3EKJ
 
 | | Calcium-free GCaMP2 (calcium binding deficient mutant) | | Descriptor: | Myosin light chain kinase, Green fluorescent protein, Calmodulin chimera | | Authors: | Akerboom, J, Velez Rivera, J.D, Looger, L.L, Schreiter, E.R. | | Deposit date: | 2008-09-19 | | Release date: | 2008-12-16 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design
J.Biol.Chem., 284, 2009
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8D05
 | | Hallucinated C2 protein assembly HALC2_065 | | Descriptor: | HALC2_065 | | Authors: | Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D. | | Deposit date: | 2022-05-25 | | Release date: | 2022-09-28 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Hallucinating symmetric protein assemblies.
Science, 378, 2022
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8K8H
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6VPL
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2MA9
 | | HIV-1 Vif SOCS-box and Elongin BC solution structure | | Descriptor: | Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, Virion infectivity factor | | Authors: | Lu, Z, Bergeron, J.R, Atkinson, R.A, Schaller, T, Veselkov, D.A, Oregioni, A, Yang, Y, Matthews, S.J, Malim, M.H, Sanderson, M.R. | | Deposit date: | 2013-07-01 | | Release date: | 2013-12-11 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Insight into the HIV-1 Vif SOCS-box-ElonginBC interaction.
OPEN BIOLOGY, 3, 2013
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2LYQ
 | | NOE-based 3D structure of the monomeric intermediate of CylR2 at 262K (-11 Celsius degrees) | | Descriptor: | CylR2 | | Authors: | Jaremko, M, Jaremko, L, Kim, H, Cho, M, Schwieters, C.D, Giller, K, Becker, S, Zweckstetter, M. | | Deposit date: | 2012-09-19 | | Release date: | 2013-02-20 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Cold denaturation of a protein dimer monitored at atomic resolution.
Nat.Chem.Biol., 9, 2013
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2M57
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6VWN
 | | 70S ribosome bound to HIV frameshifting stem-loop (FSS) and P-site tRNA (non-rotated conformation, Structure II) | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Loerch, S, Bao, C, Ling, C, Korostelev, A.A, Grigorieff, N, Ermolenko, D.M. | | Deposit date: | 2020-02-20 | | Release date: | 2020-06-03 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding.
Elife, 9, 2020
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8D03
 | | Hallucinated C2 protein assembly HALC2_068 | | Descriptor: | HALC2_068 | | Authors: | Ragotte, R.J, Bera, A.K, Wicky, B.I.M, Milles, L.F, Baker, D. | | Deposit date: | 2022-05-25 | | Release date: | 2022-09-28 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Hallucinating symmetric protein assemblies.
Science, 378, 2022
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8CT2
 | | Local refinement of AQP1 tetramer (C1; refinement mask included D1 of protein 4.2 and Ankyrin-1 AR1-5) in Class 2 of erythrocyte ankyrin-1 complex | | Descriptor: | Aquaporin-1, CHOLESTEROL | | Authors: | Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. | | Deposit date: | 2022-05-13 | | Release date: | 2022-07-20 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
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1AJ4
 | | STRUCTURE OF CALCIUM-SATURATED CARDIAC TROPONIN C, NMR, 1 STRUCTURE | | Descriptor: | CALCIUM ION, TROPONIN C | | Authors: | Sia, S.K, Li, M.X, Spyracopoulos, L, Gagne, S.M, Liu, W, Putkey, J.A, Sykes, B.D. | | Deposit date: | 1997-05-14 | | Release date: | 1998-05-20 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of cardiac muscle troponin C unexpectedly reveals a closed regulatory domain.
J.Biol.Chem., 272, 1997
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2MBQ
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5IJE
 | | Crystal structure of Equine Serum Albumin in the presence of 30 mM zinc at pH 7.4 | | Descriptor: | SULFATE ION, Serum albumin, ZINC ION | | Authors: | Handing, K.B, Shabalin, I.G, Cooper, D.R, Szlachta, K, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | | Deposit date: | 2016-03-01 | | Release date: | 2016-04-27 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins.
Chem Sci, 7, 2016
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8QBT
 | | E. coli ApdP-stalled ribosomal complex | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ... | | Authors: | Morici, M, Wilson, D.N. | | Deposit date: | 2023-08-25 | | Release date: | 2024-03-20 | | Last modified: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (2.2 Å) | | Cite: | RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity.
Nat Commun, 15, 2024
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8QCQ
 | | B. subtilis ApdA-stalled ribosomal complex | | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | Authors: | Morici, M, Wilson, D.N. | | Deposit date: | 2023-08-28 | | Release date: | 2024-03-20 | | Last modified: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity.
Nat Commun, 15, 2024
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2M2Y
 | | Solution structure of the antimicrobial peptide Btd-2[3,4] | | Descriptor: | BTD-2[3,4] | | Authors: | Conibear, A.C, Rosengren, K, Daly, N.L, Troiera Henriques, S, Craik, D.J. | | Deposit date: | 2013-01-03 | | Release date: | 2013-02-27 | | Last modified: | 2024-10-09 | | Method: | SOLUTION NMR | | Cite: | The cyclic cystine ladder in theta-defensins is important for structure and stability, but not antibacterial activity.
J.Biol.Chem., 288, 2013
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7AWE
 | | HUMAN IMMUNOPROTEASOME 20S PARTICLE IN COMPLEX WITH [(1R)-2-(1-benzofuran-3-yl)-1-{[(1S,2R,4R)-7-oxabicyclo[2.2.1]heptan-2-yl]formamido}ethyl]boronic acid | | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | Authors: | Musil, D, Klein, M. | | Deposit date: | 2020-11-06 | | Release date: | 2021-06-09 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.288 Å) | | Cite: | M3258 Is a Selective Inhibitor of the Immunoproteasome Subunit LMP7 ( beta 5i) Delivering Efficacy in Multiple Myeloma Models.
Mol.Cancer Ther., 20, 2021
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6W9O
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2MGP
 | | Structure of Plasmodium Yoelii Merozoite Surface Protein 1 - C-terminal Domain | | Descriptor: | Merozoite surface protein 1 | | Authors: | Curd, R.D, Birdsall, B, Kadekoppala, M, Ogun, S, Kelly, G, Holder, A.A. | | Deposit date: | 2013-11-03 | | Release date: | 2014-02-12 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | The structure of Plasmodium yoelii merozoite surface protein 119, antibody specificity and implications for malaria vaccine design
OPEN BIOLOGY, 4, 2014
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2MMZ
 | | Solution structure of the apo form of human glutaredoxin 5 | | Descriptor: | Glutaredoxin-related protein 5, mitochondrial | | Authors: | Banci, L, Brancaccio, D, Ciofi-Baffoni, S, Del Conte, R, Gadepalli, R, Mikolajczyk, M, Neri, S, Piccioli, M, Winkelmann, J. | | Deposit date: | 2014-03-25 | | Release date: | 2014-04-16 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | [2Fe-2S] cluster transfer in iron-sulfur protein biogenesis.
Proc.Natl.Acad.Sci.USA, 111, 2014
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2M37
 | | Structure of lasso peptide astexin-1 | | Descriptor: | ASTEXIN-1 | | Authors: | Zimmermann, M, Hegemann, J.D, Xie, X, Marahiel, M.A. | | Deposit date: | 2013-01-14 | | Release date: | 2013-05-01 | | Last modified: | 2024-11-06 | | Method: | SOLUTION NMR | | Cite: | The astexin-1 lasso peptides: biosynthesis, stability, and structural studies.
Chem.Biol., 20, 2013
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8D6T
 | | Rana catesbeiana saxiphilin mutant - Y558I:STX (co-crystal) | | Descriptor: | CACODYLATE ION, Saxiphilin, [(3aS,4R,10aS)-2,6-diamino-10,10-dihydroxy-3a,4,9,10-tetrahydro-3H,8H-pyrrolo[1,2-c]purin-4-yl]methyl carbamate | | Authors: | Chen, Z, Zakrzewska, S, Minor, D.L. | | Deposit date: | 2022-06-06 | | Release date: | 2022-11-02 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Definition of a saxitoxin (STX) binding code enables discovery and characterization of the anuran saxiphilin family.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8D3Q
 | | Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/NoPAM prespacer | | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endonuclease Cas2, CRISPR-associated exonuclease Cas4, ... | | Authors: | Dhingra, Y, Suresh, S.K, Juneja, P, Sashital, D.G. | | Deposit date: | 2022-06-01 | | Release date: | 2022-11-02 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation.
Mol.Cell, 82, 2022
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2M6L
 | | Solution structure of the Escherichia coli holo ferric enterobactin binding protein | | Descriptor: | Ferrienterobactin-binding periplasmic protein | | Authors: | Chu, B.C.H, Otten, R, Krewulak, K.D, Mulder, F.A.A, Vogel, H.J. | | Deposit date: | 2013-04-05 | | Release date: | 2014-04-30 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The solution structure, binding properties, and dynamics of the bacterial siderophore-binding protein FepB.
J.Biol.Chem., 289, 2014
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8DPR
 | | Crystal structure of SARS-CoV-2 main protease in complex with inhibitor TKB-248 | | Descriptor: | 2,2,2-trifluoro-N-{(2S)-1-[(1R,2S,5S)-2-({(2S)-1-(4-fluoro-1,3-benzothiazol-2-yl)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}carbamothioyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexan-3-yl]-3,3-dimethyl-1-oxobutan-2-yl}acetamide, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, ... | | Authors: | Bulut, H, Hayashi, H, Tsuji, K, Kuwata, N, Das, D, Tamamura, H, Mitsuya, H. | | Deposit date: | 2022-07-16 | | Release date: | 2022-08-24 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Identification of SARS-CoV-2 M pro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2.
Nat Commun, 14, 2023
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