6EZJ
| Imidazoleglycerol-phosphate dehydratase | 分子名称: | Imidazoleglycerol-phosphate dehydratase 2, chloroplastic, MANGANESE (II) ION, ... | 著者 | Rawson, S, Bisson, C, Hurdiss, D.L, Muench, S.P. | 登録日 | 2017-11-15 | 公開日 | 2018-02-07 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6FP4
| Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 1,8-Naphthyridine-2-carboxylic acid | 分子名称: | (2R)-2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid, 1,8-naphthyridine-2-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Silvestri, I, Fata, F, MIele, A.E, Boumis, G, Williams, D.L, Angelucci, F. | 登録日 | 2018-02-09 | 公開日 | 2018-06-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. ACS Chem. Biol., 13, 2018
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6FTC
| Thioredoxin glutathione reductase from Schistosoma mansoni in complex with HEPES | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Silvestri, I, Fata, F, MIele, A.E, Boumis, G, Williams, D.L, Angelucci, F. | 登録日 | 2018-02-21 | 公開日 | 2018-06-06 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. ACS Chem. Biol., 13, 2018
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6FMU
| Thioredoxin glutathione reductase from Schistosome mansoni in complex with 2-[4-(4-amino-butyl)-piperazin-1-yl]-ethanol | 分子名称: | 2-[4-(4-azanylbutyl)piperazin-1-yl]ethanol, FLAVIN-ADENINE DINUCLEOTIDE, TRIETHYLENE GLYCOL, ... | 著者 | Silvestri, I, Fata, F, MIele, A.E, Boumis, G, Williams, D.L, Angelucci, F. | 登録日 | 2018-02-02 | 公開日 | 2018-06-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. ACS Chem. Biol., 13, 2018
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6FMZ
| Thioredoxin glutathione reductase from Schistosoma mansoni in complex with 1,4-Bis(2-hydroxyethyl)piperazine | 分子名称: | 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanol, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase | 著者 | Silvestri, I, Fata, F, MIele, A.E, Boumis, G, Williams, D.L, Angelucci, F. | 登録日 | 2018-02-02 | 公開日 | 2018-06-06 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as "Doorstop" for NADPH Entry. ACS Chem. Biol., 13, 2018
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6E3Y
| Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor | 分子名称: | Calcitonin gene-related peptide 1, Calcitonin gene-related peptide type 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Liang, Y.L, Khoshouei, M, Deganutti, G, Glukhova, A, Koole, C, Peat, T.S, Radjainia, M, Plitzko, J.M, Baumeister, W, Miller, L.J, Hay, D.L, Christopoulos, A, Reynolds, C.A, Wootten, D, Sexton, P.M. | 登録日 | 2018-07-16 | 公開日 | 2018-09-19 | 最終更新日 | 2020-01-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor. Nature, 561, 2018
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4EW3
| The structure of human glycinamide ribonucleotide transformylase in complex with 10R-methylthio-DDATHF. | 分子名称: | N-({4-[(1R)-4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-(methylsulfanyl)butyl]phenyl}carbonyl)-L-glutamic acid, PHOSPHATE ION, SULFATE ION, ... | 著者 | Connelly, S, DeMartino, K, Boger, D.L, Wilson, I.A. | 登録日 | 2012-04-26 | 公開日 | 2013-07-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | 主引用文献 | Biological and Structural Evaluation of 10R- and 10S-Methylthio-DDACTHF Reveals a New Role for Sulfur in Inhibition of Glycinamide Ribonucleotide Transformylase. Biochemistry, 52, 2013
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7P0X
| Crystal structure of Thioredoxin reductase from Brugia Malayi | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Fata, F, Ardini, M, Silvestri, I, Gabriele, F, Cheng, Q, Arner, E.S.J, Williams, D.L. | 登録日 | 2021-06-30 | 公開日 | 2022-04-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus. Redox Biol, 51, 2022
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4EW2
| The structure of human glycinamide ribonucleotide transformylase in complex with 10S-methylthio-DDATHF. | 分子名称: | N-({4-[(1S)-4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-(methylsulfanyl)butyl]phenyl}carbonyl)-L-glutamic acid, PHOSPHATE ION, SULFATE ION, ... | 著者 | Connelly, S, DeMartino, K, Boger, D.L, Wilson, I.A. | 登録日 | 2012-04-26 | 公開日 | 2013-07-31 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.602 Å) | 主引用文献 | Biological and Structural Evaluation of 10R- and 10S-Methylthio-DDACTHF Reveals a New Role for Sulfur in Inhibition of Glycinamide Ribonucleotide Transformylase. Biochemistry, 52, 2013
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7PVJ
| Crystal structure of Thioredoxin Reductase from Brugia Malayi in complex with auranofin | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Fata, F, Ardini, M, Silvestri, I, Gabriele, F, Ippoliti, R, Gencheva, R, Cheng, Q, Arner, E.S.J, Angelucci, F, Williams, D.L. | 登録日 | 2021-10-04 | 公開日 | 2022-04-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus. Redox Biol, 51, 2022
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7PUT
| Crystal structure of Thioredoxin Reductase from Brugia Malayi in complex with NADP(H) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Fata, F, Ardini, M, Silvestri, I, Gabriele, F, Ippoliti, R, Gencheva, R, Cheng, Q, Arner, E.S.J, Angelucci, F, Williams, D.L. | 登録日 | 2021-09-30 | 公開日 | 2022-04-06 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus. Redox Biol, 51, 2022
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7PNM
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7PO5
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7PNQ
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2BPN
| SOLUTION STRUCTURE OF DESULFOVIBRIO VULGARIS (HILDENBOROUGH) FERRICYTOCHROME C3, NMR, 20 STRUCTURES | 分子名称: | CYTOCHROME C3, HEME C | 著者 | Messias, A.C, Aguiar, A.P, Brennan, L, Xavier, A.V, Turner, D.L. | 登録日 | 2005-04-21 | 公開日 | 2006-03-15 | 最終更新日 | 2024-10-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structures of Tetrahaem Ferricytochrome C(3) from Desulfovibrio Vulgaris (Hildenborough) and its K45Q Mutant: The Molecular Basis of Cooperativity. Biochim.Biophys.Acta, 1757, 2006
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7QPA
| Outward-facing auxin bound form of auxin transporter PIN8 | 分子名称: | 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1H-INDOL-3-YLACETIC ACID, Auxin efflux carrier component 8 | 著者 | Ung, K.L, Winkler, M.B.L, Dedic, E, Stokes, D.L, Pedersen, B.P. | 登録日 | 2022-01-03 | 公開日 | 2022-07-06 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Structures and mechanism of the plant PIN-FORMED auxin transporter. Nature, 609, 2022
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7QP9
| Outward-facing apo-form of auxin transporter PIN8 | 分子名称: | 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Auxin efflux carrier component 8 | 著者 | Ung, K.L, Winkler, M.B.L, Dedic, E, Stokes, D.L, Pedersen, B.P. | 登録日 | 2022-01-03 | 公開日 | 2022-07-06 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Structures and mechanism of the plant PIN-FORMED auxin transporter. Nature, 609, 2022
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7QPC
| Inward-facing NPA bound form of auxin transporter PIN8 | 分子名称: | 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(naphthalen-1-ylcarbamoyl)benzoic acid, Auxin efflux carrier component 8 | 著者 | Ung, K.L, Winkler, M.B.L, Dedic, E, Stokes, D.L, Pedersen, B.P. | 登録日 | 2022-01-03 | 公開日 | 2022-07-06 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Structures and mechanism of the plant PIN-FORMED auxin transporter. Nature, 609, 2022
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4HCA
| DNA binding by GATA transcription factor-complex 1 | 分子名称: | DNA (5'-D(*AP*AP*TP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*A)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ... | 著者 | Chen, Y, Bates, D.L, Dey, R, Chen, L. | 登録日 | 2012-09-28 | 公開日 | 2012-12-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation. Cell Rep, 2, 2012
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4F12
| Crystal structure of the extracellular domain of human GABA(B) receptor GBR2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 2 | 著者 | Geng, Y, Xiong, D, Mosyak, L, Malito, D.L, Kniazeff, J, Chen, Y, Burmakina, S, Quick, M, Bush, M, Javitch, J.A, Pin, J.-P, Fan, Q.R. | 登録日 | 2012-05-05 | 公開日 | 2012-06-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | 主引用文献 | Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2. Nat.Neurosci., 15, 2012
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4FNM
| The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina | 分子名称: | DIETHYL HYDROGEN PHOSPHATE, E3 alpha-esterase-7 carboxylesterase | 著者 | Jackson, C.J, Liu, J.-W, Carr, P.D, Younis, F, Pandey, G, Coppin, C, Meirelles, T, Ollis, D.L, Tawfik, D.S, Weik, M, Oakeshott, J.G. | 登録日 | 2012-06-20 | 公開日 | 2013-12-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.804 Å) | 主引用文献 | Structure and function of an insect alpha-carboxylesterase ( alpha Esterase7) associated with insecticide resistance. Proc.Natl.Acad.Sci.USA, 110, 2013
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4HC7
| Crystal structure of the full DNA binding domain of GATA3-complex 2 | 分子名称: | DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ... | 著者 | Chen, Y, Bates, D.L, Dey, R, Chen, L. | 登録日 | 2012-09-28 | 公開日 | 2012-12-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation. Cell Rep, 2, 2012
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4F11
| Crystal structure of the extracellular domain of human GABA(B) receptor GBR2 | 分子名称: | Gamma-aminobutyric acid type B receptor subunit 2 | 著者 | Geng, Y, Xiong, D, Mosyak, L, Malito, D.L, Kniazeff, J, Chen, Y, Burmakina, S, Quick, M, Bush, M, Javitch, J.A, Pin, J.-P, Fan, Q.R. | 登録日 | 2012-05-05 | 公開日 | 2012-06-06 | 最終更新日 | 2012-08-15 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Structure and functional interaction of the extracellular domain of human GABA(B) receptor GBR2. Nat.Neurosci., 15, 2012
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2EIA
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4FNG
| The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina | 分子名称: | E3 alpha-esterase-7 caboxylesterase | 著者 | Jackson, C.J, Liu, J.-W, Carr, P.D, Younis, F, Pandey, G, Coppin, C, Meirelles, T, Ollis, D.L, Tawfik, D.S, Weik, M, Oakeshott, J.G. | 登録日 | 2012-06-19 | 公開日 | 2013-06-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure and function of an insect alpha-carboxylesterase ( alpha Esterase7) associated with insecticide resistance. Proc.Natl.Acad.Sci.USA, 110, 2013
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