1W2Z
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![BU of 1w2z by Molmil](/molmil-images/mine/1w2z) | PSAO and Xenon | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AMINE OXIDASE, COPPER CONTAINING, ... | 著者 | Duff, A.P, Trambaiolo, D.M, Cohen, A.E, Ellis, P.J, Juda, G.A, Shepard, E.M, Langley, D.B, Dooley, D.M, Freeman, H.C, Guss, J.M. | 登録日 | 2004-07-11 | 公開日 | 2004-11-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Using Xenon as a Probe for Dioxygen-Binding Sites in Copper Amine Oxidases. J.Mol.Biol., 344, 2004
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7Z6C
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![BU of 7z6c by Molmil](/molmil-images/mine/7z6c) | Crystal structure of human Dihydroorotate Dehydrogenase in complex with the inhibitor 2-Hydroxy-N-(2-ispropyl-5-methyl-4-phenoxyphenyl)pyrazolo[1,5-a]pyridine-3-carboxamide. | 分子名称: | ACETATE ION, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | 著者 | Alberti, M, Lolli, M.L, Boschi, D, Sainas, S, Rizzi, M, Ferraris, D.M, Miggiano, R. | 登録日 | 2022-03-11 | 公開日 | 2022-10-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a ]pyridine Scaffold: SAR of the Aryloxyaryl Moiety. J.Med.Chem., 65, 2022
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1M7Q
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![BU of 1m7q by Molmil](/molmil-images/mine/1m7q) | Crystal structure of p38 MAP kinase in complex with a dihydroquinazolinone inhibitor | 分子名称: | 1-(2,6-DICHLOROPHENYL)-5-(2,4-DIFLUOROPHENYL)-7-PIPERAZIN-1-YL-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE, Mitogen-activated protein kinase 14, SULFATE ION | 著者 | Stelmach, J.E, Liu, L, Patel, S.B, Pivnichny, J.V, Scapin, G, Singh, S, Hop, C.E.C.A, Wang, Z, Cameron, P.M, Nichols, E.A, O'Keefe, S.J, O'Neill, E.A, Schmatz, D.M, Schwartz, C.D, Thompson, C.M, Zaller, D.M, Doherty, J.B. | 登録日 | 2002-07-22 | 公開日 | 2002-12-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Design and synthesis of potent, orally bioavailable dihydroquinazolinone inhibitors of p38 MAP kinase. Bioorg.Med.Chem.Lett., 13, 2003
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6QZL
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![BU of 6qzl by Molmil](/molmil-images/mine/6qzl) | Structure of the H1 domain of human KCTD12 | 分子名称: | BTB/POZ domain-containing protein KCTD12 | 著者 | Pinkas, D.M, Bufton, J.C, Fox, A.E, Newman, J.A, Kupinska, K, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N, Structural Genomics Consortium (SGC) | 登録日 | 2019-03-11 | 公開日 | 2019-03-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structure of the H1 domain of human KCTD12 To be published
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4URJ
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![BU of 4urj by Molmil](/molmil-images/mine/4urj) | Crystal structure of human BJ-TSA-9 | 分子名称: | 1,2-ETHANEDIOL, PROTEIN FAM83A | 著者 | Pinkas, D.M, Sanvitale, C, Wang, D, Krojer, T, Kopec, J, Chaikuad, A, Dixon Clarke, S, Berridge, G, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Bullock, A. | 登録日 | 2014-06-30 | 公開日 | 2014-10-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Crystal Structure of Human Bj-Tsa-9 To be Published
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6L4C
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6L89
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![BU of 6l89 by Molmil](/molmil-images/mine/6l89) | Human PPARgamma ligand binding domain complexed with Butyrolactone 1 | 分子名称: | Peroxisome proliferator-activated receptor gamma, methyl (2R)-3-(4-hydroxyphenyl)-2-[[3-(3-methylbut-2-enyl)-4-oxidanyl-phenyl]methyl]-4-oxidanyl-5-oxidanylidene-furan-2-carboxylate | 著者 | Jang, D.M, Han, B.W. | 登録日 | 2019-11-05 | 公開日 | 2020-09-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Cyclin-Dependent Kinase 5 Inhibitor Butyrolactone I Elicits a Partial Agonist Activity of Peroxisome Proliferator-Activated Receptor gamma. Biomolecules, 10, 2020
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8JSB
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![BU of 8jsb by Molmil](/molmil-images/mine/8jsb) | |
6D71
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![BU of 6d71 by Molmil](/molmil-images/mine/6d71) | Crystal Structure of the Human Miro1 N-terminal GTPase bound to GTP | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial Rho GTPase 1 | 著者 | Smith, K.P, Focia, P.J, Rice, S.E, Freymann, D.M. | 登録日 | 2018-04-23 | 公開日 | 2019-10-09 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.7180779 Å) | 主引用文献 | Insight into human Miro1/2 domain organization based on the structure of its N-terminal GTPase. J.Struct.Biol., 212, 2020
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6WS0
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![BU of 6ws0 by Molmil](/molmil-images/mine/6ws0) | |
2KZG
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![BU of 2kzg by Molmil](/molmil-images/mine/2kzg) | A Transient and Low Populated Protein Folding Intermediate at Atomic Resolution | 分子名称: | Pre-mRNA-processing factor 40 homolog A | 著者 | Korzhnev, D.M, Religa, T.L, Banachewicz, W, Fersht, A.R, Kay, L.E. | 登録日 | 2010-06-17 | 公開日 | 2010-09-29 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | A transient and low-populated protein-folding intermediate at atomic resolution. Science, 329, 2010
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2LKS
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![BU of 2lks by Molmil](/molmil-images/mine/2lks) | Ff11-60 | 分子名称: | Pre-mRNA-processing factor 40 homolog A | 著者 | Barette, J, Velyvis, A, Religa, T.L, Korzhnev, D.M, Kay, L.E. | 登録日 | 2011-10-19 | 公開日 | 2012-01-11 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Cross-Validation of the Structure of a Transiently Formed and Low Populated FF Domain Folding Intermediate Determined by Relaxation Dispersion NMR and CS-Rosetta. J.Phys.Chem.B, 116, 2012
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2L0Q
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![BU of 2l0q by Molmil](/molmil-images/mine/2l0q) | NMR Solution Structure of Vibrio harveyi Acyl Carrier Protein (ACP) | 分子名称: | Acyl carrier protein | 著者 | Chan, D.I, Chu, B.C.H, Lau, C.K.Y, Hunter, H.N, Byers, D.M, Vogel, H.J. | 登録日 | 2010-07-12 | 公開日 | 2010-07-21 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure and biophysical characterization of Vibrio harveyi acyl carrier protein A75H: effects of divalent metal ions. J.Biol.Chem., 285, 2010
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2L9V
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![BU of 2l9v by Molmil](/molmil-images/mine/2l9v) | NMR structure of the FF domain L24A mutant's folding transition state | 分子名称: | Pre-mRNA-processing factor 40 homolog A | 著者 | Korzhnev, D.M, Vernon, R.M, Religa, T.L, Hansen, A, Baker, D, Fersht, A.R, Kay, L.E. | 登録日 | 2011-02-24 | 公開日 | 2011-09-28 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Nonnative interactions in the FF domain folding pathway from an atomic resolution structure of a sparsely populated intermediate: an NMR relaxation dispersion study. J.Am.Chem.Soc., 133, 2011
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5NJF
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![BU of 5njf by Molmil](/molmil-images/mine/5njf) | E. coli Microcin-processing metalloprotease TldD/E (TldD H262A mutant) with pentapeptide bound | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ALA-ALA-ALA-ALA-ALA, ... | 著者 | Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K. | 登録日 | 2017-03-28 | 公開日 | 2017-10-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | The Origins of Specificity in the Microcin-Processing Protease TldD/E. Structure, 25, 2017
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5NJB
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![BU of 5njb by Molmil](/molmil-images/mine/5njb) | E. coli Microcin-processing metalloprotease TldD/E with actinonin bound | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACTINONIN, ... | 著者 | Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K. | 登録日 | 2017-03-28 | 公開日 | 2017-10-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The Origins of Specificity in the Microcin-Processing Protease TldD/E. Structure, 25, 2017
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5NJC
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![BU of 5njc by Molmil](/molmil-images/mine/5njc) | E. coli Microcin-processing metalloprotease TldD/E (TldD E263A mutant) with hexapeptide bound | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Metalloprotease PmbA, ... | 著者 | Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K. | 登録日 | 2017-03-28 | 公開日 | 2017-10-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | The Origins of Specificity in the Microcin-Processing Protease TldD/E. Structure, 25, 2017
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5NJA
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![BU of 5nja by Molmil](/molmil-images/mine/5nja) | E. coli Microcin-processing metalloprotease TldD/E with angiotensin analogue bound | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HIS-PRO-PHE, ... | 著者 | Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K. | 登録日 | 2017-03-28 | 公開日 | 2017-10-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The Origins of Specificity in the Microcin-Processing Protease TldD/E. Structure, 25, 2017
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5HGE
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![BU of 5hge by Molmil](/molmil-images/mine/5hge) | Filamentous Assembly of Green Fluorescent Protein Supported by a C-terminal fusion of 18-residues, viewed in space group P212121 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Green fluorescent protein | 著者 | Sawaya, M.R, Heller, D.M, McPartland, L, Hochschild, A, Eisenberg, D.S. | 登録日 | 2016-01-08 | 公開日 | 2017-01-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.863 Å) | 主引用文献 | Green Fluorescent Protein Fusion that Self Assembles as Polar Filaments to be published
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5HID
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![BU of 5hid by Molmil](/molmil-images/mine/5hid) | BRAF Kinase domain b3aC loop deletion mutant in complex with AZ628 | 分子名称: | 3-(2-cyanopropan-2-yl)-N-{4-methyl-3-[(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}benzamide, DI(HYDROXYETHYL)ETHER, Serine/threonine-protein kinase B-raf | 著者 | Whalen, D.M, Foster, S.A, Ozen, A, Wongchenko, M, Yin, J, Schaefer, G, Mayfield, J, Chmielecki, J, Stephens, P, Albacker, L, Yan, Y, Song, K, Hatzivassiliou, G, Eigenbrot, C, Yu, C, Shaw, A.S, Manning, G, Skelton, N.J, Hymowitz, S.G, Malek, S. | 登録日 | 2016-01-11 | 公開日 | 2016-04-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2. Cancer Cell, 29, 2016
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3L28
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![BU of 3l28 by Molmil](/molmil-images/mine/3l28) | Crystal structure of Zaire Ebola VP35 interferon inhibitory domain K339A mutant | 分子名称: | CHLORIDE ION, Polymerase cofactor VP35, SODIUM ION, ... | 著者 | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | 登録日 | 2009-12-14 | 公開日 | 2010-01-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35. Nat.Struct.Mol.Biol., 17, 2010
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3L27
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![BU of 3l27 by Molmil](/molmil-images/mine/3l27) | Crystal structure of Zaire Ebola VP35 interferon inhibitory domain R312A mutant | 分子名称: | CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... | 著者 | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | 登録日 | 2009-12-14 | 公開日 | 2010-01-26 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35. Nat.Struct.Mol.Biol., 17, 2010
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3L26
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![BU of 3l26 by Molmil](/molmil-images/mine/3l26) | Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Polymerase cofactor VP35, ... | 著者 | Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K. | 登録日 | 2009-12-14 | 公開日 | 2010-01-26 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35. Nat.Struct.Mol.Biol., 17, 2010
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3UBX
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![BU of 3ubx by Molmil](/molmil-images/mine/3ubx) | Crystal structure of the mouse CD1d-C20:2-aGalCer-L363 mAb Fab complex | 分子名称: | (11Z,14Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yu, E.D, Zajonc, D.M. | 登録日 | 2011-10-25 | 公開日 | 2011-11-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for the recognition of C20:2-alpha GalCer by the invariant natural killer T cell receptor-like antibody L363. J.Biol.Chem., 287, 2012
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7MRJ
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![BU of 7mrj by Molmil](/molmil-images/mine/7mrj) | Crystal structure of a novel ubiquitin-like TINCR | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | 著者 | Forouhar, F, Morgado-Palacin, L, Brown, J.A, Martinez, T, Pedrero, J.M.G, Reglero, C, Chaudhry, I, Vaughan, J, Rodriguez-Perales, S, Allonca, E, Granda-Diaz, R, Quinn, S.A, Fernandez, A.F, Fraga, M.F, Kim, A.L, Santos-Juanes, J, Owens, D.M, Rodrigo, J.P, Saghatelian, A, Ferrando, A.A. | 登録日 | 2021-05-07 | 公開日 | 2022-03-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma. Nat Commun, 14, 2023
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