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PDB: 62 件

5K81
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Crystal Structure of a Primate APOBEC3G N-Terminal Domain
分子名称: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G,Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ...
著者Xiao, X, Li, S.-X, Yang, H, Chen, X.S.
登録日2016-05-27
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Crystal structures of APOBEC3G N-domain alone and its complex with DNA.
Nat Commun, 7, 2016
1SVM
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Co-crystal structure of SV40 large T antigen helicase domain and ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ZINC ION, ...
著者Gai, D, Zhao, R, Finkielstein, C.V, Chen, X.S.
登録日2004-03-29
公開日2004-10-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen.
Cell(Cambridge,Mass.), 119, 2004
5K82
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Crystal Structure of a Primate APOBEC3G N-Terminal Domain
分子名称: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G,Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ...
著者Xiao, X, Li, S.-X, Yang, H, Chen, X.S.
登録日2016-05-27
公開日2016-08-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.913 Å)
主引用文献Crystal structures of APOBEC3G N-domain alone and its complex with DNA.
Nat Commun, 7, 2016
3BGW
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The Structure Of A DnaB-Like Replicative Helicase And Its Interactions With Primase
分子名称: DNAB-Like Replicative Helicase
著者Wang, G, Klein, M.G, Tokonzaba, E, Zhang, Y, Holden, L.G, Chen, X.S.
登録日2007-11-27
公開日2007-12-25
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.91 Å)
主引用文献The structure of a DnaB-family replicative helicase and its interactions with primase.
Nat.Struct.Mol.Biol., 15, 2008
6P3X
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Crystal Structure of Full Length APOBEC3G E/Q (pH 7.0)
分子名称: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ZINC ION
著者Yang, H.J, Li, S.X, Chen, X.S.
登録日2019-05-25
公開日2020-02-12
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G.
Nat Commun, 11, 2020
6P3Z
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Crystal Structure of Full Length APOBEC3G E/Q (pH 5.2)
分子名称: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ZINC ION
著者Yang, H.J, Li, S.X, Chen, X.S.
登録日2019-05-25
公開日2020-02-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.844 Å)
主引用文献Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G.
Nat Commun, 11, 2020
6P3Y
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Crystal Structure of Full Length APOBEC3G E/Q (pH 7.4)
分子名称: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ZINC ION
著者Yang, H.J, Li, S.X, Chen, X.S.
登録日2019-05-25
公開日2020-02-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G.
Nat Commun, 11, 2020
6P40
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Crystal Structure of Full Length APOBEC3G FKL
分子名称: Apolipoprotein B mRNA editing enzyme, catalytic peptide-like 3G, ZINC ION
著者Yang, H.J, Li, S.X, Chen, X.S.
登録日2019-05-25
公開日2020-02-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.452 Å)
主引用文献Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G.
Nat Commun, 11, 2020
8E40
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Full-length APOBEC3G in complex with HIV-1 Vif, CBF-beta, and fork RNA
分子名称: Core-binding factor subunit beta, DNA dC->dU-editing enzyme APOBEC-3G, RNA, ...
著者Ito, F, Alvarez-Cabrera, A.L, Liu, S, Yang, H, Shiriaeva, A, Zhou, Z.H, Chen, X.S.
登録日2022-08-17
公開日2023-01-11
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.57 Å)
主引用文献Structural basis for HIV-1 antagonism of host APOBEC3G via Cullin E3 ligase.
Sci Adv, 9, 2023
8EDJ
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Crystal structure of rA3G-ssRNA-GA
分子名称: DNA dC->dU-editing enzyme APOBEC-3G, RNA (5'-R(P*UP*GP*AP*UP*UP*U)-3'), SULFATE ION, ...
著者Pacheco, J, Yang, H.J, Li, S.-X, Chen, X.S.
登録日2022-09-04
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural basis of sequence-specific RNA recognition by the antiviral factor APOBEC3G.
Nat Commun, 13, 2022
8FVJ
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Dimeric form of HIV-1 Vif in complex with human CBF-beta, ELOB, ELOC, and CUL5
分子名称: Core-binding factor subunit beta, Cullin-5, Elongin-B, ...
著者Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S.
登録日2023-01-19
公開日2023-09-06
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H.
Nat Commun, 14, 2023
8FY7
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SARS-CoV-2 main protease in complex with covalent inhibitor
分子名称: 3C-like proteinase nsp5, 4-methoxy-N-[(2S)-4-methyl-1-oxo-1-({(2S)-1-[(3S)-2-oxopyrrolidin-3-yl]but-3-en-2-yl}amino)pentan-2-yl]-1H-indole-2-carboxamide
著者Fried, W, Chen, X.S.
登録日2023-01-25
公開日2023-08-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Alkyne as a Latent Warhead to Covalently Target SARS-CoV-2 Main Protease.
J.Med.Chem., 66, 2023
8FY6
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SARS-CoV-2 main protease in complex with covalent inhibitor
分子名称: (1R,2S,5S)-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-N-{(2R)-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5
著者Fried, W, Chen, X.S.
登録日2023-01-25
公開日2023-08-30
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Alkyne as a Latent Warhead to Covalently Target SARS-CoV-2 Main Protease.
J.Med.Chem., 66, 2023
8FVI
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Human APOBEC3H bound to HIV-1 Vif in complex with CBF-beta, ELOB, ELOC, and CUL5
分子名称: Core-binding factor subunit beta, Cullin 5, DNA dC->dU-editing enzyme APOBEC-3H, ...
著者Ito, F, Alvarez-Cabrera, A.L, Zhou, Z.H, Chen, X.S.
登録日2023-01-19
公開日2023-09-06
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Structural basis of HIV-1 Vif-mediated E3 ligase targeting of host APOBEC3H.
Nat Commun, 14, 2023
5TKM
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Crystal structure of human APOBEC3B N-terminal Domain
分子名称: DNA dC->dU-editing enzyme APOBEC-3B, ZINC ION
著者Xiao, X, Yang, H, Arutiunian, V, Besse, G, Morimoto, C, Zirkle, B, Chen, X.S.
登録日2016-10-07
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation.
Nucleic Acids Res., 45, 2017
5W45
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Crystal structure of APOBEC3H
分子名称: APOBEC3H, ZINC ION
著者Ito, F, Yang, H.J, Xiao, X, Li, S.X, Wolfe, A, Zirkle, B, Arutiunian, V, Chen, X.S.
登録日2017-06-09
公開日2018-03-14
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.486 Å)
主引用文献Understanding the Structure, Multimerization, Subcellular Localization and mC Selectivity of a Genomic Mutator and Anti-HIV Factor APOBEC3H.
Sci Rep, 8, 2018
5W2M
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APOBEC3F Catalytic Domain Complex with a Single-Stranded DNA
分子名称: DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3F, ZINC ION
著者Fang, Y, Xiao, X, Li, S.-X, Wolfe, A, Chen, X.S.
登録日2017-06-06
公開日2017-12-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Molecular Interactions of a DNA Modifying Enzyme APOBEC3F Catalytic Domain with a Single-Stranded DNA.
J. Mol. Biol., 430, 2018
5W1O
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Crystal Structure of HPV16 L1 Pentamer Bound to Heparin Oligosaccharides
分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose, 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose, Major capsid protein L1
著者Dasgupta, J, Chen, X.S.
登録日2017-06-04
公開日2017-10-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of oligosaccharide receptor recognition by human papillomavirus.
J. Biol. Chem., 286, 2011
4ME3
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1.8 Angstrom Crystal Structure of the N-terminal Domain of an Archaeal MCM
分子名称: DNA replication licensing factor MCM related protein, ZINC ION
著者Fu, Y, Slaymaker, I.M, Wang, G, Chen, X.S.
登録日2013-08-24
公開日2014-01-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.794 Å)
主引用文献The 1.8- angstrom Crystal Structure of the N-Terminal Domain of an Archaeal MCM as a Right-Handed Filament.
J.Mol.Biol., 426, 2014
4IGP
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Histone H3 Lysine 4 Demethylating Rice JMJ703 apo enzyme
分子名称: FE (III) ION, Os05g0196500 protein
著者Chen, Q.F, Chen, X.S, Wang, Q, Zhang, F.B, Lou, Z.Y, Zhang, Q.F, Zhou, D.X.
登録日2012-12-17
公開日2013-04-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice.
PLoS Genet., 9, 2013
4IGQ
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Histone H3 Lysine 4 Demethylating Rice JMJ703 in complex with methylated H3K4 substrate
分子名称: FE (III) ION, N-OXALYLGLYCINE, Os05g0196500 protein, ...
著者Chen, Q.F, Chen, X.S, Wang, Q, Zhang, F.B, Lou, Z.Y, Zhang, Q.F, Zhou, D.X.
登録日2012-12-17
公開日2013-04-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice.
PLoS Genet., 9, 2013
4IGO
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Histone H3 Lysine 4 Demethylating rice Rice JMJ703 in complex with alpha-KG
分子名称: 2-OXOGLUTARIC ACID, FE (III) ION, Os05g0196500 protein
著者Chen, Q.F, Chen, X.S, Wang, Q, Zhang, F.B, Lou, Z.Y, Zhang, Q.F, Zhou, D.X.
登録日2012-12-17
公開日2013-04-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice.
PLoS Genet., 9, 2013
3E1U
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The Crystal Structure of the Anti-Viral APOBEC3G Catalytic Domain
分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
著者Holden, L, Prochnow, C, Chang, Y.P, Bransteitter, R, Chelico, L, Sen, U, Stevens, R.C, Goodman, R.F, Chen, X.S.
登録日2008-08-04
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Nature, 456, 2008
3IQS
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Crystal structure of the anti-viral APOBEC3G catalytic domain
分子名称: DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION
著者Holden, L.G, Prochnow, C, Chang, Y.P, Bransteitter, R, Chelico, L, Sen, U, Stevens, R.C, Goodman, R.F, Chen, X.S.
登録日2009-08-20
公開日2009-11-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the anti-viral APOBEC3G catalytic domain and functional implications.
Nature, 456, 2008
2H1L
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The Structure of the Oncoprotein SV40 Large T Antigen and p53 Tumor Suppressor Complex
分子名称: Cellular tumor antigen p53, Large T antigen, ZINC ION
著者Lilyestrom, W, Klein, M.G, Chen, X.S.
登録日2006-05-16
公開日2006-09-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor.
Genes Dev., 20, 2006

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