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PDB: 53266 件

4V4H
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Crystal structure of the bacterial ribosome from Escherichia coli in complex with the antibiotic kasugamyin at 3.5A resolution.
分子名称: (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, ...
著者Schuwirth, B.S, Vila-Sanjurjo, A, Cate, J.H.D.
登録日2006-08-04
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.46 Å)
主引用文献Structural analysis of kasugamycin inhibition of translation.
Nat.Struct.Mol.Biol., 13, 2006
4V8S
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Archaeal RNAP-DNA binary complex at 4.32Ang
分子名称: 5'-D(*AP*TP*AP*GP*AP*GP*TP*AP*TP*AP*AP*GP*AP*TP *AP*G)-3', 5'-D(*TP*CP*TP*TP*AP*TP*AP*CP*TP*CP*TP*AP*TP*CP)-3', DNA-DIRECTED RNA POLYMERASE, ...
著者Wojtas, M.N, Mogni, M, Millet, O, Bell, S.D, Abrescia, N.G.A.
登録日2012-07-12
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (4.323 Å)
主引用文献Structural and Functional Analyses of the Interaction of Archaeal RNA Polymerase with DNA.
Nucleic Acids Res., 40, 2012
4W93
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Human pancreatic alpha-amylase in complex with montbretin A
分子名称: CALCIUM ION, CHLORIDE ION, Montbretin A, ...
著者Williams, L.K, Caner, S, Brayer, G.D.
登録日2014-08-27
公開日2015-07-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.352 Å)
主引用文献The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif.
Nat.Chem.Biol., 11, 2015
7C2O
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Crystal structure of the R-specific Carbonyl Reductase from Candida parapsilosis ATCC 7330 without DTT
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, R-specific carbonyl reductase, ...
著者Vinaykumar, K, KanalElamparithi, B, Chaudhury, D, Gunasekaran, K, Chadha, A.
登録日2020-05-08
公開日2020-05-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the R-specific Carbonyl Reductase from Candida parapsilosis ATCC 7330 without DTT
To Be Published
6KQ8
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328 K cryoEM structure of Sso-KARI in complex with Mg2+
分子名称: Ketol-acid reductoisomerase, MAGNESIUM ION
著者Chen, C.Y, Chang, Y.C, Lin, B.L, Huang, C.H, Tsai, M.D.
登録日2019-08-16
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Temperature-Resolved Cryo-EM Uncovers Structural Bases of Temperature-Dependent Enzyme Functions.
J.Am.Chem.Soc., 141, 2019
7RC3
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Aeronamide N-methyltransferase, AerE (Y137F)
分子名称: ASPARTIC ACID, CALCIUM ION, HEXAETHYLENE GLYCOL, ...
著者Cogan, D.P, Reyes, R, Nair, S.K.
登録日2021-07-07
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins.
Proc.Natl.Acad.Sci.USA, 119, 2022
1VRZ
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Helix turn helix motif
分子名称: ACETATE ION, DE NOVO DESIGNED 21 RESIDUE PEPTIDE
著者Rudresh, Ramakumar, S, Ramagopal, U.A, Inai, Y, Sahal, D.
登録日2005-10-14
公開日2005-11-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献De Novo Design and Characterization of a Helical Hairpin Eicosapeptide; Emergence of an Anion Receptor in the Linker Region.
Structure, 12, 2004
7RC4
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Aeronamide N-methyltransferase, AerE (D141A)
分子名称: CALCIUM ION, HEXAETHYLENE GLYCOL, Methyltransferase family protein, ...
著者Cogan, D.P, Reyes, R, Nair, S.K.
登録日2021-07-07
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins.
Proc.Natl.Acad.Sci.USA, 119, 2022
6DLU
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Cryo-EM of the GMPPCP-bound human dynamin-1 polymer assembled on the membrane in the constricted state
分子名称: Dynamin-1, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
著者Kong, L, Wang, H, Fang, S, Canagarajah, B, Kehr, A.D, Rice, W.J, Hinshaw, J.E.
登録日2018-06-02
公開日2018-08-01
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Cryo-EM of the dynamin polymer assembled on lipid membrane.
Nature, 560, 2018
1HSQ
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SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA
分子名称: PHOSPHOLIPASE C-GAMMA (SH3 DOMAIN)
著者Kohda, D, Hatanaka, H, Odaka, M, Inagaki, F.
登録日1994-06-13
公開日1994-08-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the SH3 domain of phospholipase C-gamma.
Cell(Cambridge,Mass.), 72, 1993
7RC5
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Aeronamide N-methyltransferase, AerE (N231A)
分子名称: CALCIUM ION, Methyltransferase family protein, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Cogan, D.P, Reyes, R, Nair, S.K.
登録日2021-07-07
公開日2022-03-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins.
Proc.Natl.Acad.Sci.USA, 119, 2022
6KP2
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BU of 6kp2 by Molmil
Quadruple mutant plasmodium falciparum dihydrofolate reductase complexed with B10042
分子名称: 5-(3-chlorophenyl)-6-(3-phenoxypropyl)pyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, GLYCEROL, ...
著者Vanichtanankul, J, Vitsupakorn, D.
登録日2019-08-14
公開日2019-12-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.973 Å)
主引用文献6-Hydrophobic aromatic substituent pyrimethamine analogues as potential antimalarials for pyrimethamine-resistant Plasmodium falciparum.
Bioorg.Med.Chem., 27, 2019
1I04
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BU of 1i04 by Molmil
CRYSTAL STRUCTURE OF MOUSE MAJOR URINARY PROTEIN-I FROM MOUSE LIVER
分子名称: MAJOR URINARY PROTEIN I
著者Timm, D.E, Baker, L.J, Mueller, H, Zidek, L, Novotny, M.V.
登録日2001-01-28
公開日2001-02-14
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of pheromone binding to mouse major urinary protein (MUP-I)
Protein Sci., 10, 2001
7RQY
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Cryo-EM structure of the full-length TRPV1 with RTx at 25 degrees Celsius, in an open state, class B
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, Transient receptor potential cation channel subfamily V member 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate, ...
著者Kwon, D.H, Suo, Y, Lee, S.-Y.
登録日2021-08-08
公開日2022-06-01
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis.
Nat Commun, 13, 2022
7RQU
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Cryo-EM structure of the full-length TRPV1 with RTx at 4 degrees Celsius, in a closed state, class I
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol, SODIUM ION, ...
著者Kwon, D.H, Suo, Y, Lee, S.-Y.
登録日2021-08-08
公開日2022-06-01
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis.
Nat Commun, 13, 2022
6KOT
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Quadruple mutant (N51I+C59R+S108N+I164L) plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with B12128 and NADPH
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 4-[3-[[2,6-bis(azanyl)-5-(3-chlorophenyl)pyrimidin-4-yl]methoxy]phenoxy]butanoic acid, Bifunctional dihydrofolate reductase-thymidylate synthase, ...
著者Vanichtanankul, J, Vitsupakorn, D.
登録日2019-08-13
公開日2019-12-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.149 Å)
主引用文献6-Hydrophobic aromatic substituent pyrimethamine analogues as potential antimalarials for pyrimethamine-resistant Plasmodium falciparum.
Bioorg.Med.Chem., 27, 2019
7RQV
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Cryo-EM structure of the full-length TRPV1 with RTx at 4 degrees Celsius, in an intermediate-closed state, class II
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ...
著者Kwon, D.H, Suo, Y, Lee, S.-Y.
登録日2021-08-08
公開日2022-06-01
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Vanilloid-dependent TRPV1 opening trajectory from cryoEM ensemble analysis.
Nat Commun, 13, 2022
1I1H
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CRYSTAL STRUCTURE ANALYSIS OF PRECORRIN-8X METHYLMUTASE COMPLEX WITH HYDROGENOBYRINIC ACID
分子名称: HYDROGENOBYRINIC ACID, PRECORRIN-8X METHYLMUTASE
著者Shipman, L.W, Li, D, Roessner, C.A, Scott, A.I, Sacchettini, J.C.
登録日2001-02-01
公開日2001-07-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of precorrin-8x methyl mutase.
Structure, 9, 2001
1W3D
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NMR structure of the peripheral-subunit binding domain of Bacillus stearothermophilus E2p
分子名称: DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE
著者Allen, M.D, Broadhurst, R.W, Solomon, R.G, Perham, R.N.
登録日2004-07-14
公開日2004-07-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Interaction of the E2 and E3 Components of the Pyruvate Dehydrogenase Multienzyme Complex of Bacillus Stearothermophilus. Use of a Truncated Protein Domain in NMR Spectroscopy
FEBS J., 272, 2005
6KVP
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S. aureus FtsZ in complex with 3-(1-(5-bromo-4-(4-(trifluoromethyl)phenyl)oxazol-2-yl)ethoxy)-2,6-difluorobenzamide (compound 2)
分子名称: 3-[(1R)-1-[5-bromanyl-4-[4-(trifluoromethyl)phenyl]-1,3-oxazol-2-yl]ethoxy]-2,6-bis(fluoranyl)benzamide, CALCIUM ION, Cell division protein FtsZ, ...
著者Ferrer-Gonzalez, E, Fujita, J, Yoshizawa, T, Nelson, J.M, Pilch, A.J, Hillman, E, Ozawa, M, Kuroda, N, Parhi, A.K, LaVoie, E.J, Matsumura, H, Pilch, D.S.
登録日2019-09-05
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure-Guided Design of a Fluorescent Probe for the Visualization of FtsZ in Clinically Important Gram-Positive and Gram-Negative Bacterial Pathogens.
Sci Rep, 9, 2019
7RM8
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Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide
分子名称: Isoform 4 of PDZ and LIM domain protein 7,Sorting nexin-17 fusion
著者Healy, M.D, Collins, B.M, Mobli, M.
登録日2021-07-26
公開日2022-08-31
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins.
Structure, 30, 2022
7R9B
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Crystal structure of Triosephosphate isomerase from Candidatus Roizmanbacteria
分子名称: PHOSPHATE ION, Triosephosphate isomerase
著者Vickers, C.J, Patrick, W.M, Fraga, D.
登録日2021-06-28
公開日2022-07-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Triosephosphate isomerase from Candidatus Roizmanbacteria
To Be Published
1VOP
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CONSERVED RNA COMPONENT OF THE PEPTIDYL TRANSFERASE CENTER, NMR, 33 STRUCTURES
分子名称: 23S RIBOSOMAL RNA
著者Puglisi, E.V, Puglisi, J.D.
登録日1997-08-30
公開日1997-12-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of a conserved RNA component of the peptidyl transferase centre.
Nat.Struct.Biol., 4, 1997
4U1K
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HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-15
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
6DHA
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Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Hydroxy Pioglitazone (M-IV)
分子名称: Hydroxy Pioglitazone (M-IV), Peroxisome proliferator-activated receptor gamma, nonanoic acid
著者Shang, J, Mosure, S.A, Kojetin, D.J.
登録日2018-05-18
公開日2019-03-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPAR gamma Drug Pioglitazone.
J. Med. Chem., 62, 2019

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件を2024-09-04に公開中

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