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PDB: 281 results

5T0G
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Structural basis for dynamic regulation of the human 26S proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5T0H
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Structural basis for dynamic regulation of the human 26S proteasome
Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ...
Authors:Chen, S, Wu, J, Lu, Y, Ma, Y.B, Lee, B.H, Yu, Z, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
Deposit date:2016-08-16
Release date:2016-10-19
Last modified:2016-11-30
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Structural basis for dynamic regulation of the human 26S proteasome.
Proc.Natl.Acad.Sci.USA, 113, 2016
5VOU
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Structure of AMPA receptor-TARP complex
Descriptor: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Chen, S, Zhao, Y, Wang, Y.S, Shekhar, M, Tajkhorshid, E, Gouaux, E.
Deposit date:2017-05-03
Release date:2017-07-12
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
1F5T
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DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL AND DTXR CONSENSUS BINDING SEQUENCE
Descriptor: 43MER DNA CONTAINING DXTR CONSENSUS BINDING SEQUENCE, DIPHTHERIA TOXIN REPRESSOR, NICKEL (II) ION
Authors:Chen, S, White, A, Love, J, Murphy, J.R, Ringe, D.
Deposit date:2000-06-15
Release date:2000-09-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Methyl groups of thymine bases are important for nucleic acid recognition by DtxR.
Biochemistry, 39, 2000
7F5F
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SARS-CoV-2 ORF8 S84
Descriptor: CALCIUM ION, ORF8 protein
Authors:Chen, S, Zhou, Z, Chen, X.
Deposit date:2021-06-22
Release date:2022-01-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal Structures of Bat and Human Coronavirus ORF8 Protein Ig-Like Domain Provide Insights Into the Diversity of Immune Responses.
Front Immunol, 12, 2021
1S3M
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Structural and Functional Characterization of a Novel Archaeal Phosphodiesterase
Descriptor: Hypothetical protein MJ0936, NICKEL (II) ION
Authors:Chen, S, Busso, D, Yakunin, A.F, Kuznetsova, E, Proudfoot, M, Jancrick, J, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-01-13
Release date:2004-08-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii
J.Biol.Chem., 279, 2004
1S3N
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Structural and Functional Characterization of a Novel Archaeal Phosphodiesterase
Descriptor: Hypothetical protein MJ0936, MANGANESE (II) ION
Authors:Chen, S, Busso, D, Yakunin, A.F, Kuznetsova, E, Proudfoot, M, Jancrick, J, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-01-13
Release date:2004-08-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii
J.Biol.Chem., 279, 2004
1S3L
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Structural and Functional Characterization of a Novel Archaeal Phosphodiesterase
Descriptor: Hypothetical protein MJ0936, PHOSPHATE ION, UNKNOWN ATOM OR ION
Authors:Chen, S, Busso, D, Yakunin, A.F, Kuznetsova, E, Proudfoot, M, Jancrick, J, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-01-13
Release date:2004-08-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii
J.Biol.Chem., 279, 2004
1SBQ
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Crystal Structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae at 2.2 resolution
Descriptor: 5,10-Methenyltetrahydrofolate synthetase homolog, SULFATE ION
Authors:Chen, S, Shin, D.H, Pufan, R, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-02-10
Release date:2004-08-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae (GI: 13508087) at 2.2 A resolution
Proteins, 56, 2004
1N0F
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CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF
Descriptor: Protein mraZ
Authors:Chen, S, Jancrick, J, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2002-10-13
Release date:2003-10-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif.
Proteins, 55, 2004
1N0G
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Crystal Structure of A Cell Division and Cell Wall Biosynthesis Protein UPF0040 from Mycoplasma pneumoniae: Indication of A Novel Fold with A Possible New Conserved Sequence Motif
Descriptor: Protein mraZ
Authors:Chen, S, Jancarik, J, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2002-10-13
Release date:2003-10-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif.
Proteins, 55, 2004
1N0E
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CRYSTAL STRUCTURE OF A CELL DIVISION AND CELL WALL BIOSYNTHESIS PROTEIN UPF0040 FROM MYCOPLASMA PNEUMONIAE: INDICATION OF A NOVEL FOLD WITH A POSSIBLE NEW CONSERVED SEQUENCE MOTIF
Descriptor: Protein mraZ
Authors:Chen, S, Jancrick, J, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2002-10-13
Release date:2003-10-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif.
Proteins, 55, 2004
6M3M
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BU of 6m3m by Molmil
Crystal structure of SARS-CoV-2 nucleocapsid protein N-terminal RNA binding domain
Descriptor: Nucleoprotein
Authors:Chen, S, Kang, S.
Deposit date:2020-03-04
Release date:2020-03-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites.
Acta Pharm Sin B, 10, 2020
1U3F
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Structural and Functional Characterization of a 5,10-Methenyltetrahydrofolate Synthetase from Mycoplasma pneumoniae (GI: 13508087)
Descriptor: 5,10-Methenyltetrahydrofolate Synthetase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Chen, S, Yakunin, A.F, Proudfoot, M, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-07-21
Release date:2004-12-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae (GI: 13508087) at 2.2 A resolution
Proteins, 56, 2004
1U3G
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Structural and Functional Characterization of a 5,10-Methenyltetrahydrofolate Synthetase from Mycoplasma pneumoniae (GI: 13508087)
Descriptor: 5,10-Methenyltetrahydrofolate Synthetase, 5-HYDROXYMETHYLENE-6-HYDROFOLIC ACID, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Chen, S, Yakunin, A.F, Proudfoot, M, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
Deposit date:2004-07-21
Release date:2004-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae (GI: 13508087) at 2.2 A resolution
Proteins, 56, 2004
7CR5
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BU of 7cr5 by Molmil
Complex structure of a human monoclonal antibody with SARS-CoV-2 nucleocapsid protein NTD
Descriptor: Nucleoprotein, ZINC ION, monoclonal antibody chain H, ...
Authors:Chen, S, Kang, S.
Deposit date:2020-08-12
Release date:2021-03-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:A SARS-CoV-2 antibody curbs viral nucleocapsid protein-induced complement hyperactivation.
Nat Commun, 12, 2021
5DAH
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BU of 5dah by Molmil
Crystal structure of PZP domain of human AF10 protein fused with Histone H3 peptide
Descriptor: Histone H3 peptide, Protein AF-10, SULFATE ION, ...
Authors:Chen, S, Patel, D.J.
Deposit date:2015-08-19
Release date:2015-10-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.611 Å)
Cite:The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol.Cell, 60, 2015
4JBW
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Crystal structure of E. coli maltose transporter MalFGK2 in complex with its regulatory protein EIIAglc
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, Glucose-specific phosphotransferase enzyme IIA component, Maltose transport system permease protein MalF, ...
Authors:Chen, S, Oldham, M.L, Davidson, A.L, Chen, J.
Deposit date:2013-02-20
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.913 Å)
Cite:Carbon catabolite repression of the maltose transporter revealed by X-ray crystallography.
Nature, 499, 2013
7DE1
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BU of 7de1 by Molmil
Crystal structure of SARS-CoV-2 nucleocapsid protein C-terminal RNA binding domain
Descriptor: DI(HYDROXYETHYL)ETHER, Nucleoprotein
Authors:Chen, S, Kang, S.
Deposit date:2020-11-01
Release date:2021-01-27
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insight Into the SARS-CoV-2 Nucleocapsid Protein C-Terminal Domain Reveals a Novel Recognition Mechanism for Viral Transcriptional Regulatory Sequences.
Front Chem, 8, 2020
4JLW
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Crystal structure of formaldehyde dehydrogenase from Pseudomonas aeruginosa
Descriptor: Glutathione-independent formaldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
Authors:Chen, S, Liao, Y.P, Wang, D.L, Wang, S, Ding, J.F, Wang, Y.M, Cai, L.J, Ran, X.Y, Zhu, H.X.
Deposit date:2013-03-13
Release date:2013-10-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of formaldehyde dehydrogenase from Pseudomonas aeruginosa: the binary complex with the cofactor NAD+.
Acta Crystallogr.,Sect.F, 69, 2013
5DAG
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BU of 5dag by Molmil
Crystal structure of PZP domain of human AF10 protein
Descriptor: Protein AF-10, ZINC ION
Authors:Chen, S, Patel, D.J.
Deposit date:2015-08-19
Release date:2015-10-21
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Mol.Cell, 60, 2015
8K1V
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Human TWIK-related acid-sensitive potassium channel TASK3 at pH 7.4, 5 mM KCl and 135 mM NaCl
Descriptor: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9
Authors:Chen, S, Lin, H.
Deposit date:2023-07-11
Release date:2024-04-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
8K1Q
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Human TWIK-related acid-sensitive potassium channel TASK3 at pH 6.0, 5 mM KCl and 135 mM NaCl
Descriptor: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9
Authors:Chen, S, Lin, H.
Deposit date:2023-07-11
Release date:2024-04-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
8K1Z
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Human TWIK-related acid-sensitive potassium channel TASK3 at pH 6.0, 200 mM KCl
Descriptor: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9
Authors:Chen, S, Lin, H.
Deposit date:2023-07-11
Release date:2024-04-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
8K1J
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BU of 8k1j by Molmil
Human TWIK-related acid-sensitive potassium channel TASK3 at pH 7.4,200 mM KCl
Descriptor: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9
Authors:Chen, S, Lin, H.
Deposit date:2023-07-11
Release date:2024-04-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024

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數據於2024-05-29公開中

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