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PDB: 27 results

1GHM
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Structures of the acyl-enzyme complex of the staphylococcus aureus beta-lactamase mutant GLU166ASP:ASN170GLN with degraded cephaloridine
Descriptor: 5-METHYL-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, BETA-LACTAMASE, CARBONATE ION, ...
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:2000-12-19
Release date:2001-04-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Structures of the acyl-enzyme complexes of the Staphylococcus aureus beta-lactamase mutant Glu166Asp:Asn170Gln with benzylpenicillin and cephaloridine.
Biochemistry, 40, 2001
1GHP
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STRUCTURES OF THE ACYL-ENZYME COMPLEX OF THE STAPHYLOCOCCUS AUREUS BETA-LACTAMASE MUTANT GLU166ASP:ASN170GLN WITH DEGRADED BENZYLPENICILLIN
Descriptor: BETA-LACTAMASE, OPEN FORM - PENICILLIN G, SULFATE ION
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:2000-12-21
Release date:2001-04-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structures of the acyl-enzyme complexes of the Staphylococcus aureus beta-lactamase mutant Glu166Asp:Asn170Gln with benzylpenicillin and cephaloridine.
Biochemistry, 40, 2001
1GHI
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STRUCTURE OF BETA-LACTAMASE GLU166ASP:ASN170GLN MUTANT
Descriptor: BETA-LACTAMASE, CARBONATE ION
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:2000-12-18
Release date:2001-04-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of the acyl-enzyme complexes of the Staphylococcus aureus beta-lactamase mutant Glu166Asp:Asn170Gln with benzylpenicillin and cephaloridine.
Biochemistry, 40, 2001
1KGF
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STRUCTURE OF BETA-LACTAMASE ASN 170 GLN MUTANT
Descriptor: BETA-LACTAMASE
Authors:Chen, C.C.H, Zawadzke, L.E, Herzberg, O.
Deposit date:1996-10-17
Release date:1997-03-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Elimination of the hydrolytic water molecule in a class A beta-lactamase mutant: crystal structure and kinetics.
Biochemistry, 35, 1996
1KGE
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STRUCTURE OF BETA-LACTAMASE ASN 170 MET MUTANT
Descriptor: BETA-LACTAMASE
Authors:Chen, C.C.H, Zawadzke, L.E, Herzberg, O.
Deposit date:1996-10-17
Release date:1997-04-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Elimination of the hydrolytic water molecule in a class A beta-lactamase mutant: crystal structure and kinetics.
Biochemistry, 35, 1996
1KGG
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STRUCTURE OF BETA-LACTAMASE GLU166GLN:ASN170ASP MUTANT
Descriptor: PROTEIN (BETA-LACTAMASE), SULFATE ION
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:1999-05-20
Release date:1999-05-28
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Relocation of the catalytic carboxylate group in class A beta-lactamase: the structure and function of the mutant enzyme Glu166-->Gln:Asn170-->Asp.
Protein Eng., 12, 1999
1BLC
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INHIBITION OF BETA-LACTAMASE BY CLAVULANATE: TRAPPED INTERMEDIATES IN CRYOCRYSTALLOGRAPHIC STUDIES
Descriptor: BETA-LACTAMASE, N-(1-CARBOXY-2-HYDROXY-4-OXO-BUTYL)-N-(3-OXO-CISPROPENYL)AMINE, N-(2-HYDROXY-4-OXO-BUTYL)-N-(3-OXO-TRANSPROPENYL)AMINE, ...
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:1993-09-27
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Inhibition of beta-lactamase by clavulanate. Trapped intermediates in cryocrystallographic studies.
J.Mol.Biol., 224, 1992
1BLH
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BU of 1blh by Molmil
STRUCTURE OF A PHOSPHONATE-INHIBITED BETA-LACTAMASE. AN ANALOG OF THE TETRAHEDRAL TRANSITION STATE(SLASH)INTERMEDIATE OF BETA-LACTAM HYDROLYSIS
Descriptor: BETA-LACTAMASE, [[N-(BENZYLOXYCARBONYL)AMINO]METHYL]PHOSPHATE
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:1993-09-30
Release date:1994-08-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a phosphonate-inhibited beta-lactamase. An analog of the tetrahedral transition state/intermediate of beta-lactam hydrolysis.
J.Mol.Biol., 234, 1993
1DJC
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STRUCTURE OF BETA-LACTAMASE PRECURSOR, S70A MUTANT, AT 120K
Descriptor: BETA-LACTAMASE, SULFATE ION
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:1996-08-13
Release date:1997-03-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and kinetics of the beta-lactamase mutants S70A and K73H from Staphylococcus aureus PC1.
Biochemistry, 35, 1996
1DJB
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STRUCTURE OF BETA-LACTAMASE PRECURSOR, S70A MUTANT, AT 298K
Descriptor: BETA-LACTAMASE
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:1996-08-13
Release date:1997-03-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and kinetics of the beta-lactamase mutants S70A and K73H from Staphylococcus aureus PC1.
Biochemistry, 35, 1996
1DJA
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STRUCTURE OF BETA-LACTAMASE PRECURSOR, K73H MUTANT, AT 298K
Descriptor: BETA-LACTAMASE
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:1996-08-13
Release date:1997-03-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and kinetics of the beta-lactamase mutants S70A and K73H from Staphylococcus aureus PC1.
Biochemistry, 35, 1996
1JOE
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BU of 1joe by Molmil
Crystal Structure of Autoinducer-2 Production Protein (LuxS) from Heamophilus influenzae
Descriptor: AUTOINDUCER-2 PRODUCTION PROTEIN, MERCURY (II) ION, ZINC ION
Authors:Chen, C.C.H, Parsons, J.F, Lim, K, Lehmann, C, Tempczyk, A, Eisenstein, E, Herzberg, O, Structure 2 Function Project (S2F)
Deposit date:2001-07-27
Release date:2001-08-08
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:CRYSTAL STRUCTURE OF AUTOINDUCER-2 PRODUCTION PROTEIN (LUXS) FROM HEAMOPHILUS INFLUENZAE--A CASE OF TWINNED CRYSTAL
To be Published
1M32
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BU of 1m32 by Molmil
Crystal Structure of 2-aminoethylphosphonate Transaminase
Descriptor: 2-aminoethylphosphonate-pyruvate aminotransferase, PHOSPHATE ION, PHOSPHONOACETALDEHYDE, ...
Authors:Chen, C.C.H, Zhang, H, Kim, A.D, Howard, A, Sheldrick, G.M, Mariano-Dunnaway, D, Herzberg, O.
Deposit date:2002-06-26
Release date:2002-11-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Degradation Pathway of the Phosphonate Ciliatine: Crystal Structure of 2-Aminoethylphosphonate Transaminase
Biochemistry, 41, 2002
3NV7
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BU of 3nv7 by Molmil
Crystal structure of H.pylori phosphopantetheine adenylyltransferase mutant I4V/N76Y
Descriptor: ACETIC ACID, Phosphopantetheine adenylyltransferase, SULFATE ION
Authors:Chen, C.H, Cheng, C.S, Yin, H.S.
Deposit date:2010-07-08
Release date:2011-07-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of H.pylori phosphopantetheine adenylyltransferase mutant I4V/N76Y
To be Published
2GVU
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BU of 2gvu by Molmil
Crystal structure of diisopropyl fluorophosphatase (DFPase), mutant D229N / N120D
Descriptor: CALCIUM ION, Phosphotriesterase
Authors:Chen, J.C.H, Blum, M.M.
Deposit date:2006-05-03
Release date:2006-09-19
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of a designed substrate analogue to diisopropyl fluorophosphatase: implications for the phosphotriesterase mechanism.
J.Am.Chem.Soc., 128, 2006
2GVV
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BU of 2gvv by Molmil
Structure of diisopropyl fluorophosphatase (DFPase) in complex with dicyclopentylphosphoroamidate (DcPPA)
Descriptor: CALCIUM ION, DICYCLOPENTYL PHOSPHORAMIDATE, Phosphotriesterase
Authors:Chen, J.C.H, Blum, M.M.
Deposit date:2006-05-03
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Binding of a designed substrate analogue to diisopropyl fluorophosphatase: implications for the phosphotriesterase mechanism.
J.Am.Chem.Soc., 128, 2006
2GVW
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BU of 2gvw by Molmil
Structure of diisopropyl fluorophosphatase (DFPase) holoenzyme (RT)
Descriptor: CALCIUM ION, Phosphotriesterase
Authors:Chen, J.C.H, Blum, M.M.
Deposit date:2006-05-03
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Binding of a designed substrate analogue to diisopropyl fluorophosphatase: implications for the phosphotriesterase mechanism.
J.Am.Chem.Soc., 128, 2006
2HRW
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BU of 2hrw by Molmil
Crystal Structure of Phosphonopyruvate Hydrolase
Descriptor: CHLORIDE ION, Phosphonopyruvate hydrolase, SODIUM ION
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:2006-07-20
Release date:2006-10-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and Kinetics of Phosphonopyruvate Hydrolase from Voriovorax sp. Pal2: New Insight into the Divergence of Catalysis within the PEP Mutase/Isocitrate Lyase Superfamily
Biochemistry, 45, 2006
2HJP
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BU of 2hjp by Molmil
Crystal Structure of Phosphonopyruvate Hydrolase Complex with Phosphonopyruvate and Mg++
Descriptor: CHLORIDE ION, MAGNESIUM ION, PHOSPHONOPYRUVATE, ...
Authors:Chen, C.C.H, Herzberg, O.
Deposit date:2006-06-30
Release date:2006-10-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and Kinetics of Phosphonopyruvate Hydrolase from Voriovorax sp. Pal2: New Insight into the Divergence of Catalysis within the PEP Mutase/Isocitrate Lyase Superfamily
Biochemistry, 45, 2006
2LA1
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BU of 2la1 by Molmil
Expression in Pichia pastoris and backbone dynamics of dendroaspin, a three finger toxin
Descriptor: Mambin
Authors:Chuang, W.J, Cheng, C.H, Chen, Y.C, Shiu, J.H.
Deposit date:2011-03-01
Release date:2012-03-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Dynamics and functional differences between dendroaspin and rhodostomin: Insights into protein scaffolds in integrin recognition
Protein Sci., 21, 2012
4AUA
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BU of 4aua by Molmil
Liganded X-ray crystal structure of cyclin dependent kinase 6 (CDK6)
Descriptor: 1H-benzimidazol-2-yl(1H-pyrrol-2-yl)methanone, CYCLIN-DEPENDENT KINASE 6
Authors:Cho, Y.S, Angove, H, Brain, C, Chen, C.H.T, Cheng, R, Chopra, R, Chung, K, Congreve, M, Dagostin, C, Davis, D, Feltell, R, Giraldes, J, Hiscock, S, Kim, S, Kovats, S, Lagu, B, Lewry, K, Loo, A, Lu, Y, Luzzio, M, Maniara, W, Mcmenamin, R, Mortenson, P, Benning, R, O'Reilly, M, Rees, D, Shen, J, Smith, T, Wang, Y, Williams, G, Woolford, A, Wrona, W, Xu, M, Yang, F, Howard, S.
Deposit date:2012-05-15
Release date:2013-02-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 Inhibitors.
ACS Med Chem Lett, 3, 2012
1DIK
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BU of 1dik by Molmil
PYRUVATE PHOSPHATE DIKINASE
Descriptor: PYRUVATE PHOSPHATE DIKINASE, SULFATE ION
Authors:Herzberg, O, Chen, C.C.H.
Deposit date:1995-12-06
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Swiveling-domain mechanism for enzymatic phosphotransfer between remote reaction sites.
Proc.Natl.Acad.Sci.USA, 93, 1996
5VG1
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BU of 5vg1 by Molmil
Neutron crystallographic structure of a Jonesia denitrificans lytic polysaccharide monooxygenase
Descriptor: COPPER (II) ION, Chitinase, PEROXIDE ION
Authors:Bacik, J.-P, Unkefer, C.J, Chen, J.C.H.
Deposit date:2017-04-10
Release date:2017-05-24
Last modified:2023-10-04
Method:NEUTRON DIFFRACTION (2.1 Å)
Cite:Neutron and Atomic Resolution X-ray Structures of a Lytic Polysaccharide Monooxygenase Reveal Copper-Mediated Dioxygen Binding and Evidence for N-Terminal Deprotonation.
Biochemistry, 56, 2017
5VG0
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BU of 5vg0 by Molmil
Room temperature X-ray crystallographic structure of a Jonesia denitrificans lytic polysaccharide monooxygenase at 1.1 angstrom resolution.
Descriptor: COPPER (II) ION, Chitinase, PEROXIDE ION
Authors:Bacik, J.-P, Unkefer, C.J, Chen, J.C.H.
Deposit date:2017-04-10
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Neutron and Atomic Resolution X-ray Structures of a Lytic Polysaccharide Monooxygenase Reveal Copper-Mediated Dioxygen Binding and Evidence for N-Terminal Deprotonation.
Biochemistry, 56, 2017
6KYC
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BU of 6kyc by Molmil
Structure of the S207A mutant of Clostridium difficile sortase B
Descriptor: Putative peptidase C60B, sortase B
Authors:Kang, C.Y, Huang, I.H, Wu, T.Y, Chang, J.C, Hsiao, Y.Y, Cheng, C.H, Tsai, W.J, Hsu, K.C, Wang, S.Y.
Deposit date:2019-09-17
Release date:2020-02-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:Functional analysis ofClostridium difficilesortase B reveals key residues for catalytic activity and substrate specificity.
J.Biol.Chem., 295, 2020

 

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