8BBS
 
 | | Structure of AKR1C3 in complex with a bile acid fused tetrazole inhibitor | | Descriptor: | (4~{R})-4-[(1~{R},2~{S},5~{R},6~{R},13~{S},14~{S},17~{R},19~{R})-6,14-dimethyl-17-oxidanyl-7,8,9,10-tetrazapentacyclo[11.8.0.0^{2,6}.0^{7,11}.0^{14,19}]henicosa-8,10-dien-5-yl]pentanoic acid, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Petri, E.T, Skerlova, J, Marinovic, M, Brynda, J, Kugler, M, Skoric, D, Bekic, S, Celic, A.S, Rezacova, P. | | Deposit date: | 2022-10-14 | | Release date: | 2023-03-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | X-ray structure of human aldo-keto reductase 1C3 in complex with a bile acid fused tetrazole inhibitor: experimental validation, molecular docking and structural analysis.
Rsc Med Chem, 14, 2023
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2KQ6
 | | The structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity | | Descriptor: | Polycystin-2 | | Authors: | Petri, E.T, Celic, A, Kennedy, S.D, Ehrlich, B.E, Boggon, T.J, Hodsdon, M.E. | | Deposit date: | 2009-10-28 | | Release date: | 2010-05-12 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity.
Proc.Natl.Acad.Sci.USA, 107, 2010
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2MHH
 | | Solution structure of a EF-hand domain from sea urchin polycystin-2 | | Descriptor: | Polycystic kidney disease protein 2 | | Authors: | Kuo, I.Y, Keeler, C, Corbin, R, Celic, A, Petri, E.T, Hodsdon, M.E, Ehrlich, B.E. | | Deposit date: | 2013-11-22 | | Release date: | 2014-10-08 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | The number and location of EF hand motifs dictates the calcium dependence of polycystin-2 function.
Faseb J., 28, 2014
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