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PDB: 12 results

6U7T
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BU of 6u7t by Molmil
MutY adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G)
Descriptor: Adenine DNA glycosylase, CALCIUM ION, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), ...
Authors:O'Shea Murray, V.L, Cao, S, Horvath, M.P, David, S.S.
Deposit date:2019-09-03
Release date:2019-10-02
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY.
Acs Chem.Biol., 15, 2020
6Q0C
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BU of 6q0c by Molmil
MutY adenine glycosylase bound to DNA containing a transition state analog (1N) paired with undamaged dG
Descriptor: 1,2-ETHANEDIOL, A/G-specific adenine glycosylase, CALCIUM ION, ...
Authors:O'Shea Murray, V.L, Russelburg, L.P, Horvath, M.P, David, S.S.
Deposit date:2019-08-01
Release date:2019-08-28
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY.
Acs Chem.Biol., 15, 2020
8DVP
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BU of 8dvp by Molmil
Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with substrate purine
Descriptor: ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ...
Authors:Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S.
Deposit date:2022-07-29
Release date:2022-11-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
8DW0
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BU of 8dw0 by Molmil
Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an enzyme-generated abasic site (AP) product and crystallized with sodium acetate
Descriptor: 1,2-ETHANEDIOL, Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), ...
Authors:Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S.
Deposit date:2022-07-30
Release date:2022-11-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
8DVY
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BU of 8dvy by Molmil
DNA glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an enzyme-generated abasic site product (AP) and crystalized with calcium acetate
Descriptor: ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ...
Authors:Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S.
Deposit date:2022-07-30
Release date:2022-11-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
8DW4
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BU of 8dw4 by Molmil
Glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an abasic site product (AP) generated by the enzyme in crystals by removal of calcium
Descriptor: ACETATE ION, Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), ...
Authors:Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S.
Deposit date:2022-07-31
Release date:2022-11-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
8DW7
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BU of 8dw7 by Molmil
DNA glycosylase MutY variant N146S in complex with DNA containing the transition state analog 1N paired with d(8-oxo-G)
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Adenine DNA glycosylase, ...
Authors:Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S.
Deposit date:2022-07-31
Release date:2022-11-30
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism.
Nucleic Acids Res., 51, 2023
8DWD
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BU of 8dwd by Molmil
Adenine glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with an AP site generated by the enzyme acting on purine
Descriptor: ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ...
Authors:Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P.
Deposit date:2022-08-01
Release date:2023-08-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY
To Be Published
8DWE
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BU of 8dwe by Molmil
Adenine glycosylase MutY variant E43Q in complex with DNA containing d(8-oxo-G) paired with substrate purine
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Adenine DNA glycosylase, ...
Authors:Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P.
Deposit date:2022-08-01
Release date:2023-08-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY
To Be Published
8DWF
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BU of 8dwf by Molmil
Glycosylase MutY variant E43S in complex with DNA containing d(8-oxo-G) paired with substrate adenine
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Adenine DNA glycosylase, ...
Authors:Russelburg, L.P, Demir, M, David, S.S, Horvath, M.P.
Deposit date:2022-08-01
Release date:2023-08-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis for Base Engagement and Stereochemistry Revealed by Alteration of Catalytic Residue Glu43 in DNA Repair Glycosylase MutY
To Be Published
1KQJ
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BU of 1kqj by Molmil
Crystal Structure of a Mutant of MutY Catalytic Domain
Descriptor: A/G-SPECIFIC ADENINE GLYCOSYLASE, GLYCEROL, IRON/SULFUR CLUSTER, ...
Authors:Messick, T.E, Chmiel, N.H, Golinelli, M.P, David, S.S, Joshua-Tor, L.
Deposit date:2002-01-06
Release date:2002-04-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster.
Biochemistry, 41, 2002
8FAY
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BU of 8fay by Molmil
Human MUTYH adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G)
Descriptor: Adenine DNA glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*CP*AP*(NR1)P*GP*TP*CP*T)-3'), ...
Authors:Trasvina-Arenas, C.H, Lin, W.J, Demir, M, Fisher, A.J, David, S.S, Horvath, M.P.
Deposit date:2022-11-29
Release date:2024-05-29
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Human MUTYH adenine glycosylase bound to DNA containing a transition state analog (1N) paired with d(8-oxo-G)
To Be Published

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PDB entries from 2024-07-17

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