8TY1
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![BU of 8ty1 by Molmil](/molmil-images/mine/8ty1) | |
8G6I
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![BU of 8g6i by Molmil](/molmil-images/mine/8g6i) | Coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor VIII chimera from human and pig, NB33 heavy chain, ... | Authors: | Childers, K.C, Davulcu, O, Haynes, R.M, Lollar, P, Doering, C.B, Coxon, C.H, Spiegel, P.C. | Deposit date: | 2023-02-15 | Release date: | 2023-05-24 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (4.23 Å) | Cite: | Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor. Blood, 142, 2023
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7K66
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![BU of 7k66 by Molmil](/molmil-images/mine/7k66) | Structure of Blood Coagulation Factor VIII in Complex with an Anti-C1 Domain Pathogenic Antibody Inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2A9 heavy chain, ... | Authors: | Childers, K.C, Gish, J, Jarvis, L, Peters, S, Garrels, C, Smith, I.W, Spencer, H.T, Spiegel, P.C. | Deposit date: | 2020-09-18 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.92 Å) | Cite: | Structure of blood coagulation factor VIII in complex with an anti-C1 domain pathogenic antibody inhibitor. Blood, 137, 2021
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9D5D
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7S0P
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![BU of 7s0p by Molmil](/molmil-images/mine/7s0p) | Crystal structure of Porcine Factor VIII C2 Domain Bound to Phosphatidylserine | Descriptor: | Coagulation factor VIII, PHOSPHOSERINE | Authors: | Peters, S.C, Childers, K.C, Wo, S.W, Brison, C.M, Swanson, C.D, Spiegel, P.C. | Deposit date: | 2021-08-30 | Release date: | 2021-10-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Stable binding to phosphatidylserine-containing membranes requires conserved arginine residues in tandem C domains of blood coagulation factor VIII. Front Mol Biosci, 9, 2022
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7KBT
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![BU of 7kbt by Molmil](/molmil-images/mine/7kbt) | Factor VIII in complex with the anti-C2 domain antibody, G99 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Ronayne, E.K, Gish, J, Wilson, C, Peters, S, Spencer, H.T, Spiegel, P.C, Childers, K.C. | Deposit date: | 2020-10-02 | Release date: | 2020-11-18 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (4.15 Å) | Cite: | Structure of Blood Coagulation Factor VIII in Complex With an Anti-C2 Domain Non-Classical, Pathogenic Antibody Inhibitor Front Immunol, 12, 2021
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