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PDB: 7 results

6ES0
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BU of 6es0 by Molmil
Crystal structure of the kinase domain of human RIPK2 in complex with the activation loop targeting inhibitor CS-R35
Descriptor: 2-[2-fluoranyl-4-[[2-fluoranyl-4-[2-(methylcarbamoyl)pyridin-4-yl]oxy-phenyl]carbamoylamino]phenyl]sulfanylethanoic acid, Receptor-interacting serine/threonine-protein kinase 2
Authors:Pinkas, D.M, Bufton, J.C, Suebsuwong, C, Ray, S.S, Dai, B, Newman, J.A, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Degterev, A, Cuny, G.D, Bullock, A.N.
Deposit date:2017-10-19
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors.
Bioorg. Med. Chem. Lett., 28, 2018
8IKP
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BU of 8ikp by Molmil
Cryo-EM structure of hnRAC1-8I fibril
Descriptor: GLY-PHE-GLY-GLY-ASN-ASP-ASN-PHI-GLY
Authors:Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
Deposit date:2023-02-28
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Cryo-EM structure of hnRAC1-8I fibril
To Be Published
8IK7
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BU of 8ik7 by Molmil
Cryo-EM structure of hnRAC1 fibril.
Descriptor: GLY-PHE-GLY-GLY-ASN-ASP-ASN-PHE-GLY
Authors:Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
Deposit date:2023-02-28
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Formed fibrils of hnRNP A1 reversible amyloid core GFGGNDNFG (residues 209-217)
To Be Published
8IKS
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BU of 8iks by Molmil
Cryo-EM structure of hnRAC1-2I8I fibril.
Descriptor: GLY-PHI-GLY-GLY-ASN-ASP-ASN-PHI-GLY
Authors:Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
Deposit date:2023-03-01
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Cryo-EM structure of hnRAC1-2I8I fibril.
To Be Published
8IY7
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BU of 8iy7 by Molmil
Cryo-EM structure of DIP-2I8I fibril polymorph1
Descriptor: GLY-PHI-GLY-ASN-GLY-ASN-GLY-PHI-GLY
Authors:Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
Deposit date:2023-04-04
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Cryo-EM structure of DIP-2I8I fibril polymorph1
To Be Published
8IZZ
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BU of 8izz by Molmil
Cryo-EM structure of DIP-2I8I polymorph 2
Descriptor: GLY-PHI-GLY-ASN-GLY-ASN-GLY-PHI-GLY
Authors:Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
Deposit date:2023-04-09
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Cryo-EM structure of DIP-2I8I fibril polymorph 2
To Be Published
8IKB
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BU of 8ikb by Molmil
Cryo-EM structure of hnRAC1-2I fibril.
Descriptor: GLY-PHI-GLY-GLY-ASN-ASP-ASN-PHE-GLY
Authors:Li, D.N, Ma, Y.Y, Li, D, Dai, B, Liu, C.
Deposit date:2023-02-28
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Cryo-EM structure of hnRAC1-2I fibril.
To Be Published

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PDB entries from 2024-06-05

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