6TX7
| |
6DJD
| Crystal structure of Tdp1 catalytic domain in complex with Zenobia fragment ZT1982 (single soak) | 分子名称: | 1,2-ETHANEDIOL, 4-hydroxyquinoline-3-carboxylic acid, Tyrosyl-DNA phosphodiesterase 1 | 著者 | Lountos, G.T, Zhao, X.Z, Kiselev, E, Tropea, J.E, Needle, D, Burke Jr, T.R, Pommier, Y, Waugh, D.S. | 登録日 | 2018-05-25 | 公開日 | 2019-05-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.777 Å) | 主引用文献 | Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening. Nucleic Acids Res., 2019
|
|
2QHR
| Crystal structure of the 13F6-1-2 Fab fragment bound to its Ebola virus glycoprotein peptide epitope. | 分子名称: | 13F6-1-2 Fab fragment V lambda x light chain, 13F6-1-2 Fab fragment heavy chain, Envelope glycoprotein peptide | 著者 | Lee, J.E, Kuehne, A, Abelson, D.M, Fusco, M.L, Hart, M.K, Saphire, E.O. | 登録日 | 2007-07-02 | 公開日 | 2008-01-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Complex of a protective antibody with its Ebola virus GP peptide epitope: unusual features of a V lambda x light chain. J.Mol.Biol., 375, 2008
|
|
4DNU
| Crystal structure of the W285A mutant of UVB-resistance protein UVR8 | 分子名称: | AT5g63860/MGI19_6 | 著者 | Wu, D, Hu, Q, Yan, Z, Chen, W, Yan, C, Zhang, J, Wang, J, Shi, Y. | 登録日 | 2012-02-09 | 公開日 | 2012-03-07 | 最終更新日 | 2013-07-17 | 実験手法 | X-RAY DIFFRACTION (1.764 Å) | 主引用文献 | Structural basis of ultraviolet-B perception by UVR8. Nature, 484, 2012
|
|
4DUC
| cytochrome P450 BM3h-2G9 MRI sensor, no ligand | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 BM3 variant 2G9 | 著者 | Brustad, E.M, Lelyveld, V.S, Snow, C.D, Crook, N, Martinez, F.M, Scholl, T.J, Jasanoff, A, Arnold, F.H. | 登録日 | 2012-02-21 | 公開日 | 2012-06-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin. J.Mol.Biol., 422, 2012
|
|
6DJN
| Cryo-EM structure of ADP-Pi-actin filaments | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Chou, S.Z, Pollard, T.D. | 登録日 | 2018-05-25 | 公開日 | 2019-02-27 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
5E8P
| The structure of the TEIPP associated altered peptide ligand Trh4-p5NLE in complex with H-2D(b) | 分子名称: | Beta-2-microglobulin, Ceramide synthase 5, H-2 class I histocompatibility antigen, ... | 著者 | Hafstrand, I, Doorduijn, E, Duru, A.D, Buratto, J, Oliveira, C.C, Sandalova, T, van Hall, T, Achour, A. | 登録日 | 2015-10-14 | 公開日 | 2016-02-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The MHC Class I Cancer-Associated Neoepitope Trh4 Linked with Impaired Peptide Processing Induces a Unique Noncanonical TCR Conformer. J Immunol., 196, 2016
|
|
1VJM
| Deformation of helix C in the low-temperature L-intermediate of bacteriorhodopsin | 分子名称: | Bacteriorhodopsin, RETINAL | 著者 | Edman, K, Royant, A, Larsson, G, Jacobson, F, Taylor, T, van der Spoel, D, Landau, E.M, Pebay-Peyroula, E, Neutze, R. | 登録日 | 2004-03-12 | 公開日 | 2004-04-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Deformation of helix C in the low temperature L-intermediate of bacteriorhodopsin. J.Biol.Chem., 279, 2004
|
|
2QOG
| Crotoxin B, the basic PLA2 from Crotalus durissus terrificus. | 分子名称: | CALCIUM ION, Phospholipase A2 CB1, Phospholipase A2 CB2 | 著者 | Marchi-Salvador, D.P, Correa, L.C, Fontes, M.R.M. | 登録日 | 2007-07-20 | 公開日 | 2008-04-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Insights into the role of oligomeric state on the biological activities of crotoxin: crystal structure of a tetrameric phospholipase A2 formed by two isoforms of crotoxin B from Crotalus durissus terrificus venom. Proteins, 72, 2008
|
|
4DYT
| Crystal Structure of WSN/A Influenza Nucleoprotein with Three Mutations (E53D, Y289H, Y313V) | 分子名称: | Nucleocapsid protein | 著者 | Lewis, H.A, Baldwin, E.T, Steinbacher, S, Maskos, K, Mortl, M, Kiefersauer, R, Edavettal, S, McDonnell, P.A, Pearce, B.C, Langley, D.R. | 登録日 | 2012-02-29 | 公開日 | 2013-03-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | To be determined To be Published
|
|
5LP3
| |
7XNK
| human KCNQ1-CaM in complex with ML277 | 分子名称: | (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide, Calmodulin-3, POTASSIUM ION, ... | 著者 | Ma, D, Guo, J. | 登録日 | 2022-04-29 | 公開日 | 2022-12-14 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
6UDW
| S2 symmetric peptide design number 3 crystal form 2, Lurch | 分子名称: | S2-3, Lurch crystal form 2 | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-19 | 公開日 | 2020-09-23 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
|
|
7X1R
| Cryo-EM structure of human thioredoxin reductase bound by Au | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GOLD ION, Thioredoxin reductase 1, ... | 著者 | He, Z.S, Cao, P, Cao, S.H, He, B, Jiang, H.D, Gong, Y, Gao, X.Y. | 登録日 | 2022-02-24 | 公開日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Au4 cluster inhibits human thioredoxin reductase activity via specifically binding of Au to Cys189 Nano Today, 47, 2022
|
|
1M34
| Nitrogenase Complex From Azotobacter Vinelandii Stabilized By ADP-Tetrafluoroaluminate | 分子名称: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | 著者 | Schmid, B, Einsle, O, Chiu, H.-J, Willing, A, Yoshida, M, Howard, J.B, Rees, D.C. | 登録日 | 2002-06-27 | 公開日 | 2003-02-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Biochemical and Structural Characterization of the Crosslinked Complex of Nitrogenase: Comparison to the ADP-AlF4 Stabilized structure Biochemistry, 41, 2002
|
|
4DUD
| cytochrome P450 BM3h-2G9C6 MRI sensor, no ligand | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 BM3 variant 2G9C6 | 著者 | Brustad, E.M, Lelyveld, V.S, Snow, C.D, Crook, N, Martinez, F.M, Scholl, T.J, Jasanoff, A, Arnold, F.H. | 登録日 | 2012-02-21 | 公開日 | 2012-06-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin. J.Mol.Biol., 422, 2012
|
|
7XNI
| human KCNQ1-CaM in apo state | 分子名称: | Calmodulin-3, Potassium voltage-gated channel subfamily KQT member 1 | 著者 | Ma, D, Guo, J. | 登録日 | 2022-04-28 | 公開日 | 2022-12-14 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
6D6G
| Triclinic lysozyme (295 K) in the presence of 47% MPD | 分子名称: | Lysozyme C, NITRATE ION | 著者 | Juers, D.H. | 登録日 | 2018-04-20 | 公開日 | 2018-09-19 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order. Acta Crystallogr D Struct Biol, 74, 2018
|
|
1MNQ
| Thioesterase Domain of Picromycin Polyketide Synthase (PICS TE), pH 8.4 | 分子名称: | polyketide synthase IV | 著者 | Tsai, S.-C, Lu, H, Cane, D.E, Khosla, C, Stroud, R.M. | 登録日 | 2002-09-05 | 公開日 | 2003-02-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Insights into channel architecture and substrate specificity from crystal structures of two macrocycle-forming thioesterases of modular polyketide synthases Biochemistry, 41, 2002
|
|
4MEM
| Crystal Structure of the rat USP11 DUSP-UBL domains | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 11 | 著者 | Harper, S, Gratton, H.E, Cornaciu, I, Oberer, M, Scott, D.J, Emsley, J, Dreveny, I. | 登録日 | 2013-08-27 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Structure and Catalytic Regulatory Function of Ubiquitin Specific Protease 11 N-Terminal and Ubiquitin-like Domains. Biochemistry, 53, 2014
|
|
4DDY
| |
4DE9
| LytR-CPS2A-psr family protein YwtF (TagT) with bound octaprenyl pyrophosphate lipid | 分子名称: | (2Z,6Z,10Z,14Z,18Z,22E,26E)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl trihydrogen diphosphate, Putative transcriptional regulator ywtF | 著者 | Eberhardt, A, Hoyland, C.N, Vollmer, D, Bisle, S, Cleverley, R.M, Johnsborg, O, Havarstein, S, Lewis, R.J, Vollmer, W. | 登録日 | 2012-01-20 | 公開日 | 2012-04-04 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.787 Å) | 主引用文献 | Attachment of Capsular Polysaccharide to the Cell Wall in Streptococcus pneumoniae. Microb Drug Resist, 18, 2012
|
|
2R0B
| Crystal structure of human tyrosine phosphatase-like serine/threonine/tyrosine-interacting protein | 分子名称: | GLYCEROL, SULFATE ION, Serine/threonine/tyrosine-interacting protein | 著者 | Bonanno, J.B, Freeman, J, Bain, K.T, Iizuka, M, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2007-08-18 | 公開日 | 2007-08-28 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
|
|
3T3J
| |
6TXZ
| FAB PART OF M6903 IN COMPLEX WITH HUMAN TIM3 | 分子名称: | Fab H, Fab L, Hepatitis A virus cellular receptor 2 | 著者 | Musil, D, Sood, V. | 登録日 | 2020-01-15 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.06 Å) | 主引用文献 | Identification and characterization of M6903, an antagonistic anti-TIM-3 monoclonal antibody. Oncoimmunology, 9, 2020
|
|