6P7S
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![BU of 6p7s by Molmil](/molmil-images/mine/6p7s) | Crystal Structure of the Cedar henipavirus Attachment G Glycoprotein globular domain in complex with the receptor ephrin-B1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Attachment glycoprotein, ... | Authors: | Xu, K, Nikolov, D.B, Xu, Y. | Deposit date: | 2019-06-06 | Release date: | 2019-09-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.49 Å) | Cite: | Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus. Proc.Natl.Acad.Sci.USA, 116, 2019
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7QYQ
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![BU of 7qyq by Molmil](/molmil-images/mine/7qyq) | Crystal structure of a DyP-type peroxidase from Pseudomonas putida | Descriptor: | Dyp-type peroxidase family protein, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Borges, P.T, Silva, D, Frazao, C, Martins, L.O. | Deposit date: | 2022-01-28 | Release date: | 2022-08-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.599 Å) | Cite: | Unveiling molecular details behind improved activity at neutral to alkaline pH of an engineered DyP-type peroxidase. Comput Struct Biotechnol J, 20, 2022
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6PR5
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![BU of 6pr5 by Molmil](/molmil-images/mine/6pr5) | Cryo-EM structure of HzTransib strand transfer complex (STC) | Descriptor: | DNA (30-MER), DNA (39-MER), DNA (5'-D(*GP*AP*TP*CP*TP*GP*GP*CP*CP*TP*AP*GP*AP*TP*CP*TP*CP*A)-3'), ... | Authors: | Liu, C, Yang, Y, Schatz, D.G. | Deposit date: | 2019-07-10 | Release date: | 2019-10-09 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of a RAG-like transposase during cut-and-paste transposition. Nature, 575, 2019
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6P6P
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![BU of 6p6p by Molmil](/molmil-images/mine/6p6p) | |
6MUF
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![BU of 6muf by Molmil](/molmil-images/mine/6muf) | |
6VI0
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![BU of 6vi0 by Molmil](/molmil-images/mine/6vi0) | Cryo-EM structure of VRC01.23 in complex with HIV-1 Env BG505 DS.SOSIP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 gp120, ... | Authors: | Gorman, J, Kwong, P.D. | Deposit date: | 2020-01-10 | Release date: | 2021-01-13 | Last modified: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (3.43 Å) | Cite: | A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention. Mabs, 13
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6YUP
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![BU of 6yup by Molmil](/molmil-images/mine/6yup) | Heterotetrameric structure of the rBAT-b(0,+)AT1 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neutral and basic amino acid transport protein rBAT, ... | Authors: | Wu, D, Safarian, S, Michel, H. | Deposit date: | 2020-04-27 | Release date: | 2021-01-20 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for amino acid exchange by a human heteromeric amino acid transporter. Proc.Natl.Acad.Sci.USA, 117, 2020
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6PE2
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![BU of 6pe2 by Molmil](/molmil-images/mine/6pe2) | Drosophila P element transposase strand transfer complex | Descriptor: | DNA (27-MER), DNA (5'-D(P*CP*GP*AP*AP*CP*TP*AP*TP*A)-3'), DNA (56-MER), ... | Authors: | Kellogg, E.H, Nogales, E, Ghanim, G, Rio, D.C. | Deposit date: | 2019-06-19 | Release date: | 2019-10-30 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of a P element transposase-DNA complex reveals unusual DNA structures and GTP-DNA contacts. Nat.Struct.Mol.Biol., 26, 2019
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6N2X
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![BU of 6n2x by Molmil](/molmil-images/mine/6n2x) | Anti-HIV-1 Fab 2G12 + Man9 re-refinement | Descriptor: | Fab 2G12 heavy chain, Fab 2G12 light chain, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Calarese, D.A, Stanfield, R.L, Wilson, I.A. | Deposit date: | 2018-11-14 | Release date: | 2018-11-28 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science, 300, 2003
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6Z3J
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![BU of 6z3j by Molmil](/molmil-images/mine/6z3j) | Repulsive Guidance Molecule B (RGMB) in complex with Growth Differentiation Factor 5 (GDF5) (crystal form 1) | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Malinauskas, T, Peer, T.V, Bishop, B, Muller, T.D, Siebold, C. | Deposit date: | 2020-05-20 | Release date: | 2020-07-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Repulsive guidance molecules lock growth differentiation factor 5 in an inhibitory complex. Proc.Natl.Acad.Sci.USA, 117, 2020
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7TLY
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6PCI
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![BU of 6pci by Molmil](/molmil-images/mine/6pci) | EBOV GPdMuc (Makona) in complex with rEBOV-520 and rEBOV-548 Fabs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Virion spike glycoprotein, Virion spike glycoprotein,Virion spike glycoprotein,Ebola Virus (Makona) GP2, ... | Authors: | Ward, A.B, Murin, C.D, Alkutkar, T. | Deposit date: | 2019-06-17 | Release date: | 2020-03-11 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.12 Å) | Cite: | Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization. Immunity, 52, 2020
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7QH1
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![BU of 7qh1 by Molmil](/molmil-images/mine/7qh1) | Discovery and development of a novel inhaled antivirulence therapy for the treatment of Pseudomonas aeruginosa infections in patients with chronic respiratory disease | Descriptor: | 2-[2-[[5-[3-[bis(2-hydroxyethyl)-methyl-$l^{4}-azanyl]propoxy]-6-methoxy-1,3-benzothiazol-2-yl]methylcarbamoyl]-5,6-bis(fluoranyl)-1,3-dihydroinden-2-yl]ethanoic acid, CALCIUM ION, Keratinase KP2, ... | Authors: | Leonard, P.M, Davies, D, Pallin, T.D. | Deposit date: | 2021-12-10 | Release date: | 2022-12-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1 beta in Cellular and Animal Infection Models. Acs Infect Dis., 9, 2023
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6MTN
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![BU of 6mtn by Molmil](/molmil-images/mine/6mtn) | |
6MU8
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![BU of 6mu8 by Molmil](/molmil-images/mine/6mu8) | |
7P36
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![BU of 7p36 by Molmil](/molmil-images/mine/7p36) | X-ray structure of Lactobacillus kefir alcohol dehydrogenase (wild type) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Bischoff, D, Walla, B, Janowski, R, Niessing, D, Weuster-Botz, D. | Deposit date: | 2021-07-07 | Release date: | 2021-07-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Transfer of a Rational Crystal Contact Engineering Strategy between Diverse Alcohol Dehydrogenases Crystals, 11, 2021
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6Z2M
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![BU of 6z2m by Molmil](/molmil-images/mine/6z2m) | H11-D4, SARS-CoV-2 RBD, CR3022 ternary complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 antibody, Spike glycoprotein, ... | Authors: | Naismith, J.H, Ren, J, Zhou, D, Zhao, Y, Stuart, D.I. | Deposit date: | 2020-05-17 | Release date: | 2020-06-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structural characterisation of a nanobody derived from a naive library that neutralises SARS-CoV-2 To Be Published
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6N1W
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7P7Y
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![BU of 7p7y by Molmil](/molmil-images/mine/7p7y) | X-ray structure of Lactobacillus kefir alcohol dehydrogenase mutant Q126K | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Bischoff, D, Walla, B, Janowski, R, Niessing, D, Weuster-Botz, D. | Deposit date: | 2021-07-21 | Release date: | 2021-07-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Transfer of a Rational Crystal Contact Engineering Strategy between Diverse Alcohol Dehydrogenases Crystals, 11, 2021
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7QKC
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![BU of 7qkc by Molmil](/molmil-images/mine/7qkc) | Crystal structure of human Cathepsin L after incubation with Sulfo-Calpeptin | Descriptor: | Calpeptin, Cathepsin L, DI(HYDROXYETHYL)ETHER | Authors: | Reinke, P.Y.A, Falke, S, Lieske, J, Ewert, W, Loboda, J, Rahmani Mashhour, A, Hauser, M, Karnicar, K, Usenik, A, Lindic, N, Lach, M, Boehler, H, Beck, T, Cox, R, Chapman, H.N, Hinrichs, W, Turk, D, Guenther, S, Meents, A. | Deposit date: | 2021-12-17 | Release date: | 2022-12-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections. Commun Biol, 6, 2023
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7TY0
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![BU of 7ty0 by Molmil](/molmil-images/mine/7ty0) | |
7TPS
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![BU of 7tps by Molmil](/molmil-images/mine/7tps) | Crystal structure of ALPN-202 (engineered CD80 vIgD) in complex with PD-L1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Demonte, D.W, Maurer, M.F, Akutsu, M, Kimbung, Y.R, Logan, D.T, Walse, B. | Deposit date: | 2022-01-26 | Release date: | 2022-03-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity. Nat Commun, 13, 2022
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7BEP
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![BU of 7bep by Molmil](/molmil-images/mine/7bep) | Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in a ternary complex with COVOX-384 and S309 Fabs | Descriptor: | CHLORIDE ION, COVOX-384 heavy chain, COVOX-384 light chain, ... | Authors: | Zhou, D, Zhao, Y, Ren, J, Stuart, D. | Deposit date: | 2020-12-24 | Release date: | 2021-03-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | The antigenic anatomy of SARS-CoV-2 receptor binding domain. Cell, 184, 2021
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7BEL
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![BU of 7bel by Molmil](/molmil-images/mine/7bel) | Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in a ternary complex with COVOX-88 and COVOX-45 Fabs | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, COVOX-45 heavy chain, ... | Authors: | Zhou, D, Zhao, Y, Ren, J, Stuart, D. | Deposit date: | 2020-12-23 | Release date: | 2021-03-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | The antigenic anatomy of SARS-CoV-2 receptor binding domain. Cell, 184, 2021
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6MU6
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![BU of 6mu6 by Molmil](/molmil-images/mine/6mu6) | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-814508 in Complex with Human Antibodies 3H109L and 35O22 at 3.2 Angstrom | Descriptor: | (2R)-{1-[{7-[2-({[3-(dimethylamino)propyl](methyl)amino}methyl)-1,3-thiazol-4-yl]-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl}(oxo)acetyl]piperidin-4-yl}(phenyl)acetonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lai, Y.-T, Kwong, P.D. | Deposit date: | 2018-10-22 | Release date: | 2019-01-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.551 Å) | Cite: | Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry. Nat Commun, 10, 2019
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