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PDB: 1151 件

5KMF
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BU of 5kmf by Molmil
Structure of CavAb in complex with nimodipine
分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ...
著者Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A.
登録日2016-06-26
公開日2016-08-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
5KJ9
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BU of 5kj9 by Molmil
Anticancer activity of Ru- and Os(arene) compounds of a maleimide-functionalized bioactive pyridinecarbothioamide ligand
分子名称: Lysozyme C, RUTHENIUM ION, SODIUM ION
著者Sullivan, M.P, Christian, C.G, Goldstone, D.C.
登録日2016-06-18
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Anticancer activity of Ru- and Os(arene) compounds of a maleimide-functionalized bioactive pyridinecarbothioamide ligand.
J. Inorg. Biochem., 165, 2016
5KTK
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BU of 5ktk by Molmil
Ketoreductase from module 3 of the bacillaene synthase from Bacillus subtilis 168
分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Polyketide synthase PksJ
著者Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T.
登録日2016-07-11
公開日2016-09-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Ketoreductase from module 3 of the bacillaene synthase from Bacillus subtilis 168
To Be Published
5KLG
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BU of 5klg by Molmil
Structure of CavAb(W195Y) in complex with Br-dihydropyridine derivative UK-59811
分子名称: 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ...
著者Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A.
登録日2016-06-24
公開日2016-08-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
6YXW
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BU of 6yxw by Molmil
Affimer K3 - KRAS protein complex
分子名称: Affimer K3, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Trinh, C.H, Haza, K.Z, Rao, A, Martin, H.L, Tiede, C, Edwards, T.A, McPherson, M.J, Tomlinson, D.C.
登録日2020-05-04
公開日2020-07-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献RAS-inhibiting biologics identify and probe druggable pockets including an SII-alpha 3 allosteric site.
Nat Commun, 12, 2021
6YR8
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BU of 6yr8 by Molmil
Affimer K6 - KRAS protein complex
分子名称: Affimer K6, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Trinh, C.H, Haza, K.Z, Rao, A, Martin, H.L, Tiede, C, Edwards, T.A, McPherson, M.J, Tomlinson, D.C.
登録日2020-04-19
公開日2020-07-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献RAS-inhibiting biologics identify and probe druggable pockets including an SII-alpha 3 allosteric site.
Nat Commun, 12, 2021
6YXE
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BU of 6yxe by Molmil
Structure of the Trim69 RING domain
分子名称: E3 ubiquitin-protein ligase TRIM69, ZINC ION
著者Keown, J.R, Goldstone, D.C.
登録日2020-05-01
公開日2020-10-14
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The RING domain of TRIM69 promotes higher-order assembly.
Acta Crystallogr D Struct Biol, 76, 2020
6N4K
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BU of 6n4k by Molmil
Dithionite-reduced nucleotide-free form of the nitrogenase Fe-protein from A. vinelandii
分子名称: IRON/SULFUR CLUSTER, Nitrogenase iron protein 1
著者Wenke, B.B, Spatzal, T, Rees, D.C.
登録日2018-11-19
公開日2019-02-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.756 Å)
主引用文献Site-Specific Oxidation State Assignments of the Iron Atoms in the [4Fe:4S]2+/1+/0States of the Nitrogenase Fe-Protein.
Angew. Chem. Int. Ed. Engl., 58, 2019
6XKA
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BU of 6xka by Molmil
TPX2 residues 7-20 fused to Aurora A residues 116-389 dephosphorylated, and CoAlated on C290
分子名称: COENZYME A, TPX2 fragment - Aurora A kinase domain fusion
著者Lim, D.C, Yaffe, M.B.
登録日2020-06-26
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Redox priming promotes Aurora A activation during mitosis.
Sci.Signal., 13, 2020
5JM7
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BU of 5jm7 by Molmil
The structure of aerobactin synthetase IucA from a hypervirulent pathotype of Klebsiella pneumoniae
分子名称: Aerobactin synthase IucA, SULFATE ION
著者Drake, E.J, Bailey, D.C, Gulick, A.M.
登録日2016-04-28
公開日2016-06-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Functional Characterization of Aerobactin Synthetase IucA from a Hypervirulent Pathotype of Klebsiella pneumoniae.
Biochemistry, 55, 2016
5JM8
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BU of 5jm8 by Molmil
The structure of ATP-bound aerobactin synthetase IucA from a hypervirulent pathotype of Klebsiella pneumoniae
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Aerobactin synthase IucA, MAGNESIUM ION
著者Bailey, D.C, Drake, E.J, Gulick, A.M.
登録日2016-04-28
公開日2016-06-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Functional Characterization of Aerobactin Synthetase IucA from a Hypervirulent Pathotype of Klebsiella pneumoniae.
Biochemistry, 55, 2016
6NZ8
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BU of 6nz8 by Molmil
Structure of carbamylated apo OXA-231 carbapenemase
分子名称: Beta-lactamase OXA-231, CHLORIDE ION, SODIUM ION
著者Favaro, D.C, Llontop, E.E, Vasconcelos, F.N, Antunes, V.U, Farah, S.C, Lincopan, N.
登録日2019-02-13
公開日2020-02-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Importance of the beta 5-beta 6 Loop for the Structure, Catalytic Efficiency, and Stability of Carbapenem-Hydrolyzing Class D beta-Lactamase Subfamily OXA-143.
Biochemistry, 58, 2019
6XGY
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BU of 6xgy by Molmil
Crystal structure of E. coli MlaFB ABC transport subunits in the dimeric state
分子名称: ABC transporter maintaining OM lipid asymmetry, cytoplasmic STAS component, ADENOSINE-5'-DIPHOSPHATE, ...
著者Chang, Y, Bhabha, G, Ekiert, D.C.
登録日2020-06-18
公開日2020-07-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation.
Elife, 9, 2020
6OY4
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BU of 6oy4 by Molmil
Crystal structure of complex between recombinant Der p 2.0103 and Fab fragment of 7A1
分子名称: Der p 2 variant 3, Fab fragment of IgG, HEAVY CHAIN, ...
著者Kapingidza, A.B, Offermann, L.R, Glesner, J, Wunschmann, S, Vailes, L.D, Chapman, M.D.C, Pomes, A, Chruszcz, M.
登録日2019-05-14
公開日2019-08-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A Human IgE Antibody Binding Site on Der p 2 for the Design of a Recombinant Allergen for Immunotherapy.
J Immunol., 203, 2019
6ONO
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BU of 6ono by Molmil
Complex structure of WhiB1 and region 4 of SigA in C2221 space group
分子名称: DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, RNA polymerase sigma factor SigA, ...
著者Wan, T, Li, S.R, Beltran, D.G, Schacht, A, Becker, D.C, Zhang, L.M.
登録日2019-04-22
公開日2019-11-27
最終更新日2020-01-22
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis of non-canonical transcriptional regulation by the sigma A-bound iron-sulfur protein WhiB1 in M. tuberculosis.
Nucleic Acids Res., 48, 2020
5J8E
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BU of 5j8e by Molmil
Crystal structure of human Hook3's conserved Hook domain
分子名称: Protein Hook homolog 3
著者Schroeder, C.M, Ekiert, D.C, Vale, R.D.
登録日2016-04-07
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Assembly and activation of dynein-dynactin by the cargo adaptor protein Hook3.
J.Cell Biol., 214, 2016
6ZB9
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BU of 6zb9 by Molmil
Exo-beta-1,3-glucanase from moose rumen microbiome, wild type
分子名称: Exo-beta-1,3-glucanase
著者Kalyani, D.C, Reichenbach, T, Aspeborg, H, Divne, C.
登録日2020-06-08
公開日2021-01-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A homodimeric bacterial exo-beta-1,3-glucanase derived from moose rumen microbiome shows a structural framework similar to yeast exo-beta-1,3-glucanases.
Enzyme.Microb.Technol., 143, 2021
6O5K
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BU of 6o5k by Molmil
Murine TRIM28 Bbox1 domain
分子名称: Transcription intermediary factor 1-beta, ZINC ION
著者Sun, Y, Keown, J.R, Goldstone, D.C.
登録日2019-03-03
公開日2019-06-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family.
J.Mol.Biol., 431, 2019
6ONU
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BU of 6onu by Molmil
Complex structure of WhiB1 and region 4 of SigA in P21 space group.
分子名称: DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, RNA polymerase sigma factor SigA, ...
著者Wan, T, Li, S.R, Beltran, D.G, Schacht, A, Becker, D.C, Zhang, L.M.
登録日2019-04-22
公開日2019-11-27
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis of non-canonical transcriptional regulation by the sigma A-bound iron-sulfur protein WhiB1 in M. tuberculosis.
Nucleic Acids Res., 48, 2020
6ZB8
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BU of 6zb8 by Molmil
Exo-beta-1,3-glucanase from moose rumen microbiome, active site mutant E167Q/E295Q
分子名称: Exo-beta-1,3-glucanase variant E167Q/E295Q, POLYETHYLENE GLYCOL (N=34)
著者Kalyani, D.C, Reichenbach, T, Aspeborg, H, Divne, C.
登録日2020-06-08
公開日2021-01-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A homodimeric bacterial exo-beta-1,3-glucanase derived from moose rumen microbiome shows a structural framework similar to yeast exo-beta-1,3-glucanases.
Enzyme.Microb.Technol., 143, 2021
6OP1
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BU of 6op1 by Molmil
Selenium incorporated, carbon monoxide inhibited FeMo-cofactor of azotobacter vinelandii
分子名称: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, CARBON MONOXIDE, ...
著者Arias, R.J, Rees, D.C.
登録日2019-04-24
公開日2019-08-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Localized Electronic Structure of Nitrogenase FeMoco Revealed by Selenium K-Edge High Resolution X-ray Absorption Spectroscopy.
J.Am.Chem.Soc., 141, 2019
1PST
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BU of 1pst by Molmil
CRYSTALLOGRAPHIC ANALYSES OF SITE-DIRECTED MUTANTS OF THE PHOTOSYNTHETIC REACTION CENTER FROM RHODOBACTER SPHAEROIDES
分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (III) ION, ...
著者Chirino, A.J, Feher, G, Rees, D.C.
登録日1993-12-13
公開日1994-04-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystallographic analyses of site-directed mutants of the photosynthetic reaction center from Rhodobacter sphaeroides.
Biochemistry, 33, 1994
1TMC
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BU of 1tmc by Molmil
THE THREE-DIMENSIONAL STRUCTURE OF A CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE MISSING THE ALPHA3 DOMAIN OF THE HEAVY CHAIN
分子名称: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-AW68), DECAMERIC PEPTIDE (EVAPPEYHRK)
著者Collins, E.J, Garboczi, D.N, Karpusas, M.N, Wiley, D.C.
登録日1994-12-19
公開日1995-03-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The three-dimensional structure of a class I major histocompatibility complex molecule missing the alpha 3 domain of the heavy chain.
Proc.Natl.Acad.Sci.USA, 92, 1995
1PSS
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BU of 1pss by Molmil
CRYSTALLOGRAPHIC ANALYSES OF SITE-DIRECTED MUTANTS OF THE PHOTOSYNTHETIC REACTION CENTER FROM RHODOBACTER SPHAEROIDES
分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (III) ION, ...
著者Chirino, A.J, Feher, G, Rees, D.C.
登録日1993-12-13
公開日1994-04-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystallographic analyses of site-directed mutants of the photosynthetic reaction center from Rhodobacter sphaeroides.
Biochemistry, 33, 1994
6BEJ
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BU of 6bej by Molmil
Crystal structure of manganese superoxide dismutase from Xanthomonas citri
分子名称: MANGANESE (II) ION, Superoxide dismutase
著者Goto, L.S, Alexandrino, A.V, Pereira, C.M, Mendoca, D.C, Leonardo, D.A, Pereira, H.M, Garratt, R.C, Novo-Mansur, M.T.M.
登録日2017-10-25
公開日2018-10-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.894 Å)
主引用文献Structural characterization of a pathogenicity-related superoxide dismutase codified by a probably essential gene in Xanthomonas citri subsp. citri.
PLoS ONE, 14, 2019

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