5QMH
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5QMY
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5QKM
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5QL1
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5QLK
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5QLZ
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5J26
| Crystal structure of a 53BP1 Tudor domain in complex with a ubiquitin variant | Descriptor: | Tumor suppressor p53-binding protein 1, Ubiquitin Variant i53 | Authors: | Wan, L, Canny, M, Juang, Y.C, Durocher, D, Sicheri, F. | Deposit date: | 2016-03-29 | Release date: | 2016-12-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.5047 Å) | Cite: | A genetically encoded inhibitor of 53BP1 to stimulate homology-based gene editing To Be Published
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5XZE
| Mouse cGAS bound to the inhibitor RU332 | Descriptor: | (3R)-3-[1-(3H-1lambda~4~,3-benzothiazol-2-yl)-5-hydroxy-3-methyl-1H-pyrazol-4-yl]-2-benzofuran-1(3H)-one, Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*G)-3'), ... | Authors: | Vincent, J, Adura, C, Gao, P, Luz, A, Lama, L, Asano, Y, Okamoto, R, Imaeda, T, Aida, J, Rothamel, K, Gogakos, T, Steinberg, J, Reasoner, S, Aso, K, Tuschl, T, Patel, D.J, Glickman, J.F, Ascano, M. | Deposit date: | 2017-07-12 | Release date: | 2017-10-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.177 Å) | Cite: | Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nat Commun, 8, 2017
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5QKK
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5QKZ
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5QLD
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5QLT
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5QM8
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5QMN
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5QN2
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5QNH
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5QNZ
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5QOE
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5QKD
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5QKR
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5QL7
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5QLO
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5QM6
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5QML
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5QN1
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