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PDB: 22297 件

3NY8
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Crystal structure of the human beta2 adrenergic receptor in complex with the inverse agonist ICI 118,551
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]butan-2-ol, Beta-2 adrenergic receptor, ...
著者Wacker, D, Fenalti, G, Brown, M.A, Katritch, V, Abagyan, R, Cherezov, V, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2010-07-14
公開日2010-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Conserved Binding Mode of Human beta(2) Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography
J.Am.Chem.Soc., 132, 2010
8QAU
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Outer kinetochore Ndc80-Dam1 alpha/beta-tubulin complex
分子名称: DASH complex subunit DAM1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Muir, K.W, Barford, D.
登録日2023-08-23
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Mechanism of outer kinetochore assembly on microtubules and its regulation by mitotic error correction
Biorxiv, 2023
2V3J
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The yeast ribosome synthesis factor Emg1 alpha beta knot fold methyltransferase
分子名称: ESSENTIAL FOR MITOTIC GROWTH 1, SULFATE ION
著者Leulliot, N, Bohnsack, M.T, Graille, M, Tollervey, D, Van Tilbeurgh, H.
登録日2007-06-18
公開日2007-12-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Yeast Ribosome Synthesis Factor Emg1 is a Novel Member of the Superfamily of Alpha/Beta Knot Fold Methyltransferases.
Nucleic Acids Res., 36, 2008
2V7N
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Unusual twinning in crystals of the CitS binding antibody Fab fragment f3p4
分子名称: IMMUNOGLOBULIN HEAVY CHAIN, IMMUNOGLOBULIN LIGHT CHAIN
著者Frey, D, Huber, T, Plueckthun, A, Gruetter, M.G.
登録日2007-07-31
公開日2008-06-17
最終更新日2019-05-22
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structure of the Recombinant Antibody Fab Fragment F3P4.
Acta Crystallogr.,Sect.D, 64, 2008
8PIJ
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Neisseria meningitidis Type IV pilus SB-GATDH variant bound to the C24 nanobody
分子名称: (2~{R})-~{N}-[(2~{R},3~{S},4~{S},5~{R},6~{R})-5-acetamido-2-methyl-4,6-bis(oxidanyl)oxan-3-yl]-2,3-bis(oxidanyl)propanamide, C24 nanobody, Pilin, ...
著者Fernandez-Martinez, D, Dumenil, G.
登録日2023-06-21
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms.
Nat Commun, 15, 2024
8PJP
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Neisseria meningitidis PilE, SB-GATDH variant, bound to the F10 nanobody
分子名称: (2~{R})-~{N}-[(2~{R},3~{S},4~{S},5~{R},6~{R})-5-acetamido-2-methyl-4,6-bis(oxidanyl)oxan-3-yl]-2,3-bis(oxidanyl)propanamide, Nanobody F10, Pilin, ...
著者Fernandez-Martinez, D, Dumenil, G.
登録日2023-06-23
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms.
Nat Commun, 15, 2024
1OKY
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BU of 1oky by Molmil
Structure of human PDK1 kinase domain in complex with staurosporine
分子名称: 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1, GLYCEROL, STAUROSPORINE, ...
著者Komander, D, Kular, G.S, Alessi, D.R, Van Aalten, D.M.F.
登録日2003-08-01
公開日2004-07-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for Ucn-01 (7-Hydroxystaurosporine) Specificity and Pdk1 (3-Phosphoinositide-Dependent Protein Kinase-1) Inhibition
Biochem.J., 375, 2003
1OLL
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BU of 1oll by Molmil
Extracellular region of the human receptor NKp46
分子名称: 1,2-ETHANEDIOL, NK RECEPTOR
著者Ponassi, M, Cantoni, C, Biassoni, R, Conte, R, Spallarossa, A, Pesce, A, Moretta, A, Moretta, L, Bolognesi, M, Bordo, D.
登録日2003-08-07
公開日2003-09-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure of the Human Nk Cell Triggering Receptor Nkp46 Ectodomain
Biochem.Biophys.Res.Commun., 309, 2003
2UYH
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HhaI DNA methyltransferase S87Q-Q237S mutant complex with 13mer GCGC- GMGC oligonucleotide and SAH
分子名称: 5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP *CP*C)-3', 5'-D(*TP*GP*GP*AP*TP*G*5CMP*GP*CP*TP*GP *AP*C)-3', MODIFICATION METHYLASE HHAI, ...
著者Daujotyte, D, Grazulis, S.
登録日2007-04-06
公開日2008-05-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献HhaI DNA Methyltransferase S87Q-Q237S Mutant Complex with 13mer Gcgc-Gmgc Oligonucleotide and Sah
To be Published
4CZA
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Structure of the sodium proton antiporter PaNhaP from Pyrococcus abyssii with bound thallium ion.
分子名称: ACETATE ION, NA+/H+ ANTIPORTER, PUTATIVE, ...
著者Woehlert, D, Kuhlbrandt, W, Yildiz, O.
登録日2014-04-16
公開日2014-12-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and substrate ion binding in the sodium/proton antiporter PaNhaP.
Elife, 3, 2014
3O9L
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Design and optimisation of new piperidines as renin inhibitors
分子名称: (3R,4S)-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropyl-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin
著者Corminboeuf, O, Bezencon, O, Grisostomi, C, Remen, L, Richard-Bildstein, S, Bur, D, Prade, L, Hess, P, Strickner, P, Treiber, A.
登録日2010-08-04
公開日2011-03-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Design and optimization of new piperidines as renin inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
8QCX
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Cryo-EM structure of the inward-facing FLVCR2
分子名称: Heme transporter FLVCR2
著者Weng, T.-H, Wu, D, Safarian, S.
登録日2023-08-28
公開日2024-04-17
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
2UYV
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L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI (MUTANT Q6Y- E192A)
分子名称: L(+)-TARTARIC ACID, RHAMNULOSE-1-PHOSPHATE ALDOLASE, ZINC ION
著者Grueninger, D, Schulz, G.E.
登録日2007-04-20
公開日2008-01-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Designed Protein-Protein Association.
Science, 319, 2008
1OHL
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BU of 1ohl by Molmil
YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE PUTATIVE CYCLIC REACTION INTERMEDIATE COMPLEX
分子名称: 3-[5-(AMINOMETHYL)-4-(CARBOXYMETHYL)-1H-PYRROL-3-YL]PROPANOIC ACID, BETA-MERCAPTOETHANOL, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, ...
著者Erskine, P.T, Coates, L, Butler, D, Youell, J.H, Brindley, A.A, Wood, S.P, Warren, M.J, Shoolingin-Jordan, P.M, Cooper, J.B.
登録日2003-05-27
公開日2003-06-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献X-Ray Structure of a Putative Reaction Intermediateof 5-Aminolaevulinic Acid Dehydratase
Biochem.J., 373, 2003
3NNJ
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BU of 3nnj by Molmil
Halogenase domain from CurA module (apo Hal)
分子名称: CurA
著者Khare, D, Smith, J.L.
登録日2010-06-23
公開日2010-07-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Conformational switch triggered by alpha-ketoglutarate in a halogenase of curacin A biosynthesis
Proc.Natl.Acad.Sci.USA, 107, 2010
8QCS
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Cryo-EM structure of the inward-facing FLVCR1
分子名称: Heme transporter FLVCR1
著者Weng, T.-H, Wu, D, Safarian, S.
登録日2023-08-28
公開日2024-04-17
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
8QCY
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Cryo-EM structure of the outward-facing FLVCR2
分子名称: Heme transporter FLVCR2
著者Weng, T.-H, Wu, D, Safarian, S.
登録日2023-08-28
公開日2024-04-17
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular mechanism of choline and ethanolamine transport in humans.
Nature, 630, 2024
1OKM
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CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKM INHIBITOR 4-SULFONAMIDE-[1-(4-AMINOBUTANE)]BENZAMIDE
分子名称: 4-SULFONAMIDE-[1-(4-AMINOBUTANE)]BENZAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ...
著者Elbaum, D, Nair, S.K, Patchan, M.W, Thompson, R.B, Christianson, D.W.
登録日1996-06-25
公開日1997-01-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-based design of a sulfonamide probe for fluorescence anisotropy detection of zinc with a carbonic anhydrase-based biosensor.
J.Am.Chem.Soc., 118, 1996
2VHZ
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Crystal structure of holo L-alanine dehydrogenase from Mycobacterium tuberculosis in the closed conformation
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ALANINE DEHYDROGENASE
著者Agren, D, Schneider, G.
登録日2007-11-26
公開日2008-03-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Three-Dimensional Structures of Apo- and Holo-L-Alanine Dehydrogenase from Mycobacterium Tuberculosis Reveal Conformational Changes Upon Coenzyme Binding.
J.Mol.Biol., 377, 2008
2VHW
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Crystal structure of holo L-alanine dehydrogenase from Mycobacterium tuberculosis in the open and closed conformation
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ALANINE DEHYDROGENASE, MAGNESIUM ION
著者Agren, D, Schneider, G.
登録日2007-11-26
公開日2008-03-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-Dimensional Structures of Apo- and Holo-L-Alanine Dehydrogenase from Mycobacterium Tuberculosis Reveal Conformational Changes Upon Coenzyme Binding.
J.Mol.Biol., 377, 2008
8Q7V
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Structure of the recycling U5 snRNP bound to chaperones CD2BP2 and TSSC4 (State 1)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Riabov Bassat, D, Plaschka, C, Vorlaender, M.K.
登録日2023-08-17
公開日2024-04-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of human U5 snRNP late biogenesis and recycling.
Nat.Struct.Mol.Biol., 31, 2024
1OGK
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The crystal structure of Trypanosoma cruzi dUTPase in complex with dUDP
分子名称: DEOXYURIDINE TRIPHOSPHATASE, DEOXYURIDINE-5'-DIPHOSPHATE
著者Harkiolaki, M, Dodson, E.J, Bernier-Villamor, V, Turkenburg, J.P, Gonzalez-Pacanowska, D, Wilson, K.S.
登録日2003-05-07
公開日2004-01-22
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The Crystal Structure of Trypanosoma Cruzi Dutpase Reveals a Novel Dutp/Dudp Binding Fold
Structure, 12, 2004
8Q7E
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Structure of CUL9-RBX1 ubiquitin E3 ligase complex - hexameric assembly
分子名称: Cullin-9, E3 ubiquitin-protein ligase RBX1
著者Hopf, L.V.M, Horn-Ghetko, D, Schulman, B.A.
登録日2023-08-16
公開日2024-04-17
最終更新日2024-07-31
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex.
Nat.Struct.Mol.Biol., 31, 2024
1OGL
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The crystal structure of native Trypanosoma cruzi dUTPase
分子名称: DEOXYURIDINE TRIPHOSPHATASE
著者Harkiolaki, M, Dodson, E.J, Bernier-Villamor, V, Turkenburg, J.P, Gonzalez-Pacanowska, D, Wilson, K.S.
登録日2003-05-07
公開日2004-01-22
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Crystal Structure of Trypanosoma Cruzi Dutpase Reveals a Novel Dutp/Dudp Binding Fold
Structure, 12, 2004
8Q7X
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Structure of the recycling U5 snRNP bound to chaperone CD2BP2 (State 4)
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, CD2 antigen cytoplasmic tail-binding protein 2, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Riabov Bassat, D, Plaschka, C, Vorlaender, M.K.
登録日2023-08-17
公開日2024-04-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural basis of human U5 snRNP late biogenesis and recycling.
Nat.Struct.Mol.Biol., 31, 2024

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件を2024-08-14に公開中

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