1D0V
 
 | | CRYSTAL STRUCTURE OF NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE (COBT) FROM SALMONELLA TYPHIMURIUM COMPLEXED WITH ITS REACTION PRODUCTS DETERMINED TO 1.9 A RESOLUTION | | 分子名称: | ALPHA-RIBAZOLE-5'-PHOSPHATE, NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE, NICOTINIC ACID | | 著者 | Cheong, C.-G, Escalante-Semerena, J.C, Rayment, I. | | 登録日 | 1999-09-14 | | 公開日 | 1999-12-29 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The three-dimensional structures of nicotinate mononucleotide:5,6- dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella typhimurium complexed with 5,6-dimethybenzimidazole and its reaction products determined to 1.9 A resolution.
Biochemistry, 38, 1999
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1D0S
 | | CRYSTAL STRUCTURE OF NICOTINATE MONONUCLEOTIDE : 5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE (COBT) FROM SALMONELLA TYPHIMURIUM COMPLEXED WITH 5, 6-DIMETHYLBENZIMIDAZOLE | | 分子名称: | 5,6-DIMETHYLBENZIMIDAZOLE, NICOTINATE MONONUCLEOTIDE:5,6-DIMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSFERASE, PHOSPHATE ION | | 著者 | Cheong, C.-G, Escalante-Semerena, J.C, Rayment, I. | | 登録日 | 1999-09-14 | | 公開日 | 1999-12-29 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The three-dimensional structures of nicotinate mononucleotide:5,6- dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella typhimurium complexed with 5,6-dimethybenzimidazole and its reaction products determined to 1.9 A resolution.
Biochemistry, 38, 1999
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1JHQ
 | | Three-dimensional Structure of CobT in Complex with Reaction Products of 5-methoxybenzimidazole and NaMN | | 分子名称: | N1-(5'-PHOSPHO-ALPHA-RIBOSYL)-5-METHOXYBENZIMIDAZOLE, NICOTINIC ACID, Nicotinate Mononucleotide:5,6-Dimethylbenzimidazole Phosphoribosyltransferase | | 著者 | Cheong, C.G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2001-06-28 | | 公開日 | 2001-10-18 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural investigation of the biosynthesis of alternative lower ligands for cobamides by nicotinate mononucleotide: 5,6-dimethylbenzimidazole phosphoribosyltransferase from Salmonella enterica.
J.Biol.Chem., 276, 2001
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1P4R
 | | Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD | | 分子名称: | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Bifunctional purine biosynthesis protein PURH, N-[(S)-(4-{[(2-AMINO-4-HYDROXYQUINAZOLIN-6-YL)(DIHYDROXY)-LAMBDA~4~-SULFANYL]AMINO}PHENYL)(HYDROXY)METHYL]-L-GLUTAMIC ACID, ... | | 著者 | Cheong, C.-G, Greasley, S.E, Horton, P.A, Beardsley, G.P, Wilson, I.A. | | 登録日 | 2003-04-23 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates
J.Biol.Chem., 279, 2004
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1PL0
 | | Crystal structure of human ATIC in complex with folate-based inhibitor, BW2315U89UC | | 分子名称: | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, Bifunctional purine biosynthesis protein PURH, N-(4-{[(2-AMINO-4-OXO-3,4-DIHYDROQUINAZOLIN-6-YL)AMINO]SULFONYL}BENZOYL)GLUTAMIC ACID, ... | | 著者 | Cheong, C.G, Greasley, S.E, Horton, P.A, Beardsley, G.P, Wilson, I.A. | | 登録日 | 2003-06-06 | | 公開日 | 2004-04-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structures of Human Bifunctional Enzyme Aminoimidazole-4-carboxamide Ribonucleotide Transformylase/IMP Cyclohydrolase in Complex with Potent Sulfonyl-containing Antifolates.
J.Biol.Chem., 279, 2004
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1RAU
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1L5K
 | | Crystal Structure of CobT complexed with N1-(5'-phosphoribosyl)-benzimidazole and nicotinate | | 分子名称: | 1-ALPHA-D-RIBOFURANOSYL-BENZIMIAZOLE-5'-PHOSPHATE, NICOTINIC ACID, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-07 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural studies of the L-threonine-O-3-phosphate decarboxylase
(CobD) enzyme from Salmonella enterica: the apo, substrate, and
product-aldimine complexes.
Biochemistry, 41, 2002
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1L5M
 | | Crystal Structure of CobT complexed with N7-(5'-phosphoribosyl)-2-aminopurine and nicotinate | | 分子名称: | 7-ALPHA-D-RIBOFURANOSYL-2-AMINOPURINE-5'-PHOSPHATE, NICOTINIC ACID, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-07 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural studies of the L-threonine-O-3-phosphate decarboxylase
(CobD) enzyme from Salmonella enterica: the apo, substrate, and
product-aldimine complexes.
Biochemistry, 41, 2002
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1LC7
 | | Crystal Structure of L-Threonine-O-3-phosphate Decarboxylase from S. enterica complexed with a substrate | | 分子名称: | L-Threonine-O-3-Phosphate Decarboxylase, PHOSPHATE ION, PHOSPHOTHREONINE | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-04-05 | | 公開日 | 2002-06-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural studies of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica: the apo, substrate, and product-aldimine complexes.
Biochemistry, 41, 2002
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1L5F
 | | Crystal Structure of CobT complexed with benzimidazole | | 分子名称: | BENZIMIDAZOLE, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, PHOSPHATE ION | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-06 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural studies of the L-threonine-O-3-phosphate decarboxylase
(CobD) enzyme from Salmonella enterica: the apo, substrate, and
product-aldimine complexes.
Biochemistry, 41, 2002
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1LC5
 | | Crystal Structure of L-Threonine-O-3-phosphate Decarboxylase from S. enterica in its apo state | | 分子名称: | L-Threonine-O-3-Phosphate Decarboxylase, PHOSPHATE ION | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-04-05 | | 公開日 | 2002-06-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Structural studies of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica: the apo, substrate, and product-aldimine complexes.
Biochemistry, 41, 2002
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1L5N
 | | Crystal Structure of CobT complexed with imidazole | | 分子名称: | IMIDAZOLE, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, PHOSPHATE ION | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-07 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural studies of the L-threonine-O-3-phosphate decarboxylase
(CobD) enzyme from Salmonella enterica: the apo, substrate, and
product-aldimine complexes.
Biochemistry, 41, 2002
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1LC8
 | | Crystal Structure of L-Threonine-O-3-phosphate Decarboxylase from S. enterica complexed with its reaction intermediate | | 分子名称: | L-Threonine-O-3-Phosphate Decarboxylase, {3-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-PROPYL}-PHOSPHONIC ACID | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-04-05 | | 公開日 | 2002-06-28 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural studies of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica: the apo, substrate, and product-aldimine complexes.
Biochemistry, 41, 2002
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1L5L
 | | Crystal Structure of CobT complexed with N7-(5'-phosphoribosyl)purine and nicotinate | | 分子名称: | 7-ALPHA-D-RIBOFURANOSYL-PURINE-5'-PHOSPHATE, NICOTINIC ACID, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-07 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural studies of the L-threonine-O-3-phosphate decarboxylase
(CobD) enzyme from Salmonella enterica: the apo, substrate, and
product-aldimine complexes.
Biochemistry, 41, 2002
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1L4N
 | | Crystal Structure of CobT complexed with 2-aminophenol | | 分子名称: | 2-AMINOPHENOL, NICOTINIC ACID, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, ... | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-06 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural studies of the L-threonine-O-3-phosphate decarboxylase
(CobD) enzyme from Salmonella enterica: the apo, substrate, and
product-aldimine complexes.
Biochemistry, 41, 2002
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1L4E
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1L4B
 | | Crystal Structure of CobT in apo state | | 分子名称: | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, PHOSPHATE ION | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-04 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Capture of a labile substrate by expulsion of water molecules from the active site of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella enterica.
J.Biol.Chem., 277, 2002
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1L4G
 | | Crystal Structure of CobT complexed with 4-methylcatechol and nicotinate mononucleotide | | 分子名称: | 4-METHYLCATECHOL, NICOTINATE MONONUCLEOTIDE, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-06 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Capture of a labile substrate by expulsion of water molecules from the active site of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella enterica.
J.Biol.Chem., 277, 2002
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1L5O
 | | Crystal Structure of CobT complexed with 3,4-dimethylphenol and nicotinate mononucleotide | | 分子名称: | 3,4-DIMETHYLPHENOL, NICOTINATE MONONUCLEOTIDE, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-07 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Capture of a labile substrate by expulsion of water molecules from the active site of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella enterica.
J.Biol.Chem., 277, 2002
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1L4K
 | | Crystal Structure of CobT complexed with 3,4-dimethylaniline and nicotinate mononucleotide | | 分子名称: | 3,4-DIMETHYLANILINE, NICOTINATE MONONUCLEOTIDE, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-06 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Capture of a labile substrate by expulsion of water molecules from the active site of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella enterica.
J.Biol.Chem., 277, 2002
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1L4F
 | | The crystal structure of CobT complexed with 4,5-dimethyl-1,2-phenylenediamine and nicotinate mononucleotide | | 分子名称: | 4,5-DIMETHYL-1,2-PHENYLENEDIAMINE, NICOTINATE MONONUCLEOTIDE, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-06 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Capture of a labile substrate by expulsion of water molecules from the active site of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella enterica.
J.Biol.Chem., 277, 2002
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1L4L
 | | Crystal Structure of CobT complexed with 2,5-dimethylaniline and nicotinate mononucleotide | | 分子名称: | 2,5-DIMETHYLANILINE, NICOTINATE MONONUCLEOTIDE, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-06 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Capture of a labile substrate by expulsion of water molecules from the active site of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella enterica.
J.Biol.Chem., 277, 2002
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1L4M
 | | Crystal Structure of CobT complexed with 2-amino-p-cresol and nicotinate mononucleotide | | 分子名称: | 2-AMINO-P-CRESOL, NICOTINATE MONONUCLEOTIDE, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-06 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Capture of a labile substrate by expulsion of water molecules from the active site of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella enterica.
J.Biol.Chem., 277, 2002
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1L4H
 | | Crystal Structure of CobT complexed with indole and nicotinate mononucleotide | | 分子名称: | INDOLE, NICOTINATE MONONUCLEOTIDE, Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2002-03-06 | | 公開日 | 2002-09-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Capture of a labile substrate by expulsion of water molecules from the active site of nicotinate mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase (CobT) from Salmonella enterica.
J.Biol.Chem., 277, 2002
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1JHA
 | | Structural Investigation of the Biosynthesis of Alternative Lower Ligands for Cobamides by Nicotinate Mononucleotide:5,6-Dimethylbenzimidazole Phosphoribosyltransferase (CobT) from Salmonella enterica | | 分子名称: | ALPHA-ADENOSINE MONOPHOSPHATE, NICOTINIC ACID, Nicotinate Mononucleotide:5,6-Dimethylbenzimidazole Phosphoribosyltransferase | | 著者 | Cheong, C.-G, Escalante-Semerena, J, Rayment, I. | | 登録日 | 2001-06-27 | | 公開日 | 2001-09-26 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural investigation of the biosynthesis of alternative lower ligands for cobamides by nicotinate mononucleotide: 5,6-dimethylbenzimidazole phosphoribosyltransferase from Salmonella enterica.
J.Biol.Chem., 276, 2001
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