4CAK
| Three-dimensional reconstruction of intact human integrin alphaIIbbeta3 in a phospholipid bilayer nanodisc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-IIb, ... | Authors: | Choi, W.S, Rice, W.J, Stokes, D.L, Coller, B.S. | Deposit date: | 2013-10-08 | Release date: | 2013-10-30 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (20.5 Å) | Cite: | Three-Dimensional Reconstruction of Intact Human Integrin Alphaiibbeta3; New Implications for Activation-Dependent Ligand Binding. Blood, 122, 2013
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1TYE
| Structural basis for allostery in integrins and binding of ligand-mimetic therapeutics to the platelet receptor for fibrinogen | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, CALCIUM ION, ... | Authors: | Xiao, T, Takagi, J, Coller, B.S, Wang, J.-H, Springer, T.A. | Deposit date: | 2004-07-07 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics Nature, 432, 2004
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6V4P
| Structure of the integrin AlphaIIbBeta3-Abciximab complex | Descriptor: | Abciximab, heavy chain, light chain, ... | Authors: | Nesic, D, Zhang, Y, Spasic, A, Li, J, Provasi, D, Filizola, M, Walz, T, Coller, B.S. | Deposit date: | 2019-11-28 | Release date: | 2020-02-05 | Last modified: | 2020-03-11 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-Electron Microscopy Structure of the alpha IIb beta 3-Abciximab Complex. Arterioscler Thromb Vasc Biol., 40, 2020
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