6HJQ
| |
6SG9
| Head domain of the mt-SSU assemblosome from Trypanosoma brucei | 分子名称: | 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N. | 登録日 | 2019-08-03 | 公開日 | 2019-09-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery. Science, 365, 2019
|
|
6YI0
| Human histidine triad nucleotide-binding protein 2 (hHINT2) refined to 1.65 A in P41212 space group | 分子名称: | Histidine triad nucleotide-binding protein 2, mitochondrial, SODIUM ION | 著者 | Dolot, R.D, Wlodarczyk, A, Bujacz, G.D, Nawrot, B.C. | 登録日 | 2020-03-31 | 公開日 | 2020-04-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Biochemical, crystallographic and biophysical characterization of histidine triad nucleotide-binding protein 2 with different ligands including a non-hydrolyzable analog of Ap4A. Biochim Biophys Acta Gen Subj, 1865, 2021
|
|
5MBK
| Structure of a bacterial light-regulated adenylyl cylcase | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Beta subunit of photoactivated adenylyl cyclase, MAGNESIUM ION | 著者 | Lindner, R, Hartmann, E, Tarnawski, M, Winkler, A, Frey, D, Reinstein, J, Meinhart, A, Schlichting, I. | 登録日 | 2016-11-08 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase. J. Mol. Biol., 429, 2017
|
|
5KCW
| Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with an N-trifluoroethyl OBHS-N derivative | 分子名称: | (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-N-phenyl-N-(2,2,2-trifluoroethyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonamide, Estrogen receptor, NCOA2 | 著者 | Nwachukwu, J.C, Srinivasan, S, Bruno, N.E, Dharmarajan, V, Goswami, D, Kastrati, I, Novick, S, Nowak, J, Zhou, H.B, Boonmuen, N, Zhao, Y, Min, J, Frasor, J, Katzenellenbogen, B.S, Griffin, P.R, Katzenellenbogen, J.A, Nettles, K.W. | 登録日 | 2016-06-07 | 公開日 | 2016-11-16 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.905 Å) | 主引用文献 | Full antagonism of the estrogen receptor without a prototypical ligand side chain. Nat. Chem. Biol., 13, 2017
|
|
8TQ0
| |
8CQZ
| Homo sapiens Get3 in complex with the Get1 cytoplasmic domain | 分子名称: | ATPase ASNA1, Guided entry of tail-anchored proteins factor 1 | 著者 | McDowell, M.A, Heimes, M, Wild, K, Saar, D, Sinning, I. | 登録日 | 2023-03-07 | 公開日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The GET insertase exhibits conformational plasticity and induces membrane thinning. Nat Commun, 14, 2023
|
|
8TWU
| Crystal structure of Cytochrome P450 AspB bound to N1-methylated cyclo-L-Trp-L-Pro | 分子名称: | (3S,5S,8aS)-3-[(1-methyl-1H-indol-3-yl)methyl]hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, Cytochrome P450 AspB, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Gering, H.E, Li, X, Tang, H, Swartz, P.D, Chang, W.-C, Makris, T.M. | 登録日 | 2023-08-21 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | A Ferric-Superoxide Intermediate Initiates P450-Catalyzed Cyclic Dipeptide Dimerization. J.Am.Chem.Soc., 145, 2023
|
|
7AMH
| SmBRD3(2), Second Bromodomain of Bromodomain 3 from Schistosoma mansoni in complex with DM-A-33, an iBET726 analogue | 分子名称: | 4-{(2S, 4R)-1-acetyl-4-[(1-benzothiophen-6-yl)amino]-2-methyl-1,2,3,4-tetrahydroquinolin-6-yl}benzoic acid, Putative bromodomain-containing protein 3, ... | 著者 | McArdle, D, Schiedel, M, McDonough, M.A, Conway, S.J. | 登録日 | 2020-10-08 | 公開日 | 2021-10-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.863 Å) | 主引用文献 | SBM3_2, Second Bromodomain of Bromodomain 3 from Schistosoma mansoni in complex with DM1, an iBET726 analogue To Be Published
|
|
8CP6
| |
5CDQ
| 2.95A structure of Moxifloxacin with S.aureus DNA gyrase and DNA | 分子名称: | 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA (5'-D(P*GP*AP*GP*CP*GP*TP*AP*T*GP*GP*CP*CP*AP*TP*AP*CP*GP*CP*TP*T)-3'), DNA gyrase subunit A, ... | 著者 | Bax, B.D, Srikannathasan, V, Chan, P.F. | 登録日 | 2015-07-04 | 公開日 | 2015-12-16 | 最終更新日 | 2016-12-21 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin. Nat Commun, 6, 2015
|
|
7KU0
| Data clustering and dynamics of chymotrypsinogen cluster 138 (yellow) structure | 分子名称: | Chymotrypsinogen A, SULFATE ION | 著者 | Nguyen, T, Phan, K.L, Kreitler, D.F, Andrews, L.C, Gabelli, S.B, Kozakov, D, Jakoncic, J, Sweet, R.M, Soares, A.S, Bernstein, H.J. | 登録日 | 2020-11-24 | 公開日 | 2021-03-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs. Acta Crystallogr D Struct Biol, 78, 2022
|
|
6SC7
| dAb3/HOIP-RBR-Ligand3 | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase RNF31, SULFATE ION, ... | 著者 | Tsai, Y.-C.I, Johansson, H, House, D, Rittinger, K. | 登録日 | 2019-07-23 | 公開日 | 2019-11-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases. Cell Chem Biol, 27, 2020
|
|
6HS4
| Crystal structure of Ebolavirus glycoprotein in complex with inhibitor 118 | 分子名称: | 1-[2-[3-oxidanyl-4-(4-phenyl-1~{H}-pyrazol-5-yl)phenoxy]ethyl]piperidine-4-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Ren, J, Zhao, Y, Stuart, D.I. | 登録日 | 2018-09-28 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structure-Based in Silico Screening Identifies a Potent Ebolavirus Inhibitor from a Traditional Chinese Medicine Library. J.Med.Chem., 62, 2019
|
|
7STE
| Rad24-RFC ADP state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Checkpoint protein RAD24, ... | 著者 | Castaneda, J.C, Schrecker, M, Remus, D, Hite, R.K. | 登録日 | 2021-11-12 | 公開日 | 2022-04-06 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Mechanisms of loading and release of the 9-1-1 checkpoint clamp. Nat.Struct.Mol.Biol., 29, 2022
|
|
6YQT
| CRYSTAL STRUCTURE OF HUMAN CA II IN COMPLEX WITH A SULFONAMIDE DERIVATIVE OF 2-MERCAPTOBENZOXAZOLE | 分子名称: | 2-sulfanylidene-3~{H}-1,3-benzoxazole-5-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | 著者 | Alterio, V, De Simone, G, Esposito, D. | 登録日 | 2020-04-18 | 公開日 | 2020-07-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | 2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site. Chem.Commun.(Camb.), 56, 2020
|
|
6SHT
| Molecular structure of mouse apoferritin resolved at 2.7 Angstroms with the Glacios cryo-microscope | 分子名称: | FE (III) ION, Ferritin heavy chain, MAGNESIUM ION | 著者 | Hamdi, F, Tueting, C, Semchonok, D, Kyrilis, F, Meister, A, Skalidis, I, Schmidt, L, Parthier, C, Stubbs, M.T, Kastritis, P.L. | 登録日 | 2019-08-08 | 公開日 | 2020-05-13 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | 2.7 angstrom cryo-EM structure of vitrified M. musculus H-chain apoferritin from a compact 200 keV cryo-microscope. Plos One, 15, 2020
|
|
5MK2
| |
8H3B
| Crystal structure of antibody scFv against M2e Influenza peptide | 分子名称: | GLYCEROL, Single Chain Variable Fragment | 著者 | Kumar, U, Madni, Z.K, Gaur, V, Salunke, D.M. | 登録日 | 2022-10-08 | 公開日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | A structure and knowledge-based combinatorial approach to engineering universal scFv antibodies against influenza M2 protein. J.Biomed.Sci., 30, 2023
|
|
7KU3
| Data clustering and dynamics of chymotrypsinogen cluster 141 (cyan) structure | 分子名称: | Chymotrypsinogen A, SULFATE ION | 著者 | Nguyen, T, Phan, K.L, Kreitler, D.F, Andrews, L.C, Gabelli, S.B, Kozakov, D, Jakoncic, J, Sweet, R.M, Soares, A.S, Bernstein, H.J. | 登録日 | 2020-11-24 | 公開日 | 2021-03-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs. Acta Crystallogr D Struct Biol, 78, 2022
|
|
6YM0
| Crystal structure of the SARS-CoV-2 receptor binding domain in complex with CR3022 Fab (crystal form 1) | 分子名称: | Spike glycoprotein, heavy chain, light chain | 著者 | Huo, J, Zhao, Y, Ren, J, Zhou, D, Ginn, H.M, Fry, E.E, Owens, R, Stuart, D.I. | 登録日 | 2020-04-07 | 公開日 | 2020-04-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (4.36 Å) | 主引用文献 | Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike. Cell Host Microbe, 28, 2020
|
|
6YNG
| |
7KTZ
| Data clustering and dynamics of chymotrypsinogen cluster 131 (purple) structure | 分子名称: | Chymotrypsinogen A, SULFATE ION | 著者 | Nguyen, T, Phan, K.L, Kreitler, D.F, Andrews, L.C, Gabelli, S.B, Kozakov, D, Jakoncic, J, Sweet, R.M, Soares, A.S, Bernstein, H.J. | 登録日 | 2020-11-24 | 公開日 | 2021-03-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs. Acta Crystallogr D Struct Biol, 78, 2022
|
|
7KTY
| Data clustering and dynamics of chymotrypsinogen average structure | 分子名称: | Chymotrypsinogen A, SULFATE ION | 著者 | Nguyen, T, Phan, K.L, Kreitler, D.F, Andrews, L.C, Gabelli, S.B, Kozakov, D, Jakoncic, J, Shi, W, Sweet, R.M, Soares, A.S, Bernstein, H.J. | 登録日 | 2020-11-24 | 公開日 | 2021-03-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs. Acta Crystallogr D Struct Biol, 78, 2022
|
|
6FGF
| Crystal Structure of BAZ2A bromodomain in complex with 1-methylpyridinone compound 2 | 分子名称: | Bromodomain adjacent to zinc finger domain protein 2A, ~{N}-[3-[(4-fluorophenyl)carbonylamino]propyl]-1-methyl-6-oxidanylidene-pyridine-3-carboxamide | 著者 | Dalle Vedove, A, Spiliotopoulos, D, Lolli, G, Caflisch, A. | 登録日 | 2018-01-10 | 公開日 | 2018-05-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | Structural Analysis of Small-Molecule Binding to the BAZ2A and BAZ2B Bromodomains. ChemMedChem, 13, 2018
|
|