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PDB: 130 件

3FHE
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Leukotriene A4 Hydrolase complexed with inhibitor N-[3-(4-benzylphenoxy)propyl]-N-methyl-beta-alanine.
分子名称: ACETATE ION, IMIDAZOLE, Leukotriene A-4 hydrolase, ...
著者Mamat, B, Davies, D.R.
登録日2008-12-09
公開日2010-01-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Discovery of 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic acid (DG-051) as a novel leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis.
J.Med.Chem., 53, 2010
2TGI
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CRYSTAL STRUCTURE OF TRANSFORMING GROWTH FACTOR-BETA2: AN UNUSUAL FOLD FOR THE SUPERFAMILY
分子名称: TRANSFORMING GROWTH FACTOR ,BETA 2
著者Daopin, S, Davies, D.R.
登録日1993-10-20
公開日1994-01-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily.
Science, 257, 1992
1D3R
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CRYSTAL STRUCTURE OF TRIPLEX DNA
分子名称: DNA (5'-D(*CP*(BRU)P*CP*CP*(BRU)P*CP*CP*GP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*CP*GP*GP*AP*G)-3')
著者Rhee, S, Han, Z.-J, Liu, K, Todd Miles, H.T, Davies, D.R.
登録日1999-09-30
公開日2000-01-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a triple helical DNA with a triplex-duplex junction.
Biochemistry, 38, 1999
2TRS
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CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
分子名称: INDOLE-3-PROPANOL PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE, ...
著者Rhee, S, Parris, K.D, Hyde, C.C, Ahmed, S.A, Miles, E.W, Davies, D.R.
登録日1997-01-07
公開日1997-04-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.
Biochemistry, 36, 1997
2TSY
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CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
分子名称: SN-GLYCEROL-3-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE, ...
著者Rhee, S, Parris, K.D, Hyde, C.C, Ahmed, S.A, Miles, E.W, Davies, D.R.
登録日1997-01-03
公開日1997-04-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.
Biochemistry, 36, 1997
2TYS
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CRYSTAL STRUCTURES OF MUTANT (BETAK87T) TRYPTOPHAN SYNTHASE ALPHA2 BETA2 COMPLEX WITH LIGANDS BOUND TO THE ACTIVE SITES OF THE ALPHA AND BETA SUBUNITS REVEAL LIGAND-INDUCED CONFORMATIONAL CHANGES
分子名称: SODIUM ION, TRYPTOPHAN SYNTHASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-L-TRYPTOPHANE
著者Rhee, S, Parris, K.D, Hyde, C.C, Ahmed, S.A, Miles, E.W, Davies, D.R.
登録日1997-01-08
公開日1997-04-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of a mutant (betaK87T) tryptophan synthase alpha2beta2 complex with ligands bound to the active sites of the alpha- and beta-subunits reveal ligand-induced conformational changes.
Biochemistry, 36, 1997
1CI4
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THE CRYSTAL STRUCTURE OF HUMAN BARRIER-TO-AUTOINTEGRATION FACTOR (BAF)
分子名称: PROTEIN (BARRIER-TO-AUTOINTEGRATION FACTOR (BAF))
著者Umland, T.C, Wei, S.-Q, Craigie, R, Davies, D.R.
登録日1999-04-07
公開日2000-08-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of DNA bridging by barrier-to-autointegration factor.
Biochemistry, 39, 2000
1DHS
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CRYSTAL STRUCTURE OF THE NAD COMPLEX OF HUMAN DEOXYHYPUSINE SYNTHASE
分子名称: DEOXYHYPUSINE SYNTHASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Liao, D.-I, Davies, D.R.
登録日1997-10-28
公開日1998-02-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the NAD complex of human deoxyhypusine synthase: an enzyme with a ball-and-chain mechanism for blocking the active site.
Structure, 6, 1998
6MBQ
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Crystal structure of Mg-free wild-type KRAS (2-166) bound to GMPPNP in the state 1 conformation
分子名称: 1,2-ETHANEDIOL, GTPase KRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Dharmaiah, S, Davies, D.R, Abendroth, J, Gillette, W.G, Stephen, A.G, Simanshu, D.K.
登録日2018-08-30
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structures of N-terminally processed KRAS provide insight into the role of N-acetylation.
Sci Rep, 9, 2019
1KPP
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Structure of the Tsg101 UEV domain
分子名称: Tumor susceptibility gene 101 protein
著者Pornillos, O, Alam, S.L, Rich, R.L, Myszka, D.G, Davis, D.R, Sundquist, W.I.
登録日2002-01-02
公開日2002-05-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and functional interactions of the Tsg101 UEV domain.
EMBO J., 21, 2002
1KPQ
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Structure of the Tsg101 UEV domain
分子名称: Tumor susceptibility gene 101 protein
著者Pornillos, O, Alam, S.L, Rich, R.L, Myszka, D.G, Davis, D.R, Sundquist, W.I.
登録日2002-01-02
公開日2002-05-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and functional interactions of the Tsg101 UEV domain.
EMBO J., 21, 2002
1M4P
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Structure of the Tsg101 UEV domain in complex with a HIV-1 PTAP "late domain" peptide, DYANA Ensemble
分子名称: Gag Polyprotein, Tumor Susceptibility gene 101 protein
著者Pornillos, O, Alam, S.L, Davis, D.R, Sundquist, W.I.
登録日2002-07-03
公開日2002-11-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein
Nat.Struct.Biol., 9, 2002
1M4Q
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STRUCTURE OF THE TSG101 UEV DOMAIN IN COMPLEX WITH A HIV-1 PTAP "LATE DOMAIN" PEPTIDE, CNS ENSEMBLE
分子名称: Gag Polyprotein, Tumor Susceptibility gene 101 protein
著者Pornillos, O, Alam, S.L, Davis, D.R, Sundquist, W.I.
登録日2002-07-03
公開日2002-11-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein
Nat.Struct.Biol., 9, 2002
2C50
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MS2-RNA HAIRPIN (A -5) COMPLEX
分子名称: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *AP*AP*CP*CP*CP*AP*UP*GP*U)-3', COAT PROTEIN
著者Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L.
登録日2005-10-25
公開日2006-01-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Rna, 7, 2001
2C4Q
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MS2-RNA HAIRPIN (2ONE -5) COMPLEX
分子名称: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *PYO*AP*CP*CP*CP*AP*UP*GP*U)-3', COAT PROTEIN
著者Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L.
登録日2005-10-21
公開日2005-11-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Rna, 7, 2001
2C51
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MS2-RNA HAIRPIN (G -5) COMPLEX
分子名称: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *GP*AP*CP*CP*CP*AP*UP*GP*U)-3', COAT PROTEIN
著者Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L.
登録日2005-10-25
公開日2006-01-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Rna, 7, 2001
2C4Y
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MS2-RNA HAIRPIN (2THIOURACIL-5) COMPLEX
分子名称: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *SUR*AP*CP*CP*CP*AP*UP*GP*U)-3', Capsid protein
著者Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L.
登録日2005-10-25
公開日2006-01-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Rna, 7, 2001
2C4Z
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MS2-RNA HAIRPIN (2SU -5-6) COMPLEX
分子名称: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*SUR *SUR*AP*CP*CP*CP*AP*UP*GP*U)-3', COAT PROTEIN
著者Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L.
登録日2005-10-25
公開日2006-01-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Rna, 7, 2001
2BU1
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MS2-RNA HAIRPIN (5BRU -5) COMPLEX
分子名称: 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *5BU*AP*CP*CP*CP*AP*UP*GP*U)-3', MS2 COAT PROTEIN
著者Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L.
登録日2005-06-08
公開日2005-08-18
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex.
Rna, 7, 2001
1BZ2
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STABILIZATION OF THE ANTICODON STEM-LOOP OF TRNALYS,3 BY AN A+C BASE PAIR AND BY PSEUDOURIDINE, NMR, 1 STRUCTURE
分子名称: TRNA
著者Durant, P.C, Davis, D.R.
登録日1998-11-05
公開日1999-04-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Stabilization of the anticodon stem-loop of tRNALys,3 by an A+-C base-pair and by pseudouridine.
J.Mol.Biol., 285, 1999
1BZT
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STABILIZATION OF THE ANTICODON STEM-LOOP OF TRNALYS,3 BY AN A+C BASE PAIR AND BY PSEUDOURIDINE, NMR, 1 STRUCTURE
分子名称: TRNA
著者Durant, P.C, Davis, D.R.
登録日1998-11-05
公開日1999-04-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Stabilization of the anticodon stem-loop of tRNALys,3 by an A+-C base-pair and by pseudouridine.
J.Mol.Biol., 285, 1999
2LPS
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Molecular dynamics re-refinement of domain 5 of the yeast ai5(gamma) group II intron
分子名称: RNA (34-MER)
著者Henriksen, N.M, Davis, D.R, Cheatham III, T.E.
登録日2012-02-17
公開日2012-08-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Molecular dynamics re-refinement of two different small RNA loop structures using the original NMR data suggest a common structure.
J.Biomol.Nmr, 53, 2012
2LPT
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Molecular dynamics re-refinement of domain 5 of the Pylaiella littoralis group II intron
分子名称: RNA_(34-MER)
著者Henriksen, N.M, Davis, D.R, Cheatham III, T.E.
登録日2012-02-17
公開日2012-08-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Molecular dynamics re-refinement of two different small RNA loop structures using the original NMR data suggest a common structure.
J.Biomol.Nmr, 53, 2012
2KTZ
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Inhibitor Induced Structural Change in the HCV IRES Domain IIa RNA
分子名称: (7R)-7-[(dimethylamino)methyl]-1-[3-(dimethylamino)propyl]-7,8-dihydro-1H-furo[3,2-e]benzimidazol-2-amine, HCV IRES Domain IIa RNA
著者Paulsen, R.B, Seth, P.P, Swayze, E.E, Griffey, R.H, Skalicky, J.J, Cheatham III, T.E, Davis, D.R.
登録日2010-02-10
公開日2010-04-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Inhibitor-induced structural change in the HCV IRES domain IIa RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
1Q5W
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Ubiquitin Recognition by Npl4 Zinc-Fingers
分子名称: Ubiquitin, ZINC ION, homolog of yeast nuclear protein localization 4
著者Alam, S.L, Sun, J, Payne, M, Welch, B.D, Blake, B.K, Davis, D.R, Meyer, H.H, Emr, S.D, Sundquist, W.I.
登録日2003-08-11
公開日2004-03-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Ubiquitin interactions of NZF zinc fingers.
Embo J., 23, 2004

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