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PDB: 1607 results

7JUN
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BU of 7jun by Molmil
Joint neutron/X-ray structure of SARS-CoV-2 3CL Mpro at room temperature
Descriptor: 3C-like proteinase
Authors:Kovalevsky, A, Kneller, D.W, Coates, L.
Deposit date:2020-08-20
Release date:2020-09-02
Last modified:2024-04-03
Method:NEUTRON DIFFRACTION (2.3 Å), X-RAY DIFFRACTION
Cite:Unusual zwitterionic catalytic site of SARS-CoV-2 main protease revealed by neutron crystallography.
J.Biol.Chem., 295, 2020
2IDR
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BU of 2idr by Molmil
Crystal structure of translation initiation factor EIF4E from wheat
Descriptor: Eukaryotic translation initiation factor 4E-1
Authors:Monzingo, A.F, Sadow, J, Dhaliwal, S, Lyon, A, Hoffman, D.W, Robertus, J.D, Browning, K.S.
Deposit date:2006-09-15
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The structure of eukaryotic translation initiation factor-4E from wheat reveals a novel disulfide bond.
Plant Physiol., 143, 2007
2IJD
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BU of 2ijd by Molmil
Crystal Structure of the Poliovirus Precursor Protein 3CD
Descriptor: Picornain 3C, RNA-directed RNA polymerase, SULFATE ION, ...
Authors:Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M.
Deposit date:2006-09-29
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of poliovirus 3CD: virally-encoded protease and precursor to the RNA-dependent RNA polymerase.
J.Virol., 81, 2007
2ILU
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BU of 2ilu by Molmil
Crystal structure of lactaldehyde dehydrogenase from E. coli: the binary complex with NADPH
Descriptor: Aldehyde dehydrogenase A, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION
Authors:Di Costanzo, L, Gomez, G, Christianson, D.W.
Deposit date:2006-10-03
Release date:2007-05-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of lactaldehyde dehydrogenase from Escherichia coli and inferences regarding substrate and cofactor specificity.
J.Mol.Biol., 366, 2007
2J7Z
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BU of 2j7z by Molmil
Crystal Structure of recombinant Human Stromal Cell-Derived Factor- 1alpha
Descriptor: STROMAL CELL-DERIVED FACTOR 1 ALPHA
Authors:Ryu, E.K, Kim, T.G, Kwon, T.H, Jung, I.D, Ryu, D.W, Park, Y.-M, Ahn, K, Ban, C.
Deposit date:2006-10-18
Release date:2006-10-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of Recombinant Human Stromal Cell-Derived Factor-1Alpha.
Proteins, 67, 2007
2IDV
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BU of 2idv by Molmil
Crystal structure of wheat C113S mutant EIF4E bound TO 7-methyl-GDP
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic translation initiation factor 4E-1
Authors:Monzingo, A.F, Dutt-Chaudhuri, A, Sadow, J, Dhaliwal, S, Hoffman, D.W, Robertus, J.D, Browning, K.S.
Deposit date:2006-09-15
Release date:2007-06-12
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of eukaryotic translation initiation factor-4E from wheat reveals a novel disulfide bond.
Plant Physiol., 143, 2007
2IER
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BU of 2ier by Molmil
Crystal Structure of Aquifex aeolicus LpxC Complexed with Uridine 5'-Diphosphate
Descriptor: GLYCEROL, PALMITIC ACID, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ...
Authors:Gennadios, H.A, Christianson, D.W.
Deposit date:2006-09-19
Release date:2007-01-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Binding of Uridine 5-Diphosphate in the Basic Patch of the Zinc Metalloenzyme Deacetylase LpxC and Implications for Substrate Binding
Biochemistry, 45, 2006
2F2G
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BU of 2f2g by Molmil
X-Ray Structure of Gene Product From Arabidopsis Thaliana AT3G16990
Descriptor: 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, SEED MATURATION PROTEIN PM36 HOMOLOG, SULFATE ION
Authors:Wesenberg, G.W, Smith, D.W, Phillips Jr, G.N, Johnson, K.A, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2005-11-16
Release date:2005-12-13
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of gene locus At3g16990 from Arabidopsis thaliana
Proteins, 57, 2004
2JDA
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BU of 2jda by Molmil
Structure of a pectin binding carbohydrate binding module determined in an monoclinic crystal form.
Descriptor: CALCIUM ION, GLYCEROL, SULFATE ION, ...
Authors:Abbott, D.W, Boraston, A.B.
Deposit date:2007-01-05
Release date:2007-01-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Identification and Characterization of a Novel Periplasmic Polygalacturonic Acid Binding Protein from Yersinia Enterolitica
J.Mol.Biol., 367, 2007
2JTP
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BU of 2jtp by Molmil
Solution Structure of the Frameshift-Inducing RNA Stem-Loop in SIV
Descriptor: SIV17-50 RNA (34-MER)
Authors:Marcheschi, R.J, Staple, D.W, Butcher, S.E.
Deposit date:2007-08-04
Release date:2007-10-02
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Programmed Ribosomal Frameshifting in SIV Is Induced by a Highly Structured RNA Stem-Loop
J.Mol.Biol., 373, 2007
2JKH
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BU of 2jkh by Molmil
Factor Xa - cation inhibitor complex
Descriptor: 3-[(3~{a}~{S},4~{R},8~{a}~{S},8~{b}~{R})-4-[5-(5-chloranylthiophen-2-yl)-1,2-oxazol-3-yl]-1,3-bis(oxidanylidene)-4,6,7,8,8~{a},8~{b}-hexahydro-3~{a}~{H}-pyrrolo[3,4-a]pyrrolizin-2-yl]propyl-trimethyl-azanium, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ...
Authors:Salonen, L.M, Bucher, C, Banner, D.W, Benz, J, Haap, W, Mary, J.L, Schweizer, W.B, Seiler, P, Kuster, O, Diederich, F.
Deposit date:2008-08-28
Release date:2009-01-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Cation-Pi Interactions at the Active Site of Factor Xa: Dramatic Enhancement Upon Stepwise N-Alkylation of Ammonium Ions.
Angew.Chem.Int.Ed.Engl., 48, 2009
3KB9
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BU of 3kb9 by Molmil
Epi-isozizaene synthase: Complex with Mg, inorganic pyrophosphate and benzyl triethyl ammonium cation
Descriptor: Epi-isozizaene synthase, GLYCEROL, MAGNESIUM ION, ...
Authors:Aaron, J.A, Lin, X, Cane, D.E, Christianson, D.W.
Deposit date:2009-10-20
Release date:2010-02-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.598 Å)
Cite:Structure of Epi-Isozizaene Synthase from Streptomyces coelicolor A3(2), a Platform for New Terpenoid Cyclization Templates
Biochemistry, 49, 2010
7ROR
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BU of 7ror by Molmil
Plasmodium falciparum tyrosyl-tRNA synthetase in complex with tyrosine-AMP
Descriptor: 5'-O-[(S)-{[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]oxy}(hydroxy)phosphoryl]adenosine, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W.
Deposit date:2021-08-02
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy.
Science, 376, 2022
7ROS
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BU of 7ros by Molmil
Plasmodium falciparum tyrosyl-tRNA synthetase in complex with ML901-Tyr
Descriptor: CHLORIDE ION, MAGNESIUM ION, Tyrosine--tRNA ligase, ...
Authors:Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W.
Deposit date:2021-08-02
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy.
Science, 376, 2022
7ROU
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BU of 7rou by Molmil
Structure of human tyrosyl tRNA synthetase in complex with ML901-Tyr
Descriptor: SULFATE ION, Tyrosine--tRNA ligase, cytoplasmic, ...
Authors:Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W.
Deposit date:2021-08-02
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy.
Science, 376, 2022
7ROT
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BU of 7rot by Molmil
Plasmodium falciparum tyrosyl-tRNA synthetase, S234C mutant, in complex with ML901-Tyr
Descriptor: CHLORIDE ION, MAGNESIUM ION, Tyrosine--tRNA ligase, ...
Authors:Metcalfe, R.D, Xie, S.C, Morton, C.J, Tilley, L, Griffin, M.D.W.
Deposit date:2021-08-02
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy.
Science, 376, 2022
3L25
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BU of 3l25 by Molmil
Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA
Descriptor: CHLORIDE ION, FORMIC ACID, GLYCEROL, ...
Authors:Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K.
Deposit date:2009-12-14
Release date:2010-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Nat.Struct.Mol.Biol., 17, 2010
3KV2
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BU of 3kv2 by Molmil
HIGH RESOLUTION STRUCTURE OF HUMAN ARGINASE I IN COMPLEX WITH THE STRONG INHIBITOR N(omega)-hydroxy-nor-L-arginine (nor-NOHA)
Descriptor: Arginase-1, MANGANESE (II) ION, NOR-N-OMEGA-HYDROXY-L-ARGININE
Authors:Di Costanzo, L, Christianson, D.W.
Deposit date:2009-11-28
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Inhibition of human arginase I by substrate and product analogues.
Arch.Biochem.Biophys., 496, 2010
3L28
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BU of 3l28 by Molmil
Crystal structure of Zaire Ebola VP35 interferon inhibitory domain K339A mutant
Descriptor: CHLORIDE ION, Polymerase cofactor VP35, SODIUM ION, ...
Authors:Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K.
Deposit date:2009-12-14
Release date:2010-01-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Nat.Struct.Mol.Biol., 17, 2010
7CXO
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BU of 7cxo by Molmil
Crystal structure of Arabinose isomerase from hybrid AI10
Descriptor: GLYCEROL, L-arabinose isomerase, MANGANESE (II) ION
Authors:Hoang, N.K.Q, Dhanasingh, I, Cao, T.P, Sung, J.Y, Shin, S.M, Lee, D.W, Lee, S.H.
Deposit date:2020-09-02
Release date:2021-09-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of Arabinose isomerase from hyper thermophilic hybrid AI10
To Be Published
7CYY
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BU of 7cyy by Molmil
Crystal structure of Arabinose isomerase from hybrid AI8 with Adonitol
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, D-ribitol, L-arabinose isomerase, ...
Authors:Hoang, N.K.Q, Dhanasingh, I, Cao, T.P, Sung, J.Y, Shin, S.M, Lee, D.W, Lee, S.H.
Deposit date:2020-09-05
Release date:2021-09-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Arabinose isomerase from hyper thermophilic hybrid AI8 with Adonitol
To Be Published
7S4B
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BU of 7s4b by Molmil
Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound Z1530724963
Descriptor: (2R)-2-(3-fluorophenyl)-N-(isoquinolin-4-yl)propanamide, 3C-like proteinase
Authors:Kovalevsky, A, Kneller, D.W, Coates, L.
Deposit date:2021-09-08
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hit Expansion of a Noncovalent SARS-CoV-2 Main Protease Inhibitor.
Acs Pharmacol Transl Sci, 5, 2022
7S3S
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BU of 7s3s by Molmil
Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound Z1530724813
Descriptor: 2-(3-chlorophenyl)-N-(isoquinolin-4-yl)acetamide, 3C-like proteinase
Authors:Kovalevsky, A, Kneller, D.W, Coates, L.
Deposit date:2021-09-08
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hit Expansion of a Noncovalent SARS-CoV-2 Main Protease Inhibitor.
Acs Pharmacol Transl Sci, 5, 2022
3L29
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BU of 3l29 by Molmil
Crystal Structure of Zaire Ebola VP35 interferon inhibitory domain K319A/R322A mutant
Descriptor: CHLORIDE ION, Polymerase cofactor VP35
Authors:Leung, D.W, Ramanan, P, Borek, D.M, Amarasinghe, G.K.
Deposit date:2009-12-14
Release date:2010-02-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mutations abrogating VP35 interaction with double-stranded RNA render ebola virus avirulent in guinea pigs.
J.Virol., 84, 2010
7S3K
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BU of 7s3k by Molmil
Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound Z1530718726
Descriptor: 2-(5-chloro-2-methoxyphenyl)-N-(isoquinolin-4-yl)acetamide, 3C-like proteinase
Authors:Kovalevsky, A, Kneller, D.W, Coates, L.
Deposit date:2021-09-07
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Hit Expansion of a Noncovalent SARS-CoV-2 Main Protease Inhibitor.
Acs Pharmacol Transl Sci, 5, 2022

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