4B9W
 
 | | Structure of extended Tudor domain TD3 from mouse TDRD1 in complex with MILI peptide containing dimethylarginine 45. | | Descriptor: | GLYCEROL, PIWI-LIKE PROTEIN 2, TUDOR DOMAIN-CONTAINING PROTEIN 1 | | Authors: | Mathioudakis, N, Palencia, A, Kadlec, J, Round, A, Tripsianes, K, Sattler, M, Pillai, R.S, Cusack, S. | | Deposit date: | 2012-09-08 | | Release date: | 2012-10-17 | | Last modified: | 2019-04-10 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors.
Rna, 18, 2012
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2J1K
 | | CAV-2 fibre head in complex with CAR D1 | | Descriptor: | COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR, FIBER PROTEIN | | Authors: | Seiradake, E, Lortat-Jacob, H, Billet, O, Kremer, E.J, Cusack, S. | | Deposit date: | 2006-08-14 | | Release date: | 2006-09-05 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor.
J.Biol.Chem., 281, 2006
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3ZIU
 | | Crystal structure of Mycoplasma mobile Leucyl-tRNA Synthetase with Leu-AMS in the active site | | Descriptor: | 5'-O-(L-leucylsulfamoyl)adenosine, GLYCEROL, LEUCYL-TRNA SYNTHETASE | | Authors: | Li, L, Palencia, A, Lukk, T, Li, Z, Luthey-Schulten, Z.A, Cusack, S, Martinis, S.A, Boniecki, M.T. | | Deposit date: | 2013-01-10 | | Release date: | 2013-02-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Leucyl-tRNA Synthetase Editing Domain Functions as a Molecular Rheostat to Control Codon Ambiguity in Mycoplasma Pathogens.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4AQ7
 | | Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucyl-adenylate analogue in the aminoacylation conformation | | Descriptor: | E. COLI TRNALEU UAA ISOACCEPTOR, LEUCINE, LEUCINE--TRNA LIGASE, ... | | Authors: | Palencia, A, Crepin, T, Vu, M.T, Lincecum Jr, T.L, Martinis, S.A, Cusack, S. | | Deposit date: | 2012-04-13 | | Release date: | 2012-06-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase
Nat.Struct.Mol.Biol., 19, 2012
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4ARC
 | | Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and leucine in the editing conformation | | Descriptor: | LEUCINE, LEUCINE--TRNA LIGASE, MAGNESIUM ION, ... | | Authors: | Palencia, A, Crepin, T, Vu, M.T, Lincecum Jr, T.L, Martinis, S.A, Cusack, S. | | Deposit date: | 2012-04-23 | | Release date: | 2012-06-13 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase
Nat.Struct.Mol.Biol., 19, 2012
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2GMO
 | | NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2 | | Descriptor: | Polymerase basic protein 2 | | Authors: | Boudet, J, Tarendeau, F, Guilligay, D, Mas, P, Bougault, C.M, Cusack, S, Simorre, J.-P, Hart, D.J. | | Deposit date: | 2006-04-07 | | Release date: | 2007-02-27 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit.
Nat.Struct.Mol.Biol., 14, 2007
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1EAJ
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1E8O
 | | Core of the Alu domain of the mammalian SRP | | Descriptor: | 7SL RNA, SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN, SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN, ... | | Authors: | Weichenrieder, O, Wild, K, Strub, K, Cusack, S. | | Deposit date: | 2000-09-28 | | Release date: | 2000-11-08 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure and Assembly of the Alu Domain of the Mammalian Signal Recognition Particle
Nature, 408, 2000
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2I4M
 | | Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with ProAMS | | Descriptor: | '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE, Proline-tRNA ligase | | Authors: | Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S. | | Deposit date: | 2006-08-22 | | Release date: | 2006-10-24 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
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4AWH
 | | Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with rUMP | | Descriptor: | MANGANESE (II) ION, POLYMERASE PA, URIDINE-5'-MONOPHOSPHATE | | Authors: | Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. | | Deposit date: | 2012-06-03 | | Release date: | 2012-08-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
Plos Pathog., 8, 2012
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4AVL
 | | Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with dTMP | | Descriptor: | MANGANESE (II) ION, POLYMERASE PA, THYMIDINE-5'-PHOSPHATE | | Authors: | Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H.J, Ruigrok, R.W.H, Cusack, S. | | Deposit date: | 2012-05-28 | | Release date: | 2012-08-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
Plos Pathog., 8, 2012
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4AVG
 | | Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 2 | | Descriptor: | (Z)-4-[4-[(4-chlorophenyl)methyl]-1-(cyclohexylmethyl)piperidin-4-yl]-2-oxidanyl-4-oxidanylidene-but-2-enoic acid, MANGANESE (II) ION, POLYMERASE PA | | Authors: | Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. | | Deposit date: | 2012-05-25 | | Release date: | 2012-08-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
Plos Pathog., 8, 2012
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4AWG
 | | Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 3 | | Descriptor: | (2Z)-4-[(3S)-1-benzyl-3-(4-chlorobenzyl)piperidin-3-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, POLYMERASE PA, ... | | Authors: | Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. | | Deposit date: | 2012-06-03 | | Release date: | 2012-08-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
Plos Pathog., 8, 2012
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4AWF
 | | Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with 2 4-dioxo-4-phenylbutanoic acid DPBA | | Descriptor: | 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, POLYMERASE PA | | Authors: | Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. | | Deposit date: | 2012-06-03 | | Release date: | 2012-08-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.
Plos Pathog., 8, 2012
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4BGP
 | | Crystal structure of La Crosse virus nucleoprotein | | Descriptor: | GLYCEROL, NUCLEOPROTEIN, SULFATE ION | | Authors: | Reguera, J, Malet, H, Weber, F, Cusack, S. | | Deposit date: | 2013-03-28 | | Release date: | 2013-04-24 | | Last modified: | 2013-05-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Basis for Encapsidation of Genomic RNA by La Crosse Orthobunyavirus Nucleoprotein
Proc.Natl.Acad.Sci.USA, 110, 2013
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1F5W
 | | DIMERIC STRUCTURE OF THE COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR D1 DOMAIN | | Descriptor: | COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR, SULFATE ION | | Authors: | van Raaij, M.J, Chouin, E, van der Zandt, H, Bergelson, J.M, Cusack, S. | | Deposit date: | 2000-06-18 | | Release date: | 2000-11-08 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution.
Structure Fold.Des., 8, 2000
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2IYK
 | | Crystal structure of the UPF2-interacting domain of nonsense mediated mRNA decay factor UPF1 | | Descriptor: | REGULATOR OF NONSENSE TRANSCRIPTS 1, ZINC ION | | Authors: | Kadlec, J, Guilligay, D, Ravelli, R.B, Cusack, S. | | Deposit date: | 2006-07-18 | | Release date: | 2006-08-30 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Crystal Structure of the Upf2-Interacting Domain of Nonsense-Mediated Mrna Decay Factor Upf1.
RNA, 12, 2006
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2J12
 | | Ad37 fibre head in complex with CAR D1 | | Descriptor: | CALCIUM ION, COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR, FIBER PROTEIN | | Authors: | Seiradake, E, Lortat-Jacob, H, Billet, O, Kremer, E.J, Cusack, S. | | Deposit date: | 2006-08-08 | | Release date: | 2006-08-29 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor.
J.Biol.Chem., 281, 2006
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2J2J
 | | Canine adenovirus fibre head at 1.5 A resolution | | Descriptor: | FIBER PROTEIN | | Authors: | Seiradake, E, Lortat-Jacob, H, Billet, O, Kremer, E.J, Cusack, S. | | Deposit date: | 2006-08-16 | | Release date: | 2006-09-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor.
J.Biol.Chem., 281, 2006
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2J3M
 | | PROLYL-TRNA SYNTHETASE FROM ENTEROCOCCUS FAECALIS COMPLEXED WITH ATP, manganese and prolinol | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PROLYL-TRNA SYNTHETASE, ... | | Authors: | Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S. | | Deposit date: | 2006-08-22 | | Release date: | 2006-10-11 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a Cis-Editing Domain.
Structure, 14, 2006
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2V9S
 | | Second LRR domain of human Slit2 | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SLIT HOMOLOG 2 PROTEIN N-PRODUCT | | Authors: | Morlot, C, Cusack, S, McCarthy, A.A. | | Deposit date: | 2007-08-25 | | Release date: | 2007-09-25 | | Last modified: | 2014-11-05 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Insights Into the Slit-Robo Complex.
Proc.Natl.Acad.Sci.USA, 104, 2007
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2I4O
 | | Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with ATP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Proline-tRNA ligase | | Authors: | Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S. | | Deposit date: | 2006-08-22 | | Release date: | 2006-10-24 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
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2I4N
 | | Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with CysAMS | | Descriptor: | 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE, Proline-tRNA ligase | | Authors: | Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S. | | Deposit date: | 2006-08-22 | | Release date: | 2006-10-24 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
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1E8S
 | | Alu domain of the mammalian SRP (potential Alu retroposition intermediate) | | Descriptor: | 7SL RNA, 88-MER, EUROPIUM (III) ION, ... | | Authors: | Weichenrieder, O, Wild, K, Strub, K, Cusack, S. | | Deposit date: | 2000-09-29 | | Release date: | 2000-11-08 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structure and Assembly of the Alu Domain of the Mammalian Signal Recognition Particle
Nature, 408, 2000
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2XGT
 | | Asparaginyl-tRNA synthetase from Brugia malayi complexed with the sulphamoyl analogue of asparaginyl-adenylate | | Descriptor: | 5'-O-[N-(L-ASPARAGINYL)SULFAMOYL]ADENOSINE, ASPARAGINYL-TRNA SYNTHETASE, CYTOPLASMIC, ... | | Authors: | Crepin, T, Haertlein, M, Kron, M, Cusack, S. | | Deposit date: | 2010-06-07 | | Release date: | 2010-12-15 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A Hybrid Structural Model of the Complete Brugia Malayi Cytoplasmic Asparaginyl-tRNA Synthetase.
J.Mol.Biol., 405, 2011
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