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PDB: 22600 件

1YF0
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Structural and biochemical analysis of the link between enzymatic activity and oligomerization in AhpC, a bacterial peroxiredoxin.
分子名称: Alkyl hydroperoxide reductase subunit C, SULFATE ION
著者Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B.
登録日2004-12-29
公開日2005-08-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin.
Biochemistry, 44, 2005
6W77
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30S-Inactivated-high-Mg2+ Class A
分子名称: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
著者Jahagirdar, D, Jha, V, Basu, B, Gomez-Blanco, J, Vargas, J, Ortega, J.
登録日2020-03-18
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Alternative conformations and motions adopted by 30S ribosomal subunits visualized by cryo-electron microscopy.
Rna, 26, 2020
1YJE
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Crystal structure of the rNGFI-B ligand-binding domain
分子名称: Orphan nuclear receptor NR4A1
著者Flaig, R, Greschik, H, Peluso-Iltis, C, Moras, D, Structural Proteomics in Europe (SPINE)
登録日2005-01-14
公開日2005-02-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the cell-specific activities of the NGFI-B and the Nurr1 ligand-binding domain.
J.Biol.Chem., 280, 2005
2YQH
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Crystal structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the substrate-binding form
分子名称: 2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, GLYCEROL, MAGNESIUM ION, ...
著者Miki, K, Maruyama, D, Nishitani, Y, Nonaka, T, Kita, A.
登録日2007-03-30
公開日2007-05-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Uridine-diphospho-N-acetylglucosamine Pyrophosphorylase from Candida albicans and Catalytic Reaction Mechanism
J.Biol.Chem., 282, 2007
2Y7Z
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Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs
分子名称: 6-CHLORO-N-[(3S)-1-[(1S)-1-DIMETHYLAMINO-2,3-DIHYDRO-1H-INDEN-5-YL]-2-OXO-PYRROLIDIN-3-YL]NAPHTHALENE-2-SULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ...
著者Young, R.J, Adams, C, Blows, M, Brown, D, Burns-Kurtis, C.L, Chaudry, L, Chan, C, Convery, M.A, Davies, D.E, Exall, A.M, Foster, G, Harling, J.D, Hortense, E, Irving, W.R, Irvine, S, Jackson, S, Kleanthous, S, Pateman, A.J, Patikis, A.N, Roethka, T.J, Senger, S, Stelman, G.J, Toomey, J.R, West, R.I, Whittaker, C, Zhou, P, Watson, N.S.
登録日2011-02-02
公開日2011-03-16
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Aminoindane and Phenylpyrrolidine P4 Motifs.
Bioorg.Med.Chem.Lett., 21, 2011
1YJO
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Structure of NNQQNY from yeast prion Sup35 with zinc acetate
分子名称: ACETIC ACID, Eukaryotic peptide chain release factor GTP-binding subunit, ZINC ION
著者Nelson, R, Sawaya, M.R, Balbirnie, M, Madsen, A.O, Riekel, C, Grothe, R, Eisenberg, D.
登録日2005-01-15
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure of the cross-beta spine of amyloid-like fibrils.
Nature, 435, 2005
1YJP
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Structure of GNNQQNY from yeast prion Sup35
分子名称: Eukaryotic peptide chain release factor GTP-binding subunit
著者Nelson, R, Sawaya, M.R, Balbirnie, M, Madsen, A.O, Riekel, C, Grothe, R, Eisenberg, D.
登録日2005-01-15
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the cross-beta spine of amyloid-like fibrils.
Nature, 435, 2005
6VOL
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Chloroplast ATP synthase (R2, CF1FO)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
著者Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
登録日2020-01-30
公開日2020-09-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
1YC0
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short form HGFA with first Kunitz domain from HAI-1
分子名称: Hepatocyte growth factor activator, Kunitz-type protease inhibitor 1, PHOSPHATE ION
著者Shia, S, Stamos, J, Kirchhofer, D, Fan, B, Wu, J, Corpuz, R.T, Santell, L, Lazarus, R.A, Eigenbrot, C.
登録日2004-12-21
公開日2005-02-15
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Conformational lability in serine protease active sites: structures of hepatocyte growth factor activator (HGFA) alone and with the inhibitory domain from HGFA inhibitor-1B.
J.Mol.Biol., 346, 2005
6VRM
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T cell receptor-p53-HLA-A2 complex
分子名称: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, MHC class I antigen, ...
著者Wu, D, Gallagher, D.T, Gowthaman, R, Pierce, B.G, Mariuzza, R.A.
登録日2020-02-08
公開日2020-06-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen.
Nat Commun, 11, 2020
2V7U
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X-ray crystal structure of 5'-fluorodeoxyadenosine synthase s158g mutant complexed with s-adenosylmethionine and chloride ion
分子名称: 5'-FLUORO-5'-DEOXY ADENOSINE SYNTHETASE, CHLORIDE ION, S-ADENOSYLMETHIONINE
著者Zhu, X, O'Hagan, D, Naismith, J.H.
登録日2007-08-02
公開日2008-08-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of enzymatic fluorination in Streptomyces cattleya.
J. Am. Chem. Soc., 129, 2007
1YCL
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Crystal Structure of B. subtilis LuxS in Complex with a Catalytic 2-Ketone Intermediate
分子名称: (S)-2-AMINO-4-[(2S,3R)-2,3,5-TRIHYDROXY-4-OXO-PENTYL]MERCAPTO-BUTYRIC ACID, COBALT (II) ION, S-ribosylhomocysteinase, ...
著者Rajan, R, Zhu, J, Hu, X, Pei, D, Bell, C.E.
登録日2004-12-22
公開日2005-03-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of S-Ribosylhomocysteinase (LuxS) in Complex with a Catalytic 2-Ketone Intermediate.
Biochemistry, 44, 2005
2UVM
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Structure of PKBalpha PH domain in complex with a novel inositol headgroup surrogate, benzene 1,2,3,4-tetrakisphosphate
分子名称: BENZENE-1,2,3,4-TETRAYL TETRAKIS[DIHYDROGEN (PHOSPHATE)], RAC-ALPHA SERINE/THREONINE-PROTEIN KINASE, SODIUM ION
著者Komander, D, Mills, S.J, Trusselle, M.N, Safrany, S.T, van Aalten, D.M.F, Potter, B.V.L.
登録日2007-03-12
公開日2007-04-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Novel Inositol Phospholipid Headgroup Surrogate Crystallised in the Pleckstrin Homology Domain of Protein Kinase Balpha.
Acs Chem.Biol., 2, 2007
6VOH
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Chloroplast ATP synthase (O1, CF1FO)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ...
著者Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L.
登録日2020-01-30
公開日2020-09-09
最終更新日2020-09-16
実験手法ELECTRON MICROSCOPY (4.16 Å)
主引用文献Structural basis of redox modulation on chloroplast ATP synthase.
Commun Biol, 3, 2020
6VPY
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I33M (I3.2 mutant from CH103 Lineage)
分子名称: CHLORIDE ION, GLYCEROL, I33M heavy chain, ...
著者Fera, D, Zhou, J.
登録日2020-02-04
公開日2020-07-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献The Effects of Framework Mutations at the Variable Domain Interface on Antibody Affinity Maturation in an HIV-1 Broadly Neutralizing Antibody Lineage.
Front Immunol, 11, 2020
6W1O
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RT XFEL structure of the dark-stable state of Photosystem II (0F, S1-rich) at 2.08 Angstrom resolution
分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
著者Ibrahim, M, Fransson, T, Chatterjee, R, Cheah, M.H, Hussein, R, Lassalle, L, Sutherlin, K.D, Young, I.D, Fuller, F.D, Gul, S, Kim, I.-S, Simon, P.S, de Lichtenberg, C, Chernev, P, Bogacz, I, Pham, C, Orville, A.M, Saichek, N, Northen, T.R, Batyuk, A, Carbajo, S, Alonso-Mori, R, Tono, K, Owada, S, Bhowmick, A, Bolotovski, R, Mendez, D, Moriarty, N.W, Holton, J.M, Dobbek, H, Brewster, A.S, Adams, P.D, Sauter, N.K, Bergmann, U, Zouni, A, Messinger, J, Kern, J, Yachandra, V.K, Yano, J.
登録日2020-03-04
公開日2020-05-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Untangling the sequence of events during the S2→ S3transition in photosystem II and implications for the water oxidation mechanism.
Proc.Natl.Acad.Sci.USA, 117, 2020
2V40
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Human Adenylosuccinate synthetase isozyme 2 in complex with GDP
分子名称: ADENYLOSUCCINATE SYNTHETASE ISOZYME 2, GUANOSINE-5'-DIPHOSPHATE
著者Welin, M, Moche, M, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC)
登録日2007-06-27
公開日2007-07-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Human Adenylosuccinate Synthetase Isozyme 2 in Complex with Gdp
To be Published
6VU8
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Structure of G-alpha-i bound to its chaperone Ric-8A
分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
著者Seven, A.B, Hilger, D.
登録日2020-02-14
公開日2020-03-18
最終更新日2020-03-25
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Structures of G alpha Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms.
Cell Rep, 30, 2020
6W2Q
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Junction 34, DHR53-DHR4
分子名称: CALCIUM ION, Junction 34
著者Bick, M.J, Brunette, T.J, Baker, D.
登録日2020-03-08
公開日2020-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Modular repeat protein sculpting using rigid helical junctions.
Proc.Natl.Acad.Sci.USA, 117, 2020
2VED
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crystal structure of the chimerical mutant CapABK55M protein
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, MEMBRANE PROTEIN CAPA1, ...
著者Olivares-Illana, V, Meyer, P, Gueguen-Chaignon, V, Soulat, D, Deustcher, J, Cozzone, A.J, Morera, S, Grangeasse, C, Nessler, S.
登録日2007-10-19
公開日2008-07-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Basis for the Regulation Mechanism of the Tyrosine Kinase Capb from Staphylococcus Aureus.
Plos Biol., 6, 2008
1YJ1
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X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin
分子名称: CADMIUM ION, CHLORIDE ION, Ubiquitin
著者Bang, D, Makhatadze, G.I, Tereshko, V, Kossiakoff, A.A, Kent, S.B.
登録日2005-01-13
公開日2005-06-14
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin
Angew.Chem.Int.Ed.Engl., 44, 2005
2VLQ
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F86A mutant of E9 DNase domain in complex with Im9
分子名称: COLICIN E9, COLICIN-E9 IMMUNITY PROTEIN, MALONIC ACID
著者Keeble, A.H, Joachimiak, L.A, Mate, M.J, Meenan, N, Kirkpatrick, N, Baker, D, Kleanthous, C.
登録日2008-01-15
公開日2008-05-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Experimental and Computational Analyses of the Energetic Basis for Dual Recognition of Immunity Proteins by Colicin Endonucleases.
J.Mol.Biol., 379, 2008
2UYC
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HhaI DNA methyltransferase R163N mutant complex with 13mer GCGC-GMGC oligonucleotide and SAH
分子名称: 5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP *CP*C)-3', 5'-D(*TP*GP*GP*AP*TP*GP*5CMP*GP*CP*TP *GP*AP*C)-3', GLYCEROL, ...
著者Daujotyte, D, Grazulis, S.
登録日2007-04-03
公開日2008-05-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献HhaI DNA Methyltransferase R163N Mutant Complex with 13mer Gcgc-Gmgc Oligonucleotide and Sah
To be Published
6W3D
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Rd1NTF2_05 with long sheet
分子名称: Rd1NTF2_05
著者Bick, M.J, Basanta, B, Sankaran, B, Baker, D.
登録日2020-03-09
公開日2020-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献An enumerative algorithm for de novo design of proteins with diverse pocket structures.
Proc.Natl.Acad.Sci.USA, 117, 2020
6W3G
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Rd1NTF2_04 with long sheet
分子名称: Rd1NTF2_04
著者Bick, M.J, Basanta, B, Sankaran, B, Baker, D.
登録日2020-03-09
公開日2020-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献An enumerative algorithm for de novo design of proteins with diverse pocket structures.
Proc.Natl.Acad.Sci.USA, 117, 2020

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