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PDB: 99 件

7FGD
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A naturally-occurring neuraminidase-inhibitors-resistant NA from asiatic toad influenza B-like virus
分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, toad NA (OSE)
著者Chai, Y, Wu, Y, Gao, F.
登録日2021-07-26
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7FGC
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A naturally-occurring neuraminidase-inhibitors-resistant NA from asiatic toad influenza B-like virus
分子名称: CALCIUM ION, ZANAMIVIR, toad NA (ZMR)
著者Chai, Y, Wu, Y, Gao, F.
登録日2021-07-26
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7FGB
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A naturally-occurring neuraminidase-inhibitors-resistant NA from asiatic toad influenza B-like virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, SULFATE ION, ...
著者Chai, Y, Wu, Y, Gao, F.
登録日2021-07-26
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7FGE
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A naturally-occurring neuraminidase-inhibitors-resistant NA from asiatic toad influenza B-like virus
分子名称: 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID, CALCIUM ION, toad NA (PER)
著者Chai, Y, Wu, Y, Gao, F.
登録日2021-07-26
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7XVR
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Structure of neuraminidase from influenza B-like viruses derived from spiny eel
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase
著者Chai, Y, Gao, F.
登録日2022-05-24
公開日2023-02-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7XVV
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Structure of neuraminidase from influenza B-like viruses derived from spiny eel
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ...
著者Chai, Y, Gao, F.
登録日2022-05-24
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7XVW
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Structure of neuraminidase from influenza B-like viruses derived from spiny eel
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(1-ACETYLAMINO-2-ETHYL-BUTYL)-4-GUANIDINO-2-HYDROXY-CYCLOPENTANECARBOXYLIC ACID, CALCIUM ION, ...
著者Chai, Y, Gao, F.
登録日2022-05-25
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7XVU
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Structure of neuraminidase from influenza B-like viruses derived from spiny eel
分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Chai, Y, Gao, F.
登録日2022-05-24
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and inhibitor sensitivity analysis of influenza B-like viral neuraminidases derived from Asiatic toad and spiny eel.
Proc.Natl.Acad.Sci.USA, 119, 2022
7YV8
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Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with golden hamster ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike glycoprotein, ...
著者Zhao, Z.N, Xie, Y.F, Chai, Y, Qi, J.X, Gao, G.F.
登録日2022-08-18
公開日2023-07-19
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023
7YVU
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Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with mouse ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1, ...
著者Zhao, Z.N, Xie, Y.F, Chai, Y, Qi, J.X, Gao, G.F.
登録日2022-08-19
公開日2023-07-19
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023
8I5C
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Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK)
分子名称: Beta-2-microglobulin, MHC class I antigen (Fragment), TCR alpha chain, ...
著者Lu, D, Chen, Y, Jiang, M, Tan, S.G, Chai, Y, Gao, G.F.
登録日2023-01-24
公開日2023-08-23
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK)
Nat Commun, 2023
8I5E
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Crystal structure of HLA-A*11:01 in complex with KRAS peptide (VVGAGGVGK)
分子名称: Beta-2-microglobulin, KRAS-G12wt-9, MHC class I antigen (Fragment)
著者Lu, D, Chen, Y, Jiang, M, Tan, S.G, Chai, Y, Gao, G.F.
登録日2023-01-25
公開日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK)
Nat Commun, 2023
7CZE
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BU of 7cze by Molmil
Crystal structure of Epstein-Barr virus (EBV) gHgL and in complex with the ligand binding domian (LBD) of EphA2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ...
著者Su, C, Wu, L.L, Song, H, Chai, Y, Qi, J.X, Yan, J.H, Gao, G.F.
登録日2020-09-08
公開日2020-10-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Molecular basis of EphA2 recognition by gHgL from gammaherpesviruses.
Nat Commun, 11, 2020
6LXK
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Crystal structure of Z2B3 D102R Fab in complex with influenza virus neuraminidase from A/Serbia/NS-601/2014 (H1N1)
分子名称: CALCIUM ION, Heavy chain of Z2B3-D102R Fab, Light chain of Z2B3-D102R Fab, ...
著者Jiang, H, Peng, W, Qi, J, Chai, Y, Song, H, Shi, Y, Gao, G.F, Wu, Y.
登録日2020-02-11
公開日2020-12-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.608 Å)
主引用文献Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus.
Mbio, 11, 2020
6LXJ
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Crystal structure of human Z2B3 Fab in complex with influenza virus neuraminidase from A/Anhui/1/2013 (H7N9)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Heavy chain of Z2B3 Fab, ...
著者Jiang, H, Peng, W, Qi, J, Chai, Y, Song, H, Shi, Y, Gao, G.F, Wu, Y.
登録日2020-02-11
公開日2020-12-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.903 Å)
主引用文献Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus.
Mbio, 11, 2020
6KY9
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Crystal structure of ASFV dUTPase and UMP complex
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, E165R
著者Li, C, Chai, Y, Song, H, Qi, J, Sun, Y, Gao, G.F.
登録日2019-09-17
公開日2019-11-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target.
Mbio, 10, 2019
6LMJ
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ASFV pA104R in complex with double-strand DNA
分子名称: A104R, DNA (5'-D(*TP*GP*CP*TP*TP*AP*TP*CP*AP*AP*TP*TP*TP*GP*TP*TP*GP*CP*A)-3')
著者Wang, H, Qi, J, Chai, Y, Gao, F, Liu, R.
登録日2019-12-25
公開日2020-05-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structural basis of African swine fever virus pA104R binding to DNA and its inhibition by stilbene derivatives.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LMH
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Structure of an ASFV-derived histone-like protein pA104R
分子名称: pA104R
著者Wang, H, Qi, J, Chai, Y, Gao, F.
登録日2019-12-25
公開日2020-05-13
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.805 Å)
主引用文献The structural basis of African swine fever virus pA104R binding to DNA and its inhibition by stilbene derivatives.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LXI
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BU of 6lxi by Molmil
Crystal structure of Z2B3 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)
分子名称: CALCIUM ION, Heavy chain of Z2B3 Fab, Light chain of Z2B3 Fab, ...
著者Jiang, H, Peng, W, Qi, J, Chai, Y, Song, H, Shi, Y, Gao, G.F, Wu, Y.
登録日2020-02-11
公開日2020-12-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus.
Mbio, 11, 2020
6A7W
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Structure of a catalytic domain of the colistin resistance enzyme
分子名称: Putative integral membrane protein, ZINC ION
著者Wang, X.D, Chai, Y, Qi, J.X, Gao, G.F.
登録日2018-07-04
公開日2018-11-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.988 Å)
主引用文献Structural and functional insights into MCR-2 mediated colistin resistance.
Sci China Life Sci, 61, 2018
8WSQ
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A protective human antibody against respiratory syncytial virus by targeting a prefusion epitope across sites IV and V of the viral fusion glycoprotein.
分子名称: Fusion glycoprotein F0, RV11-H scFv, RV11-L scFv
著者Xu, S.Y, Chai, Y.
登録日2023-10-17
公開日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A protective human antibody against respiratory syncytial virus by targeting a prefusion epitope across sites IV and V of the viral fusion glycoprotein.
To Be Published
8WKU
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Complex structure of MjHKU4r-CoV-1 spike RBD bound to human CD26
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4 soluble form, MjHKU4r-CoV-1 spike RBD, ...
著者Zhao, Z.N, Chai, Y, Gao, F.
登録日2023-09-28
公開日2024-06-26
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Molecular basis for receptor recognition and broad host tropism for merbecovirus MjHKU4r-CoV-1.
Embo Rep., 2024
8I5D
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BU of 8i5d by Molmil
Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK)
分子名称: Beta-2-microglobulin, MHC class I antigen (Fragment), TCR alpha chain, ...
著者Lu, D, Chen, Y, Jiang, M, Tan, S.G, Chai, Y, Gao, G.F.
登録日2023-01-25
公開日2023-08-23
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of a TCR in complex with HLA-A*11:01 bound to KRAS peptide (VVGAVGVGK)
Nat Commun, 2023
8GPX
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YFV_E_YD73Fab_postfusion
分子名称: Envelope protein, YD73Fab_H, YD73Fab_K
著者Li, Y, Wu, L, Chai, Y, Qi, J, Yan, J, Gao, G.F.
登録日2022-08-27
公開日2022-11-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献A neutralizing-protective supersite of human monoclonal antibodies for yellow fever virus.
Innovation (N Y), 3, 2022
8GRY
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Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with rat ACE2 (local refinement)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1, ...
著者Zhao, Z.N, Xie, Y.F, Chai, Y, Qi, J.X, Gao, G.F.
登録日2022-09-03
公開日2023-07-19
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants.
Nat Commun, 14, 2023

 

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