4J2X
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![BU of 4j2x by Molmil](/molmil-images/mine/4j2x) | CSL (RBP-Jk) with corepressor KyoT2 bound to DNA | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3', 5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3', ... | Authors: | Collins, K.J, Kovall, R.A. | Deposit date: | 2013-02-05 | Release date: | 2013-11-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structure and Function of the CSL-KyoT2 Corepressor Complex: A Negative Regulator of Notch Signaling. Structure, 22, 2014
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2KYE
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![BU of 2kye by Molmil](/molmil-images/mine/2kye) | Solution structure of the pseudouridine modified P6.1 hairpin of human telomerase RNA | Descriptor: | RNA (5'-R(*GP*AP*GP*AP*GP*(PSU)P*(PSU)P*GP*GP*GP*CP*(PSU)P*CP*(PSU)P*C)-3') | Authors: | Kim, N.-K, Theimer, C.A, Mitchell, J.R, Collins, K, Feigon, J. | Deposit date: | 2010-05-25 | Release date: | 2010-06-30 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA. Nucleic Acids Res., 38, 2010
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8B3Z
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![BU of 8b3z by Molmil](/molmil-images/mine/8b3z) | |
7BGB
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![BU of 7bgb by Molmil](/molmil-images/mine/7bgb) | The H/ACA RNP lobe of human telomerase | Descriptor: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | Authors: | Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K. | Deposit date: | 2021-01-06 | Release date: | 2021-04-28 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structure of human telomerase holoenzyme with bound telomeric DNA. Nature, 593, 2021
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7BG9
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![BU of 7bg9 by Molmil](/molmil-images/mine/7bg9) | The catalytic core lobe of human telomerase in complex with a telomeric DNA substrate | Descriptor: | DNA (5'-D(P*TP*TP*AP*GP*GP*G)-3'), Histone H2A, Histone H2B, ... | Authors: | Nguyen, T.H.D, Ghanim, G.E, Fountain, A.J, van Roon, A.M.M, Rangan, R, Das, R, Collins, K. | Deposit date: | 2021-01-06 | Release date: | 2021-04-28 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of human telomerase holoenzyme with bound telomeric DNA. Nature, 593, 2021
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8UW3
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![BU of 8uw3 by Molmil](/molmil-images/mine/8uw3) | Human LINE-1 retrotransposon ORF2 protein engaged with template RNA in elongation state | Descriptor: | Complementary DNA, LINE-1 retrotransposable element ORF2 protein, THYMIDINE-5'-TRIPHOSPHATE, ... | Authors: | Thawani, A, Florez Ariza, A.J, Collins, K, Nogales, E. | Deposit date: | 2023-11-06 | Release date: | 2023-12-20 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Template and target-site recognition by human LINE-1 in retrotransposition. Nature, 626, 2024
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8SH4
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![BU of 8sh4 by Molmil](/molmil-images/mine/8sh4) | Crystal structure of the tRNA (m1G37) methyltransferase apoenzyme from Anaplasma phagocytophilum | Descriptor: | GLYCEROL, tRNA (guanine-N(1)-)-methyltransferase | Authors: | Jannotta, C, Edele, D, Levanti, D, Carson, M, Prucha, G, Caesar, J, Picchiello, C, Collins, K, Garland, E, Handley-Pendleton, J, Hernandez, V, Leffler, S, Williams, D, Stojanoff, V, Perez, A, Halloran, J, Bolen, R. | Deposit date: | 2023-04-13 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of the m1G37 tRNA methyltransferase apoenzyme from Anaplasma phagocytophilum To Be Published
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6PEY
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![BU of 6pey by Molmil](/molmil-images/mine/6pey) | MTHFR with mutation Asp120Ala | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Methylenetetrahydrofolate reductase | Authors: | Gallagher, E.L, Gurney, L.A, Frasco, F.G, Trimmer, E, Bolen, R.L, Collins, K, Garland, E, Halloran, J, Handley-Pendelton, J, Hernandez, V, Leffler, S, Perez, A, Soares, A, Stojanoff, V, Williams, D. | Deposit date: | 2019-06-21 | Release date: | 2019-09-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.88 Å) | Cite: | Examination of Asp120Ala a Chemically Important Novel Mutation in the Enzyme Mthylenetetrahydrofolate Reductase To be published
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2LSL
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![BU of 2lsl by Molmil](/molmil-images/mine/2lsl) | Solution structure of the C-terminal domain of Tetrahymena telomerase protein p65 | Descriptor: | Telomerase associated protein p65 | Authors: | Singh, M, Wang, Z, Koo, B, Patel, A, Cascio, D, Collins, K, Feigon, J. | Deposit date: | 2012-05-01 | Release date: | 2012-06-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mol.Cell, 47, 2012
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3ZGQ
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![BU of 3zgq by Molmil](/molmil-images/mine/3zgq) | Crystal structure of human interferon-induced protein IFIT5 | Descriptor: | DI(HYDROXYETHYL)ETHER, INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 5 | Authors: | Katibah, G.E, Lee, H.J, Huizar, J.P, Vogan, J.M, Alber, T, Collins, K. | Deposit date: | 2012-12-19 | Release date: | 2013-01-23 | Last modified: | 2013-03-06 | Method: | X-RAY DIFFRACTION (2.203 Å) | Cite: | TRNA Binding, Structure, and Localization of the Human Interferon-Induced Protein Ifit5. Mol.Cell, 49, 2013
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2M21
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![BU of 2m21 by Molmil](/molmil-images/mine/2m21) | Solution structure of the Tetrahymena telomerase RNA stem IV terminal loop | Descriptor: | 5'-R(*GP*GP*CP*GP*AP*UP*AP*CP*AP*CP*UP*AP*UP*UP*UP*AP*UP*CP*GP*CP*C)-3' | Authors: | Cash, D.D, Richards, R.J, Wu, H, Trantirek, L, O'Connor, C.M, Feigon, J, Collins, K. | Deposit date: | 2012-12-11 | Release date: | 2013-03-20 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function. Rna, 12, 2006
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4ERD
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![BU of 4erd by Molmil](/molmil-images/mine/4erd) | Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 in complex with stem IV of telomerase RNA | Descriptor: | 5'-R(P*GP*GP*UP*CP*GP*AP*CP*AP*UP*CP*UP*UP*CP*GP*GP*AP*UP*GP*GP*AP*CP*C)-3', POTASSIUM ION, Telomerase associated protein p65 | Authors: | Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J. | Deposit date: | 2012-04-19 | Release date: | 2012-06-20 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.589 Å) | Cite: | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mol.Cell, 47, 2012
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4EYT
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![BU of 4eyt by Molmil](/molmil-images/mine/4eyt) | Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 | Descriptor: | SULFATE ION, Telomerase associated protein p65 | Authors: | Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J. | Deposit date: | 2012-05-01 | Release date: | 2012-06-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65. Mol.Cell, 47, 2012
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