1AWO
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1JEG
| Solution structure of the SH3 domain from C-terminal Src Kinase complexed with a peptide from the tyrosine phosphatase PEP | Descriptor: | HEMATOPOIETIC CELL PROTEIN-TYROSINE PHOSPHATASE 70Z-PEP, TYROSINE-PROTEIN KINASE CSK | Authors: | Ghose, R, Shekhtman, A, Goger, M.J, Ji, H, Cowburn, D. | Deposit date: | 2001-06-17 | Release date: | 2001-10-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A novel, specific interaction involving the Csk SH3 domain and its natural ligand. Nat.Struct.Biol., 8, 2001
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7SGT
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5TVZ
| Solution NMR structure of Saccharomyces cerevisiae Pom152 Ig-like repeat, residues 718-820 | Descriptor: | Nucleoporin POM152 | Authors: | Dutta, K, Sampathkumar, P, Cowburn, D, Almo, S.C, Rout, M.P, Fernandez-Martinez, J. | Deposit date: | 2016-11-10 | Release date: | 2017-02-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex. Structure, 25, 2017
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6AX5
| RPT1 region of INI1/SNF5/SMARCB1_HUMAN - SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1. | Descriptor: | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | Authors: | Girvin, M.E, Cahill, S.M, Harris, R, Cowburn, D, Spira, M, Wu, X, Prakash, R, Bernowitz, M, Almo, S.C, Kalpana, G.V. | Deposit date: | 2017-09-06 | Release date: | 2017-10-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication. Nat Commun, 12, 2021
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6DSL
| Consensus engineered intein (Cat) with atypical split site | Descriptor: | Consensus engineered intein CatC, Consensus engineered intein CatN | Authors: | Sekar, G, Stevens, A.J, Muir, T.W, Cowburn, D. | Deposit date: | 2018-06-14 | Release date: | 2018-09-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | An Atypical Mechanism of Split Intein Molecular Recognition and Folding. J. Am. Chem. Soc., 140, 2018
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4HDI
| Crystal Structure of 3E5 IgG3 FAB from mus musculus | Descriptor: | Ig heavy chain V region RF, Ig gamma-3 chain C region, Kappa light chain variable region, ... | Authors: | Janda, A, Eryilmaz, E, Kim, J, Cordero, R.J.B, Cowburn, D, Casadevall, A. | Deposit date: | 2012-10-02 | Release date: | 2013-04-17 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.449 Å) | Cite: | Global structures of IgG isotypes expressing identical variable regions. Mol.Immunol., 56, 2013
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1Z66
| NMR solution structure of domain III of E-protein of tick-borne Langat flavivirus (no RDC restraints) | Descriptor: | Major envelope protein E | Authors: | Mukherjee, M, Dutta, K, White, M.A, Cowburn, D, Fox, R.O. | Deposit date: | 2005-03-21 | Release date: | 2006-03-28 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | NMR solution structure and backbone dynamics of domain III of the E protein of tick-borne Langat flavivirus suggests a potential site for molecular recognition. Protein Sci., 15, 2006
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1XBH
| A BETA-HAIRPIN MIMIC FROM FCERI-ALPHA-CYCLO(L-262) | Descriptor: | PROTEIN (CYCLO(L-262)) | Authors: | Mcdonnell, J.M, Fushman, D, Cahill, S.M, Sutton, B.J, Cowburn, D. | Deposit date: | 1999-02-17 | Release date: | 1999-02-21 | Last modified: | 2024-10-30 | Method: | SOLUTION NMR | Cite: | Solution Structures of FceRI Alpha-Chain Mimics: A Beta-Hairpin Peptide and Its Retroenantiomer J.Am.Chem.Soc., 119, 1997
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2L6E
| NMR Structure of the monomeric mutant C-terminal domain of HIV-1 Capsid in complex with stapled peptide Inhibitor | Descriptor: | Capsid protein p24, NYAD-13 stapled peptide inhibitor | Authors: | Bhattacharya, S, Zhang, H, Debnath, A.K, Cowburn, D. | Deposit date: | 2010-11-18 | Release date: | 2010-12-29 | Last modified: | 2024-10-16 | Method: | SOLUTION NMR | Cite: | Solution structure of a hydrocarbon stapled peptide inhibitor in complex with monomeric C-terminal domain of HIV-1 capsid. J.Biol.Chem., 283, 2008
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1G84
| THE SOLUTION STRUCTURE OF THE C EPSILON2 DOMAIN FROM IGE | Descriptor: | IMMUNOGLOBULIN E | Authors: | McDonnell, J.M, Cowburn, D, Gould, H.J, Sutton, B.J, Calvert, R, Beavil, R.E, Beavil, A.J, Henry, A.J. | Deposit date: | 2000-11-16 | Release date: | 2001-05-16 | Last modified: | 2024-10-30 | Method: | SOLUTION NMR | Cite: | The structure of the IgE Cepsilon2 domain and its role in stabilizing the complex with its high-affinity receptor FcepsilonRIalpha. Nat.Struct.Biol., 8, 2001
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2GG1
| NMR solution structure of domain III of the E-protein of tick-borne Langat flavivirus (includes RDC restraints) | Descriptor: | Genome polyprotein | Authors: | Mukherjee, M, Dutta, K, White, M.A, Cowburn, D, Fox, R.O. | Deposit date: | 2006-03-23 | Release date: | 2006-04-25 | Last modified: | 2023-11-29 | Method: | SOLUTION NMR | Cite: | NMR solution structure and backbone dynamics of domain III of the E protein of tick-borne Langat flavivirus suggests a potential site for molecular recognition. Protein Sci., 15, 2006
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2K6X
| Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1- Induced Compacted Structure | Descriptor: | RNA polymerase sigma factor rpoD | Authors: | Schwartz, E.C, Shekhtman, A, Dutta, K, Pratt, M.R, Cowburn, D, Darst, S, Muir, T.W. | Deposit date: | 2008-07-28 | Release date: | 2008-10-28 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region 1.1 - Induced Compacted Structure Chem.Biol., 15, 2008
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3EAZ
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3EAC
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3BRH
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2M0V
| Complex structure of C-terminal CFTR peptide and extended PDZ2 domain from NHERF1 | Descriptor: | C-terminal CFTR peptide, Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | Authors: | Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z. | Deposit date: | 2012-11-06 | Release date: | 2013-04-24 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1. J.Mol.Biol., 425, 2013
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2M0T
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2M0U
| Complex structure of C-terminal CFTR peptide and extended PDZ1 domain from NHERF1 | Descriptor: | C-terminal CFTR peptide, Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | Authors: | Bhattacharya, S, Ju, J.H, Cowburn, D, Bu, Z. | Deposit date: | 2012-11-06 | Release date: | 2013-04-24 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1. J.Mol.Biol., 425, 2013
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2GGR
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1DDB
| STRUCTURE OF MOUSE BID, NMR, 20 STRUCTURES | Descriptor: | PROTEIN (BID) | Authors: | Mcdonnell, J.M, Fushman, D, Milliman, C, Korsmeyer, S.J, Cowburn, D. | Deposit date: | 1999-02-19 | Release date: | 1999-08-30 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists. Cell(Cambridge,Mass.), 96, 1999
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2KJD
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1AB2
| THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE SRC HOMOLOGY 2 DOMAIN OF C-ABL | Descriptor: | C-ABL TYROSINE KINASE SH2 DOMAIN | Authors: | Overduin, M, Rios, C.B, Mayer, B.J, Baltimore, D, Cowburn, D. | Deposit date: | 1993-07-19 | Release date: | 1994-01-31 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Three-dimensional solution structure of the src homology 2 domain of c-abl. Cell(Cambridge,Mass.), 70, 1992
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2KRG
| Solution Structure of human sodium/ hydrogen exchange regulatory factor 1(150-358) | Descriptor: | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | Authors: | Bhattacharya, S, Dai, Z, Li, J, Baxter, S, Callaway, D.J.E, Cowburn, D, Bu, Z. | Deposit date: | 2009-12-17 | Release date: | 2009-12-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | A conformational switch in the scaffolding protein NHERF1 controls autoinhibition and complex formation. J.Biol.Chem., 285, 2010
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1AWE
| HUMAN SOS1 PLECKSTRIN HOMOLOGY (PH) DOMAIN, NMR, 20 STRUCTURES | Descriptor: | SOS1 | Authors: | Zheng, J, Cowburn, D. | Deposit date: | 1997-10-01 | Release date: | 1998-02-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The solution structure of the pleckstrin homology domain of human SOS1. A possible structural role for the sequential association of diffuse B cell lymphoma and pleckstrin homology domains. J.Biol.Chem., 272, 1997
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