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PDB: 1279 件

3TGN
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Crystal Structure of the zinc-dependent MarR Family Transcriptional Regulator AdcR in the Zn(II)-bound State
分子名称: Adc operon repressor AdcR, ZINC ION
著者Guerra, A.J, Dann III, C.E, Giedroc, D.P.
登録日2011-08-17
公開日2011-11-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Zinc-Dependent MarR Family Transcriptional Regulator AdcR in the Zn(II)-Bound State.
J.Am.Chem.Soc., 133, 2011
1ZVW
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The Crystal Structure of TrpD (Rv2192c) from Mycobacterium tuberculosis in Complex with PRPP and Magnesium
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, BENZAMIDINE, ...
著者Lee, C.E, Lott, J.S, Baker, E.N, Arcus, V.L, Javid-Majd, F, Goodfellow, C, Hung, L.-W, TB Structural Genomics Consortium (TBSGC)
登録日2005-06-02
公開日2006-01-17
最終更新日2021-08-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of TrpD, a Metabolic Enzyme Essential for Lung Colonization by Mycobacterium tuberculosis, in Complex with its Substrate Phosphoribosylpyrophosphate.
J.Mol.Biol., 355, 2006
2ACU
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TYROSINE-48 IS THE PROTON DONOR AND HISTIDINE-110 DIRECTS SUBSTRATE STEREOCHEMICAL SELECTIVITY IN THE REDUCTION REACTION OF HUMAN ALDOSE REDUCTASE: ENZYME KINETICS AND THE CRYSTAL STRUCTURE OF THE Y48H MUTANT ENZYME
分子名称: ALDOSE REDUCTASE, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Bohren, K.M, Grimshaw, C.E, Lai, C.-J, Gabbay, K.H, Petsko, G.A, Harrison, D.H, Ringe, D.
登録日1994-04-15
公開日1994-07-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme.
Biochemistry, 33, 1994
1XMV
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E. coli RecA in complex with MgADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RecA protein
著者Bell, C.E, Xing, X.
登録日2004-10-04
公開日2005-01-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of Escherichia coli RecA in Complex with MgADP and MnAMP-PNP(,).
Biochemistry, 43, 2004
1XMS
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E. coli RecA in complex with MnAMP-PNP
分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, RecA protein
著者Bell, C.E, Xing, X.
登録日2004-10-04
公開日2005-01-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Escherichia coli RecA in Complex with MgADP and MnAMP-PNP(,).
Biochemistry, 43, 2004
1XZ0
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Crystal structure of CD1a in complex with a synthetic mycobactin lipopeptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(HYDROXY-HEXADECANOYL-AMINO)-2-{[(4S)-2-(2-HYDROXY-PHENYL)-4,5-DIHYDRO-OXAZOLE-4-CARBONYL]-AMINO}-HEXANOIC ACID 2-[(3S)-1-(TERT-BUTYL-DIPHENYL-SILANYLOXY)-2-OXO-AZEPAN-3-YLCARBAMOYL]-(1S)-1-METHYL-ETHYL ESTER, Beta-2-microglobulin, ...
著者Zajonc, D.M, Crispin, M.D, Bowden, T.A, Young, D.C, Cheng, T.Y, Hu, J, Costello, C.E, Miller, M.J, Moody, D.B, Wilson, I.A.
登録日2004-11-11
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular Mechanism of Lipopeptide Presentation by CD1a.
Immunity, 22, 2005
2A8V
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RHO TRANSCRIPTION TERMINATION FACTOR/RNA COMPLEX
分子名称: 5'-R(P*CP*CP*C)-3', 5'-R(P*CP*CP*CP*CP*CP*C)-3', RNA BINDING DOMAIN OF RHO TRANSCRIPTION TERMINATION FACTOR
著者Bogden, C.E, Fass, D, Bergman, N, Nichols, M.D, Berger, J.M.
登録日1998-11-08
公開日1999-04-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structural basis for terminator recognition by the Rho transcription termination factor.
Mol.Cell, 3, 1999
2PXG
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NMR Solution Structure of OmlA
分子名称: Outer membrane protein
著者Vanini, M.M.T, Pertinhez, T.A, Sforca, M.L, Spisni, A, Benedetti, C.E.
登録日2007-05-14
公開日2008-01-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The solution structure of the outer membrane lipoprotein OmlA from Xanthomonas axonopodis pv. citri reveals a protein fold implicated in protein-protein interaction.
Proteins, 71, 2008
1XFB
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Human Brain Fructose 1,6-(bis)phosphate Aldolase (C isozyme)
分子名称: Aldolase C
著者Arakaki, T.L, Pezza, J.A, Cronin, M.A, Hopkins, C.E, Zimmer, D.B, Tolan, D.R, Allen, K.N.
登録日2004-09-14
公開日2005-02-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of human brain fructose 1,6-(bis)phosphate aldolase: linking isozyme structure with function
Protein Sci., 13, 2004
1M9I
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Crystal Structure Of Phosphorylation-Mimicking Mutant T356D Of Annexin VI
分子名称: Annexin VI, CALCIUM ION
著者Freye-Minks, C, Kretsinger, R.H, Creutz, C.E.
登録日2002-07-29
公開日2002-08-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural and Dynamic Changes in Human Annexin VI Induced by a Phosphorylation-Mimicking Mutation, T356D
Biochemistry, 42, 2003
2AF8
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ACTINORHODIN POLYKETIDE SYNTHASE ACYL CARRIER PROTEIN FROM STREPTOMYCES COELICOLOR A3(2), NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: ACTINORHODIN POLYKETIDE SYNTHASE ACYL CARRIER PROTEIN
著者Crump, M.P, Crosby, J, Dempsey, C.E, Parkinson, J.A, Murray, M, Hopwood, D.A, Simpson, T.J.
登録日1997-03-23
公開日1997-09-26
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2).
Biochemistry, 36, 1997
7RPS
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B. miyamotoi FbpB complement inhibitory domain
分子名称: Fibronectin-binding lipoprotein FbpB
著者Booth, C.E, Garcia, B.L.
登録日2021-08-04
公開日2022-04-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Borrelia miyamotoi FbpA and FbpB Are Immunomodulatory Outer Surface Lipoproteins With Distinct Structures and Functions.
Front Immunol, 13, 2022
8OK4
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Variant Surface Glycoprotein VSG11wt-Oil
分子名称: Variant surface glycoprotein, alpha-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Zeelen, J.P, Stebbins, C.E, Aresta-Branco, F, Foti, K.
登録日2023-03-27
公開日2023-09-13
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8ONH
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Variant Surface Glycoprotein VSG11wt-Oil
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein, alpha-D-glucopyranose, ...
著者Zeelen, J.P, Stebbins, C.E, Foti, K, Gkeka, A, Vlachou, E.P.
登録日2023-04-03
公開日2023-09-13
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8OK8
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Variant Surface Glycoprotein VSG615
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Variant surface glycoprotein 615, ...
著者Zeelen, J.P, Stebbins, C.E, Chandra, M.
登録日2023-03-27
公開日2023-09-13
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8OK5
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Variant Surface Glycoprotein VSG11 monomer with iodine
分子名称: IODIDE ION, Variant surface glycoprotein, alpha-D-glucopyranose, ...
著者Zeelen, J.P, Stebbins, C.E, Aresta-Branco, F.
登録日2023-03-27
公開日2023-09-13
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8OK6
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Variant Surface Glycoprotein VSG11 two monomers
分子名称: SULFATE ION, Variant surface glycoprotein, alpha-D-glucopyranose, ...
著者Gkeka, A, Vlachou, E.P, Zeelen, J.P, Stebbins, C.E.
登録日2023-03-27
公開日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8OK7
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Variant Surface Glycoprotein VSG558 NTD
分子名称: Variant surface glycoprotein 558, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zeelen, J.P, Stebbins, C.E, van Straaten, M, Zhong, J.
登録日2023-03-27
公開日2023-09-13
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献A structural classification of the variant surface glycoproteins of the African trypanosomey.
Plos Negl Trop Dis, 17, 2023
8ODT
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Structure of TolQR complex from E.coli
分子名称: Tol-Pal system protein TolQ, Tol-Pal system protein TolR
著者Webby, M.N, Kleanthous, C, Press, C.E.
登録日2023-03-09
公開日2023-11-01
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Tunable force transduction through the Escherichia coli cell envelope.
Proc.Natl.Acad.Sci.USA, 120, 2023
6WQ6
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Xanthomonas citri Methionyl-tRNA synthetase in complex with methionine
分子名称: METHIONINE, Methionine--tRNA ligase, ZINC ION
著者Mercaldi, G.F, Benedetti, C.E.
登録日2020-04-28
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium.
J.Biol.Chem., 296, 2021
6WQS
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Xanthomonas citri Methionyl-tRNA synthetase in complex with REP8839
分子名称: 2-{[3-({[4-bromo-5-(1-fluoroethenyl)-3-methylthiophen-2-yl]methyl}amino)propyl]amino}quinolin-4(1H)-one, Methionine--tRNA ligase, ZINC ION
著者Mercaldi, G.F, Benedetti, C.E.
登録日2020-04-29
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium.
J.Biol.Chem., 296, 2021
6WQT
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Xanthomonas citri Methionyl-tRNA synthetase in complex with REP3123
分子名称: 5-[(3-{[(4R)-6,8-dibromo-3,4-dihydro-2H-1-benzopyran-4-yl]amino}propyl)amino]thieno[3,2-b]pyridin-7(6H)-one, Methionine--tRNA ligase, ZINC ION
著者Mercaldi, G.F, Benedetti, C.E.
登録日2020-04-29
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium.
J.Biol.Chem., 296, 2021
6WQI
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Xanthomonas citri Methionyl-tRNA synthetase (apo)
分子名称: Methionine--tRNA ligase, ZINC ION
著者Mercaldi, G.F, Benedetti, C.E.
登録日2020-04-28
公開日2021-04-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular basis for diaryldiamine selectivity and competition with tRNA in a type 2 methionyl-tRNA synthetase from a Gram-negative bacterium.
J.Biol.Chem., 296, 2021
6Y7Z
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Fragment KCL_914 in complex with MAP kinase p38-alpha
分子名称: 1-(1-adamantyl)-3-ethyl-guanidine, 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, CALCIUM ION, ...
著者De Nicola, G.F, Nichols, C.E.
登録日2020-03-02
公開日2020-03-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Fragment KCL_914 in complex with MAP kinase p38-alpha
To Be Published
6Y8I
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Fragment KCL_I013 in complex with IL-1-beta
分子名称: 1-(5-bromanylpyridin-2-yl)-3-(2-hydroxyethyl)urea, Interleukin-1 beta, SULFATE ION
著者De Nicola, G.F, Nichols, C.E.
登録日2020-03-05
公開日2020-06-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Fragment KCL_I013 in complex with IL-1-beta
To Be Published

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件を2024-07-10に公開中

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