2OA6
 
 | | Aristolochene synthase from Aspergillus terreus complexed with pyrophosphate | | Descriptor: | Aristolochene synthase, BETA-MERCAPTOETHANOL, GLYCEROL, ... | | Authors: | Shishova, E.Y, Di Costanzo, L, Cane, D.E, Christianson, D.W. | | Deposit date: | 2006-12-15 | | Release date: | 2007-01-30 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | X-ray crystal structure of aristolochene synthase from Aspergillus terreus and evolution of templates for the cyclization of farnesyl diphosphate
Biochemistry, 46, 2007
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3DZ7
 | | Human AdoMetDC with 5'-[(carboxamidomethyl)methylamino]-5'-deoxy-8-methyladenosine | | Descriptor: | 1,4-DIAMINOBUTANE, 2-[{[(2R,3S,4R,5R)-5-(6-amino-8-methyl-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}(methyl)amino]acetamide, S-adenosylmethionine decarboxylase alpha chain, ... | | Authors: | Bale, S, McCloskey, D.E, Pegg, A.E, Secrist III, J.A, Guida, W.C, Ealick, S.E. | | Deposit date: | 2008-07-29 | | Release date: | 2009-03-10 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | New Insights into the Design of Inhibitors of Human S-Adenosylmethionine Decarboxylase: Studies of Adenine C8 Substitution in Structural Analogues of S-Adenosylmethionine
J.Med.Chem., 52, 2009
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3DZD
 | | Crystal structure of sigma54 activator NTRC4 in the inactive state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, SODIUM ION, Transcriptional regulator (NtrC family) | | Authors: | Batchelor, J.D, Doucleff, M, Lee, C.-J, Matsubara, K, De Carlo, S, Heideker, J, Lamers, M.M, Pelton, J.G, Wemmer, D.E. | | Deposit date: | 2008-07-29 | | Release date: | 2008-11-25 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure and regulatory mechanism of Aquifex aeolicus NtrC4: variability and evolution in bacterial transcriptional regulation.
J.Mol.Biol., 384, 2008
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2O1U
 | | Structure of full length GRP94 with AMP-PNP bound | | Descriptor: | Endoplasmin, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Dollins, D.E, Warren, J.J, Immormino, R.M, Gewirth, D.T. | | Deposit date: | 2006-11-29 | | Release date: | 2007-10-23 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structures of GRP94-Nucleotide Complexes Reveal Mechanistic Differences between the hsp90 Chaperones.
Mol.Cell, 28, 2007
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2O1V
 | | Structure of full length GRP94 with ADP bound | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Endoplasmin, MAGNESIUM ION | | Authors: | Dollins, D.E, Warren, J.J, Immormino, R.M, Gewirth, D.T. | | Deposit date: | 2006-11-29 | | Release date: | 2007-10-23 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structures of GRP94-Nucleotide Complexes Reveal Mechanistic Differences between the hsp90 Chaperones.
Mol.Cell, 28, 2007
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3FBI
 | | Structure of the Mediator submodule Med7N/31 | | Descriptor: | Mediator of RNA polymerase II transcription subunit 31, Mediator of RNA polymerase II transcription subunit 7 | | Authors: | Koschubs, T, Seizl, M, Lariviere, L, Kurth, F, Baumli, S, Martin, D.E, Cramer, P. | | Deposit date: | 2008-11-19 | | Release date: | 2008-12-16 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Identification, structure, and functional requirement of the Mediator submodule Med7N/31
Embo J., 28, 2009
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2NC4
 | | Solution Structure of N-Galactosylated Pin1 WW Domain | | Descriptor: | Pin1 WW Domain, beta-D-galactopyranose | | Authors: | Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W. | | Deposit date: | 2016-03-20 | | Release date: | 2016-06-08 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
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3CGU
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2NC5
 | | Solution Structure of N-Xylosylated Pin1 WW Domain | | Descriptor: | Pin1 WW Domain, beta-D-xylopyranose | | Authors: | Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W. | | Deposit date: | 2016-03-20 | | Release date: | 2016-06-08 | | Last modified: | 2020-07-29 | | Method: | SOLUTION NMR | | Cite: | The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
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2O1W
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2NP8
 | | Structural Basis for the Inhibition of Aurora A Kinase by a Novel Class of High Affinity Disubstituted Pyrimidine Inhibitors | | Descriptor: | N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE, SULFATE ION, Serine/threonine-protein kinase 6 | | Authors: | Tari, L.W, Hoffman, I.D, Bensen, D.C, Hunter, M.J, Nix, J, Nelson, K.J, McRee, D.E, Swanson, R.V. | | Deposit date: | 2006-10-26 | | Release date: | 2006-12-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
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3DZ5
 | | Human AdoMetDC with covalently bound 5'-[(2-aminooxyethyl)methylamino]-5'-deoxy-8-methyladenosine | | Descriptor: | 1,4-DIAMINOBUTANE, 5'-{[2-(aminooxy)ethyl](methyl)amino}-5'-deoxy-8-methyladenosine, S-adenosylmethionine decarboxylase alpha chain, ... | | Authors: | Bale, S, McCloskey, D.E, Pegg, A.E, Secrist III, J.A, Guida, W.C, Ealick, S.E. | | Deposit date: | 2008-07-29 | | Release date: | 2009-03-10 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | New Insights into the Design of Inhibitors of Human S-Adenosylmethionine Decarboxylase: Studies of Adenine C8 Substitution in Structural Analogues of S-Adenosylmethionine
J.Med.Chem., 52, 2009
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3DZ3
 | | Human AdoMetDC F223A mutant with covalently bound S-Adenosylmethionine methyl ester | | Descriptor: | 1,4-DIAMINOBUTANE, S-ADENOSYLMETHIONINE METHYL ESTER, S-adenosylmethionine decarboxylase alpha chain, ... | | Authors: | Bale, S, McCloskey, D.E, Pegg, A.E, Secrist III, J.A, Guida, W.C, Ealick, S.E. | | Deposit date: | 2008-07-29 | | Release date: | 2009-03-10 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.62 Å) | | Cite: | New Insights into the Design of Inhibitors of Human S-Adenosylmethionine Decarboxylase: Studies of Adenine C8 Substitution in Structural Analogues of S-Adenosylmethionine
J.Med.Chem., 52, 2009
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2NC3
 | | Solution Structure of N-Allosylated Pin1 WW Domain | | Descriptor: | Pin1 WW Domain, beta-D-allopyranose | | Authors: | Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W. | | Deposit date: | 2016-03-20 | | Release date: | 2016-06-08 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate.
J.Am.Chem.Soc., 138, 2016
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3FBN
 | | Structure of the Mediator submodule Med7N/31 | | Descriptor: | Mediator of RNA polymerase II transcription subunit 31, Mediator of RNA polymerase II transcription subunit 7 | | Authors: | Koschubs, T, Seizl, M, Lariviere, L, Kurth, F, Baumli, S, Martin, D.E, Cramer, P. | | Deposit date: | 2008-11-19 | | Release date: | 2008-12-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.007 Å) | | Cite: | Identification, structure, and functional requirement of the Mediator submodule Med7N/31
Embo J., 28, 2009
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3DZ6
 | | Human AdoMetDC with 5'-[(4-aminooxybutyl)methylamino]-5'deoxy-8-ethyladenosine | | Descriptor: | 1,4-DIAMINOBUTANE, 5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine, S-adenosylmethionine decarboxylase alpha chain, ... | | Authors: | Bale, S, McCloskey, D.E, Pegg, A.E, Secrist III, J.A, Guida, W.C, Ealick, S.E. | | Deposit date: | 2008-07-29 | | Release date: | 2009-03-10 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | New Insights into the Design of Inhibitors of Human S-Adenosylmethionine Decarboxylase: Studies of Adenine C8 Substitution in Structural Analogues of S-Adenosylmethionine
J.Med.Chem., 52, 2009
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3FDQ
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3DGP
 | | Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2 | | Descriptor: | RNA polymerase II transcription factor B subunit 2, RNA polymerase II transcription factor B subunit 5 | | Authors: | Kainov, D.E, Cavarelli, J, Egly, J.M, Poterszman, A. | | Deposit date: | 2008-06-14 | | Release date: | 2008-08-19 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for group A trichothiodystrophy
Nat.Struct.Mol.Biol., 15, 2008
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3DOM
 | | Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2 | | Descriptor: | RNA polymerase II transcription factor B subunit 2, RNA polymerase II transcription factor B subunit 5 | | Authors: | Kainov, D.E, Cavarelli, J, Egly, J.M, Poterszman, A. | | Deposit date: | 2008-07-04 | | Release date: | 2008-08-19 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for group A trichothiodystrophy
Nat.Struct.Mol.Biol., 15, 2008
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2LL7
 | | Solution NMR structure of CaM bound to the eNOS CaM binding domain peptide | | Descriptor: | Calmodulin, Nitric oxide synthase, endothelial | | Authors: | Piazza, M, Futrega, K, Spratt, D.E, Guillemette, J.G, Dieckmann, T. | | Deposit date: | 2011-10-29 | | Release date: | 2012-05-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structure and Dynamics of Calmodulin (CaM) Bound to Nitric Oxide Synthase Peptides: Effects of a Phosphomimetic CaM Mutation.
Biochemistry, 51, 2012
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2LT8
 | | Eurocin solution structure | | Descriptor: | eurocin | | Authors: | Oeemig, J.S, Lynggaard, C, Knudsen, D.H, Hansen, F.T, Noergaard, K.D, Schneider, T, Vad, B.S, Neve, S, Kristensen, H, Sahl, H, Otzen, D.E, Wimmer, R. | | Deposit date: | 2012-05-15 | | Release date: | 2012-10-31 | | Last modified: | 2024-10-30 | | Method: | SOLUTION NMR | | Cite: | Eurocin, a New Fungal Defensin: STRUCTURE, LIPID BINDING, AND ITS MODE OF ACTION.
J.Biol.Chem., 287, 2012
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2L4K
 | | Water refined solution structure of the human Grb7-SH2 domain in complex with the 10 amino acid peptide pY1139 | | Descriptor: | Growth factor receptor-bound protein 7, Receptor tyrosine-protein kinase erbB-2 | | Authors: | Pias, S.C, Ivancic, M, Brescia, P.J, Johnson, D.L, Smith, D.E, Daly, R.J, Lyons, B.A. | | Deposit date: | 2010-10-07 | | Release date: | 2010-11-17 | | Last modified: | 2012-10-03 | | Method: | SOLUTION NMR | | Cite: | Water-Refined Solution Structure of the Human Grb7-SH2 Domain in Complex with the erbB2 Receptor Peptide pY1139.
Protein Pept.Lett., 19, 2012
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3E4B
 | | Crystal structure of AlgK from Pseudomonas fluorescens WCS374r | | Descriptor: | AlgK, CHLORIDE ION, GLYCEROL | | Authors: | Keiski, C.-L, Harwich, M, Jain, S, Neculai, A.M, Yip, P, Robinson, H, Whitney, J.C, Burrows, L.L, Ohman, D.E, Howell, P.L. | | Deposit date: | 2008-08-11 | | Release date: | 2009-08-25 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | AlgK is a TPR-containing protein and the periplasmic component of a novel exopolysaccharide secretin.
Structure, 18, 2010
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3E8Q
 | | X-ray structure of rat arginase I-T135A: the unliganded complex | | Descriptor: | Arginase-1, MANGANESE (II) ION | | Authors: | Shishova, E.Y, Di Costanzo, L, Emig, F.A, Ash, D.E, Christianson, D.W. | | Deposit date: | 2008-08-20 | | Release date: | 2008-12-02 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
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3E7L
 | | Crystal structure of sigma54 activator NtrC4's DNA binding domain | | Descriptor: | Transcriptional regulator (NtrC family), ZINC ION | | Authors: | Batchelor, J.D, Doucleff, M, Lee, C.-J, Matsubara, K, De Carlo, S, Heideker, J, Lamers, M.M, Pelton, J.G, Wemmer, D.E. | | Deposit date: | 2008-08-18 | | Release date: | 2008-11-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.252 Å) | | Cite: | Structure and regulatory mechanism of Aquifex aeolicus NtrC4: variability and evolution in bacterial transcriptional regulation.
J.Mol.Biol., 384, 2008
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