3IJG
| Macrophage Migration Inhibitory Factor (MIF) Bound to the (R)-Stereoisomer of AV1013 | Descriptor: | (2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one, CHLORIDE ION, Macrophage migration inhibitory factor | Authors: | Crichlow, G.V, Cho, Y, Lolis, E.J. | Deposit date: | 2009-08-04 | Release date: | 2010-06-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc.Natl.Acad.Sci.USA, 107, 2010
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8IEC
| Cryo-EM structure of miniGo-scFv16 of GPR156-miniGo-scFv16 complex (local refine) | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | Authors: | Shin, J, Park, J, Cho, Y. | Deposit date: | 2023-02-15 | Release date: | 2024-02-14 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Constitutive activation mechanism of a class C GPCR. Nat.Struct.Mol.Biol., 31, 2024
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8IED
| Cryo-EM structure of GPR156-miniGo-scFv16 complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | Authors: | Shin, J, Park, J, Cho, Y. | Deposit date: | 2023-02-15 | Release date: | 2024-02-14 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Constitutive activation mechanism of a class C GPCR. Nat.Struct.Mol.Biol., 31, 2024
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8IEQ
| Cryo-EM structure of G-protein free GPR156 | Descriptor: | Probable G-protein coupled receptor 156, [(2R)-3-[(E)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate | Authors: | Shin, J, Park, J, Cho, Y. | Deposit date: | 2023-02-15 | Release date: | 2024-02-14 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Constitutive activation mechanism of a class C GPCR. Nat.Struct.Mol.Biol., 31, 2024
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8IEI
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8IEB
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8IEP
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1GH6
| RETINOBLASTOMA POCKET COMPLEXED WITH SV40 LARGE T ANTIGEN | Descriptor: | Large T antigen, Retinoblastoma-associated protein | Authors: | Kim, H.Y, Cho, Y. | Deposit date: | 2000-11-15 | Release date: | 2001-11-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen. EMBO J., 20, 2001
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1M2K
| Sir2 homologue F159A mutant-ADP ribose complex | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | Authors: | Chang, J, Cho, Y. | Deposit date: | 2002-06-24 | Release date: | 2003-04-08 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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1M2G
| Sir2 homologue-ADP ribose complex | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | Authors: | Chang, J, Cho, Y. | Deposit date: | 2002-06-24 | Release date: | 2003-04-08 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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1M2J
| Sir2 homologue H80N mutant-ADP ribose complex | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | Authors: | Chang, J, Cho, Y. | Deposit date: | 2002-06-24 | Release date: | 2003-04-08 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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1M2N
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1M2H
| Sir2 homologue S24A mutant-ADP ribose complex | Descriptor: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | Authors: | Chang, J, Cho, Y. | Deposit date: | 2002-06-24 | Release date: | 2003-04-08 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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1N4M
| Structure of Rb tumor suppressor bound to the transactivation domain of E2F-2 | Descriptor: | Retinoblastoma Pocket, Transcription factor E2F2 | Authors: | Lee, C, Chang, J.H, Lee, H.S, Cho, Y. | Deposit date: | 2002-10-31 | Release date: | 2003-01-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor GENES DEV., 16, 2002
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1N6A
| Structure of SET7/9 | Descriptor: | S-ADENOSYLMETHIONINE, SET domain-containing protein 7 | Authors: | Kwon, T.W, Chang, J.H, Kwak, E, Lee, C.W, Joachimiak, A, Kim, Y.C, Lee, J, Cho, Y. | Deposit date: | 2002-11-09 | Release date: | 2003-02-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet EMBO J., 22, 2003
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1N6C
| Structure of SET7/9 | Descriptor: | S-ADENOSYLMETHIONINE, SET domain-containing protein 7 | Authors: | Kwon, T.W, Chang, J.H, Cho, Y. | Deposit date: | 2002-11-09 | Release date: | 2003-02-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet EMBO J., 22, 2003
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3B64
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3TAL
| Crystal structure of NurA with manganese | Descriptor: | DNA double-strand break repair protein nurA, GLYCEROL, MANGANESE (II) ION | Authors: | Chae, J, Kim, Y.C, Cho, Y. | Deposit date: | 2011-08-04 | Release date: | 2011-11-23 | Last modified: | 2013-07-03 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Crystal structure of the NurA-dAMP-Mn2+ complex Nucleic Acids Res., 40, 2012
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3TAZ
| Crystal structure of NurA bound to dAMP and manganese | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, DNA double-strand break repair protein nurA, GLYCEROL, ... | Authors: | Chae, J, Kim, Y.C, Cho, Y. | Deposit date: | 2011-08-04 | Release date: | 2011-11-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of the NurA-dAMP-Mn2+ complex Nucleic Acids Res., 40, 2012
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3TAI
| Crystal structure of NurA | Descriptor: | DNA double-strand break repair protein nurA, GLYCEROL | Authors: | Chae, J, Kim, Y.C, Cho, Y. | Deposit date: | 2011-08-04 | Release date: | 2011-11-23 | Last modified: | 2013-07-03 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Crystal structure of the NurA-dAMP-Mn2+ complex Nucleic Acids Res., 40, 2012
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4TUG
| Crystal structure of MjMre11-DNA2 complex | Descriptor: | DNA (5'-D(P*CP*TP*GP*TP*CP*CP*TP*AP*CP*GP*TP*GP*CP*CP*A)-3'), DNA (5'-D(P*GP*CP*AP*CP*GP*TP*AP*GP*GP*AP*CP*AP*GP*C)-3'), DNA double-strand break repair protein Mre11, ... | Authors: | Sung, S, Cho, Y. | Deposit date: | 2014-06-24 | Release date: | 2014-10-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | DNA end recognition by the Mre11 nuclease dimer: insights into resection and repair of damaged DNA. Embo J., 33, 2014
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1R6L
| Crystal Structure Of The tRNA Processing Enzyme Rnase pH From Pseudomonas Aeruginosa | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Ribonuclease PH, SULFATE ION | Authors: | Choi, J.M, Park, E.Y, Kim, J.H, Chang, S.K, Cho, Y. | Deposit date: | 2003-10-15 | Release date: | 2004-02-17 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Probing the functional importance of the hexameric ring structure of RNase PH J.BIOL.CHEM., 279, 2004
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1R6M
| Crystal Structure Of The tRNA Processing Enzyme Rnase pH From Pseudomonas Aeruginosa In Complex With Phosphate | Descriptor: | PHOSPHATE ION, Ribonuclease PH | Authors: | Choi, J.M, Park, E.Y, Kim, J.H, Chang, S.K, Cho, Y. | Deposit date: | 2003-10-15 | Release date: | 2004-02-17 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Probing the functional importance of the hexameric ring structure of RNase PH J.BIOL.CHEM., 279, 2004
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2KLO
| Structure of the Cdt1 C-terminal domain | Descriptor: | DNA replication factor Cdt1 | Authors: | Khayrutdinov, B.I, Bae, W.J, Yun, Y.M, Tsuyama, T, Kim, J.J, Hwang, E, Ryu, K.-S, Cheong, H.-K, Cheong, C, Karplus, P.A, Guntert, P, Tada, S, Jeon, Y.H, Cho, Y. | Deposit date: | 2009-07-06 | Release date: | 2009-10-13 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structure of the Cdt1 C-terminal domain: Conservation of the winged helix fold in replication licensing factors Protein Sci., 18, 2009
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2MJP
| STRUCTURE-BASED IDENTIFICATION OF THE BIOCHEMICAL FUNCTION OF A HYPOTHETICAL PROTEIN FROM METHANOCOCCUS JANNASCHII:MJ0226 | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PYROPHOSPHATASE | Authors: | Hwang, K.Y, Chung, J.H, Han, Y.S, Kim, S.H, Cho, Y, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 1999-01-27 | Release date: | 2000-01-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-based identification of a novel NTPase from Methanococcus jannaschii. Nat.Struct.Biol., 6, 1999
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