6H35
| Myxococcus xanthus MglA bound to GDP and Pi with mixed inactive and active switch region conformations | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GUANOSINE-5'-DIPHOSPHATE, Mutual gliding-motility protein MglA, ... | 著者 | Varela, P.F, Galicia, C, Cherfils, J. | 登録日 | 2018-07-17 | 公開日 | 2019-12-04 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus. Nat Commun, 10, 2019
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6H5B
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5NLV
| Brag2 Sec7-PH (390-763) | 分子名称: | IQ motif and SEC7 domain-containing protein 1 | 著者 | Nawrotek, A, Cherfils, J. | 登録日 | 2017-04-05 | 公開日 | 2017-09-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5NLY
| Brag2 Sec7-PH (390-763), P212121 | 分子名称: | IQ motif and SEC7 domain-containing protein 1, PHOSPHATE ION | 著者 | Nawrotek, A, Cherfils, J. | 登録日 | 2017-04-05 | 公開日 | 2017-09-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Multiple interactions between an Arf/GEF complex and charged lipids determine activation kinetics on the membrane. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1OIX
| X-ray structure of the small G protein Rab11a in complex with GDP and Pi | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pasqualato, S, Senic-Matuglia, F, Renault, L, Goud, B, Salamero, J, Cherfils, J. | 登録日 | 2003-06-26 | 公開日 | 2005-01-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystallographic Evidence for Substrate-Assisted GTP Hydrolysis by a Small GTP Binding Protein Structure, 13, 2005
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6H17
| Myxococcus xanthus MglA bound to GTPgammaS | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Mutual gliding-motility protein MglA, ... | 著者 | Galicia, C, Cherfils, J. | 登録日 | 2018-07-11 | 公開日 | 2019-11-27 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.275 Å) | 主引用文献 | MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus. Nat Commun, 10, 2019
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6HJO
| Myxococcus xanthus MglA bound to GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Mutual gliding-motility protein MglA | 著者 | Varela, P.F, Cherfils, J. | 登録日 | 2018-09-04 | 公開日 | 2019-12-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus. Nat Commun, 10, 2019
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6HJH
| Myxococcus xanthus MglA bound to GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Mutual gliding-motility protein MglA | 著者 | Varela, P.F, Cherfils, J. | 登録日 | 2018-09-03 | 公開日 | 2019-12-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus. Nat Commun, 10, 2019
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6ER8
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5NWF
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5NV5
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1OIW
| X-ray structure of the small G protein Rab11a in complex with GTPgammaS | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, RAS-RELATED PROTEIN RAB-11A | 著者 | Pasqualato, S, Senic-Matuglia, F, Renault, L, Goud, B, Salamero, J, Cherfils, J. | 登録日 | 2003-06-26 | 公開日 | 2004-01-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The Structural Gdp/GTP Cycle of Rab11 Reveals a Novel Interface Involved in the Dynamics of Recycling Endosomes J.Biol.Chem., 279, 2004
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1OIV
| X-ray structure of the small G protein Rab11a in complex with GDP | 分子名称: | 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, RAS-RELATED PROTEIN RAB-11A, ... | 著者 | Pasqualato, S, Senic-Matuglia, F, Renault, L, Goud, B, Salamero, J, Cherfils, J. | 登録日 | 2003-06-26 | 公開日 | 2004-01-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | The Structural Gdp/GTP Cycle of Rab11 Reveals a Novel Interface Involved in the Dynamics of Recycling Endosomes J.Biol.Chem., 279, 2004
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2AN9
| Crystal Structure Of Oligomeric E.coli Guanylate Kinase In Complex With GDP | 分子名称: | GUANOSINE, GUANOSINE-5'-DIPHOSPHATE, Guanylate kinase, ... | 著者 | Hible, G, Renault, L, Schaeffer, F, Christova, P, Radulescu, A.Z, Evrin, C, Gilles, A.M, Cherfils, J. | 登録日 | 2005-08-11 | 公開日 | 2005-08-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase J.Mol.Biol., 352, 2005
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4BER
| Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein in complex with cytidine monophosphate | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, GLYCEROL, PHOSPHATE ION, ... | 著者 | Campanacci, V, Mukherjee, S, Roy, C.R, Cherfils, J. | 登録日 | 2013-03-12 | 公開日 | 2013-04-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of the Legionella Effector Ankx Reveals the Mechanism of Phosphocholine Transfer by the Fic Domain. Embo J., 32, 2013
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4BET
| Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein (inactive H229A mutant) in complex with cytidine-diphosphate-choline | 分子名称: | GLYCEROL, PHOSPHOCHOLINE TRANSFERASE ANKX, SULFATE ION, ... | 著者 | Campanacci, V, Mukherjee, S, Roy, C.R, Cherfils, J. | 登録日 | 2013-03-12 | 公開日 | 2013-04-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structure of the Legionella Effector Ankx Reveals the Mechanism of Phosphocholine Transfer by the Fic Domain. Embo J., 32, 2013
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2ANC
| Crystal Structure Of Unliganded Form Of Oligomeric E.coli Guanylate Kinase | 分子名称: | Guanylate kinase | 著者 | Hible, G, Renault, L, Schaeffer, F, Christova, P, Radulescu, A.Z, Evrin, C, Gilles, A.M, Cherfils, J. | 登録日 | 2005-08-11 | 公開日 | 2005-08-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase J.Mol.Biol., 352, 2005
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4C0A
| Arf1(Delta1-17)in complex with BRAG2 Sec7-PH domain | 分子名称: | ADP-RIBOSYLATION FACTOR 1, GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE, IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 1 | 著者 | Aizel, K, Biou, V, Navaza, J, Duarte, L, Campanacci, V, Cherfils, J, Zeghouf, M. | 登録日 | 2013-08-01 | 公開日 | 2013-09-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Integrated conformational and lipid-sensing regulation of endosomal ArfGEF BRAG2. PLoS Biol., 11, 2013
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2ANB
| Crystal Structure Of Oligomeric E.coli Guanylate Kinase In Complex With GMP | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, SULFATE ION | 著者 | Hible, G, Renault, L, Schaeffer, F, Christova, P, Radulescu, A.Z, Evrin, C, Gilles, A.M, Cherfils, J. | 登録日 | 2005-08-11 | 公開日 | 2005-08-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase J.Mol.Biol., 352, 2005
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4D7Q
| Crystal structure of a chimeric protein with the Sec7 domain of Legionella pneumophila RalF and the capping domain of Rickettsia prowazekii RalF | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Folly-Klan, M, Sancerne, B, Alix, E, Roy, C.R, Cherfils, J, Campanacci, V. | 登録日 | 2014-11-27 | 公開日 | 2015-01-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | On the Use of Legionella/Rickettsia Chimeras to Investigate the Structure and Regulation of Rickettsia Effector Ralf. J.Struct.Biol., 189, 2015
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2BEF
| CRYSTAL STRUCTURE OF NDP KINASE COMPLEXED WITH MG, ADP, AND BEF3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | 著者 | Xu, Y.W, Cherfils, J. | 登録日 | 1998-05-26 | 公開日 | 1998-08-12 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | AlF3 mimics the transition state of protein phosphorylation in the crystal structure of nucleoside diphosphate kinase and MgADP. Proc.Natl.Acad.Sci.USA, 94, 1997
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6FNE
| Structure of human Brag2 (Sec7-PH domains) with the inhibitor Bragsin bound to the PH domain | 分子名称: | (2~{S})-6-methyl-5-nitro-2-(trifluoromethyl)-2,3-dihydrochromen-4-one, IQ motif and SEC7 domain-containing protein 1, NONAETHYLENE GLYCOL | 著者 | Nawrotek, A, Zeghouf, M, Cherfils, J. | 登録日 | 2018-02-03 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | PH-domain-binding inhibitors of nucleotide exchange factor BRAG2 disrupt Arf GTPase signaling. Nat.Chem.Biol., 15, 2019
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4A4P
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6H7E
| GEF regulatory domain | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cDNA FLJ56134, ... | 著者 | Ferrandez, Y, Cherfils, J, Peurois, F. | 登録日 | 2018-07-31 | 公開日 | 2020-02-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Membranes prime the RapGEF EPAC1 to transduce cAMP signaling. Nat Commun, 14, 2023
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4D7R
| Crystal structure of a chimeric protein with the Sec7 domain of Rickettsia prowazekii RalF and the capping domain of Legionella pneumophila RalF | 分子名称: | PROLINE/BETAINE TRANSPORTER, RALF | 著者 | Folly-Klan, M, Sancerne, B, Alix, E, Roy, C.R, Cherfils, J, Campanacci, V. | 登録日 | 2014-11-27 | 公開日 | 2015-01-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | On the Use of Legionella/Rickettsia Chimeras to Investigate the Structure and Regulation of Rickettsia Effector Ralf. J.Struct.Biol., 189, 2015
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