1EG6
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![BU of 1eg6 by Molmil](/molmil-images/mine/1eg6) | CRYSTAL STRUCTURE ANALYSIS OF D(CG(5-BRU)ACG) COMPLEXES TO A PHENAZINE | Descriptor: | 5'-D(*CP*GP*(BRO)UP*AP*CP*G)-3', 9-BROMO-PHENAZINE-1-CARBOXYLIC ACID (2-DIMETHYLAMINO-ETHYL)-AMIDE, BROMIDE ION, ... | Authors: | Cardin, C.J, Denny, W.A, Hobbs, J.R, Thorpe, J.H. | Deposit date: | 2000-02-14 | Release date: | 2001-01-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Guanine specific binding at a DNA junction formed by d[CG(5-BrU)ACG](2) with a topoisomerase poison in the presence of Co(2+) ions. Biochemistry, 39, 2000
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3QF8
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![BU of 3qf8 by Molmil](/molmil-images/mine/3qf8) | |
3QRN
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![BU of 3qrn by Molmil](/molmil-images/mine/3qrn) | |
3T86
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![BU of 3t86 by Molmil](/molmil-images/mine/3t86) | d(GCATGCT) + calcium | Descriptor: | CALCIUM ION, DNA (5'-D(*GP*CP*AP*TP*GP*CP*T)-3'), POTASSIUM ION | Authors: | Cardin, C.J, Gan, Y. | Deposit date: | 2011-08-01 | Release date: | 2012-06-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A novel structure for the d(GCATGCT) quadruplex in the presence of nickel and cobalt aqueous cations : comparison with the vanadium, barium and calcium-bound structural motif. To be Published
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3U38
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![BU of 3u38 by Molmil](/molmil-images/mine/3u38) | |
1NT8
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![BU of 1nt8 by Molmil](/molmil-images/mine/1nt8) | Structural Characterisation of the Holliday junction formed by the sequence CCGGTACCGG at 2.00 A | Descriptor: | 5'-d(CpCpGpGpTpApCpCpGpG)-3', CALCIUM ION | Authors: | Cardin, C.J, Gale, B.C, Thorpe, J.H, Texieira, S.C.M, Gan, Y, Moraes, M.I.A.A, Brogden, A.L. | Deposit date: | 2003-01-29 | Release date: | 2003-02-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Analysis of two Holliday Junctions formed by the sequences TCGGTACCGA and CCGGTACCGG To be Published
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1NVN
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![BU of 1nvn by Molmil](/molmil-images/mine/1nvn) | Structural Characterisation of the Holliday junction formed by the sequence CCGGTACCGG at 1.8 A | Descriptor: | 5'-D(CpCpGpGpTpApCpCpGpG)-3', CALCIUM ION | Authors: | Cardin, C.J, Gale, B.C, Thorpe, J.H, Teixeira, S.C.M, Gan, Y, Moraes, M.I.A.A, Brogden, A.L. | Deposit date: | 2003-02-04 | Release date: | 2003-02-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural analysis of two Holliday junctions formed by the sequences TCGGTACCGA and CCGGTACCGG To be Published
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1QYK
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![BU of 1qyk by Molmil](/molmil-images/mine/1qyk) | GCATGCT + Barium | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', BARIUM ION | Authors: | Cardin, C.J, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-11 | Release date: | 2003-10-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Metal Ion Distribution and Stabilization of the DNA Quadruplex Structure Formed by d(GCATGCT) To be published
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1NQS
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![BU of 1nqs by Molmil](/molmil-images/mine/1nqs) | Structural Characterisation of the Holliday Junction formed by the sequence d(TCGGTACCGA) at 1.97 A | Descriptor: | 5'-d(TpCpGpGpTpApCpCpGpA)-3', CALCIUM ION | Authors: | Cardin, C.J, Gale, B.C, Thorpe, J.H, Texieira, S.C.M, Gan, Y, Moraes, M.I.A.A, Brogden, A.L. | Deposit date: | 2003-01-22 | Release date: | 2003-02-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural Analysis of two Holliday junctions formed by the sequences TCGGTACCGA and CCGGTACCGG To be Published
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1NVY
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![BU of 1nvy by Molmil](/molmil-images/mine/1nvy) | |
1QZL
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![BU of 1qzl by Molmil](/molmil-images/mine/1qzl) | GCATGCT + Cobalt | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', COBALT (II) ION | Authors: | Cardin, C.J, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-17 | Release date: | 2003-10-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Metal Ion Distribution and Stabilisation of the DNA Quadruplex Structure Formed by d(GCATGCT) To be published
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1QYL
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![BU of 1qyl by Molmil](/molmil-images/mine/1qyl) | GCATGCT + Vanadium | Descriptor: | 5'-D(*GP*CP*AP*TP*GP*CP*T)-3', VANADIUM ION | Authors: | Cardin, C.J, Gan, Y, Thorpe, J.H, Teixeira, S.C.M, Gale, B.C, Moraes, M.I.A. | Deposit date: | 2003-09-11 | Release date: | 2003-10-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Metal Ion Distribution and Stabilisation of the DNA Quadruplex Structure Formed by d(GCATGCT) To be Published
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6R6D
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![BU of 6r6d by Molmil](/molmil-images/mine/6r6d) | [Ru(TAP)2(11,12-CN2-dppz)]2+ bound to d(TCGGCGCCGA)2 | Descriptor: | BARIUM ION, DNA (5'-D(*TP*CP*GP*GP*CP*GP*CP*CP*GP*A)-3'), Ruthenium (bis-(tetraazaphenanthrene)) (11,12-dicyano-dipyridophenazine), ... | Authors: | McQuaid, K.T, Hall, J.P, Cardin, C.J. | Deposit date: | 2019-03-27 | Release date: | 2020-05-06 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.838 Å) | Cite: | X-ray Crystal Structures Show DNA Stacking Advantage of Terminal Nitrile Substitution in Ru-dppz Complexes. Chemistry, 24, 2018
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7OTB
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![BU of 7otb by Molmil](/molmil-images/mine/7otb) | Ruthenium polypridyl complex bound to a unimolecular chair-form G-quadruplex | Descriptor: | BARIUM ION, DNA (5'-D(*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*TP*GP*GP*G)-3'), POTASSIUM ION, ... | Authors: | McQuaid, K.T, Cardin, C.J, Hall, J.P, Paterson, N.G, Baumgaertner, L. | Deposit date: | 2021-06-09 | Release date: | 2022-04-06 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Ruthenium Polypyridyl Complex Bound to a Unimolecular Chair-Form G-Quadruplex. J.Am.Chem.Soc., 144, 2022
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8CMM
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![BU of 8cmm by Molmil](/molmil-images/mine/8cmm) | Re-pairing DNA - binding of a ruthenium phi complex to a double mismatch | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*AP*TP*AP*AP*TP*GP*CP*G)-3'), LITHIUM ION, POTASSIUM ION, ... | Authors: | Prieto Otoya, T.D, Cardin, C.J, McQuaid, K.M. | Deposit date: | 2023-02-20 | Release date: | 2024-03-06 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Re-pairing DNA: binding of a ruthenium phi complex to a double mismatch. Chem Sci, 15, 2024
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2GB9
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![BU of 2gb9 by Molmil](/molmil-images/mine/2gb9) | d(CGTACG)2 crosslinked bis-acridine complex | Descriptor: | 5'-D(*CP*GP*TP*AP*CP*G)-3', 9,9'-(HEXANE-1,6-DIYLDIIMINO)BIS{N-[2-(DIMETHYLAMINO)ETHYL]ACRIDINE-4-CARBOXAMIDE}, STRONTIUM ION | Authors: | Hopcroft, N.H, Brogden, A.L, Searcey, M, Cardin, C.J. | Deposit date: | 2006-03-10 | Release date: | 2006-04-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | X-ray crystallographic study of DNA duplex cross-linking: simultaneous binding to two d(CGTACG)2 molecules by a bis(9-aminoacridine-4-carboxamide) derivative. Nucleic Acids Res., 34, 2006
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6GLD
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![BU of 6gld by Molmil](/molmil-images/mine/6gld) | |
6G8S
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![BU of 6g8s by Molmil](/molmil-images/mine/6g8s) | [Ru(TAP)2(11,12-CN2-dppz)]2+ bound to d(CCGGACCCGG/CCGGGTCCGG)2 | Descriptor: | BARIUM ION, DNA (5'-D(*CP*CP*GP*GP*AP*CP*CP*CP*GP*G)-3'), DNA (5'-D(*CP*CP*GP*GP*GP*TP*CP*CP*GP*G)-3'), ... | Authors: | McQuaid, K.T, Hall, J.P, Cardin, C.J. | Deposit date: | 2018-04-09 | Release date: | 2019-04-24 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | X-ray Crystal Structures Show DNA Stacking Advantage of Terminal Nitrile Substitution in Ru-dppz Complexes. Chemistry, 24, 2018
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6HWG
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![BU of 6hwg by Molmil](/molmil-images/mine/6hwg) | |
5ET2
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![BU of 5et2 by Molmil](/molmil-images/mine/5et2) | Lambda-Ru(TAP)2(dppz)]2+ bound to d(TTGGCGCCAA) | Descriptor: | BARIUM ION, DNA (5'-D(*(THM)P*TP*GP*GP*CP*GP*CP*CP*AP*A)-3'), Ru(tap)2(dppz) complex | Authors: | Hall, J.P, Cardin, C.J. | Deposit date: | 2015-11-17 | Release date: | 2016-11-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Inosine Can Increase DNA's Susceptibility to Photo-oxidation by a Ru(II) Complex due to Structural Change in the Minor Groove. Chemistry, 23, 2017
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452D
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![BU of 452d by Molmil](/molmil-images/mine/452d) | ACRIDINE BINDING TO DNA | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 9-AMINO-(N-(2-DIMETHYLAMINO)ETHYL)ACRIDINE-4-CARBOXAMIDE, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3') | Authors: | Thorpe, J.H, Todd, A.K, Cardin, C.J. | Deposit date: | 1999-02-18 | Release date: | 2003-03-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethlyamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5Br-U)ACG)2 at 1.3-angstrom resolution J.Med.Chem., 42, 1999
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4RE7
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![BU of 4re7 by Molmil](/molmil-images/mine/4re7) | Lambda-[Ru(TAP)2(dppz)]2+ bound to d(TCIGCGCCGA) | Descriptor: | 5'-D(*TP*CP*IP*GP*CP*GP*CP*CP*GP*A)-3', BARIUM ION, Ru(tap)2(dppz) complex | Authors: | Hall, J.P, Cardin, C.J. | Deposit date: | 2014-09-22 | Release date: | 2015-09-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.181 Å) | Cite: | The effects of DNA modification on the binding of polypyridyl ruthenium complexes To be Published
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4R8J
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![BU of 4r8j by Molmil](/molmil-images/mine/4r8j) | d(TCGGCGCCGA) with lambda-[Ru(TAP)2(dppz)]2+ soaked in D2O | Descriptor: | BARIUM ION, CHLORIDE ION, DNA (5'-D(*(THM)P*CP*GP*GP*CP*GP*CP*CP*GP*A)-3'), ... | Authors: | Hall, J.P, Gurung, S.P, Winter, G.W, Cardin, C.J. | Deposit date: | 2014-09-02 | Release date: | 2015-10-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy. Nat Chem, 7, 2015
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4X18
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![BU of 4x18 by Molmil](/molmil-images/mine/4x18) | [Ru(TAP)2(dppz-11-Me)]2+ bound to d(TCGGCGCCGA) | Descriptor: | (11-methyldipyrido[3,2-a:2',3'-c]phenazine-kappa~2~N~4~,N~5~)[bis(pyrazino[2,3-f]quinoxaline-kappa~2~N~1~,N~10~)]ruthenium, BARIUM ION, CHLORIDE ION, ... | Authors: | Hall, J.P, Cardin, C.J. | Deposit date: | 2014-11-24 | Release date: | 2015-05-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | The Structural Effect of Methyl Substitution on the Binding of Polypyridyl Ru-dppz Complexes to DNA Organometallics, 2015
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4X1A
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![BU of 4x1a by Molmil](/molmil-images/mine/4x1a) | Lambda-[Ru(TAP)2(dppz-10,12-Me)]2+ bound to d(TCGGCGCCGA) | Descriptor: | (10,12-dimethyldipyrido[3,2-a:2',3'-c]phenazine-kappa~2~N~4~,N~5~)[bis(pyrazino[2,3-f]quinoxaline-kappa~2~N~1~,N~10~)]ruthenium, BARIUM ION, DNA (5'-D(*TP*CP*GP*GP*CP*GP*CP*CP*GP*A)-3') | Authors: | Hall, J.P, Cardin, C.J. | Deposit date: | 2014-11-24 | Release date: | 2015-05-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (0.89 Å) | Cite: | The Structural Effect of Methyl Substitution on the Binding of Polypyridyl Ru-dppz Complexes to DNA Organometallics, 2015
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