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PDB: 270 件
4A3G
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RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid
分子名称: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
著者Cheung, A.C.M, Sainsbury, S, Cramer, P.
登録日2011-09-30
公開日2012-02-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
7ONU
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BU of 7onu by Molmil
Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-Tyr
分子名称: 3-hydroxyacyl-CoA dehydrogenase type-2, MAGNESIUM ION, Mitochondrial Precursor tRNA-Tyr, ...
著者Bhatta, A, Dienemann, C, Cramer, P, Hillen, H.S.
登録日2021-05-26
公開日2021-08-11
最終更新日2021-09-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of RNA processing by human mitochondrial RNase P.
Nat.Struct.Mol.Biol., 28, 2021
3R84
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Structure of the Mediator head subcomplex Med11/22
分子名称: Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 22
著者Seizl, M, Lariviere, L, Pfaffenender, T, Wenzeck, L, Cramer, P.
登録日2011-03-23
公開日2011-04-27
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization.
Nucleic Acids Res., 39, 2011
1YKH
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Structure of the mediator MED7/MED21 (Med7/Srb7) subcomplex
分子名称: RNA polymerase II holoenzyme component SRB7, RNA polymerase II mediator complex protein MED7
著者Baumli, S, Hoeppner, S, Cramer, P.
登録日2005-01-18
公開日2005-02-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A conserved mediator hinge revealed in the structure of the MED7.MED21 (Med7.Srb7) heterodimer.
J.Biol.Chem., 280, 2005
6RID
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BU of 6rid by Molmil
Structure of Vaccinia Virus DNA-dependent RNA polymerase elongation complex
分子名称: DNA-dependent RNA polymerase subunit rpo132, DNA-dependent RNA polymerase subunit rpo147, DNA-dependent RNA polymerase subunit rpo18, ...
著者Hillen, H.S, Bartuli, J, Grimm, C, Dienemann, C, Bedenk, K, Szalar, A, Fischer, U, Cramer, P.
登録日2019-04-23
公開日2019-12-18
最終更新日2019-12-25
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes.
Cell, 179, 2019
4A3I
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RNA Polymerase II binary complex with DNA
分子名称: 5'-D(*GP*GP*CP*AP*CP*AP*AP*CP*TP*GP*CP*GP*GP*CP*T)-3', DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ...
著者Cheung, A.C.M, Sainsbury, S, Cramer, P.
登録日2011-09-30
公開日2012-02-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
1ZP2
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Structure of the Mediator subunit cyclin C
分子名称: RNA polymerase II holoenzyme cyclin-like subunit
著者Hoeppner, S, Baumli, S, Cramer, P.
登録日2005-05-16
公開日2005-07-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the Mediator Subunit Cyclin C and its Implications for CDK8 Function.
J.Mol.Biol., 350, 2005
1SZA
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BU of 1sza by Molmil
The RNA polymerase II CTD in mRNA processing: beta-turn recognition and beta-spiral model
分子名称: CTD-peptide, PCF11 protein
著者Meinhart, A, Cramer, P.
登録日2004-04-05
公開日2004-07-13
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recognition of RNA polymerase II carboxy-terminal domain by 3'-RNA-processing factors.
Nature, 430, 2004
7NKY
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RNA Polymerase II-Spt4/5-nucleosome-FACT structure
分子名称: Chromatin elongation factor SPT4, DNA (138-MER), DNA (148-MER), ...
著者Farnung, L, Ochmann, M, Engeholm, M, Cramer, P.
登録日2021-02-19
公開日2021-07-07
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Nat.Struct.Mol.Biol., 28, 2021
3TJ1
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BU of 3tj1 by Molmil
Crystal Structure of RNA Polymerase I Transcription Initiation Factor Rrn3
分子名称: RNA polymerase I-specific transcription initiation factor RRN3
著者Blattner, C, Jennebach, S, Herzog, F, Mayer, A, Cheung, A.C.M, Witte, G, Lorenzen, K, Hopfner, K.-P, Heck, A.J.R, Aebersold, R, Cramer, P.
登録日2011-08-23
公開日2011-09-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth.
Genes Dev., 25, 2011
7OKX
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Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite structure)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ...
著者Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P.
登録日2021-05-18
公開日2021-07-14
最終更新日2021-09-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Allosteric transcription stimulation by RNA polymerase II super elongation complex.
Mol.Cell, 81, 2021
7OKY
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Structure of active transcription elongation complex Pol II-DSIF-ELL2-EAF1(composite structure)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ...
著者Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P.
登録日2021-05-18
公開日2021-07-14
最終更新日2021-09-01
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Allosteric transcription stimulation by RNA polymerase II super elongation complex.
Mol.Cell, 81, 2021
7OL0
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BU of 7ol0 by Molmil
Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ...
著者Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P.
登録日2021-05-18
公開日2021-07-14
最終更新日2021-09-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Allosteric transcription stimulation by RNA polymerase II super elongation complex.
Mol.Cell, 81, 2021
7OYG
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Dimeric form of SARS-CoV-2 RNA-dependent RNA polymerase
分子名称: RNA (5'-R(P*CP*UP*AP*CP*GP*CP*AP*GP*UP*G)-3'), RNA (5'-R(P*UP*GP*CP*AP*CP*UP*GP*CP*GP*UP*AP*G)-3'), SARS-CoV-2 RNA-dependent RNA polymerase (nsp12), ...
著者Jochheim, F.A, Tegunov, D, Hillen, H.S, Schmitzova, J, Kokic, G, Dienemann, C, Cramer, P.
登録日2021-06-24
公開日2021-08-25
最終更新日2021-09-01
実験手法ELECTRON MICROSCOPY (5.5 Å)
主引用文献The structure of a dimeric form of SARS-CoV-2 polymerase
Communications Biology, 4, 2021
7OPD
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BU of 7opd by Molmil
Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5)
分子名称: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ...
著者Kokic, G, Cramer, P.
登録日2021-05-31
公開日2021-10-06
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
7OO3
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Pol II-CSB-CSA-DDB1-UVSSA (Structure1)
分子名称: CSB element, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ...
著者Kokic, G, Cramer, P.
登録日2021-05-26
公開日2021-10-06
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
7OOP
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BU of 7oop by Molmil
Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3)
分子名称: DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ...
著者Kokic, G, Cramer, P.
登録日2021-05-28
公開日2021-10-06
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
7OPC
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Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4)
分子名称: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ...
著者Kokic, G, Cramer, P.
登録日2021-05-31
公開日2021-10-13
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
7OOB
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Pol II-CSB-CSA-DDB1-UVSSA-ADPBeF3 (Structure2)
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA damage-binding protein 1, ...
著者Kokic, G, Cramer, P.
登録日2021-05-27
公開日2021-10-13
最終更新日2021-10-27
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
7NKX
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RNA polymerase II-Spt4/5-nucleosome-Chd1 structure
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromatin elongation factor SPT4, ...
著者Farnung, L, Ochmann, M, Engeholm, M, Cramer, P.
登録日2021-02-19
公開日2021-08-25
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Nat.Struct.Mol.Biol., 28, 2021
7PKS
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Structural basis of Integrator-mediated transcription regulation
分子名称: DNA Template, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ...
著者Fianu, I, Chen, Y, Dienemann, C, Cramer, P.
登録日2021-08-26
公開日2021-12-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of Integrator-mediated transcription regulation.
Science, 374, 2021
3NR5
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Crystal structure of human Maf1
分子名称: Repressor of RNA polymerase III transcription MAF1 homolog
著者Ringel, R, Vannini, A, Kusser, A.G, Berninghausen, O, Kassavetis, G.A, Cramer, P.
登録日2010-06-30
公開日2010-10-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Molecular Basis of RNA Polymerase III Transcription Repression by Maf1
Cell(Cambridge,Mass.), 143, 2010
3K1F
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Crystal structure of RNA Polymerase II in complex with TFIIB
分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
著者Kostrewa, D, Zeller, M.E, Armache, K.-J, Seizl, M, Leike, K, Thomm, M, Cramer, P.
登録日2009-09-27
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献RNA polymerase II-TFIIB structure and mechanism of transcription initiation.
Nature, 462, 2009
2C5Z
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Structure and CTD binding of the Set2 SRI domain
分子名称: SET DOMAIN PROTEIN 2
著者Vojnic, E, Simon, B, Strahl, B.D, Sattler, M, Cramer, P.
登録日2005-11-03
公開日2005-11-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription.
J. Biol. Chem., 281, 2006
1RO0
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Bifunctional DNA primase/polymerase domain of ORF904 from the archaeal plasmid pRN1- Triple mutant F50M/L107M/L110M SeMet remote
分子名称: ORF904, ZINC ION
著者Lipps, G, Weinzierl, A.O, von Scheven, G, Buchen, C, Cramer, P.
登録日2003-12-01
公開日2004-01-27
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a bifunctional DNA primase-polymerase
Nat.Struct.Mol.Biol., 11, 2004

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