1GHP

STRUCTURES OF THE ACYL-ENZYME COMPLEX OF THE STAPHYLOCOCCUS AUREUS BETA-LACTAMASE MUTANT GLU166ASP:ASN170GLN WITH DEGRADED BENZYLPENICILLIN

Summary for 1GHP

Entry DOI	10.2210/pdb1ghp/pdb
Descriptor	BETA-LACTAMASE, SULFATE ION, OPEN FORM - PENICILLIN G, ... (4 entities in total)
Functional Keywords	hydrolase, antibiotic resistance, beta-lactam hydrolysis, benzylpenicillin, cephaloridine
Biological source	Staphylococcus aureus
Total number of polymer chains	1
Total formula weight	29695.07
Authors	Chen, C.C.H.,Herzberg, O. (deposition date: 2000-12-21, release date: 2001-04-04, Last modification date: 2023-08-09)
Primary citation	Chen, C.C.,Herzberg, O. Structures of the acyl-enzyme complexes of the Staphylococcus aureus beta-lactamase mutant Glu166Asp:Asn170Gln with benzylpenicillin and cephaloridine. Biochemistry, 40:2351-2358, 2001 Cited by PubMed: 11327855 DOI: 10.1021/bi002277h PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.76 Å)

Structure validation