5TNV
 
 | | Crystal Structure of a Xylose isomerase-like TIM barrel Protein from Mycobacterium smegmatis in Complex with Magnesium | | Descriptor: | AP endonuclease, family protein 2, MAGNESIUM ION | | Authors: | Cook, W.J, Fedorov, A.A, Fedorov, E.V, Huang, H, Bonanno, J.B, Gerlt, J.A, Almo, S.C. | | Deposit date: | 2016-10-14 | | Release date: | 2016-11-09 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.04 Å) | | Cite: | Crystal Structure of a Xylose isomerase-like TIM barrel Protein from Mycobacterium smegmatis in Complex with Magnesium
To Be Published
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1AAR
 | | STRUCTURE OF A DIUBIQUITIN CONJUGATE AND A MODEL FOR INTERACTION WITH UBIQUITIN CONJUGATING ENZYME (E2) | | Descriptor: | DI-UBIQUITIN | | Authors: | Cook, W.J, Jeffrey, L.C, Carson, M, Chen, Z, Pickart, C.M. | | Deposit date: | 1992-04-17 | | Release date: | 1993-10-31 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of a diubiquitin conjugate and a model for interaction with ubiquitin conjugating enzyme (E2).
J.Biol.Chem., 267, 1992
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3CLN
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2INT
 | | CRYSTAL STRUCTURE OF RECOMBINANT HUMAN INTERLEUKIN-4 | | Descriptor: | INTERLEUKIN-4 | | Authors: | Walter, M.R, Cook, W.J, Zhao, B.G, Cameron Junior, R, Ealick, S.E, Walter Junior, R.L, Reichert, P, Nagabhushan, T.L, Trotta, P.P, Bugg, C.E. | | Deposit date: | 1993-07-22 | | Release date: | 1994-01-31 | | Last modified: | 2019-08-14 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal structure of recombinant human interleukin-4.
J.Biol.Chem., 267, 1992
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1UBQ
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1F8X
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2TPT
 | | STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE | | Descriptor: | SULFATE ION, THYMIDINE PHOSPHORYLASE | | Authors: | Pugmire, M.J, Cook, W.J, Jasanoff, A, Walter, M.R, Ealick, S.E. | | Deposit date: | 1997-11-24 | | Release date: | 1999-03-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.
J.Mol.Biol., 281, 1998
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4TSS
 | | TOXIC SHOCK SYNDROME TOXIN-1: TETRAGONAL P4(1)2(1)2 CRYSTAL FORM | | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1, ZINC ION | | Authors: | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | | Deposit date: | 1996-12-11 | | Release date: | 1997-12-24 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
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1TPT
 | | THREE-DIMENSIONAL STRUCTURE OF THYMIDINE PHOSPHORYLASE FROM ESCHERICHIA COLI AT 2.8 ANGSTROMS RESOLUTION | | Descriptor: | SULFATE ION, THYMIDINE PHOSPHORYLASE, THYMINE | | Authors: | Walter, M.R, Cook, W.J, Cole, L.B, Short, S.A, Koszalka, G.W, Krenitsky, T.A, Ealick, S.E. | | Deposit date: | 1990-06-14 | | Release date: | 1991-07-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 A resolution.
J.Biol.Chem., 265, 1990
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3TSS
 | | TOXIC SHOCK SYNDROME TOXIN-1 TETRAMUTANT, P2(1) CRYSTAL FORM | | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | | Authors: | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | | Deposit date: | 1996-12-11 | | Release date: | 1997-12-24 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
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1HIG
 | | THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT HUMAN INTERFERON-GAMMA. | | Descriptor: | INTERFERON-GAMMA | | Authors: | Ealick, S.E, Cook, W.J, Vijay-Kumar, S, Carson, M, Nagabhushan, T.L, Trotta, P.P, Bugg, C.E. | | Deposit date: | 1991-10-03 | | Release date: | 1992-04-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Three-dimensional structure of recombinant human interferon-gamma.
Science, 252, 1991
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1UCH
 | | DEUBIQUITINATING ENZYME UCH-L3 (HUMAN) AT 1.8 ANGSTROM RESOLUTION | | Descriptor: | UBIQUITIN C-TERMINAL HYDROLASE UCH-L3 | | Authors: | Johnston, S.C, Larsen, C.N, Cook, W.J, Wilkinson, K.D, Hill, C.P. | | Deposit date: | 1997-10-06 | | Release date: | 1998-01-28 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 A resolution.
EMBO J., 16, 1997
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5TSS
 | | TOXIC SHOCK SYNDROME TOXIN-1: ORTHORHOMBIC P222(1) CRYSTAL FORM | | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | | Authors: | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | | Deposit date: | 1996-12-11 | | Release date: | 1997-12-24 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
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1ULA
 | | APPLICATION OF CRYSTALLOGRAPHIC AND MODELING METHODS IN THE DESIGN OF PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS | | Descriptor: | PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION | | Authors: | Ealick, S.E, Rule, S.A, Carter, D.C, Greenhough, T.J, Babu, Y.S, Cook, W.J, Habash, J, Helliwell, J.R, Stoeckler, J.D, Parksjunior, R.E, Chen, S.-F, Bugg, C.E. | | Deposit date: | 1991-11-05 | | Release date: | 1993-01-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors.
Proc.Natl.Acad.Sci.USA, 88, 1991
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1ULB
 | | APPLICATION OF CRYSTALLOGRAPHIC AND MODELING METHODS IN THE DESIGN OF PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITORS | | Descriptor: | GUANINE, PURINE NUCLEOSIDE PHOSPHORYLASE, SULFATE ION | | Authors: | Ealick, S.E, Rule, S.A, Carter, D.C, Greenhough, T.J, Babu, Y.S, Cook, W.J, Habash, J, Helliwell, J.R, Stoeckler, J.D, Parksjunior, R.E, Chen, S.-F, Bugg, C.E. | | Deposit date: | 1991-11-05 | | Release date: | 1993-01-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Application of crystallographic and modeling methods in the design of purine nucleoside phosphorylase inhibitors.
Proc.Natl.Acad.Sci.USA, 88, 1991
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1CSG
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2PMS
 | | Crystal structure of the complex of human lactoferrin N-lobe and lactoferrin-binding domain of pneumococcal surface protein A | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | | Authors: | Chattopadhyay, D, Senkovich, O, Cook, W.J. | | Deposit date: | 2007-04-23 | | Release date: | 2007-06-19 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | Structure of a Complex of Human Lactoferrin N-lobe with Pneumococcal Surface Protein A Provides Insight into Microbial Defense Mechanism.
J.Mol.Biol., 370, 2007
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2TSS
 | | TOXIC SHOCK SYNDROME TOXIN-1 FROM STAPHYLOCOCCUS AUREUS: ORTHORHOMBICC222(1) CRYSTAL FORM | | Descriptor: | TOXIC SHOCK SYNDROME TOXIN-1 | | Authors: | Prasad, G.S, Radhakrishnan, R, Mitchell, D.T, Earhart, C.A, Dinges, M.M, Cook, W.J, Schlivert, P.M, Ohlendorf, D.H. | | Deposit date: | 1996-12-04 | | Release date: | 1997-12-24 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Protein Sci., 6, 1997
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1F8Y
 | | CRYSTAL STRUCTURE ANALYSIS OF NUCLEOSIDE 2-DEOXYRIBOSYLTRANSFERASE COMPLEXED WITH 5-METHYL-2'-DEOXYPSEUDOURIDINE | | Descriptor: | 2'-deoxy-1-methyl-pseudouridine, NUCLEOSIDE 2-DEOXYRIBOSYLTRANSFERASE | | Authors: | Armstrong, S.R, Cook, W.J, Short, S.A, Ealick, S.E. | | Deposit date: | 2000-07-05 | | Release date: | 2000-08-09 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structures of nucleoside 2-deoxyribosyltransferase in native and ligand-bound forms reveal architecture of the active site.
Structure, 4, 1996
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1AZY
 | | STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE | | Descriptor: | THYMIDINE PHOSPHORYLASE | | Authors: | Pugmire, M.J, Cook, W.J, Jasanoff, A, Walter, M.R, Ealick, S.E. | | Deposit date: | 1997-11-24 | | Release date: | 1999-01-13 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.
J.Mol.Biol., 281, 1998
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4ND3
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4ND4
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1A9T
 | | BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-DEAZAINOSINE AND PHOSPHATE | | Descriptor: | 1-O-phosphono-alpha-D-ribofuranose, HYPOXANTHINE, PURINE NUCLEOSIDE PHOSPHORYLASE | | Authors: | Mao, C, Cook, W.J, Zhou, M, Fedorov, A.A, Almo, S.C, Ealick, S.E. | | Deposit date: | 1998-04-10 | | Release date: | 1998-06-17 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry, 37, 1998
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4ND5
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4ND2
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