01 | 公開日 | 2021-02-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | An Iron(IV)-Oxo Intermediate Initiating l-Arginine Oxidation but Not Ethylene Production by the 2-Oxoglutarate-Dependent Oxygenase, Ethylene-Forming Enzyme. J.Am.Chem.Soc., 143, 2021
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5V1Q
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7LTB
| Crystal Structure of Keratinicyclin B | 分子名称: | (2~{S},4~{S},5~{R},6~{S})-4-azanyl-5-methoxy-6-methyl-oxan-2-ol, 3-ammonio-2,3,6-trideoxy-alpha-L-arabino-hexopyranose-(1-2)-beta-D-glucopyranose, FORMIC ACID, ... | 著者 | Davis, K.M, Jeffrey, P.D, Seyedsayamdost, M.R. | 登録日 | 2021-02-19 | 公開日 | 2022-12-07 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | Potent and specific antibiotic combination therapy against Clostridioides difficile. Nat.Chem.Biol., 20, 2024
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7LKC
| Crystal Structure of Keratinimicin A | 分子名称: | (2~{S},4~{S},5~{R},6~{S})-4-azanyl-5-methoxy-6-methyl-oxan-2-ol, CHLORIDE ION, FORMIC ACID, ... | 著者 | Davis, K.M, Jeffrey, P.D, Seyedsayamdost, M.R. | 登録日 | 2021-02-02 | 公開日 | 2022-12-07 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | Potent and specific antibiotic combination therapy against Clostridioides difficile. Nat.Chem.Biol., 20, 2024
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6EDH
| Taurine:2OG dioxygenase (TauD) bound to the vanadyl ion, taurine, and succinate | 分子名称: | 2-AMINOETHANESULFONIC ACID, ACETATE ION, Alpha-ketoglutarate-dependent taurine dioxygenase, ... | 著者 | Davis, K.M, Altmyer, M, Boal, A.K. | 登録日 | 2018-08-09 | 公開日 | 2019-08-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.73000407 Å) | 主引用文献 | Structure of a Ferryl Mimic in the Archetypal Iron(II)- and 2-(Oxo)-glutarate-Dependent Dioxygenase, TauD. Biochemistry, 58, 2019
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6VP5
| Ethylene forming enzyme (EFE) D191E variant in complex with Fe(II), L-arginine, and 2OG | 分子名称: | 2-OXOGLUTARIC ACID, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ... | 著者 | Davis, K.M, Copeland, R.A, Boal, A.K. | 登録日 | 2020-02-01 | 公開日 | 2021-02-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | An Iron(IV)-Oxo Intermediate Initiating l-Arginine Oxidation but Not Ethylene Production by the 2-Oxoglutarate-Dependent Oxygenase, Ethylene-Forming Enzyme. J.Am.Chem.Soc., 143, 2021
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6NBQ
| T.elongatus NDH (data-set 1) | 分子名称: | IRON/SULFUR CLUSTER, NAD(P)H-quinone oxidoreductase chain 4 1, NAD(P)H-quinone oxidoreductase subunit 2, ... | 著者 | Laughlin, T.G, Bayne, A, Trempe, J.-F, Savage, D.F, Davies, K.M. | 登録日 | 2018-12-09 | 公開日 | 2019-02-27 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of the complex I-like molecule NDH of oxygenic photosynthesis. Nature, 566, 2019
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6NBX
| T.elongatus NDH (data-set 2) | 分子名称: | IRON/SULFUR CLUSTER, NAD(P)H-quinone oxidoreductase chain 4 1, NAD(P)H-quinone oxidoreductase subunit 1, ... | 著者 | Laughlin, T.G, Bayne, A, Trempe, J.-F, Savage, D.F, Davies, K.M. | 登録日 | 2018-12-10 | 公開日 | 2019-02-27 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of the complex I-like molecule NDH of oxygenic photosynthesis. Nature, 566, 2019
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6OWG
| Structure of a synthetic beta-carboxysome shell, T=4 | 分子名称: | Ethanolamine utilization protein EutN/carboxysome structural protein Ccml, Microcompartments protein | 著者 | Sutter, M, Laughlin, T.G, Davies, K.M, Kerfeld, C.A. | 登録日 | 2019-05-09 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structure of a Syntheticbeta-Carboxysome Shell. Plant Physiol., 181, 2019
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6OWF
| Structure of a synthetic beta-carboxysome shell, T=3 | 分子名称: | Ethanolamine utilization protein EutN/carboxysome structural protein Ccml, Microcompartments protein | 著者 | Sutter, M, Laughlin, T.G, Davies, K.M, Kerfeld, C.A. | 登録日 | 2019-05-09 | 公開日 | 2019-09-25 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of a Syntheticbeta-Carboxysome Shell. Plant Physiol., 181, 2019
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6NBY
| T.elongatus NDH (composite model) | 分子名称: | IRON/SULFUR CLUSTER, NAD(P)H-quinone oxidoreductase chain 4 1, NAD(P)H-quinone oxidoreductase subunit 1, ... | 著者 | Laughlin, T.G, Bayne, A, Trempe, J.-F, Savage, D.F, Davies, K.M. | 登録日 | 2018-12-10 | 公開日 | 2019-02-27 | 最終更新日 | 2020-04-15 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of the complex I-like molecule NDH of oxygenic photosynthesis. Nature, 566, 2019
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8F91
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7T6C
| E. coli dihydroorotate dehydrogenase bound to the ubiquinone surrogate DCIP | 分子名称: | 2,6-bis(chloranyl)-4-[(4-hydroxyphenyl)amino]phenol, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Dihydroorotate dehydrogenase (quinone), ... | 著者 | Horwitz, S.M, Ambarian, J.A, Davis, K.M. | 登録日 | 2021-12-13 | 公開日 | 2022-03-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines. Rsc Chem Biol, 3, 2022
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7T5K
| E. coli dihydroorotate dehydrogenase bound to the inhibitor HQNO | 分子名称: | 2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE, Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, ... | 著者 | Horwitz, S.M, Ambarian, J.A, Davis, K.M. | 登録日 | 2021-12-12 | 公開日 | 2022-03-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines. Rsc Chem Biol, 3, 2022
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7T6H
| E. coli dihydroorotate dehydrogenase | 分子名称: | Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, OROTIC ACID | 著者 | Horwitz, S.M, Ambarian, J.A, Davis, K.M. | 登録日 | 2021-12-13 | 公開日 | 2022-03-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines. Rsc Chem Biol, 3, 2022
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7T5Y
| E. coli dihydroorotate dehydrogenase bound to the inhibitor HMNQ | 分子名称: | 3-methyl-2-[(2E)-non-2-en-1-yl]quinolin-4(1H)-one, Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, ... | 著者 | Horwitz, S.M, Ambarian, J.A, Davis, K.M. | 登録日 | 2021-12-13 | 公開日 | 2022-03-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines. Rsc Chem Biol, 3, 2022
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4PBU
| Serial Time-resolved crystallography of Photosystem II using a femtosecond X-ray laser The S1 state | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2,3-DIMETHYL-5-(3,7,11,15,19,23,27,31,35-NONAMETHYL-2,6,10,14,18,22,26,30,34-HEXATRIACONTANONAENYL-2,5-CYCLOHEXADIENE-1,4-DIONE-2,3-DIMETHYL-5-SOLANESYL-1,4-BENZOQUINONE, ... | 著者 | Kupitz, C, Basu, S, Grotjohann, I, Fromme, R, Zatsepin, N, Rendek, K.N, Hunter, M, Shoeman, R.L, White, T.A, Wang, D, James, D, Yang, J.H, Cobb, D.E, Reeder, B, Sierra, R.G, Liu, H, Barty, A, Aquila, A, Deponte, D, Kirian, R.A, Bari, S, Bergkamp, J.J, Beyerlein, K, Bogan, M.J, Caleman, C, Chao, T.-C, Conrad, C.E, Davis, K.M, Fleckenstein, H, Galli, L, Hau-Riege, S.P, Kassemeyer, S, Laksmono, H, Liang, M, Lomb, L, Marchesini, S, Martin, A.V, Messerschmidt, M, Milathianaki, D, Nass, K, Ros, A, Roy-Chowdhury, S, Schmidt, K, Seibert, M, Steinbrener, J, Stellato, F, Yan, L, Yoon, C, Moore, T.A, Moore, A.L, Pushkar, Y, Williams, G.J, Boutet, S, Doak, R.B, Weierstall, U, Frank, M, Chapman, H.N, Spence, J.C.H, Fromme, P. | 登録日 | 2014-04-13 | 公開日 | 2014-07-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (5 Å) | 主引用文献 | Serial time-resolved crystallography of photosystem II using a femtosecond X-ray laser. Nature, 513, 2014
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8G6C
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8G8V
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