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PDB: 102 件

1N87
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Solution structure of the U-box of Prp19
分子名称: Pre-mRNA splicing factor PRP19
著者Chazin, W.J, Ohi, M.D, Vander Kooi, C.W.
登録日2002-11-19
公開日2003-04-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural insights into the U-box, a domain associated with multi-ubiquitination
Nat.Struct.Biol., 10, 2003
3CJJ
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Crystal structure of human rage ligand-binding domain
分子名称: ACETATE ION, Advanced glycosylation end product-specific receptor, ZINC ION
著者Koch, M, Dattilo, B.M, Schiefner, A, Diez, J, Chazin, W.J, Fritz, G.
登録日2008-03-13
公開日2009-03-24
最終更新日2011-12-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural basis for ligand recognition and activation of RAGE.
Structure, 18, 2010
6DTZ
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BU of 6dtz by Molmil
Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain, Y397F mutant
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, ...
著者Salay, L.E, Chazin, W.J.
登録日2018-06-18
公開日2018-12-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Yeast require redox switching in DNA primase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1HV2
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BU of 1hv2 by Molmil
SOLUTION STRUCTURE OF YEAST ELONGIN C IN COMPLEX WITH A VON HIPPEL-LINDAU PEPTIDE
分子名称: ELONGIN C, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR
著者Botuyan, M.V, Mer, G, Yi, G.-S, Koth, C.M, Case, D.A, Edwards, A.M, Chazin, W.J, Arrowsmith, C.H.
登録日2001-01-05
公開日2001-09-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of yeast elongin C in complex with a von Hippel-Lindau peptide.
J.Mol.Biol., 312, 2001
5I7M
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BU of 5i7m by Molmil
Crystal structure of Y345F mutant of human primase p58 iron-sulfur cluster domain
分子名称: DNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION
著者Salay, L.E, Thompson, M.K, Chazin, W.J.
登録日2016-02-17
公開日2017-03-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.
Science, 355, 2017
7TL3
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Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 5YF431
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
著者Blee, A.M, Salay, L.E, Chazin, W.J.
登録日2022-01-18
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.066 Å)
主引用文献Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
7TL4
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Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 6YF
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, IRON/SULFUR CLUSTER
著者Blee, A.M, Salay, L.E, Chazin, W.J.
登録日2022-01-18
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.805 Å)
主引用文献Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
7TL2
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Crystal Structure of Yeast p58C Multi-Tyrosine Mutant 5YF412
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, GLYCEROL, ...
著者Blee, A.M, Salay, L.E, Chazin, W.J.
登録日2022-01-18
公開日2022-06-29
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.529 Å)
主引用文献Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.
Biochemistry, 61, 2022
5DQO
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Crystal structure of Y347F mutant of human primase p58 iron-sulfur cluster domain
分子名称: DNA primase large subunit, IRON/SULFUR CLUSTER
著者Salay, L.E, Thompson, M.K, Chazin, W.J.
登録日2015-09-15
公開日2016-09-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.
Science, 355, 2017
2CNP
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BU of 2cnp by Molmil
HIGH RESOLUTION SOLUTION STRUCTURE OF APO RABBIT CALCYCLIN, NMR, 22 STRUCTURES
分子名称: CALCYCLIN
著者Maler, L, Potts, B.C.M, Chazin, W.J.
登録日1999-01-07
公開日1999-07-22
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献High resolution solution structure of apo calcyclin and structural variations in the S100 family of calcium-binding proteins.
J.Biomol.NMR, 13, 1999
2BCB
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BU of 2bcb by Molmil
HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K
分子名称: CALBINDIN D9K
著者Kordel, J, Skelton, N.J, Akke, M, Chazin, W.J.
登録日1993-08-18
公開日1993-10-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献High-resolution structure of calcium-loaded calbindin D9k.
J.Mol.Biol., 231, 1993
2BCA
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BU of 2bca by Molmil
HIGH-RESOLUTION SOLUTION STRUCTURE OF CALCIUM-LOADED CALBINDIN D9K
分子名称: CALBINDIN D9K
著者Kordel, J, Skelton, N.J, Akke, M, Chazin, W.J.
登録日1993-08-18
公開日1993-10-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献High-resolution structure of calcium-loaded calbindin D9k.
J.Mol.Biol., 231, 1993
1Z1D
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BU of 1z1d by Molmil
Structural Model for the interaction between RPA32 C-terminal domain and SV40 T antigen origin binding domain.
分子名称: Large T antigen, Replication protein A 32 kDa subunit
著者Arunkumar, A.I, Klimovich, V, Jiang, X, Ott, R.D, Mizoue, L, Fanning, E, Chazin, W.J.
登録日2005-03-03
公開日2005-05-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Insights into hRPA32 C-terminal domain--mediated assembly of the simian virus 40 replisome.
Nat.Struct.Mol.Biol., 12, 2005
5DBR
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BU of 5dbr by Molmil
Ca2+ CaM with human cardiac Na+ channel (NaV1.5) inactivation gate
分子名称: CALCIUM ION, Calmodulin, Sodium channel protein type 5 subunit alpha
著者Johnson, C.N, Thompson, M.K, Chazin, W.J.
登録日2015-08-21
公開日2017-02-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Enhanced Understanding of Ca2+ Modulation of the Human Cardiac Sodium Channel: Tight Binding of Calmodulin to the Inactivation Gate
To Be Published
5E7N
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BU of 5e7n by Molmil
Crystal Structure of RPA70N in complex with VU0085636
分子名称: 2-({3-[(4-bromophenyl)sulfamoyl]-4-methylbenzoyl}amino)benzoic acid, Replication protein A 70 kDa DNA-binding subunit
著者Gilston, B.A, Patrone, J.D, Pelz, N.F, Bates, B.S, Souza-Fagundes, E.M, Vangamudi, B, Camper, D, Kuznetsov, A, Browning, C.F, Feldkamp, M.D, Olejniczak, E.T, Rossanese, O.W, Waterson, A.G, Fesik, S.W, Chazin, W.J.
登録日2015-10-12
公開日2016-01-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Identification and Optimization of Anthranilic Acid Based Inhibitors of Replication Protein A.
Chemmedchem, 11, 2016
3LRV
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BU of 3lrv by Molmil
The Prp19 WD40 Domain Contains a Conserved Protein Interaction Region Essential for its Function.
分子名称: Pre-mRNA-splicing factor 19, SULFATE ION
著者Vander Kooi, C.W, Chazin, W.J.
登録日2010-02-11
公開日2010-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Prp19 WD40 domain contains a conserved protein interaction region essential for its function.
Structure, 18, 2010
3L9Q
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Crystal structure of human polymerase alpha-primase p58 iron-sulfur cluster domain
分子名称: DNA primase large subunit, IRON/SULFUR CLUSTER, SULFATE ION
著者Vaithiyalingam, S, Eichman, B.F, Chazin, W.J.
登録日2010-01-05
公開日2010-07-14
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Insights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase.
Proc.Natl.Acad.Sci.USA, 107, 2010
9PCY
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BU of 9pcy by Molmil
HIGH-RESOLUTION SOLUTION STRUCTURE OF REDUCED FRENCH BEAN PLASTOCYANIN AND COMPARISON WITH THE CRYSTAL STRUCTURE OF POPLAR PLASTOCYANIN
分子名称: COPPER (II) ION, PLASTOCYANIN
著者Moore, J.M, Lepre, C.A, Gippert, G.P, Chazin, W.J, Case, D.A, Wright, P.E.
登録日1991-03-18
公開日1993-10-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献High-resolution solution structure of reduced French bean plastocyanin and comparison with the crystal structure of poplar plastocyanin.
J.Mol.Biol., 221, 1991
1RL1
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Solution structure of human Sgt1 CS domain
分子名称: Suppressor of G2 allele of SKP1 homolog
著者Lee, Y.-T, Jacob, J, Michowski, W, Nowotny, M, Kuznicki, J, Chazin, W.J.
登録日2003-11-24
公開日2004-05-04
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Human Sgt1 Binds HSP90 through the CHORD-Sgt1 Domain and Not the Tetratricopeptide Repeat Domain
J.Biol.Chem., 279, 2004
8UCU
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BU of 8ucu by Molmil
Partial DNA termination subcomplex of Xenopus laevis DNA polymerase alpha-primase
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ...
著者Mullins, E.A, Chazin, W.J, Eichman, B.F.
登録日2023-09-27
公開日2023-10-11
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase.
Nat.Struct.Mol.Biol., 31, 2024
6XQ6
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Receptor for Advanced Glycation End Products VC1 domain in complex with Fragment 11
分子名称: 3-phenoxyphenol, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
著者Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
登録日2020-07-09
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ3
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Receptor for Advanced Glycation End Products VC1 domain in complex with 3-(3-(((3-(4-Carboxyphenoxy)benzyl)oxy)methyl)phenyl)-1H-indole-2-carboxylic acid
分子名称: 3-(3-{[3-(4-carboxyphenoxy)phenyl]methoxy}phenyl)-1H-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
著者Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
登録日2020-07-09
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ8
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Receptor for Advanced Glycation End Products VC1 domain in complex with Fragments 1 & 11
分子名称: 3-phenoxyphenol, 7-methyl-3-phenyl-1H-indole-2-carboxylic acid, ACETATE ION, ...
著者Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
登録日2020-07-09
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ5
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Receptor for Advanced Glycation End Products VC1 domain in complex with Fragment 1
分子名称: 7-methyl-3-phenyl-1H-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
著者Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
登録日2020-07-09
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021
6XQ7
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Receptor for Advanced Glycation End Products VC1 domain in complex with Fragment 5
分子名称: 5-bromo-3-methyl-1H-indole-2-carboxylic acid, ACETATE ION, Advanced glycosylation end product-specific receptor, ...
著者Salay, L.E, Kozlyuk, N, Gilston, B.A, Gogliotti, R.D, Christov, P.P, Kim, K, Ovee, M, Waterson, A.G, Chazin, W.J.
登録日2020-07-09
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.
Proteins, 89, 2021

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