5MZP
 
 | | Crystal structure of stabilized A2A adenosine receptor A2AR-StaR2-bRIL in complex with caffeine at 2.1A resolution | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, CAFFEINE, ... | | 著者 | Cheng, K.Y.R, Segala, E, Robertson, N, Deflorian, F, Dore, A.S, Errey, J.C, Fiez-Vandal, C, Marshall, F.H, Cooke, R.M. | | 登録日 | 2017-02-01 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures of Human A1 and A2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity.
Structure, 25, 2017
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7YKM
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2CCH
 | | The crystal structure of CDK2 cyclin A in complex with a substrate peptide derived from CDC modified with a gamma-linked ATP analogue | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CELL DIVISION CONTROL PROTEIN 6 HOMOLOG, CELL DIVISION PROTEIN KINASE 2, ... | | 著者 | Cheng, K.Y, Noble, M.E.M, Skamnaki, V, Brown, N.R, Lowe, E.D, Kontogiannis, L, Shen, K, Cole, P.A, Siligardi, G, Johnson, L.N. | | 登録日 | 2006-01-16 | | 公開日 | 2006-05-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Role of the Phospho-Cdk2/Cyclin a Recruitment Site in Substrate Recognition
J.Biol.Chem., 281, 2006
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2CCI
 | | Crystal structure of phospho-CDK2 Cyclin A in complex with a peptide containing both the substrate and recruitment sites of CDC6 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 6 homolog, Cyclin-A2, ... | | 著者 | Cheng, K.Y, Noble, M.E.M, Skamnaki, V, Brown, N.R, Lowe, E.D, Kontogiannis, L, Shen, K, Cole, P.A, Siligardi, G, Johnson, L.N. | | 登録日 | 2006-01-16 | | 公開日 | 2006-05-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition.
J. Biol. Chem., 281, 2006
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1Q4K
 | | The polo-box domain of Plk1 in complex with a phospho-peptide | | 分子名称: | Phospho-peptide sequence Met.Gln.Ser.pThr.Pro.Leu, Serine/threonine-protein kinase PLK | | 著者 | Cheng, K, Lowe, E.D, Sinclair, J, Nigg, E.A, Johnson, L.N. | | 登録日 | 2003-08-04 | | 公開日 | 2003-11-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex.
Embo J., 22, 2003
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3TE4
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6FWS
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6SER
 | | Crystal structure of human STARD10 | | 分子名称: | DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, START domain-containing protein 10, ... | | 著者 | Cheng, K, Wigley, D.B. | | 登録日 | 2019-07-30 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | | 主引用文献 | The crystal structure of human STARD10
To Be Published
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6SJF
 | | Cryo-EM structure of the RecBCD Chi unrecognised complex | | 分子名称: | Forked DNA substrate, RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ... | | 著者 | Cheng, K, Wilkinson, M, Wigley, D.B. | | 登録日 | 2019-08-13 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
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6SJG
 | | Cryo-EM structure of the RecBCD no Chi negative control complex | | 分子名称: | Forked DNA substrate, RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ... | | 著者 | Cheng, K, Wilkinson, M, Wigley, D.B. | | 登録日 | 2019-08-13 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
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6SJB
 | | Cryo-EM structure of the RecBCD Chi recognised complex | | 分子名称: | DNA fork substrate, RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ... | | 著者 | Cheng, K, Wilkinson, M, Wigley, D.B. | | 登録日 | 2019-08-13 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
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6SJE
 | | Cryo-EM structure of the RecBCD Chi partially-recognised complex | | 分子名称: | DNA fork substrate, RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ... | | 著者 | Cheng, K, Wilkinson, M, Wigley, D.B. | | 登録日 | 2019-08-13 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
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6T2U
 | | Cryo-EM structure of the RecBCD in complex with Chi-minus2 substrate | | 分子名称: | DNA (Chi-minus2), RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ... | | 著者 | Cheng, K, Wilkinson, M, Wigley, D.B. | | 登録日 | 2019-10-09 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
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6T2V
 | | Cryo-EM structure of the RecBCD in complex with Chi-plus2 substrate | | 分子名称: | DNA (Chi-plus2), RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ... | | 著者 | Cheng, K, Wilkinson, M, Wigley, D.B. | | 登録日 | 2019-10-09 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
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3V8I
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6FWR
 | | Structure of DinG in complex with ssDNA | | 分子名称: | ATP-dependent DNA helicase DinG, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), IRON/SULFUR CLUSTER | | 著者 | Cheng, K, Wigley, D.B. | | 登録日 | 2018-03-07 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | DNA translocation mechanism of an XPD family helicase.
Elife, 7, 2018
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1Q4O
 | | The structure of the polo box domain of human Plk1 | | 分子名称: | Serine/threonine-protein kinase PLK | | 著者 | Cheng, K.Y, Lowe, E.D, Sinclair, J, Nigg, E.A, Johnson, L.N. | | 登録日 | 2003-08-04 | | 公開日 | 2003-11-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex.
Embo J., 22, 2003
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6LRD
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8IOO
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8IU7
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7WRX
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7W8D
 | | The structure of Deinococcus radiodurans RuvC | | 分子名称: | Crossover junction endodeoxyribonuclease RuvC, MAGNESIUM ION | | 著者 | Cheng, K. | | 登録日 | 2021-12-07 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.75016141 Å) | | 主引用文献 | Biochemical and Structural Study of RuvC and YqgF from Deinococcus radiodurans.
Mbio, 13, 2022
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7W89
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7WRW
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5GI8
 | | Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-dopamine | | 分子名称: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, COENZYME A, Dopamine N-acetyltransferase, ... | | 著者 | Yang, Y.C, Lin, S.J, Cheng, K.C, Cheng, H.C, Lyu, P.C. | | 登録日 | 2016-06-22 | | 公開日 | 2017-07-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal Structure of Drosophila melanogaster Dopamine N-Acetyltransferase in Ternary Complex with CoA and Acetyl-dopamine
To Be Published
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