7MRJ

Crystal structure of a novel ubiquitin-like TINCR

Summary for 7MRJ

• Entry DOI: 10.2210/pdb7mrj/pdb
• Descriptor: Ubiquitin domain-containing protein TINCR, GLYCEROL, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: novel ubiquitin-like protein, unknown function
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 24275.95

Authors

Forouhar, F.,Morgado-Palacin, L.,Brown, J.A.,Martinez, T.,Pedrero, J.M.G.,Reglero, C.,Chaudhry, I.,Vaughan, J.,Rodriguez-Perales, S.,Allonca, E.,Granda-Diaz, R.,Quinn, S.A.,Fernandez, A.F.,Fraga, M.F.,Kim, A.L.,Santos-Juanes, J.,Owens, D.M.,Rodrigo, J.P.,Saghatelian, A.,Ferrando, A.A. (deposition date: 2021-05-07, release date: 2022-03-16, Last modification date: 2023-10-25)

• Primary citation: Morgado-Palacin, L.,Brown, J.A.,Martinez, T.F.,Garcia-Pedrero, J.M.,Forouhar, F.,Quinn, S.A.,Reglero, C.,Vaughan, J.,Heydary, Y.H.,Donaldson, C.,Rodriguez-Perales, S.,Allonca, E.,Granda-Diaz, R.,Fernandez, A.F.,Fraga, M.F.,Kim, A.L.,Santos-Juanes, J.,Owens, D.M.,Rodrigo, J.P.,Saghatelian, A.,Ferrando, A.A.; The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma.; Nat Commun, 14:1328-1328, 2023; PubMed: 36899004; DOI: 10.1038/s41467-023-36713-8

Experimental method

X-RAY DIFFRACTION (2.12 Å)